Suresh G Killedar
Biographic Data
| ID | 8375942 |
|---|---|
| NAME | Suresh G Killedar |
| GIVEN NAMES | Suresh G |
| FAMILY NAME | Killedar |
| SIGNATURE | KILLEDAR S G |
| AFFILIATIONS | Shivaji University |
| ORCID | 0000-0001-7017-1997 |
| VERIFIED | Yes |
| TOTAL WORKS | 2 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 2 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2022 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 0 |
Evaluation of acute oral toxicity of the Camellia sinensis phytosome formulation in female wistar rats
Acute toxicity study was carried out for evaluation of toxic effect of formulation, safe acute dose for human and potential target organ for toxicity. Tea (Camellia sinensis), a cultivated evergreen plant and belonging to Theaceae family. The goal of present investigation was to perform acute toxicity study of Camellia sinensis phytosome formulation (CSP) for estimation of LD 50 or Median fatal dose and safe acute dose for human. A total of 12 fe…
Molecular docking, synthesis and biological evaluation of some Imidazo-thiadiazole based Chalcone derivatives as potent triple mutant T790M/C797S EGFR inhibitors
In present study, we have designed and developed some imidazo-thiadiazole based chalcone derivatives as potential EGFR inhibitors. The designed derivative were screened through molecular docking studies and subjected for synthesis followed by in vitro anticancer activity. Most interestingly many molecules had formed one Pi-donor hydrogen bond (Pi-sulfur) or conventional hydrogen bond with Cys797 which is mutated amino acid residue for the second …
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Evaluation of acute oral toxicity of the Camellia sinensis phytosome formulation in female wistar rats
Acute toxicity study was carried out for evaluation of toxic effect of formulation, safe acute dose for human and potential target organ for toxicity. Tea (Camellia sinensis), a cultivated evergreen plant and belonging to Theaceae family. The goal of present investigation was to perform acute toxicity study of Camellia sinensis phytosome formulation (CSP) for estimation of LD 50 or Median fatal dose and safe acute dose for human. A total of 12 fe…
Molecular docking, synthesis and biological evaluation of some Imidazo-thiadiazole based Chalcone derivatives as potent triple mutant T790M/C797S EGFR inhibitors
In present study, we have designed and developed some imidazo-thiadiazole based chalcone derivatives as potential EGFR inhibitors. The designed derivative were screened through molecular docking studies and subjected for synthesis followed by in vitro anticancer activity. Most interestingly many molecules had formed one Pi-donor hydrogen bond (Pi-sulfur) or conventional hydrogen bond with Cys797 which is mutated amino acid residue for the second …
Acute toxicity (1 works) · Biochemistry (1 works) · Biology (1 works) · Body weight (1 works) · Botany (1 works) · Camellia sinensis (1 works) · Chalcone (1 works) · Chemistry (1 works) · Combinatorial chemistry (1 works) · Computational Drug Discovery Methods (1 works)