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Nobuo Kanazawa

Biographic Data

ID8255483
NAMENobuo Kanazawa
GIVEN NAMESNobuo
FAMILY NAMEKanazawa
SIGNATUREKANAZAWA N
AFFILIATIONSHyogo Medical University
ORCID0000-0003-3000-9711
VERIFIEDYes
TOTAL WORKS3
TOTAL CITATIONS0
WORKS AS AUTHOR3
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2021
LATEST PUBLICATION YEAR2022
H-INDEX0
  • Dupilumab Improves Pruritus in Netherton Syndrome

    Open Access•Yutaka Inaba, Nobuo Kanazawa et al.•ARTICLE•Children•2022

    The patient was a 26-year-old male. He had red and scaling skin of the entire body since birth, as well as an elevated level of serum IgE. Genetic testing revealed a mutation in the SPINK5 gene, which had confirmed the diagnosis with Netherton syndrome. He has had significant pruritis since birth, and subsequently had symptoms of sleeping disorders and concentration difficulty throughout the day. Since treatment with various antihistamines were n…

  • NOD2 Mutation-Associated Case with Blau Syndrome Triggered by BCG Vaccination

    Open Access•Akiko Arakawa, Naotomo Kambe et al.•ARTICLE•Children•2021

    We describe a patient who developed multiple granulomatous skin lesions after Bacille de Calmette et Guérin (BCG) vaccination without significant effect by topical corticosteroid, followed by painless cystic tumors on the bilateral knees and hands and inflammatory changes on ophthalmologic examination. A functional mutation in NOD 2 was detected by a genetic analysis, and he was diagnosed as sporadic Blau syndrome. Since NOD 2 acts as a sensor fo…

  • Sustained Surface Icam-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated NOD2 Mutations

    Open Access•Mizuho Nishiyama, Li Hongjin et al.•ARTICLE•Children•2021

    Sustained surface ICAM-1 expression and transient PDGF-B production by newly differentiating macrophages harboring mutant NOD2 might play a role in granuloma formation in Blau syndrome

No prominent works on this page.

  • NOD2 Mutation-Associated Case with Blau Syndrome Triggered by BCG Vaccination

    Open Access•Akiko Arakawa, Naotomo Kambe et al.•ARTICLE•Children•2021

    We describe a patient who developed multiple granulomatous skin lesions after Bacille de Calmette et Guérin (BCG) vaccination without significant effect by topical corticosteroid, followed by painless cystic tumors on the bilateral knees and hands and inflammatory changes on ophthalmologic examination. A functional mutation in NOD 2 was detected by a genetic analysis, and he was diagnosed as sporadic Blau syndrome. Since NOD 2 acts as a sensor fo…

  • Sustained Surface Icam-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated NOD2 Mutations

    Open Access•Mizuho Nishiyama, Li Hongjin et al.•ARTICLE•Children•2021

    Sustained surface ICAM-1 expression and transient PDGF-B production by newly differentiating macrophages harboring mutant NOD2 might play a role in granuloma formation in Blau syndrome

  • Dupilumab Improves Pruritus in Netherton Syndrome

    Open Access•Yutaka Inaba, Nobuo Kanazawa et al.•ARTICLE•Children•2022

    The patient was a 26-year-old male. He had red and scaling skin of the entire body since birth, as well as an elevated level of serum IgE. Genetic testing revealed a mutation in the SPINK5 gene, which had confirmed the diagnosis with Netherton syndrome. He has had significant pruritis since birth, and subsequently had symptoms of sleeping disorders and concentration difficulty throughout the day. Since treatment with various antihistamines were n…

Autoimmune and Inflammatory Disorders (2 works) · Biology (2 works) · Dermatology (2 works) · Genetics (2 works) · Immune system (2 works) · Immunology (2 works) · Medicine (2 works) · NOD2 (2 works) · Sarcoidosis and Beryllium Toxicity Research (2 works) · Adverse effect (1 work)

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