Piotr Paweł Chmielewski
Biographic Data
| ID | 808515 |
|---|---|
| NAME | Piotr Paweł Chmielewski |
| GIVEN NAMES | Piotr Paweł |
| FAMILY NAME | Chmielewski |
| SIGNATURE | CHMIELEWSKI P P |
| AFFILIATIONS | Wroclaw Medical University |
| ORCID | 0000-0002-6995-123X |
| VERIFIED | Yes |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 16 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2015 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
The Association of Body Temperature with Longevity
Effective thermoregulation is crucial for maintaining homeostasis. Previous research has suggested a link between lower steady-state body temperature and longevity, particularly in physically healthy, nonobese older adults. However, the exact mechanisms behind this relationship remain unclear. Despite the physiological insights gained from studies on body temperature, limited attention has been given to its potential role as a biomarker of longev…
Do the short die young? Evidence from a large sample of deceased Polish adults
Body height is associated with various socioeconomic and health-related outcomes. Despite numerous studies, the relationship between stature and longevity remains uncertain. This study explores the association between self-reported height and lifespan. Data from 848,860 adults who died between 2004 and 2008 in Poland were collected. After excluding a small proportion of records due to missing data or errors, we examined records for 848,387 indivi…
Exploring the effects of birth order on human lifespan in Polish historical populations, 1738-1968
While the relationships between birth order and later outcomes in life, including health and wealth, have been the subject of investigation for several decades, little or no data exist regarding the relationship between birth order and life expectancy in the Polish population. The aim of this study was to explore the link between birth order and lifespan in Polish historical populations. We obtained 8523 records from a historical dataset that was…
If ageing is a disease, then life is also a disease
Ageing is distinct from a disease. Sound arguments have been adduced to explain that senescence cannot be understood as a pathological process. Nevertheless, this distinction is believed to be artificial (Holliday 1995), and other eminent researchers argue that the senescence-pathology dichotomy is also misleading. Recently, it has been suggested that ageing should be classified as a complex pathological syndrome or a ‘pre-disease’ that is treata…
From gerontology to geroscience
Biological ageing can be tentatively defined as an intrinsic and inevitable degradation of biological function that accumulates over time at every level of biological organisation from molecules to populations. Senescence is characterised by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. With advancing age, all components of the human body undergo these cumulative, universal, prog…
The dynamic nature of ageing
Ageing is one of the most complex and difficult problems for humans to face and for science to solve. Although human senescence was viewed as a passive and uncontrollable process of deterioration over time with little or no genetic regulation, the concept that ageing is caused by both genetic and environmental factors is now generally accepted, even though it remains difficult to distinguish between ageing sensu stricto and the effects of age-re…
Human ageing, longevity and evolution
Understanding the proximate and ultimate causes of ageing is one of the key challenges in current biology and medicine. These problems are so important that they are sometimes referred to as the Holy Grail of biology and the Great Conundrum in biogerontology. From an evolutionary perspective, ageing is due to a failure of selection that is caused either by declining strength of selection after the onset of sexual reproduction (Medawar’s theory an…
Association of serum bilirubin with longevity
Bilirubin is a potent antioxidant and an important anti-inflammatory factor. Therefore, there has been an increasing focus on serum bilirubin as a negative risk factor of cardiovascular mortality in men and an indicator of improved survival in both sexes, but the direct mechanisms of these links and the causes of sex differences are not well understood. Moreover, the evidence from longitudinal studies on effects of bilirubin on longevity is limit…
Rethinking modern theories of ageing and their classification
For a very long time, ageing has been an insurmountable problem in biology. The collection of age-dependent changes that render ageing individuals progressively more likely to die seemed to be an intractable labyrinth of alterations and associations whose direct mechanisms and ultimate explanations were too complex and difficult to understand. The science of ageing has always been fraught with insuperable problems and obstacles. In 1990, Zhores M…
Association between body size and selected hematological parameters in men and women aged 45 and above from a hospitalized population of older adults
In elderly people, anemia occurs with increasing frequency with each advancing decade and can be a harbinger of very serious health conditions, including gastrointestinal bleeding, gastric and duodenal ulcers, and cancer. Therefore, age-dependant changes in hematological parameters deserve special attention. Nonetheless, very few longitudinal studies of aging have focused on possible associations between basic anthropometric characteristics and h…
Contemporary views on human aging and longevity
Aging is currently stimulating intense interest of both researchers and the general public. In developed countries, the average life expectancy has increased by roughly 30 years within the last century, and human senescence has been delayed by around a decade. Although aging is arguably the most familiar aspect of human biology, its proximate and ultimate causes have not been elucidated fully and understood yet. Nowadays there are two main approa…
Understanding the links between month of birth, body height, and longevity
There is a lack of agreement in the literature as to whether adult height depends on month of birth and whether height affects lifespan. Additionally, the relationship between stature and longevity involves conflicting findings and the results remain mixed due to several confounders, such as: year of birth, somatotype, relative body weight, genetic inheritance, diet, diseases, etc. Here, we hypothesize that the season of birth effect can also be …
Effects of aging on the function of the urinary system
Although normal aging does not have a pernicious effect on the homeostasis of fluids, renal reserve in elderly people can be depleted. The purpose of the present study was to assess the relationship between longitudinal changes with age in basic urine parameters (specific gravity and pH) in older men and women, depending on their body height and relative body weight. Longitudinal data on these two quantitative traits of the urine were available f…
The relationship between adult stature and longevity
Early epidemiological studies demonstrated that short stature is associated with cardiovascular disease (CVD), diabetes, lower energy intake or food deprivation during growth, poor health, and increased all-cause mortality. Nevertheless, the links between adult height and longevity become tenuous if certain confounders (e.g. BMI, SES, educational attainment, etc.) are allowed for. Furthermore, numerous studies have found that like excess weight, …
Longitudinal and cross-sectional changes with age in selected anthropometric and physiological traits in hospitalized adults
Longitudinal studies of aging concerning individuals with comparable lifestyle, diet, health profile, socioeconomic status, and income remain extraordinarily rare. The purposes of our ongoing project are as follows: (i) to collect extensive data on biological and medical aspects of aging in the Polish population, (ii) to determine factors affecting the rate and course of aging, (iii) to understand how aging unfolds as a dynamic and malleable proc…
Height loss with advancing age in a hospitalized population of Polish men and women
The connection between the rate of height loss in older people and their general health status has been well documented in the medical literature. Our study was aimed at furthering the characterization of this interrelationship in the context of health indices and mortality in a hospitalized population of Polish adults. Data were collated from a literature review and from a longitudinal study of aging carried out in the Polish population which fo…
The Association of Body Temperature with Longevity
Effective thermoregulation is crucial for maintaining homeostasis. Previous research has suggested a link between lower steady-state body temperature and longevity, particularly in physically healthy, nonobese older adults. However, the exact mechanisms behind this relationship remain unclear. Despite the physiological insights gained from studies on body temperature, limited attention has been given to its potential role as a biomarker of longev…
Longitudinal and cross-sectional changes with age in selected anthropometric and physiological traits in hospitalized adults
Longitudinal studies of aging concerning individuals with comparable lifestyle, diet, health profile, socioeconomic status, and income remain extraordinarily rare. The purposes of our ongoing project are as follows: (i) to collect extensive data on biological and medical aspects of aging in the Polish population, (ii) to determine factors affecting the rate and course of aging, (iii) to understand how aging unfolds as a dynamic and malleable proc…
Height loss with advancing age in a hospitalized population of Polish men and women
The connection between the rate of height loss in older people and their general health status has been well documented in the medical literature. Our study was aimed at furthering the characterization of this interrelationship in the context of health indices and mortality in a hospitalized population of Polish adults. Data were collated from a literature review and from a longitudinal study of aging carried out in the Polish population which fo…
Contemporary views on human aging and longevity
Aging is currently stimulating intense interest of both researchers and the general public. In developed countries, the average life expectancy has increased by roughly 30 years within the last century, and human senescence has been delayed by around a decade. Although aging is arguably the most familiar aspect of human biology, its proximate and ultimate causes have not been elucidated fully and understood yet. Nowadays there are two main approa…
Understanding the links between month of birth, body height, and longevity
There is a lack of agreement in the literature as to whether adult height depends on month of birth and whether height affects lifespan. Additionally, the relationship between stature and longevity involves conflicting findings and the results remain mixed due to several confounders, such as: year of birth, somatotype, relative body weight, genetic inheritance, diet, diseases, etc. Here, we hypothesize that the season of birth effect can also be …
Effects of aging on the function of the urinary system
Although normal aging does not have a pernicious effect on the homeostasis of fluids, renal reserve in elderly people can be depleted. The purpose of the present study was to assess the relationship between longitudinal changes with age in basic urine parameters (specific gravity and pH) in older men and women, depending on their body height and relative body weight. Longitudinal data on these two quantitative traits of the urine were available f…
The relationship between adult stature and longevity
Early epidemiological studies demonstrated that short stature is associated with cardiovascular disease (CVD), diabetes, lower energy intake or food deprivation during growth, poor health, and increased all-cause mortality. Nevertheless, the links between adult height and longevity become tenuous if certain confounders (e.g. BMI, SES, educational attainment, etc.) are allowed for. Furthermore, numerous studies have found that like excess weight, …
Association of serum bilirubin with longevity
Bilirubin is a potent antioxidant and an important anti-inflammatory factor. Therefore, there has been an increasing focus on serum bilirubin as a negative risk factor of cardiovascular mortality in men and an indicator of improved survival in both sexes, but the direct mechanisms of these links and the causes of sex differences are not well understood. Moreover, the evidence from longitudinal studies on effects of bilirubin on longevity is limit…
Rethinking modern theories of ageing and their classification
For a very long time, ageing has been an insurmountable problem in biology. The collection of age-dependent changes that render ageing individuals progressively more likely to die seemed to be an intractable labyrinth of alterations and associations whose direct mechanisms and ultimate explanations were too complex and difficult to understand. The science of ageing has always been fraught with insuperable problems and obstacles. In 1990, Zhores M…
Association between body size and selected hematological parameters in men and women aged 45 and above from a hospitalized population of older adults
In elderly people, anemia occurs with increasing frequency with each advancing decade and can be a harbinger of very serious health conditions, including gastrointestinal bleeding, gastric and duodenal ulcers, and cancer. Therefore, age-dependant changes in hematological parameters deserve special attention. Nonetheless, very few longitudinal studies of aging have focused on possible associations between basic anthropometric characteristics and h…
Human ageing, longevity and evolution
Understanding the proximate and ultimate causes of ageing is one of the key challenges in current biology and medicine. These problems are so important that they are sometimes referred to as the Holy Grail of biology and the Great Conundrum in biogerontology. From an evolutionary perspective, ageing is due to a failure of selection that is caused either by declining strength of selection after the onset of sexual reproduction (Medawar’s theory an…
If ageing is a disease, then life is also a disease
Ageing is distinct from a disease. Sound arguments have been adduced to explain that senescence cannot be understood as a pathological process. Nevertheless, this distinction is believed to be artificial (Holliday 1995), and other eminent researchers argue that the senescence-pathology dichotomy is also misleading. Recently, it has been suggested that ageing should be classified as a complex pathological syndrome or a ‘pre-disease’ that is treata…
From gerontology to geroscience
Biological ageing can be tentatively defined as an intrinsic and inevitable degradation of biological function that accumulates over time at every level of biological organisation from molecules to populations. Senescence is characterised by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. With advancing age, all components of the human body undergo these cumulative, universal, prog…
The dynamic nature of ageing
Ageing is one of the most complex and difficult problems for humans to face and for science to solve. Although human senescence was viewed as a passive and uncontrollable process of deterioration over time with little or no genetic regulation, the concept that ageing is caused by both genetic and environmental factors is now generally accepted, even though it remains difficult to distinguish between ageing sensu stricto and the effects of age-re…
Exploring the effects of birth order on human lifespan in Polish historical populations, 1738-1968
While the relationships between birth order and later outcomes in life, including health and wealth, have been the subject of investigation for several decades, little or no data exist regarding the relationship between birth order and life expectancy in the Polish population. The aim of this study was to explore the link between birth order and lifespan in Polish historical populations. We obtained 8523 records from a historical dataset that was…
Do the short die young? Evidence from a large sample of deceased Polish adults
Body height is associated with various socioeconomic and health-related outcomes. Despite numerous studies, the relationship between stature and longevity remains uncertain. This study explores the association between self-reported height and lifespan. Data from 848,860 adults who died between 2004 and 2008 in Poland were collected. After excluding a small proportion of records due to missing data or errors, we examined records for 848,387 indivi…
The Association of Body Temperature with Longevity
Effective thermoregulation is crucial for maintaining homeostasis. Previous research has suggested a link between lower steady-state body temperature and longevity, particularly in physically healthy, nonobese older adults. However, the exact mechanisms behind this relationship remain unclear. Despite the physiological insights gained from studies on body temperature, limited attention has been given to its potential role as a biomarker of longev…
Medicine (15 works) · Gerontology (12 works) · Demography (10 works) · Genetics, Aging, and Longevity in Model Organisms (10 works) · Longevity (9 works) · Population (9 works) · Biology (7 works) · Internal Medicine (6 works) · Pathology (6 works) · Ageing (5 works)