Pravin G Dhone
Biographic Data
| ID | 8420734 |
|---|---|
| NAME | Pravin G Dhone |
| GIVEN NAMES | Pravin G |
| FAMILY NAME | Dhone |
| SIGNATURE | DHONE P G |
| AFFILIATIONS | Ganesh Shankar Vidyarthi Memorial Medical College |
| VERIFIED | No |
| TOTAL WORKS | 30 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 30 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2022 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 0 |
The clinical and histopathological assessment of nasal mass amongst patients in ear, nose, and throat
The nose of the prominent feature of the face and often catches the attention of the face and often catches the attention on the looker whenever it is deformed or altered in shape. Nose is not only important functionally, but automatically and aesthetically as well as. What is pleasing and what is pleasing and what is beautiful is difficult to answer and depends upon the emotional reaction of the be holder. The observations are made from the stud…
To evaluate the safety and efficacy of saroglitazar among pre-diabetes and dyslipidemia
Patients with prediabetes are not only at increased risk of progression to type 2 diabetes, but they are also at high risk of developing cardiovascular (CV) risk compared to normoglycemic people. Further, prediabetes is also often associated with abnormal lipid levels (dyslipidemia). We therefore aimed to evaluate the effect of saroglitazar in patients with prediabetes and dyslipidemia. This was a prospective, single centre, single arm study invo…
The prevalence of dry eye in diabetes mellitus
Dry eye is more prevalent in diabetic patients as indicated by increased use of lubricant than non-diabetic. Dry eye is one of the most common ailments seen by an ophthalmologist, especially in this polluted modern word. Diabetes one of the most common diseases affecting the urban population accounts for significant number of cases of dry eye. The prevalence of dry eye syndrome was 54.3%. Diabetes and dry eyes appear to have a common association …
Cervical tuberculous lymphadenitis
Background: Diagnosis of cervical tuberculous lymphadenitis has been challenging to clinicians as it mimics multiple diseases. USG has upper hand over other diagnostic modalities as it is non- invasive, low cost, time saving and guided procedures like FNAC and core needle biopsy can be performed. Methods: This is a prospective observational study conducted in 100 patients from June 2019 to May 2020 in Dept of Pulmonary medicine, PRM Medical Colle…
A study about the nasal obstruction present in cases of malignancy in ent
Tumours in the nasal cavity and paranasal sinuses were recognized during the time of Hippocrates. Whillis (1948) defined tumours as “an abnormal mass of tissue, the growth of which exceeds and is coordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the Change. From the table I it is evident that only 5 cases of malignant and 3 cases of fungal Granuloma, there was bony er…
Diagnostic presentations of different pleural effusion patients to a tertiary care centre
BACKGROUND-Pleural effusion is defined as collection of fluid between the two pleural covering. OBJECTIVE-To evaluate the different etiologies of pleural effusion according to laboratory report. METHODOLOGY-Data was collected in a nonprobability convenience technique with descriptive cross- sectional study in indoor patient of pulmonary medicine department of Balangir Bhima Bhoi medical college from 2017 nov to 2020 nov,202 patients included in t…
Formulation and evaluation of floating tablet of levofloxacin
Floating drug delivery system is a system to retained the drug in the stomach which is applicable only for poorly soluble and less stable in intestinal fluids. It is basis on the dense on gastric fluids which is float on gastric fluids. Floating tablet Formulations of levofloxacin were prepared by simple blending and punching with carbopol, HPMC K4M, sodium bicarbonate, citric acid and talk for oral application. Levofloxacin is an antibiotic drug…
Observation of role of orthofix limb reconstruction system in with non-union with major soft tissue defect
Soft tissue loss with multiple sinuses, osteomyelitis, osteoporosis, complex deformities with limb length inequality, stiffness of the adjacent joints and multi drug resistant infection all complicate treatment and recovery. Aim of the study is to observe the role of Orthofix limb reconstruction system as a treatment in non-union with bone loss and major soft tissue defect due to fresh fractures. The method of treatment of infected non-union by t…
Utilisation pattern of AMA in surgery department in a tertiary care hospital
In the recent past when people were dying of communicable diseases, the discovery and innovations of AMAs , did a miracle as saved millions of life worldwide, by special toxic and killing effect on infecting microorganisms and not damaging host, thus satisfying own name as MIRACLE MEDICINE or MAGIC BULLETS. Paul Ehlrich of Austria discovered first time chemotherapeutic agent in 1906. Next Domagk of Germany, A. Fleming of England, Walks man of USA…
Analysis of utilization pattern of antimicrobial agents in a tertiary care teaching hospital
Bacteria are being unicellular and prokaryotes came to this earth before us and others. They are able to survive anywhere in this earth including soil, water both saline and normal, in all living creatures, hills, sands, ice of north and south poles, sea and desert. Some are helpful and commensals as they not harm us but many of them produce disease in which they survive, these are harmful bacteria, so called pathogenic or disease producing bacte…
The incidence of maxillary sinus carcinoma in nasal mass
The external nose is pyramidal in shape with its root above and base directed downwards. The framework is composed of bones and cartilages. The bones are the two nasal bones articulating medially. Laterally they articulate with the frontal process of maxilla, superiorly to the medial part of nasal notch of frontal bone and inferiorly to the lateral cartilage of nose and posteriorly with the perpendicular plate of ethmoid bone. Considering the mal…
Comparative study to evaluate safety and efficacy of Metformin versus sitagliptin alone and combination in type 2 diabetes mellitus
Type 2 Diabetes mellitus (Type 2DM) is chronic, lifelong progressive metabolic disease characterized by hyperglycaemia due to absolute or relative insulinopaenia. The metabolic dysregulation that contributes to hyperglycaemia includes diminished insulin secretion, impaired glucose utilization or increased glucose production, and eventually causes pathophysiological changes in multiple organs and organ systems. Our study showed Sitagliptin was sup…
Effect of enoxaparin on d-dimer level and survival in hospitalized Covid-19 patients
Coronavirus disease 2019 (COVID-19), is caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) infection. It is associated with a severe coagulopathy i.e. Venous Thrombo-embolism (VTE), for which optimum strategies ought to be developed for early treatment. D-dimer, a fibrin degradation product is raised in critical COVID-19 pneumonia and increases mortality. Enoxaparin, a low molecular weight heparin, has shown beneficial results …
Analysis of utilization pattern of antimicrobial agents
AMAs – Antimicrobial Agents are commonest used medicaments in all type of health faculty and specialty. To find out rationality of Anti-microbial use in different IPD wards such as ICUs of a tertiary care teaching hospital of eastern Odisha- SCB.MC & Hospital, Cuttack, Odisha. To start with AMAs prescribed empirically in 100% patients, at no response or decreased response, C/S is done in—21% of cases, and AMAs changed later on as per C/S report. …
To investigate the efficacy of topical application of heparin sodium, benzyle nicotinate and nifedipine paste in external thrombosed prolapsed haemorrhoids
Eighty-six patient (49males, 37 females) with acute thrombosed external prolapsed haemorrhoids from January 2019 to January 2022 were treated topically with heparin sodium plus benzyl nicotinate along with 0.5% nifedipine ointment paste (t.i.d.) for 8 wk. All the patients were advised to take a high-fibre diet and assessed post-treatment at 2, 4 and 8 weeks. The healing of external thrombosed haemorrhoids and any side effects were recorded. The p…
Study on primary non-small cell lung cancer with special reference to immunohistochemistry, EGFR mutation and K-RAS mutation in a tertiary care hospital
Background: In lung cancers the use of immunohistochemistry is recommended for those cases in which diagnosis is unclear between adenocarcinoma and squamous cell carcinoma. This study is to know the different mutations in NSCLC of the lungs in our tertiary care centre. Aims & Objectives: To study clinical and radiological correlation with different histological types of primary lung cancer with refence to immunohistochemistry TTF-1 and p63 and to…
The level of incidence of rhinosporidiosis in nasal mass in ear, nose and throat
According to Swindle (1935) in the mucous membrane of the nose the arrangement of the blood vessels consists of a superficial venous plexus and a deeper arteriolar. System, arranged parallel to the long axis of the nose. The relationship of taking bath in infected pond and agriculture work is explained by the above observation. There is no specific occupational incidence in other of nasal mass in the present series. Out of 8 cases (6.15%) of mali…
In vivo antipyretic activity of Scutia myrtina acute oral toxicity study
Pyrexia or Fever is defined as an elevation of body temperature. It is a response due to tissue damage, inflammation, malignancy or graft rejection. Cytokines, interleukin, interferon and Tumor Necrosis Factor α (TNF- α) are formed in large amount under this condition, which increase PGE2 which in turn triggers hypothalamus to elevate body temperature. The present investigation it may be concluded that the hydroalcoholic extract of leaves of Scut…
Pre-clinical prediction of coronary atherosclerosis in copd by carotid artery intima media thickness
Aim and Introduction: To determine the association between Coronary atherosclerosis in Chronic Obstructive Pulmonary Disease and Carotid Artery Intima Media Thickness. The objective of the present case control study is to determine the association between carotid atherosclerosis in COPD patients and cardiovascular morbidity. Material and methods. It was a prospective case-control observational study. 50 COPD patients and 50 age- and gender-matche…
Different comparison of mean SR. homocystene in serum 25 – hydroxyvitamin D in acute stroke
The active form of vitamin D is 1,25 dihydroxy vitamin D. Renal and many extra renal tissues are able to synthesize 1,25 dihydroxy vitamin D on a local and intracellular level. Local tissue level of 1,25 di-hydroxyvitamin D is determined by concentration of circulating 25(OH) vitamin D level. Stroke is a common worldwide health problem. It is a major cause of morbidity, mortality and disability in developed as well as developing countries. Both v…
Anatomical variation of frequency and intensity of symptoms in patients nose with chronic rhinosinusitis
Chronic rhinosinusitis is one of the most frequent chronic disorders which influences the patient’s quality of life significantly. The objective of this paper was to examine which are the most frequent and intensive symptoms in patients with chronic rhinosinusitis. The study done in 80 patients with clinical diagnosis of chronic rhinosinusitis that was endoscopically proven and computer tomography of the nose and paranasal sinuses. All the possib…
Comparative study to evaluate the efficacy and safety of Pioglitazone and Metformin on Homa IR and HbA1c in patient of prediabetes
In India, the number of people with diabetes is increasing day-by-day. Due to a sole “Asian Indian Phenotype,” Indians develop diabetes an era earlier and have an earlier onset of complications. Hence, it is essential to evaluate earlier stage of disease progression. Prediabetes, typically defined as blood glucose levels above normal but below the thresholds of diagnosis of diabetes, is a risk state that defines a high chance of developing diabet…
Observation of various symptoms of non-neoplastic nasal mass in ent
Tumors in the nasal cavity and paranasal sinuses were recognized during the time of Hippocrates. Whillis (1948) defined tumors as “an abnormal mass of tissue, the growth of which exceeds and is coordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the Change” From the table I it is evident that only 5 cases of malignant and 3 cases of fungal Granuloma, there was bony eros…
The correlation of dry eye with Glycemic Control (HBa1 level)
Diabetes mellitus can lead to various ocular complications such as diabetic retinopathy (DR), cataract, glaucoma, keratopathy, refractive changes, palsy of the oculomotor nerve, and chronic inflammation of lids. Diabetes mellitus a common microangiopathy not only involve the inner structures of eye but also affect cornea and ocular adnexa. After 6 months of follow up 33 patients who were not on strict glycaemic control and had bad compliance with…
The clinical-pathological evaluation of dry eye in dibetes mellitus
Histopathologic ally in patient with diabetes the basement membrane is fragile in cornea which leads to recurrent corneal erosion. it was observed that reflex tearing was decreased & associated ocular surface diseases leads to a state of dryness in eye with diabetic patient. There is a close relationship between diabetic retinopathy and Kerato conjunctivitis Sicca (P< 0.006) with no laser Rx in diabetic eye in comparison to laser treatment. The p…
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The clinical and histopathological assessment of nasal mass amongst patients in ear, nose, and throat
The nose of the prominent feature of the face and often catches the attention of the face and often catches the attention on the looker whenever it is deformed or altered in shape. Nose is not only important functionally, but automatically and aesthetically as well as. What is pleasing and what is pleasing and what is beautiful is difficult to answer and depends upon the emotional reaction of the be holder. The observations are made from the stud…
To evaluate the safety and efficacy of saroglitazar among pre-diabetes and dyslipidemia
Patients with prediabetes are not only at increased risk of progression to type 2 diabetes, but they are also at high risk of developing cardiovascular (CV) risk compared to normoglycemic people. Further, prediabetes is also often associated with abnormal lipid levels (dyslipidemia). We therefore aimed to evaluate the effect of saroglitazar in patients with prediabetes and dyslipidemia. This was a prospective, single centre, single arm study invo…
The prevalence of dry eye in diabetes mellitus
Dry eye is more prevalent in diabetic patients as indicated by increased use of lubricant than non-diabetic. Dry eye is one of the most common ailments seen by an ophthalmologist, especially in this polluted modern word. Diabetes one of the most common diseases affecting the urban population accounts for significant number of cases of dry eye. The prevalence of dry eye syndrome was 54.3%. Diabetes and dry eyes appear to have a common association …
Cervical tuberculous lymphadenitis
Background: Diagnosis of cervical tuberculous lymphadenitis has been challenging to clinicians as it mimics multiple diseases. USG has upper hand over other diagnostic modalities as it is non- invasive, low cost, time saving and guided procedures like FNAC and core needle biopsy can be performed. Methods: This is a prospective observational study conducted in 100 patients from June 2019 to May 2020 in Dept of Pulmonary medicine, PRM Medical Colle…
A study about the nasal obstruction present in cases of malignancy in ent
Tumours in the nasal cavity and paranasal sinuses were recognized during the time of Hippocrates. Whillis (1948) defined tumours as “an abnormal mass of tissue, the growth of which exceeds and is coordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the Change. From the table I it is evident that only 5 cases of malignant and 3 cases of fungal Granuloma, there was bony er…
Diagnostic presentations of different pleural effusion patients to a tertiary care centre
BACKGROUND-Pleural effusion is defined as collection of fluid between the two pleural covering. OBJECTIVE-To evaluate the different etiologies of pleural effusion according to laboratory report. METHODOLOGY-Data was collected in a nonprobability convenience technique with descriptive cross- sectional study in indoor patient of pulmonary medicine department of Balangir Bhima Bhoi medical college from 2017 nov to 2020 nov,202 patients included in t…
Formulation and evaluation of floating tablet of levofloxacin
Floating drug delivery system is a system to retained the drug in the stomach which is applicable only for poorly soluble and less stable in intestinal fluids. It is basis on the dense on gastric fluids which is float on gastric fluids. Floating tablet Formulations of levofloxacin were prepared by simple blending and punching with carbopol, HPMC K4M, sodium bicarbonate, citric acid and talk for oral application. Levofloxacin is an antibiotic drug…
Observation of role of orthofix limb reconstruction system in with non-union with major soft tissue defect
Soft tissue loss with multiple sinuses, osteomyelitis, osteoporosis, complex deformities with limb length inequality, stiffness of the adjacent joints and multi drug resistant infection all complicate treatment and recovery. Aim of the study is to observe the role of Orthofix limb reconstruction system as a treatment in non-union with bone loss and major soft tissue defect due to fresh fractures. The method of treatment of infected non-union by t…
Utilisation pattern of AMA in surgery department in a tertiary care hospital
In the recent past when people were dying of communicable diseases, the discovery and innovations of AMAs , did a miracle as saved millions of life worldwide, by special toxic and killing effect on infecting microorganisms and not damaging host, thus satisfying own name as MIRACLE MEDICINE or MAGIC BULLETS. Paul Ehlrich of Austria discovered first time chemotherapeutic agent in 1906. Next Domagk of Germany, A. Fleming of England, Walks man of USA…
Analysis of utilization pattern of antimicrobial agents in a tertiary care teaching hospital
Bacteria are being unicellular and prokaryotes came to this earth before us and others. They are able to survive anywhere in this earth including soil, water both saline and normal, in all living creatures, hills, sands, ice of north and south poles, sea and desert. Some are helpful and commensals as they not harm us but many of them produce disease in which they survive, these are harmful bacteria, so called pathogenic or disease producing bacte…
The incidence of maxillary sinus carcinoma in nasal mass
The external nose is pyramidal in shape with its root above and base directed downwards. The framework is composed of bones and cartilages. The bones are the two nasal bones articulating medially. Laterally they articulate with the frontal process of maxilla, superiorly to the medial part of nasal notch of frontal bone and inferiorly to the lateral cartilage of nose and posteriorly with the perpendicular plate of ethmoid bone. Considering the mal…
Comparative study to evaluate safety and efficacy of Metformin versus sitagliptin alone and combination in type 2 diabetes mellitus
Type 2 Diabetes mellitus (Type 2DM) is chronic, lifelong progressive metabolic disease characterized by hyperglycaemia due to absolute or relative insulinopaenia. The metabolic dysregulation that contributes to hyperglycaemia includes diminished insulin secretion, impaired glucose utilization or increased glucose production, and eventually causes pathophysiological changes in multiple organs and organ systems. Our study showed Sitagliptin was sup…
Effect of enoxaparin on d-dimer level and survival in hospitalized Covid-19 patients
Coronavirus disease 2019 (COVID-19), is caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) infection. It is associated with a severe coagulopathy i.e. Venous Thrombo-embolism (VTE), for which optimum strategies ought to be developed for early treatment. D-dimer, a fibrin degradation product is raised in critical COVID-19 pneumonia and increases mortality. Enoxaparin, a low molecular weight heparin, has shown beneficial results …
Analysis of utilization pattern of antimicrobial agents
AMAs – Antimicrobial Agents are commonest used medicaments in all type of health faculty and specialty. To find out rationality of Anti-microbial use in different IPD wards such as ICUs of a tertiary care teaching hospital of eastern Odisha- SCB.MC & Hospital, Cuttack, Odisha. To start with AMAs prescribed empirically in 100% patients, at no response or decreased response, C/S is done in—21% of cases, and AMAs changed later on as per C/S report. …
To investigate the efficacy of topical application of heparin sodium, benzyle nicotinate and nifedipine paste in external thrombosed prolapsed haemorrhoids
Eighty-six patient (49males, 37 females) with acute thrombosed external prolapsed haemorrhoids from January 2019 to January 2022 were treated topically with heparin sodium plus benzyl nicotinate along with 0.5% nifedipine ointment paste (t.i.d.) for 8 wk. All the patients were advised to take a high-fibre diet and assessed post-treatment at 2, 4 and 8 weeks. The healing of external thrombosed haemorrhoids and any side effects were recorded. The p…
Study on primary non-small cell lung cancer with special reference to immunohistochemistry, EGFR mutation and K-RAS mutation in a tertiary care hospital
Background: In lung cancers the use of immunohistochemistry is recommended for those cases in which diagnosis is unclear between adenocarcinoma and squamous cell carcinoma. This study is to know the different mutations in NSCLC of the lungs in our tertiary care centre. Aims & Objectives: To study clinical and radiological correlation with different histological types of primary lung cancer with refence to immunohistochemistry TTF-1 and p63 and to…
The level of incidence of rhinosporidiosis in nasal mass in ear, nose and throat
According to Swindle (1935) in the mucous membrane of the nose the arrangement of the blood vessels consists of a superficial venous plexus and a deeper arteriolar. System, arranged parallel to the long axis of the nose. The relationship of taking bath in infected pond and agriculture work is explained by the above observation. There is no specific occupational incidence in other of nasal mass in the present series. Out of 8 cases (6.15%) of mali…
In vivo antipyretic activity of Scutia myrtina acute oral toxicity study
Pyrexia or Fever is defined as an elevation of body temperature. It is a response due to tissue damage, inflammation, malignancy or graft rejection. Cytokines, interleukin, interferon and Tumor Necrosis Factor α (TNF- α) are formed in large amount under this condition, which increase PGE2 which in turn triggers hypothalamus to elevate body temperature. The present investigation it may be concluded that the hydroalcoholic extract of leaves of Scut…
Pre-clinical prediction of coronary atherosclerosis in copd by carotid artery intima media thickness
Aim and Introduction: To determine the association between Coronary atherosclerosis in Chronic Obstructive Pulmonary Disease and Carotid Artery Intima Media Thickness. The objective of the present case control study is to determine the association between carotid atherosclerosis in COPD patients and cardiovascular morbidity. Material and methods. It was a prospective case-control observational study. 50 COPD patients and 50 age- and gender-matche…
Different comparison of mean SR. homocystene in serum 25 – hydroxyvitamin D in acute stroke
The active form of vitamin D is 1,25 dihydroxy vitamin D. Renal and many extra renal tissues are able to synthesize 1,25 dihydroxy vitamin D on a local and intracellular level. Local tissue level of 1,25 di-hydroxyvitamin D is determined by concentration of circulating 25(OH) vitamin D level. Stroke is a common worldwide health problem. It is a major cause of morbidity, mortality and disability in developed as well as developing countries. Both v…
Anatomical variation of frequency and intensity of symptoms in patients nose with chronic rhinosinusitis
Chronic rhinosinusitis is one of the most frequent chronic disorders which influences the patient’s quality of life significantly. The objective of this paper was to examine which are the most frequent and intensive symptoms in patients with chronic rhinosinusitis. The study done in 80 patients with clinical diagnosis of chronic rhinosinusitis that was endoscopically proven and computer tomography of the nose and paranasal sinuses. All the possib…
Comparative study to evaluate the efficacy and safety of Pioglitazone and Metformin on Homa IR and HbA1c in patient of prediabetes
In India, the number of people with diabetes is increasing day-by-day. Due to a sole “Asian Indian Phenotype,” Indians develop diabetes an era earlier and have an earlier onset of complications. Hence, it is essential to evaluate earlier stage of disease progression. Prediabetes, typically defined as blood glucose levels above normal but below the thresholds of diagnosis of diabetes, is a risk state that defines a high chance of developing diabet…
Observation of various symptoms of non-neoplastic nasal mass in ent
Tumors in the nasal cavity and paranasal sinuses were recognized during the time of Hippocrates. Whillis (1948) defined tumors as “an abnormal mass of tissue, the growth of which exceeds and is coordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the Change” From the table I it is evident that only 5 cases of malignant and 3 cases of fungal Granuloma, there was bony eros…
The correlation of dry eye with Glycemic Control (HBa1 level)
Diabetes mellitus can lead to various ocular complications such as diabetic retinopathy (DR), cataract, glaucoma, keratopathy, refractive changes, palsy of the oculomotor nerve, and chronic inflammation of lids. Diabetes mellitus a common microangiopathy not only involve the inner structures of eye but also affect cornea and ocular adnexa. After 6 months of follow up 33 patients who were not on strict glycaemic control and had bad compliance with…
The clinical-pathological evaluation of dry eye in dibetes mellitus
Histopathologic ally in patient with diabetes the basement membrane is fragile in cornea which leads to recurrent corneal erosion. it was observed that reflex tearing was decreased & associated ocular surface diseases leads to a state of dryness in eye with diabetic patient. There is a close relationship between diabetic retinopathy and Kerato conjunctivitis Sicca (P< 0.006) with no laser Rx in diabetic eye in comparison to laser treatment. The p…
Medicine (30 works) · Internal Medicine (16 works) · Surgery (10 works) · Endocrinology (9 works) · Pathology (9 works) · Diabetes mellitus (8 works) · Advanced Glycation End Products research (4 works) · Anatomy (4 works) · Biology (4 works) · Disease (4 works)