Douglas M Bowden
Biographic Data
| ID | 8907128 |
|---|---|
| NAME | Douglas M Bowden |
| GIVEN NAMES | Douglas M |
| FAMILY NAME | Bowden |
| SIGNATURE | BOWDEN D M |
| AFFILIATIONS | University of Washington |
| ORCID | 0000-0001-5836-6070 |
| VERIFIED | Yes |
| TOTAL WORKS | 7 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 7 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1970 |
| LATEST PUBLICATION YEAR | 2000 |
| H-INDEX | 0 |
Behavior, appetite, and urinary cortisol responses by adult female pigtailed macaques to cage size, cage level, room change, and ketamine sedation
Pigtailed macaques (Macaca nemestrina) and longtailed macaques (M. fascicularis) show behavioral, ecological, and possible temperament differences, and their responses to the laboratory environment might therefore be quite different. We tested pigtailed macaques under the same conditions that were investigated in a previous study with longtailed macaques, using the same comprehensive set of physiological and behavioral measures of stress. First, …
Differences in stress reactivity of laboratory macaques measured by heart period and respiratory sinus arrhythmia
Some laboratory primates are more likely than others to react to anxiety-provoking stressors. Individuals that overreact to stressors may experience diminished psychological well-being and would be inappropriate for some experiments. The differences between reactive and nonreactive individuals may be reflected in heart period and respiratory sinus arrhythmia (RSA). Using surface electrodes and radio telemetry, we measured these two cardiac variab…
Sex differences in compatibility of pair‐housed adult longtailed macaques
This research was designed to evaluate the effects of same‐sex pair housing on the psychological well‐being of adult wild‐born longtailed macaques ( Macaca fascicularis ). We studied behavioral compatibility and stress as measured by urinary cortisol excretion in 15 pairs of each sex. Before they were housed together, the pairs were categorized by noncontact pairedpreference testing as preferred, nonpreferred, or randomly assigned partners. Every…
Urinary cortisol responses of longtailed macaques to five cage sizes, tethering, sedation, and room change
Urinary free cortisol responses to five cage sizes, cage level, room change, tethering adaptation, chronic catheterization, and ketamine sedation were measured in 14 female and 14 male wild‐born adult Macaca fascicularis. Urinary free cortisol, a physiological measure of psychological well‐being that can be collected unobtrusively, provided a measure of the animals' general adrenocortical response to various conditions over a time course of hours…
Relations among whole blood serotonin and sex, age, diet, and social status in Macaca nemestrina
Whole blood serotonin (WBS) determinations were made in 56 pigtailed macaques ( Macaca nemestrina ) with approximately equal numbers in three age groups: young‐adult (4–5 years), middle‐aged (13–14 years), and old (over 18 years). The animals were housed in ten living groups with one female and male of each age group in each living group. Half of the groups were fed a diet high in lipid, cholesterol, simple sugars, and sodium; the other half rece…
A periodic dosing model of fetal alcohol syndrome in the pig‐tailed macaque ( Macaca nemestrina )
A nonhuman primate on a periodic ethanol dosing schedule should provide a model of fetal alcohol syndrome (FAS) most relevant to the majority of pregnant women who are “social drinkers” and can exercise reasonable control over their ethanol intake. In this pilot study, four pregnant pig‐tailed macaques ( Macaca nemestrina ) received ethanol once a week from 40 days' gestation. Doses were 2.5 gm/kg for three moderate‐dose animals (MDAs) and 4.1 gm…
Current Soviet Psychological and Psychiatric Research with Nonhuman Primates
Primate research has a long history in the Soviet Union. As early as 1913, at The Darwin Museum in Moscow, Ladygina-Kots was studying the comparative behavioral development of young chimpanzees and of children. In 1927, one of the world's oldest and largest primate research centers was established at Sukhumi. Now known as the Institute of Experimental Pathology and Therapy, it makes available several thousand animals (including a dozen chimpanzee…
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Current Soviet Psychological and Psychiatric Research with Nonhuman Primates
Primate research has a long history in the Soviet Union. As early as 1913, at The Darwin Museum in Moscow, Ladygina-Kots was studying the comparative behavioral development of young chimpanzees and of children. In 1927, one of the world's oldest and largest primate research centers was established at Sukhumi. Now known as the Institute of Experimental Pathology and Therapy, it makes available several thousand animals (including a dozen chimpanzee…
A periodic dosing model of fetal alcohol syndrome in the pig‐tailed macaque ( Macaca nemestrina )
A nonhuman primate on a periodic ethanol dosing schedule should provide a model of fetal alcohol syndrome (FAS) most relevant to the majority of pregnant women who are “social drinkers” and can exercise reasonable control over their ethanol intake. In this pilot study, four pregnant pig‐tailed macaques ( Macaca nemestrina ) received ethanol once a week from 40 days' gestation. Doses were 2.5 gm/kg for three moderate‐dose animals (MDAs) and 4.1 gm…
Relations among whole blood serotonin and sex, age, diet, and social status in Macaca nemestrina
Whole blood serotonin (WBS) determinations were made in 56 pigtailed macaques ( Macaca nemestrina ) with approximately equal numbers in three age groups: young‐adult (4–5 years), middle‐aged (13–14 years), and old (over 18 years). The animals were housed in ten living groups with one female and male of each age group in each living group. Half of the groups were fed a diet high in lipid, cholesterol, simple sugars, and sodium; the other half rece…
Urinary cortisol responses of longtailed macaques to five cage sizes, tethering, sedation, and room change
Urinary free cortisol responses to five cage sizes, cage level, room change, tethering adaptation, chronic catheterization, and ketamine sedation were measured in 14 female and 14 male wild‐born adult Macaca fascicularis. Urinary free cortisol, a physiological measure of psychological well‐being that can be collected unobtrusively, provided a measure of the animals' general adrenocortical response to various conditions over a time course of hours…
Sex differences in compatibility of pair‐housed adult longtailed macaques
This research was designed to evaluate the effects of same‐sex pair housing on the psychological well‐being of adult wild‐born longtailed macaques ( Macaca fascicularis ). We studied behavioral compatibility and stress as measured by urinary cortisol excretion in 15 pairs of each sex. Before they were housed together, the pairs were categorized by noncontact pairedpreference testing as preferred, nonpreferred, or randomly assigned partners. Every…
Differences in stress reactivity of laboratory macaques measured by heart period and respiratory sinus arrhythmia
Some laboratory primates are more likely than others to react to anxiety-provoking stressors. Individuals that overreact to stressors may experience diminished psychological well-being and would be inappropriate for some experiments. The differences between reactive and nonreactive individuals may be reflected in heart period and respiratory sinus arrhythmia (RSA). Using surface electrodes and radio telemetry, we measured these two cardiac variab…
Behavior, appetite, and urinary cortisol responses by adult female pigtailed macaques to cage size, cage level, room change, and ketamine sedation
Pigtailed macaques (Macaca nemestrina) and longtailed macaques (M. fascicularis) show behavioral, ecological, and possible temperament differences, and their responses to the laboratory environment might therefore be quite different. We tested pigtailed macaques under the same conditions that were investigated in a previous study with longtailed macaques, using the same comprehensive set of physiological and behavioral measures of stress. First, …
Biology (6 works) · Medicine (5 works) · Primate Behavior and Ecology (4 works) · Anesthesia (3 works) · Endocrinology (3 works) · Internal Medicine (3 works) · Psychology (3 works) · Stress Responses and Cortisol (3 works) · Animal Behavior and Reproduction (2 works) · Animal Nutrition and Physiology (2 works)