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Guohong Cai

Biographic Data

ID7963711
NAMEGuohong Cai
GIVEN NAMESGuohong
FAMILY NAMECai
SIGNATURECAI G
AFFILIATIONSAir Force Medical University
ORCID0000-0001-7511-7420
VERIFIEDYes
TOTAL WORKS3
TOTAL CITATIONS0
AUTHOR COUNT3
EDITOR COUNT0
FIRST PUBLICATION YEAR2019
LATEST PUBLICATION YEAR2022
H-INDEX0
  • Glutamatergic Neurons in the Amygdala Are Involved in Paclitaxel-Induced Pain and Anxiety

    Open Access•Jiaxin Liu, Dangchao Li et al.•ARTICLE•Frontiers in Psychiatry•2022

    Paclitaxel is widely used as a first-line chemotherapy agent to treat malignant tumors. However, paclitaxel causes peripheral nerve fiber damage and neuropathic pain in some patients. In addition, patients received paclitaxel chemotherapy are often accompanied by negative emotions such as anxiety. The amygdala is critically involved in regulating pain signals, as well as anxiety. The purpose of this study is to clarify the role of Ca 2+ /calmodul…

  • Analysis of the Gut Microbiota and Inflammatory Factors in mGluR5-Knockout Mice

    Open Access•Guohong Cai, Yuanyuan Zhu et al.•ARTICLE•Frontiers in Psychiatry•2020

    In conclusion, we deduced that mGluR5 -/- mice are susceptible to despair-like behavior. The systemic knockout of mGluR5 did not affect the gut microbiota or inflammatory factors in mice

  • Brain mGluR5 in Shank3B−/− Mice Studied With in vivo [18F]FPEB PET Imaging and ex vivo Immunoblotting

    Open Access•Guohong Cai, Mengmeng Wang et al.•ARTICLE•Frontiers in Psychiatry•2019

    Although several studies have found that metabotropic glutamate 5 receptor (mGluR5) may play an important role in autism spectrum disorders (ASD), the mechanisms remain unclear. Here, we used a Shank3 gene complete knockout mouse model (Shank3B -/- ) to explore the change in mGluR5 in the brain. To assess whether deletion of Shank3 in mice results in ASD-like behavior, we conducted a battery of behavioral experiments to characterize Shank3B -/- m…

No prominent works on this page.

  • Brain mGluR5 in Shank3B−/− Mice Studied With in vivo [18F]FPEB PET Imaging and ex vivo Immunoblotting

    Open Access•Guohong Cai, Mengmeng Wang et al.•ARTICLE•Frontiers in Psychiatry•2019

    Although several studies have found that metabotropic glutamate 5 receptor (mGluR5) may play an important role in autism spectrum disorders (ASD), the mechanisms remain unclear. Here, we used a Shank3 gene complete knockout mouse model (Shank3B -/- ) to explore the change in mGluR5 in the brain. To assess whether deletion of Shank3 in mice results in ASD-like behavior, we conducted a battery of behavioral experiments to characterize Shank3B -/- m…

  • Analysis of the Gut Microbiota and Inflammatory Factors in mGluR5-Knockout Mice

    Open Access•Guohong Cai, Yuanyuan Zhu et al.•ARTICLE•Frontiers in Psychiatry•2020

    In conclusion, we deduced that mGluR5 -/- mice are susceptible to despair-like behavior. The systemic knockout of mGluR5 did not affect the gut microbiota or inflammatory factors in mice

  • Glutamatergic Neurons in the Amygdala Are Involved in Paclitaxel-Induced Pain and Anxiety

    Open Access•Jiaxin Liu, Dangchao Li et al.•ARTICLE•Frontiers in Psychiatry•2022

    Paclitaxel is widely used as a first-line chemotherapy agent to treat malignant tumors. However, paclitaxel causes peripheral nerve fiber damage and neuropathic pain in some patients. In addition, patients received paclitaxel chemotherapy are often accompanied by negative emotions such as anxiety. The amygdala is critically involved in regulating pain signals, as well as anxiety. The purpose of this study is to clarify the role of Ca 2+ /calmodul…

Medicine (3 works) · Neuroscience (3 works) · Psychology (3 works) · Biology (2 works) · Glutamate receptor (2 works) · Glutamatergic (2 works) · Internal Medicine (2 works) · Open field (2 works) · Psychiatry (2 works) · Receptor (2 works)

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