Nicholas Feasey
Biographic Data
| ID | 9002466 |
|---|---|
| NAME | Nicholas Feasey |
| GIVEN NAMES | Nicholas |
| FAMILY NAME | Feasey |
| SIGNATURE | FEASEY N |
| AFFILIATIONS | University of Liverpool |
| ORCID | 0000-0003-4041-1405 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 10 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2020 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Co-creating community-driven solutions and policy priorities to address antimicrobial resistance through Responsive Dialogues
Inappropriate antibiotics use due to low public knowledge and awareness contributes to the growing Antimicrobial Resistance (AMR) burden, especially in low- and middle-income countries (LMICs). The aim of Responsive Dialogues (RDs) is to engage communities and key stakeholders to share information, galvanize action and create local solutions to reduce the burden of AMR. RDs promote collaborative problem-solving and have been identified as a poten…
Factors associated with positive blood cultures in children in nine African and Asian countries
BACKGROUND: Blood culture (BC) in children has relatively low diagnostic yield and high contamination rates, limiting cost-effectiveness. We aimed to determine readily available baseline characteristics to identify hospitalised children with a likelihood of higher diagnostic yield in low- and middle-income countries. METHODS: We used data from ACORN2, a prospective clinical surveillance network including 19 hospitals across Africa and Asia. We in…
Cost-effectiveness of wastewater-based environmental surveillance for Sars-CoV-2 in Blantyre, Malawi and Kathmandu, Nepal
Wastewater-based environmental surveillance (ES) has been demonstrated to provide an early warning signal to predict variant-driven waves of pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our study evaluated the potential cost-effectiveness of ES for SARS-CoV-2 compared with clinical testing alone. We used the Covasim agent-based model of COVID-19 to simulate disease transmission for hypothetical populations in Bl…
“Arming half-baked people with weapons!” Information enclaving among professionals and the need for a care-centred model for antibiotic use information in Uganda, Tanzania and Malawi
BACKGROUND: The overuse of antimicrobial medicines is a global health concern, including as a major driver of antimicrobial resistance. In many low- and middle-income countries, a substantial proportion of antibiotics are purchased over-the-counter without a prescription. But while antibiotics are widely available, information on when and how to use them is not. OBJECTIVE: We aimed to understand the acceptability among experts and professionals o…
Household antibiotic use in Malawi
Antimicrobial resistance (AMR) is a significant threat to public health. Use of antibiotics, particularly in contexts where weaker regulatory frameworks make informal access easier, has been identified as an important driver of AMR. However, knowledge is limited about the ways antibiotics are used in communities in Malawi and sub-Saharan Africa. Between April and July 2021, we undertook a cross-sectional survey of community antibiotic use practic…
Different clinical features in Malawian outpatients presenting with Covid-19 prior to and during Omicron variant dominance
The SARS-CoV-2 Omicron variant has resulted in a high number of cases, but a relatively low incidence of severe disease and deaths, compared to the pre-Omicron variants. Therefore, we assessed the differences in symptom prevalence between Omicron and pre-Omicron infections in a sub-Saharan African population. We collected data from outpatients presenting at two primary healthcare facilities in Blantyre, Malawi, from November 2020 to March 2022. E…
Individual and population level costs and health-related quality of life outcomes of third-generation cephalosporin resistant bloodstream infection in Blantyre, Malawi
Data which accurately enumerate the economic costs of antimicrobial resistance (AMR) in low- and middle- income countries are essential. This study aimed to quantify the impact of third-generation cephalosporin resistant (3GC-R) bloodstream infection (BSI) on economic and health related quality of life outcomes for adult patients in Blantyre, Malawi. Participants were recruited from a prospective, longitudinal cohort study of hospitalised patient…
Global burden of bacterial antimicrobial resistance in 2019
BACKGROUND: Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen-drug combinations in select locations. To our knowledge, this study presents the most comprehensive estimates of AMR burden to date. METHODS: We estimated deaths and disability-adjusted life-years (DALYs) a…
Cost of wastewater-based environmental surveillance for Sars-CoV-2
Environmental surveillance of rivers and wastewater for SARS-CoV-2 detection has been explored as an innovative way to surveil the pandemic. This study estimated the economic costs of conducting wastewater-based environmental surveillance for SARS-CoV-2 to inform decision making if countries consider continuing these efforts. We estimated the cost of two SARS-CoV-2 environmental surveillance pilot studies conducted in Blantyre, Malawi, and Kathma…
Leapfrogging laboratories
The scope and trajectory of today’s escalating antimicrobial resistance (AMR) crisis is inadequately captured by existing surveillance systems, particularly those of lower income settings. AMR surveillance systems typically collate data from routine culture and susceptibility testing performed in diagnostic bacteriology laboratories to support healthcare. Limited access to high quality culture and susceptibility testing results in the dearth of A…
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Leapfrogging laboratories
The scope and trajectory of today’s escalating antimicrobial resistance (AMR) crisis is inadequately captured by existing surveillance systems, particularly those of lower income settings. AMR surveillance systems typically collate data from routine culture and susceptibility testing performed in diagnostic bacteriology laboratories to support healthcare. Limited access to high quality culture and susceptibility testing results in the dearth of A…
Global burden of bacterial antimicrobial resistance in 2019
BACKGROUND: Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen-drug combinations in select locations. To our knowledge, this study presents the most comprehensive estimates of AMR burden to date. METHODS: We estimated deaths and disability-adjusted life-years (DALYs) a…
Cost of wastewater-based environmental surveillance for Sars-CoV-2
Environmental surveillance of rivers and wastewater for SARS-CoV-2 detection has been explored as an innovative way to surveil the pandemic. This study estimated the economic costs of conducting wastewater-based environmental surveillance for SARS-CoV-2 to inform decision making if countries consider continuing these efforts. We estimated the cost of two SARS-CoV-2 environmental surveillance pilot studies conducted in Blantyre, Malawi, and Kathma…
Household antibiotic use in Malawi
Antimicrobial resistance (AMR) is a significant threat to public health. Use of antibiotics, particularly in contexts where weaker regulatory frameworks make informal access easier, has been identified as an important driver of AMR. However, knowledge is limited about the ways antibiotics are used in communities in Malawi and sub-Saharan Africa. Between April and July 2021, we undertook a cross-sectional survey of community antibiotic use practic…
Different clinical features in Malawian outpatients presenting with Covid-19 prior to and during Omicron variant dominance
The SARS-CoV-2 Omicron variant has resulted in a high number of cases, but a relatively low incidence of severe disease and deaths, compared to the pre-Omicron variants. Therefore, we assessed the differences in symptom prevalence between Omicron and pre-Omicron infections in a sub-Saharan African population. We collected data from outpatients presenting at two primary healthcare facilities in Blantyre, Malawi, from November 2020 to March 2022. E…
Individual and population level costs and health-related quality of life outcomes of third-generation cephalosporin resistant bloodstream infection in Blantyre, Malawi
Data which accurately enumerate the economic costs of antimicrobial resistance (AMR) in low- and middle- income countries are essential. This study aimed to quantify the impact of third-generation cephalosporin resistant (3GC-R) bloodstream infection (BSI) on economic and health related quality of life outcomes for adult patients in Blantyre, Malawi. Participants were recruited from a prospective, longitudinal cohort study of hospitalised patient…
“Arming half-baked people with weapons!” Information enclaving among professionals and the need for a care-centred model for antibiotic use information in Uganda, Tanzania and Malawi
BACKGROUND: The overuse of antimicrobial medicines is a global health concern, including as a major driver of antimicrobial resistance. In many low- and middle-income countries, a substantial proportion of antibiotics are purchased over-the-counter without a prescription. But while antibiotics are widely available, information on when and how to use them is not. OBJECTIVE: We aimed to understand the acceptability among experts and professionals o…
Factors associated with positive blood cultures in children in nine African and Asian countries
BACKGROUND: Blood culture (BC) in children has relatively low diagnostic yield and high contamination rates, limiting cost-effectiveness. We aimed to determine readily available baseline characteristics to identify hospitalised children with a likelihood of higher diagnostic yield in low- and middle-income countries. METHODS: We used data from ACORN2, a prospective clinical surveillance network including 19 hospitals across Africa and Asia. We in…
Cost-effectiveness of wastewater-based environmental surveillance for Sars-CoV-2 in Blantyre, Malawi and Kathmandu, Nepal
Wastewater-based environmental surveillance (ES) has been demonstrated to provide an early warning signal to predict variant-driven waves of pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our study evaluated the potential cost-effectiveness of ES for SARS-CoV-2 compared with clinical testing alone. We used the Covasim agent-based model of COVID-19 to simulate disease transmission for hypothetical populations in Bl…
Co-creating community-driven solutions and policy priorities to address antimicrobial resistance through Responsive Dialogues
Inappropriate antibiotics use due to low public knowledge and awareness contributes to the growing Antimicrobial Resistance (AMR) burden, especially in low- and middle-income countries (LMICs). The aim of Responsive Dialogues (RDs) is to engage communities and key stakeholders to share information, galvanize action and create local solutions to reduce the burden of AMR. RDs promote collaborative problem-solving and have been identified as a poten…
Medicine (7 works) · Antibiotic Use and Resistance (6 works) · Health care (5 works) · Antibiotic Resistance in Bacteria (4 works) · Business (4 works) · Disease (4 works) · Economic growth (4 works) · Nursing (4 works) · Antibiotic resistance (3 works) · Biology (3 works)