Wim Degrave
Biographic Data
| ID | 885144 |
|---|---|
| NAME | Wim Degrave |
| GIVEN NAMES | Wim |
| FAMILY NAME | Degrave |
| SIGNATURE | DEGRAVE W |
| AFFILIATIONS | Fundação Oswaldo Cruz |
| ORCID | 0000-0003-3533-4580 |
| VERIFIED | Yes |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2006 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
O papel das plataformas tecnológicas no Brasil como estratégia para preparação e resposta a pandemias
A pandemia de covid-19 evidenciou a necessidade de infraestruturas laboratoriais e tecnologias robustas e integradas para oferecer respostas rápidas a emergências sanitárias. As plataformas tecnológicas, ou core facilities, centralizam equipamentos caros e sofisticados e contam com equipes altamente qualificadas. Durante a pandemia, desempenharam papel essencial no desenvolvimento e no aprimoramento de diagnóstico molecular, análise genômica e su…
The role of technology platforms in Brazil as a strategy for pandemic preparedness and response
The COVID-19 pandemic highlighted the need for robust and integrated laboratory infrastructures and technologies to offer rapid responses to health emergencies. Technology platforms, or core facilities, centralize expensive and sophisticated equipment and rely on teams with high technical expertise. They played, during the pandemic, an essential role in the development and improvement of molecular diagnosis, genomic analysis, support for epidemio…
Transmission dynamics of Sars-CoV-2 variants in the Brazilian state of Pará
Introduction After three years since the beginning of the pandemic, the new coronavirus continues to raise several questions regarding its infectious process and host response. Several mutations occurred in different regions of the SARS-CoV-2 genome, such as in the spike gene, causing the emergence of variants of concern and interest (VOCs and VOIs), of which some present higher transmissibility and virulence, especially among patients with previ…
Bioinformatics and Health
Ever increasing datasets, new frontiers in science, the development of new approaches for data analysis and representation, and the tackling of new, complex questions, those are the main driving forces for bioinformatics.The availability of faster and more powerful hardware tools and the further developing field of computer sciences are one of the main underlying supporting forces
Bioinformática e Saúde
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil
A plataforma PDTIS de bioinformática
Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many research institutions organized a bioinformatics core facility. In this work, we describe typical bioinformatics activities and the organization of a bioinformatics core with institutional support…
Comparando genomas
organismos, entre estes, procariotos, leveduras, protozorios, plantas, invertebrados e vertebrados, incluindo o prprio Homo sapiens
The PDTIS Bioinformatics Platform
Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many research institutions organized a bioinformatics core facility. In this work, we describe typical bioinformatics activities and the organization of a bioinformatics core with institutional support…
Ellipsoid clustering machine
This study presents a new machine learning strategy to address the disease diagnosis classification problem that comprises an unknown number of disease classes. This is exemplified by a software called Ellipsoid Clustering Machine (ECM) that identifies conserved regions in mass spectrometry proteomic profiles obtained from control subjects and uses these to estimate classification boundaries based on sample variance. The software can also be used…
Comparing Genomes
Since the 1990's, the complete genetic code of more than 600 living organisms has been deciphered, such as bacteria, yeasts, protozoan parasites, invertebrates and vertebrates, including Homo sapiens, and plants. More than 2,000 other genome projects representing medical, commercial, environmental and industrial interests, or comprising model organisms, important for the development of the scientific research, are currently in progress. The achie…
Máquina de agrupamento por elipsóide
Universidade Federal do Rio de Janeiro. Programa de Engenharia de Sistemas e Computação. Rio de Janeiro, RJ, Brasil
Qualificação e Percepção de Riscos de Trabalhadores
Este estudo analisa alguns elementos relativos à formação e capacitação de trabalhadores que atuam na área biotecnológica. Buscou-se perceber a relação entre o conhecimento acerca de biossegurança e a percepção sobre os riscos envolvidos nos diferentes processos de trabalho. Para tanto, foram realizadas entrevistas, baseadas em um roteiro previamente definido, em uma empresa privada e uma instituição pública. Das conclusões emerge uma série de si…
No prominent works on this page.
Qualificação e Percepção de Riscos de Trabalhadores
Este estudo analisa alguns elementos relativos à formação e capacitação de trabalhadores que atuam na área biotecnológica. Buscou-se perceber a relação entre o conhecimento acerca de biossegurança e a percepção sobre os riscos envolvidos nos diferentes processos de trabalho. Para tanto, foram realizadas entrevistas, baseadas em um roteiro previamente definido, em uma empresa privada e uma instituição pública. Das conclusões emerge uma série de si…
Bioinformatics and Health
Ever increasing datasets, new frontiers in science, the development of new approaches for data analysis and representation, and the tackling of new, complex questions, those are the main driving forces for bioinformatics.The availability of faster and more powerful hardware tools and the further developing field of computer sciences are one of the main underlying supporting forces
Bioinformática e Saúde
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil
A plataforma PDTIS de bioinformática
Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many research institutions organized a bioinformatics core facility. In this work, we describe typical bioinformatics activities and the organization of a bioinformatics core with institutional support…
Comparando genomas
organismos, entre estes, procariotos, leveduras, protozorios, plantas, invertebrados e vertebrados, incluindo o prprio Homo sapiens
The PDTIS Bioinformatics Platform
Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many research institutions organized a bioinformatics core facility. In this work, we describe typical bioinformatics activities and the organization of a bioinformatics core with institutional support…
Ellipsoid clustering machine
This study presents a new machine learning strategy to address the disease diagnosis classification problem that comprises an unknown number of disease classes. This is exemplified by a software called Ellipsoid Clustering Machine (ECM) that identifies conserved regions in mass spectrometry proteomic profiles obtained from control subjects and uses these to estimate classification boundaries based on sample variance. The software can also be used…
Comparing Genomes
Since the 1990's, the complete genetic code of more than 600 living organisms has been deciphered, such as bacteria, yeasts, protozoan parasites, invertebrates and vertebrates, including Homo sapiens, and plants. More than 2,000 other genome projects representing medical, commercial, environmental and industrial interests, or comprising model organisms, important for the development of the scientific research, are currently in progress. The achie…
Máquina de agrupamento por elipsóide
Universidade Federal do Rio de Janeiro. Programa de Engenharia de Sistemas e Computação. Rio de Janeiro, RJ, Brasil
Transmission dynamics of Sars-CoV-2 variants in the Brazilian state of Pará
Introduction After three years since the beginning of the pandemic, the new coronavirus continues to raise several questions regarding its infectious process and host response. Several mutations occurred in different regions of the SARS-CoV-2 genome, such as in the spike gene, causing the emergence of variants of concern and interest (VOCs and VOIs), of which some present higher transmissibility and virulence, especially among patients with previ…
O papel das plataformas tecnológicas no Brasil como estratégia para preparação e resposta a pandemias
A pandemia de covid-19 evidenciou a necessidade de infraestruturas laboratoriais e tecnologias robustas e integradas para oferecer respostas rápidas a emergências sanitárias. As plataformas tecnológicas, ou core facilities, centralizam equipamentos caros e sofisticados e contam com equipes altamente qualificadas. Durante a pandemia, desempenharam papel essencial no desenvolvimento e no aprimoramento de diagnóstico molecular, análise genômica e su…
The role of technology platforms in Brazil as a strategy for pandemic preparedness and response
The COVID-19 pandemic highlighted the need for robust and integrated laboratory infrastructures and technologies to offer rapid responses to health emergencies. Technology platforms, or core facilities, centralize expensive and sophisticated equipment and rely on teams with high technical expertise. They played, during the pandemic, an essential role in the development and improvement of molecular diagnosis, genomic analysis, support for epidemio…
Genetics, Bioinformatics, and Biomedical Research (6 works) · Biology (5 works) · Computer Science (5 works) · Biotechnology and Related Fields (4 works) · Computational biology (3 works) · Data science (3 works) · Genomics and Phylogenetic Studies (3 works) · Medicine (3 works) · Philosophy (3 works) · SARS-CoV-2 detection and testing (3 works)