Nolan A Wages
Biographic Data
| ID | 7885392 |
|---|---|
| NAME | Nolan A Wages |
| GIVEN NAMES | Nolan A |
| FAMILY NAME | Wages |
| SIGNATURE | WAGES N A |
| AFFILIATIONS | University of Virginia |
| ORCID | 0000-0002-2190-4864 |
| VERIFIED | Yes |
| TOTAL WORKS | 2 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 2 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2012 |
| LATEST PUBLICATION YEAR | 2021 |
| H-INDEX | 0 |
Bayesian Design for Identifying Cohort-Specific Optimal Dose Combinations Based on Multiple Endpoints
Immunotherapy and chemotherapy combinations have proven to be a safe and efficacious treatment approach in multiple settings. However, it is not clear whether approved doses of chemotherapy developed to achieve a maximum tolerated dose are the ideal dose when combining cytotoxic chemotherapy with immunotherapy to induce immune responses. This trial of a modulated dose chemotherapy and Pembrolizumab, with or without a second immunomodulatory agent…
Obtaining the Optimal Dose in Alcohol Dependence Studies
In alcohol dependence studies, the treatment effect at different dose levels remains to be ascertained. Establishing this effect would aid us in identifying the best dose that has satisfactory efficacy while minimizing the rate of adverse events. We advocate the use of dose-finding methodology that has been successfully implemented in the cancer and HIV settings to identify the optimal dose in a cost-effective way. Specifically, we describe the c…
No prominent works on this page.
Obtaining the Optimal Dose in Alcohol Dependence Studies
In alcohol dependence studies, the treatment effect at different dose levels remains to be ascertained. Establishing this effect would aid us in identifying the best dose that has satisfactory efficacy while minimizing the rate of adverse events. We advocate the use of dose-finding methodology that has been successfully implemented in the cancer and HIV settings to identify the optimal dose in a cost-effective way. Specifically, we describe the c…
Bayesian Design for Identifying Cohort-Specific Optimal Dose Combinations Based on Multiple Endpoints
Immunotherapy and chemotherapy combinations have proven to be a safe and efficacious treatment approach in multiple settings. However, it is not clear whether approved doses of chemotherapy developed to achieve a maximum tolerated dose are the ideal dose when combining cytotoxic chemotherapy with immunotherapy to induce immune responses. This trial of a modulated dose chemotherapy and Pembrolizumab, with or without a second immunomodulatory agent…
Medicine (2 works) · Alcohol (1 work) · Alcohol Consumption and Health Effects (1 work) · Alcohol dependence (1 work) · Cancer (1 work) · Cancer Genomics and Diagnostics (1 work) · Cancer Immunotherapy and Biomarkers (1 work) · Carcinogens and Genotoxicity Assessment (1 work) · Chemistry (1 work) · Chemotherapy (1 work)