Kirsten Jahn
Biographic Data
| ID | 7962881 |
|---|---|
| NAME | Kirsten Jahn |
| GIVEN NAMES | Kirsten |
| FAMILY NAME | Jahn |
| SIGNATURE | JAHN K |
| AFFILIATIONS | Medizinische Hochschule Hannover |
| ORCID | 0000-0002-2760-1602 |
| VERIFIED | Yes |
| TOTAL WORKS | 3 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 3 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 0 |
Determinants of severe QTc prolongation in a real-world gerontopsychiatric setting
Introduction QT c prolongation carries the risk of ventricular tachyarrhythmia (Torsades de Pointes) and sudden cardiac death. Psychotropic drugs can affect ventricular repolarization and thus prolong the QT c interval. The present study sought to investigate the risk factors (pharmacological and non-pharmacological) of severe QT c prolongation in gerontopsychiatric patients. Methods Electrocardiograms of patients on a gerontopsychiatric ward wer…
DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy
Background Major Depressive Disorder (MDD) represents a tremendous health threat to the world’s population. Electroconvulsive therapy (ECT) is the most effective treatment option for refractory MDD patients. Ample evidence suggests brain-derived neurotrophic factor (BDNF) to play a crucial role in ECT ́s mode of action. Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) are involved in BDNF production. Hypothes…
Association of Leptin Gene DNA Methylation With Diagnosis and Treatment Outcome of Anorexia Nervosa
Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia nervosa (AN) but are as yet poorly understood. We investigated possible associations between the leptin gene ( LEP ) and the leptin receptor gene ( LEPR ) DNA promoter methylation and (1) a diagnosis of AN and (2) outcome after a 10 months psychotherapeutic outpatient treatment. 129 ( LEPR : n = 135) patients with AN were investigated during the large scale psyc…
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Association of Leptin Gene DNA Methylation With Diagnosis and Treatment Outcome of Anorexia Nervosa
Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia nervosa (AN) but are as yet poorly understood. We investigated possible associations between the leptin gene ( LEP ) and the leptin receptor gene ( LEPR ) DNA promoter methylation and (1) a diagnosis of AN and (2) outcome after a 10 months psychotherapeutic outpatient treatment. 129 ( LEPR : n = 135) patients with AN were investigated during the large scale psyc…
DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy
Background Major Depressive Disorder (MDD) represents a tremendous health threat to the world’s population. Electroconvulsive therapy (ECT) is the most effective treatment option for refractory MDD patients. Ample evidence suggests brain-derived neurotrophic factor (BDNF) to play a crucial role in ECT ́s mode of action. Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) are involved in BDNF production. Hypothes…
Determinants of severe QTc prolongation in a real-world gerontopsychiatric setting
Introduction QT c prolongation carries the risk of ventricular tachyarrhythmia (Torsades de Pointes) and sudden cardiac death. Psychotropic drugs can affect ventricular repolarization and thus prolong the QT c interval. The present study sought to investigate the risk factors (pharmacological and non-pharmacological) of severe QT c prolongation in gerontopsychiatric patients. Methods Electrocardiograms of patients on a gerontopsychiatric ward wer…
Internal Medicine (3 works) · Medicine (3 works) · Biology (2 works) · DNA methylation (2 works) · Epigenetics (2 works) · Gene (2 works) · Gene expression (2 works) · Genetics (2 works) · Methylation (2 works) · Adolescent and Pediatric Healthcare (1 work)