Abigail W Bigham
Biographic Data
| ID | 88339 |
|---|---|
| NAME | Abigail W Bigham |
| GIVEN NAMES | Abigail W |
| FAMILY NAME | Bigham |
| SIGNATURE | BIGHAM A W |
| AFFILIATIONS | University of Michigan |
| ORCID | 0000-0002-0109-5844 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 12 |
| AUTHOR COUNT | 8 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 2 |
Embodiment of sociopolitical stress during pregnancy and coping strategies among perinatal Filipina women
Fear and uncertainty surrounding contemporary sociopolitical environments are emerging as global concerns for maternal and fetal health. However, limited research has examined how pregnant individuals perceive and embody these conditions and their implications for health. We focus on the Philippines, a country marked by intense State violence, to explore how fraught sociopolitical environments shape the impacts of stress during pregnancy among Fi…
Advances in Understanding Adaptive Hemoglobin Concentration at High Altitude
Today, more than 81 million people globally live at altitudes ≥ 2,500 m (Tremblay and Ainslie 2021), which corresponds to less than 73% of the oxygen present at sea level, dropping exponentially downwards with increasing elevation. This reduced atmospheric oxygen content, known as high-altitude hypoxia, presents a pronounced physiological challenge to human health, well-being, and reproduction. Nevertheless, there are three global regions where h…
Larger spleens and greater splenic contraction during exercise may be an adaptive characteristic of Nepali Sherpa at high‐altitude
Objectives The Sherpa ethnic group living at altitude in Nepal may have experienced natural selection in response to chronic hypoxia. We have previously shown that Sherpa in Kathmandu (1400 m) possess larger spleens and a greater apnea‐induced splenic contraction compared to lowland Nepalis. This may be significant for exercise capacity at altitude as the human spleen responds to stress‐induced catecholamine secretion by an immediate contraction,…
Exhaled nitric oxide in ethnically diverse high‐altitude native populations: A comparative study
OBJECTIVES: Andean and Tibetan high-altitude natives exhibit a high concentration of nitric oxide (NO) in the lungs, suggesting that NO plays an adaptive role in offsetting hypobaric hypoxia. We examined the exhaled NO concentration as well as partial pressure of several additional high-altitude native populations in order to examine the possibility that this putative adaptive trait, that is, high exhaled NO, is universal. METHODS: We recruited t…
The Genetic Anthropologist's Contribution to Understanding Race and Racial Health Disparities
The Genetic Anthropologist’s Contribution to Understanding Race and Racial Health Disparities Abigail W. Bigham and Amy Non The study of “race” has a deep and contentious history within biological anthropology, where it was once the central theoretical concept of the field (Caspari 2003). Building off of typological models of human variation put forth by scholars such as Johann Friedrich Blumenbach and Samuel George Morton, essentialist ideas abo…
Andean and Tibetan patterns of adaptation to high altitude
OBJECTIVES: High-altitude hypoxia, or decreased oxygen levels caused by low barometric pressure, challenges the ability of humans to live and reproduce. Despite these challenges, human populations have lived on the Andean Altiplano and the Tibetan Plateau for millennia and exhibit unique circulatory, respiratory, and hematological adaptations to life at high altitude. We and others have identified natural selection candidate genes and gene region…
Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua
High altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors (genetic/developmental) that influence lung volumes provides insight into the adaptive responses of highlanders. In order to test for the effect of growth and development at high altitude on lung volumes, we obtained forced vital ca…
"So mortal and so strange a pang": A tribute to Paul T. Baker
"So mortal and so strange a pang": A tribute to Paul T. Baker
Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua
High altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors (genetic/developmental) that influence lung volumes provides insight into the adaptive responses of highlanders. In order to test for the effect of growth and development at high altitude on lung volumes, we obtained forced vital ca…
The Genetic Anthropologist's Contribution to Understanding Race and Racial Health Disparities
The Genetic Anthropologist’s Contribution to Understanding Race and Racial Health Disparities Abigail W. Bigham and Amy Non The study of “race” has a deep and contentious history within biological anthropology, where it was once the central theoretical concept of the field (Caspari 2003). Building off of typological models of human variation put forth by scholars such as Johann Friedrich Blumenbach and Samuel George Morton, essentialist ideas abo…
"So mortal and so strange a pang": A tribute to Paul T. Baker
Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua
High altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors (genetic/developmental) that influence lung volumes provides insight into the adaptive responses of highlanders. In order to test for the effect of growth and development at high altitude on lung volumes, we obtained forced vital ca…
Andean and Tibetan patterns of adaptation to high altitude
OBJECTIVES: High-altitude hypoxia, or decreased oxygen levels caused by low barometric pressure, challenges the ability of humans to live and reproduce. Despite these challenges, human populations have lived on the Andean Altiplano and the Tibetan Plateau for millennia and exhibit unique circulatory, respiratory, and hematological adaptations to life at high altitude. We and others have identified natural selection candidate genes and gene region…
The Genetic Anthropologist's Contribution to Understanding Race and Racial Health Disparities
The Genetic Anthropologist’s Contribution to Understanding Race and Racial Health Disparities Abigail W. Bigham and Amy Non The study of “race” has a deep and contentious history within biological anthropology, where it was once the central theoretical concept of the field (Caspari 2003). Building off of typological models of human variation put forth by scholars such as Johann Friedrich Blumenbach and Samuel George Morton, essentialist ideas abo…
Exhaled nitric oxide in ethnically diverse high‐altitude native populations: A comparative study
OBJECTIVES: Andean and Tibetan high-altitude natives exhibit a high concentration of nitric oxide (NO) in the lungs, suggesting that NO plays an adaptive role in offsetting hypobaric hypoxia. We examined the exhaled NO concentration as well as partial pressure of several additional high-altitude native populations in order to examine the possibility that this putative adaptive trait, that is, high exhaled NO, is universal. METHODS: We recruited t…
Larger spleens and greater splenic contraction during exercise may be an adaptive characteristic of Nepali Sherpa at high‐altitude
Objectives The Sherpa ethnic group living at altitude in Nepal may have experienced natural selection in response to chronic hypoxia. We have previously shown that Sherpa in Kathmandu (1400 m) possess larger spleens and a greater apnea‐induced splenic contraction compared to lowland Nepalis. This may be significant for exercise capacity at altitude as the human spleen responds to stress‐induced catecholamine secretion by an immediate contraction,…
Advances in Understanding Adaptive Hemoglobin Concentration at High Altitude
Today, more than 81 million people globally live at altitudes ≥ 2,500 m (Tremblay and Ainslie 2021), which corresponds to less than 73% of the oxygen present at sea level, dropping exponentially downwards with increasing elevation. This reduced atmospheric oxygen content, known as high-altitude hypoxia, presents a pronounced physiological challenge to human health, well-being, and reproduction. Nevertheless, there are three global regions where h…
Embodiment of sociopolitical stress during pregnancy and coping strategies among perinatal Filipina women
Fear and uncertainty surrounding contemporary sociopolitical environments are emerging as global concerns for maternal and fetal health. However, limited research has examined how pregnant individuals perceive and embody these conditions and their implications for health. We focus on the Philippines, a country marked by intense State violence, to explore how fraught sociopolitical environments shape the impacts of stress during pregnancy among Fi…
Effects of high altitude on humans (5 works) · High Altitude and Hypoxia (5 works) · Neuroscience of respiration and sleep (5 works) · Anatomy (3 works) · Biology (3 works) · Internal Medicine (3 works) · Medicine (3 works) · Altitude (triangle) (2 works) · Demography (2 works) · Genetics (2 works)