George Mastorakos

Biographic Data

ID8220486
NAMEGeorge Mastorakos
GIVEN NAMESGeorge
FAMILY NAMEMastorakos
SIGNATUREMASTORAKOS G
AFFILIATIONSNational and Kapodistrian University of Athens
ORCID0000-0002-1929-3275
VERIFIEDYes
TOTAL WORKS5
TOTAL CITATIONS0
WORKS AS AUTHOR5
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2022
LATEST PUBLICATION YEAR2023
H-INDEX0

  • Secondary Prevention of Diabetes Type 1 with Oral Calcitriol and Analogs, the PRECAL Study

    Open AccessDimitrios T Papadimitriou, Eleni Dermitzaki et al.ARTICLEChildren2023

    Screening for Type 1 Diabetes (T1D, incidence 1:300) with T1D autoantibodies (T1Ab) at ages 2 and 6, while sensitive, lacks a preventive strategy. Cholecalciferol 2000 IU daily since birth reduced T1D by 80% at 1 year. T1D-associated T1Ab negativized within 0.6 years with oral calcitriol in 12 children. To further investigate secondary prevention of T1D with calcitriol and its less calcemic analog, paricalcitol, we initiated a prospective interve…

  • A Novel Variant in the TP53 Gene Causing Li–Fraumeni Syndrome

    Open AccessDimitrios T Papadimitriou, Constantine A Stratakis et al.ARTICLEChildren2023

    Li-Fraumeni syndrome (LFS) is an autosomal dominant hereditary cancer syndrome associated with germline pathogenic variants in the tumor protein p53 ( TP53 ) gene and elevated risk of a broad range of early-onset malignancies. Patients with LFS are at risk of a second and third primary tumor. A 15-month-old girl consulted for clitoromegaly and pubic hair. Adrenal ultrasound detected a large left adrenal tumor. Left total adrenalectomy confirmed a…

  • Identification of the Rare Ala871Glu Mutation in the Androgen Receptor Gene Leading to Complete Androgen Insensitivity Syndrome in an Adolescent Girl with Primary Amenorrhea

    Open AccessAikaterini Kapama, Dimitrios T Papadimitriou et al.ARTICLEChildren2022

    Complete Androgen Insensitivity Syndrome (CAIS) is a rare genetic condition by mutations in the androgen receptor (AR) gene resulting in target issue resistance to androgens and a female phenotype in genetically male individuals. A 16-year-old phenotypically female individual presented to our clinic with primary amenorrhea. Her clinical evaluation showed normal female external genitalia, Tanner III breast development and sparse pubic and axillary…

  • The Role of Exercise on Cardiometabolic Profile and Body Composition in Youth with Type 1 Diabetes

    Open AccessMaria Kaza, Charalampos Tsentidis et al.ARTICLEChildren2022

    Exercise has a direct positive effect on glycemic control by promoting insulin secretion from β-pancreatic islet-cells and by increasing skeletal muscle glucose uptake. The reduction in daily insulin needs and the optimization of glycemic control improves the patient's quality of life, self-esteem, mental wellness, as well as diabetes-related mobility and mortality. The aim of this study was to investigate the effect of physical activity in child…

  • The Effect of Metabolic Profile on Leptin, Adiponectin, and hs-CRP in Children and Adolescents with Type 1 Diabetes

    Open AccessMaria Kaza, Charalampos Tsentidis et al.ARTICLEChildren2022

    Adipokines are a superfamily of cell signaling proteins produced by the adipose tissue. This study’s purpose was to reveal the association of adipokines (leptin, adiponectin), hs-CRP, and IL-6 with well-known cardiovascular risk factors (lipid profile, diabetes control, obesity, physical activity) in children and adolescents with T1D. This cross-sectional study included 80 participants (36 boys) with T1D, aged (mean ± SD) 14.8 ± 3.4 years. Body M…