Alla Polotskaia
Biographic Data
| ID | 7912630 |
|---|---|
| NAME | Alla Polotskaia |
| GIVEN NAMES | Alla |
| FAMILY NAME | Polotskaia |
| SIGNATURE | POLOTSKAIA A |
| AFFILIATIONS | Hunter College |
| VERIFIED | No |
| TOTAL WORKS | 1 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 1 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2015 |
| LATEST PUBLICATION YEAR | 2015 |
| H-INDEX | 0 |
Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient
African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased Poly (ADP ribose) polymerase 1 (PARP1) on the chromatin i…
No prominent works on this page.
Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient
African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased Poly (ADP ribose) polymerase 1 (PARP1) on the chromatin i…
Biology (1 work) · Breast cancer (1 work) · Cancer (1 work) · Cancer Genomics and Diagnostics (1 work) · Cancer Research (1 work) · Cancer-related Molecular Pathways (1 work) · Cell culture (1 work) · Gene (1 work) · Gene knockdown (1 work) · Genetics (1 work)