Chu Zheng
Biographic Data
| ID | 9020029 |
|---|---|
| NAME | Chu Zheng |
| GIVEN NAMES | Chu |
| FAMILY NAME | Zheng |
| SIGNATURE | ZHENG C |
| AFFILIATIONS | Xuzhou Medical College |
| ORCID | 0000-0003-3309-208X |
| VERIFIED | Yes |
| TOTAL WORKS | 7 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 7 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2023 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk
Background: Previous studies established handgrip strength (HGS) as a potential risk factor for cardiovascular diseases (CVD). However, existing studies focused exclusively on baseline HGS and neglected longitudinal changes in HGS during follow-up. Thus, our aim was to investigate the associations of transitions and dynamic burdens of HGS with incident CVD risk. Methods: We analyzed data from the UK Biobank (UKB), the China Health and Retirement …
Unravelling the role of inflammatory markers in coronary artery disease risk via association, mediation and prediction analyses
Background: Systemic inflammation plays a critical role in coronary artery disease (CAD), yet comprehensive profiling of inflammatory markers and their integration into predictive models remain incompletely characterised. We here sought to identify key CAD-related inflammation markers and construct an integrated inflammatory risk score (IRS) to enhance conventional cardiovascular risk prediction. Methods: Associations between 18 complete blood co…
Sarcopenia prediction model based on machine learning and SHAP values for community-based older adults with cardiovascular disease in China
Background: Sarcopenia (SP), is recognized as a complication of cardiovascular disease (CVD), but few relevant diagnostic models have been developed. This study aims to establish an interpretable diagnostic model for the occurrence of SP in older adult CVD patients living in Chinese community-dwelling (CD). Methods: We randomly selected participants with CVD recruited from CHARLS from 2011 to 2015 and divided them into a training set and a test s…
Influence and role of polygenic risk score in the development of 32 complex diseases
Background: The polygenic risk score (PRS) has been perceived as advantageous in predicting the risk of complex diseases compared to other measures. We aimed to systematically evaluate the influence of PRS on disease outcome and to explore its predictive value. Methods: We comprehensively assessed the relationship between PRS and 32 complex diseases in the UK Biobank. We used Cox models to estimate the effects of PRS on the incidence risk. Then, …
Longitudinal patterns of cognitive function and depression
Background: With the acceleration of population aging, cognitive impairment and depression have become serious public health challenges in countries around the world. The influencing factors of cognitive trajectory, depression trajectory, and dual trajectories in middle-aged and elderly adults have not been fully studied. Methods: This study used data from the China Health and Retirement Longitudinal Study database spanning from 2011-2018. Group-…
Uncovering psychologically mediated pathways to cardiovascular diseases
The research results remind us to pay attention to the impact of psychological factors on the CM population, so as to reduce the incidence rate of different types of CVDs
Variety ACEs and risk of developing anxiety, depression, or anxiety-depression co-morbidity
The prevalence of anxiety-depression comorbidity was highest across ACE scores after controlling for confounding factors and had a significant effect on each category of ACEs
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Variety ACEs and risk of developing anxiety, depression, or anxiety-depression co-morbidity
The prevalence of anxiety-depression comorbidity was highest across ACE scores after controlling for confounding factors and had a significant effect on each category of ACEs
Sarcopenia prediction model based on machine learning and SHAP values for community-based older adults with cardiovascular disease in China
Background: Sarcopenia (SP), is recognized as a complication of cardiovascular disease (CVD), but few relevant diagnostic models have been developed. This study aims to establish an interpretable diagnostic model for the occurrence of SP in older adult CVD patients living in Chinese community-dwelling (CD). Methods: We randomly selected participants with CVD recruited from CHARLS from 2011 to 2015 and divided them into a training set and a test s…
Influence and role of polygenic risk score in the development of 32 complex diseases
Background: The polygenic risk score (PRS) has been perceived as advantageous in predicting the risk of complex diseases compared to other measures. We aimed to systematically evaluate the influence of PRS on disease outcome and to explore its predictive value. Methods: We comprehensively assessed the relationship between PRS and 32 complex diseases in the UK Biobank. We used Cox models to estimate the effects of PRS on the incidence risk. Then, …
Longitudinal patterns of cognitive function and depression
Background: With the acceleration of population aging, cognitive impairment and depression have become serious public health challenges in countries around the world. The influencing factors of cognitive trajectory, depression trajectory, and dual trajectories in middle-aged and elderly adults have not been fully studied. Methods: This study used data from the China Health and Retirement Longitudinal Study database spanning from 2011-2018. Group-…
Uncovering psychologically mediated pathways to cardiovascular diseases
The research results remind us to pay attention to the impact of psychological factors on the CM population, so as to reduce the incidence rate of different types of CVDs
Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk
Background: Previous studies established handgrip strength (HGS) as a potential risk factor for cardiovascular diseases (CVD). However, existing studies focused exclusively on baseline HGS and neglected longitudinal changes in HGS during follow-up. Thus, our aim was to investigate the associations of transitions and dynamic burdens of HGS with incident CVD risk. Methods: We analyzed data from the UK Biobank (UKB), the China Health and Retirement …
Unravelling the role of inflammatory markers in coronary artery disease risk via association, mediation and prediction analyses
Background: Systemic inflammation plays a critical role in coronary artery disease (CAD), yet comprehensive profiling of inflammatory markers and their integration into predictive models remain incompletely characterised. We here sought to identify key CAD-related inflammation markers and construct an integrated inflammatory risk score (IRS) to enhance conventional cardiovascular risk prediction. Methods: Associations between 18 complete blood co…
Disease (4 works) · Medicine (4 works) · Adipokines, Inflammation, and Metabolic Diseases (2 works) · Biology (2 works) · Child Abuse and Trauma (2 works) · China (2 works) · Depression (economics (2 works) · Gerontology (2 works) · Internal Medicine (2 works) · Nutrition and Health in Aging (2 works)