Bernadette Modell

Biographic Data

ID8210612
NAMEBernadette Modell
GIVEN NAMESBernadette
FAMILY NAMEModell
SIGNATUREMODELL B
AFFILIATIONSUniversity College London
VERIFIEDNo
TOTAL WORKS9
TOTAL CITATIONS0
AUTHOR COUNT9
EDITOR COUNT0
FIRST PUBLICATION YEAR1997
LATEST PUBLICATION YEAR2021
H-INDEX0

  • Modelled epidemiological data for selected congenital disorders in South Africa

    Open AccessHelen Louise Malherbe, Colleen Aldous et al.ARTICLEJournal of Community Genetics2021

  • Methods to estimate access to care and the effect of interventions on the outcomes of congenital disorders

    Open AccessHannah Blencowe, Sowmiya Moorthie et al.ARTICLEJournal of Community Genetics2018

    In the absence of intervention, early-onset congenital disorders lead to pregnancy loss, early death, or disability. Currently, lack of epidemiological data from many settings limits the understanding of the burden of these conditions, thus impeding health planning, policy-making, and commensurate resource allocation. The Modell Global Database of Congenital Disorders (MGDb) seeks to meet this need by combining general biological principles with …

  • Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide

    Open AccessSowmiya Moorthie, Hannah Blencowe et al.ARTICLEJournal of Community Genetics2018

    Congenital anomaly registries have two main surveillance aims: firstly to define baseline epidemiology of important congenital anomalies to facilitate programme, policy and resource planning, and secondly to identify clusters of cases and any other epidemiological changes that could give early warning of environmental or infectious hazards. However, setting up a sustainable registry and surveillance system is resource-intensive requiring national…

  • Rare single gene disorders

    Open AccessHannah Blencowe, Sowmiya Moorthie et al.ARTICLEJournal of Community Genetics2018

    As child mortality rates overall are decreasing, non-communicable conditions, such as genetic disorders, constitute an increasing proportion of child mortality, morbidity and disability. To date, policy and public health programmes have focused on common genetic disorders. Rare single gene disorders are an important source of morbidity and premature mortality for affected families. When considered collectively, they account for an important publi…

  • Historical overview of development in methods to estimate burden of disease due to congenital disorders

    Open AccessBernadette Modell, Matthew Darlison et al.ARTICLEJournal of Community Genetics2018

    Congenital disorders (often also called birth defects) are an important cause of mortality and disability. They encompass a wide range of disorders with differing severity that can affect any aspect of structure or function. Understanding their epidemiology is important in developing appropriate services both for their prevention and treatment. The need for epidemiological data on congenital disorders has been recognised for many decades. Here, w…

  • An overview of concepts and approaches used in estimating the burden of congenital disorders globally

    Open AccessSowmiya Moorthie, Hannah Blencowe et al.ARTICLEJournal of Community Genetics2017

    Congenital disorders are an important cause of pregnancy loss, premature death and life-long disability. A range of interventions can greatly reduce their burden, but the absence of local epidemiological data on their prevalence and the impact of interventions impede policy and service development in many countries. In an attempt to overcome these deficiencies, we have developed a tool-The Modell Global Database of Congenital Disorders (MGDb) tha…

  • Chromosomal disorders

    Open AccessSowmiya Moorthie, Hannah Blencowe et al.ARTICLEJournal of Community Genetics2017

    Chromosomal disorders, of which Down syndrome is the most common, can cause multi-domain disability. In addition, compared to the general population, there is a higher frequency of death before the age of five. In many settings, large gaps in data availability have hampered policy-making, programme priorities and resource allocation for these important conditions. We have developed methods, which overcome this lack of data and allow estimation of…

  • Falling prevalence of beta-thalassaemia and eradication of malaria in the Maldives

    Open AccessNaila Firdous, Stephen Gibbons et al.ARTICLEJournal of Community Genetics2011

  • Kinship and Medical Genetics

    Open AccessBernadette ModellCHAPTERCulture, Kinship and Genes1997

    This article is written from the point of view of a clinician whose main clinical interest for 30 years has been treatment and prevention of the haemoglobin disorders (Modell & Berdoukas 1984). This has involved regular contacts with people from most of the main ethnic minority groups in the UK, and has permitted some understanding of the way that kinship patterns can affect a family’s ability to cope with inherited disease and their use of genet…