Christian R Abee
Biographic Data
| ID | 8906102 |
|---|---|
| NAME | Christian R Abee |
| GIVEN NAMES | Christian R |
| FAMILY NAME | Abee |
| SIGNATURE | ABEE C R |
| AFFILIATIONS | University of South Alabama |
| ORCID | 0000-0002-5459-3732 |
| VERIFIED | Yes |
| TOTAL WORKS | 17 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 17 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1984 |
| LATEST PUBLICATION YEAR | 2020 |
| H-INDEX | 0 |
Neonatal activity and state control differences among three squirrel monkey subspecies ( Saimiri sciureus sciureus, S. boliviensis boliviensis , and S. boliviensis peruviensis )
Squirrel monkeys are a long‐standing biomedical model, with multiple species and subspecies housed in research facilities. Few studies have examined the developmental differences between these subspecies, which may affect research outcomes. The primate neonatal neurobehavioral assessment was completed at 2 weeks of age with 279 dam‐reared squirrel monkeys (188 Saimiri boliviensis boliviensis , 45 S. b. peruviensis , and 46 Saimiri. sciureus sciur…
Midcycle and luteal elevations of follicle stimulating hormone in squirrel monkeys (Saimiri boliviensis) during the estrous cycle
Follicle stimulating hormone (FSH) has fundamental importance in reproductive function, but its cyclic pattern has not previously been described in the squirrel monkey, due primarily to the lack of a suitable assay. An homologous radioimmunoassay (RIA) based on recombinant cynomolgus FSH measured changes in serum FSH relative to patterns of bioactive luteinizing hormone (LH), estradiol, and progesterone during the estrous cycle. FSH was observed …
Midcycle and luteal elevations of follicle stimulating hormone in squirrel monkeys (Saimiri boliviensis) during the estrous cycle
Follicle stimulating hormone (FSH) has fundamental importance in reproductive function, but its cyclic pattern has not previously been described in the squirrel monkey, due primarily to the lack of a suitable assay. An homologous radioimmunoassay (RIA) based on recombinant cynomolgus FSH measured changes in serum FSH relative to patterns of bioactive luteinizing hormone (LH), estradiol, and progesterone during the estrous cycle. FSH was observed …
Elevated ovarian expression and serum concentration of α inhibin in the luteal phase during follicular development in the squirrel monkey (Saimiri boliviensis) compared to the human
The goal of the present investigation was to determine in the squirrel monkey the source and pattern of inhibin, a hormone known to effect reproductive steroid levels via pituitary and ovarian mechanisms. Since this seasonally polyestrous species is known to have elevated serum levels of reproductive steroids compared to other primates, the levels of ovarian alpha subunit mRNA expression and serum total alpha inhibin, estradiol, progesterone, and…
Age‐related hormonal differences in cycling squirrel monkeys ( Saimiri boliviensis boliviensis )
This study was planned to evaluate the poor reproductive performance of aged squirrel monkeys in a self‐sustaining breeding colony. Two groups of monkeys aged 6–8 years (Group 1), and >12 years (Group 2) were evaluated. During the midbreeding season, daily blood samples were obtained for a period of 35 days from 10 animals in each group. Blood samples were assayed for serum estradiol (E), progesterone (P), and bioassayable luteinizing hormone (bi…
Allomaternal interactions in the Bolivian squirrel monkey ( Saimiri boliviensis boliviensis )
Allomaternal behavior is defined as maternal‐like interactions between an infant and some animal other than its natural mother. The occurrence of allomothering can have a profound influence on the life of the infant and on the animal with which the infant interacts. Allomaternal interactions were studied during the first 6 months of life in 50 Bolivian squirrel monkeys in two different social settings. Allomaternal interactions began during the f…
Characterization of prolactin and growth hormone immuno‐ and bioactivities in the pituitary gland and serum of the squirrel monkey (Saimiri boliviensis boliviensis)
The immunological and biological activities of growth hormone (GH) and prolactin (PRL) in the pituitary gland and serum of the squirrel monkey ( Saimiri boliviensis boliviensis ) have been studied. Proteins in pituitary homogenates were solubilized in 1% SDS, electrophoresed on 12% polyacrylamide gels, and transferred to nitrocellulose. Squirrel monkey GH and PRL were identified by immunoblotting with anti‐human GH antibodies and a monoclonal ant…
Confirmation of ovulation and characterization of luteinizing hormone and progesterone secretory patterns in cycling, isosexually housed Bolivian squirrel monkeys ( Saimiri boliviensis boliviensis )
In the female Bolivian squirrel monkey a much greater elevation of serum estradiol (E 2 ) was measured after mating than that observed in similary cycling monkeys that did not mate. This raised the possibility that cycling squirrel monkeys may not ovulate during nonmated cycles To test this hypothesis, we performed laparoscopies on nine isosexually housed, cycling monkeys to observe the ovaries after the luteinizing hormone (LH) surge, which was …
Genetic relationships among three squirrel monkey types
Fourteen electrophoretically variable and 12 monomorphic erythrocytic and serum proteins were used to determine the genetic relationships among Bolivian squirrel monkeys ( Saimiri boliviensis boliviensis ), Peruvian squirrel monkeys ( Saimiri boliviensis peruviensis ), and Guyanese squirrel monkeys ( Saimiri sciureus sciureus ). The results supported the classification scheme of Hershkovitz ( AMERICAN JOURNAL OF PRIMATOLOGY 7:155–210, 1984), whic…
Determination of lactogenic activity in the serum of the squirrel monkey ( Saimiri boliviensis ) using the Nb2 lymphoma bioassay
Determination of squirrel monkey prolactin by immunoassay has been hampered by the lack of antiserum specific to prolactin from this species. As an alternate method, we have investigated whether the Nb2 lymphoma bioassay could be adapted for routine measurement of the lactogenic activity of samples of squirrel monkey serum. The growth of the Nb2 cells is absolutely dependent on the presence of lactogens in the culture medium. The cells were maint…
Forthcoming article
Seasonal changes in serum dehydroepiandrosterone, androstenedione, and testosterone levels in the squirrel monkey ( Saimiri boliviensis boliviensis )
The squirrel monkey ( Saimiri boliviensis boliviensis ) has a well‐defined breeding season during which adult males undergo androgen‐dependent morphological changes, with acquisition of active spermatogenesis. To assess the hormonal events of this annual cycle, blood samples were obtained weekly from ten adult males, and serum was assayed for testosterone (T), androstenedione (ΔA), and dehydroepiandrosterone (DHEA). A significant seasonal variati…
Enteric trichomonads of squirrel monkeys ( Saimiri sp)
In a large breeding colony of squirrel monkeys, a previous study demonstrated apparent universal infestation of adult animals with enteric trichomonads. The potential of these organisms to act as a source of experimental variability and the potential pathogenic effects of parasitism in this species stimulated this study of organism acquisition and treatment. Age of natural infestation with trichomonads was determined from results of microscopic e…
In vitro bioactive luteinizing hormone assay shows cyclical, seasonal hormonal changes and response to luteinizing‐hormone releasing hormone in the squirrel monkey ( Saimiri boliviensis boliviensis )
Studies on the reproductive mechanisms of the squirrel monkey have been hampered by inadequate measurements of luteinizing hormone (LH). The mouse interstitial cell bioassay, which measures testosterone production as the endpoint, was validated for use in the squirrel monkey by parallel responses of serum to LH standards and by in vivo responses to an LH‐releasing hormone (LHRH) analogue. The LH surge profile, as determined by daily blood samplin…
Detection and cultivation of intestinal trichomonads of squirrel monkeys ( Saimiri sciureus )
Routine examinations of fecal samples from squirrel monkeys suggested that intestinal trichomonads might be common inhabitants of these animals. In pursuit of these observations, microscopic examination of fecal suspensions and cultures have demonstrated a 100% incidence of trichomonads in 30 arbitrarily selected animals from a colony of more than 300 housed in groups of ten. The most prominent species was Pentatrichomonas hominis. A not yet full…
Seasonal changes of serum concentrations of estradiol and progesterone in Bolivian squirrel monkeys ( Saimiri sciureus )
Serial measurements of estradiol (E2) and progesterone (P) were used to describe the ovarian cycle of the Bolivian squirrel monkey. Group‐caged, sexually mature female squirrel monkeys, housed with males, were sampled daily between 0900 and 1100 hr. Sampling was carried out during the breeding and nonbreeding seasons, for periods of 19–20 days from September 1981 to May 1982. Seasonal differences in serum concentrations of E2 and P were found wit…
Diurnal variations of androgens in sexually mature male Bolivian squirrel monkeys ( Saimiri sciureus ) during the breeding season
To assess diurnal fluctuations of serum androgens and cortisol in adult male Bolivian squirrel monkeys, these steroids were measured at predetermined times (0300, 0900, and 2300 hours) during two separate 24‐hour periods in the breeding season (January 1983 and late November 1983). A significant diurnal change in serum cortisol was noted, with a nadir of 99.9 ± 11.9 μg/dl (x̄ ± SEM) at 2300 hours and a peak of 168.9 ± 7.8 μg/dl at 0900 hours. Con…
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Seasonal changes of serum concentrations of estradiol and progesterone in Bolivian squirrel monkeys ( Saimiri sciureus )
Serial measurements of estradiol (E2) and progesterone (P) were used to describe the ovarian cycle of the Bolivian squirrel monkey. Group‐caged, sexually mature female squirrel monkeys, housed with males, were sampled daily between 0900 and 1100 hr. Sampling was carried out during the breeding and nonbreeding seasons, for periods of 19–20 days from September 1981 to May 1982. Seasonal differences in serum concentrations of E2 and P were found wit…
Diurnal variations of androgens in sexually mature male Bolivian squirrel monkeys ( Saimiri sciureus ) during the breeding season
To assess diurnal fluctuations of serum androgens and cortisol in adult male Bolivian squirrel monkeys, these steroids were measured at predetermined times (0300, 0900, and 2300 hours) during two separate 24‐hour periods in the breeding season (January 1983 and late November 1983). A significant diurnal change in serum cortisol was noted, with a nadir of 99.9 ± 11.9 μg/dl (x̄ ± SEM) at 2300 hours and a peak of 168.9 ± 7.8 μg/dl at 0900 hours. Con…
Detection and cultivation of intestinal trichomonads of squirrel monkeys ( Saimiri sciureus )
Routine examinations of fecal samples from squirrel monkeys suggested that intestinal trichomonads might be common inhabitants of these animals. In pursuit of these observations, microscopic examination of fecal suspensions and cultures have demonstrated a 100% incidence of trichomonads in 30 arbitrarily selected animals from a colony of more than 300 housed in groups of ten. The most prominent species was Pentatrichomonas hominis. A not yet full…
Forthcoming article
Seasonal changes in serum dehydroepiandrosterone, androstenedione, and testosterone levels in the squirrel monkey ( Saimiri boliviensis boliviensis )
The squirrel monkey ( Saimiri boliviensis boliviensis ) has a well‐defined breeding season during which adult males undergo androgen‐dependent morphological changes, with acquisition of active spermatogenesis. To assess the hormonal events of this annual cycle, blood samples were obtained weekly from ten adult males, and serum was assayed for testosterone (T), androstenedione (ΔA), and dehydroepiandrosterone (DHEA). A significant seasonal variati…
Enteric trichomonads of squirrel monkeys ( Saimiri sp)
In a large breeding colony of squirrel monkeys, a previous study demonstrated apparent universal infestation of adult animals with enteric trichomonads. The potential of these organisms to act as a source of experimental variability and the potential pathogenic effects of parasitism in this species stimulated this study of organism acquisition and treatment. Age of natural infestation with trichomonads was determined from results of microscopic e…
In vitro bioactive luteinizing hormone assay shows cyclical, seasonal hormonal changes and response to luteinizing‐hormone releasing hormone in the squirrel monkey ( Saimiri boliviensis boliviensis )
Studies on the reproductive mechanisms of the squirrel monkey have been hampered by inadequate measurements of luteinizing hormone (LH). The mouse interstitial cell bioassay, which measures testosterone production as the endpoint, was validated for use in the squirrel monkey by parallel responses of serum to LH standards and by in vivo responses to an LH‐releasing hormone (LHRH) analogue. The LH surge profile, as determined by daily blood samplin…
Determination of lactogenic activity in the serum of the squirrel monkey ( Saimiri boliviensis ) using the Nb2 lymphoma bioassay
Determination of squirrel monkey prolactin by immunoassay has been hampered by the lack of antiserum specific to prolactin from this species. As an alternate method, we have investigated whether the Nb2 lymphoma bioassay could be adapted for routine measurement of the lactogenic activity of samples of squirrel monkey serum. The growth of the Nb2 cells is absolutely dependent on the presence of lactogens in the culture medium. The cells were maint…
Genetic relationships among three squirrel monkey types
Fourteen electrophoretically variable and 12 monomorphic erythrocytic and serum proteins were used to determine the genetic relationships among Bolivian squirrel monkeys ( Saimiri boliviensis boliviensis ), Peruvian squirrel monkeys ( Saimiri boliviensis peruviensis ), and Guyanese squirrel monkeys ( Saimiri sciureus sciureus ). The results supported the classification scheme of Hershkovitz ( AMERICAN JOURNAL OF PRIMATOLOGY 7:155–210, 1984), whic…
Confirmation of ovulation and characterization of luteinizing hormone and progesterone secretory patterns in cycling, isosexually housed Bolivian squirrel monkeys ( Saimiri boliviensis boliviensis )
In the female Bolivian squirrel monkey a much greater elevation of serum estradiol (E 2 ) was measured after mating than that observed in similary cycling monkeys that did not mate. This raised the possibility that cycling squirrel monkeys may not ovulate during nonmated cycles To test this hypothesis, we performed laparoscopies on nine isosexually housed, cycling monkeys to observe the ovaries after the luteinizing hormone (LH) surge, which was …
Characterization of prolactin and growth hormone immuno‐ and bioactivities in the pituitary gland and serum of the squirrel monkey (Saimiri boliviensis boliviensis)
The immunological and biological activities of growth hormone (GH) and prolactin (PRL) in the pituitary gland and serum of the squirrel monkey ( Saimiri boliviensis boliviensis ) have been studied. Proteins in pituitary homogenates were solubilized in 1% SDS, electrophoresed on 12% polyacrylamide gels, and transferred to nitrocellulose. Squirrel monkey GH and PRL were identified by immunoblotting with anti‐human GH antibodies and a monoclonal ant…
Age‐related hormonal differences in cycling squirrel monkeys ( Saimiri boliviensis boliviensis )
This study was planned to evaluate the poor reproductive performance of aged squirrel monkeys in a self‐sustaining breeding colony. Two groups of monkeys aged 6–8 years (Group 1), and >12 years (Group 2) were evaluated. During the midbreeding season, daily blood samples were obtained for a period of 35 days from 10 animals in each group. Blood samples were assayed for serum estradiol (E), progesterone (P), and bioassayable luteinizing hormone (bi…
Allomaternal interactions in the Bolivian squirrel monkey ( Saimiri boliviensis boliviensis )
Allomaternal behavior is defined as maternal‐like interactions between an infant and some animal other than its natural mother. The occurrence of allomothering can have a profound influence on the life of the infant and on the animal with which the infant interacts. Allomaternal interactions were studied during the first 6 months of life in 50 Bolivian squirrel monkeys in two different social settings. Allomaternal interactions began during the f…
Elevated ovarian expression and serum concentration of α inhibin in the luteal phase during follicular development in the squirrel monkey (Saimiri boliviensis) compared to the human
The goal of the present investigation was to determine in the squirrel monkey the source and pattern of inhibin, a hormone known to effect reproductive steroid levels via pituitary and ovarian mechanisms. Since this seasonally polyestrous species is known to have elevated serum levels of reproductive steroids compared to other primates, the levels of ovarian alpha subunit mRNA expression and serum total alpha inhibin, estradiol, progesterone, and…
Midcycle and luteal elevations of follicle stimulating hormone in squirrel monkeys (Saimiri boliviensis) during the estrous cycle
Follicle stimulating hormone (FSH) has fundamental importance in reproductive function, but its cyclic pattern has not previously been described in the squirrel monkey, due primarily to the lack of a suitable assay. An homologous radioimmunoassay (RIA) based on recombinant cynomolgus FSH measured changes in serum FSH relative to patterns of bioactive luteinizing hormone (LH), estradiol, and progesterone during the estrous cycle. FSH was observed …
Midcycle and luteal elevations of follicle stimulating hormone in squirrel monkeys (Saimiri boliviensis) during the estrous cycle
Follicle stimulating hormone (FSH) has fundamental importance in reproductive function, but its cyclic pattern has not previously been described in the squirrel monkey, due primarily to the lack of a suitable assay. An homologous radioimmunoassay (RIA) based on recombinant cynomolgus FSH measured changes in serum FSH relative to patterns of bioactive luteinizing hormone (LH), estradiol, and progesterone during the estrous cycle. FSH was observed …
Neonatal activity and state control differences among three squirrel monkey subspecies ( Saimiri sciureus sciureus, S. boliviensis boliviensis , and S. boliviensis peruviensis )
Squirrel monkeys are a long‐standing biomedical model, with multiple species and subspecies housed in research facilities. Few studies have examined the developmental differences between these subspecies, which may affect research outcomes. The primate neonatal neurobehavioral assessment was completed at 2 weeks of age with 279 dam‐reared squirrel monkeys (188 Saimiri boliviensis boliviensis , 45 S. b. peruviensis , and 46 Saimiri. sciureus sciur…
Biology (16 works) · Squirrel monkey (15 works) · Medicine (13 works) · Hormone (10 works) · Ecology (8 works) · Endocrinology (8 works) · Internal Medicine (8 works) · Zoology (7 works) · Estrous cycle (6 works) · Hypothalamic control of reproductive hormones (6 works)