Birgitta Gleeson
Biographic Data
| ID | 9067409 |
|---|---|
| NAME | Birgitta Gleeson |
| GIVEN NAMES | Birgitta |
| FAMILY NAME | Gleeson |
| SIGNATURE | GLEESON B |
| AFFILIATIONS | FIND |
| ORCID | 0009-0003-0791-7735 |
| VERIFIED | Yes |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 5 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2022 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Aligning neonatal sepsis triage diagnostics with WHO target product profiles in low- and middle-income countries
Neonatal sepsis is a leading cause of infant morbidity and mortality in low- and middle-income countries (LMICs), yet despite this, progress in the development and implementation of effective diagnostics has been limited. Current diagnostic methods rely on clinical assessments of nonspecific signs and symptoms, limited laboratory testing and technologies that are inaccessible, unaffordable or unsuitable for resource-constrained settings. There is…
Rapid bacterial identification and resistance detection using a low complexity molecular diagnostic platform in Zimbabwe
BACKGROUND: Sepsis is a major cause of mortality in low-resource settings. Effective microbiological culture services are a bottleneck in diagnosis and surveillance. AIM: We aimed to evaluate the performance of the BIOFIRE FILMARRAY Blood Culture Identification 2 (BCID2, bioMérieux) assay in a low-resource setting laboratory in comparison to standard practice. METHODS: This five month prospective validation study included all positive blood cultu…
Evaluation of a novel point-of-care lateral flow assay screening for Neisseria gonorrhoeae infection among pregnant women in Zimbabwe
Affordable, easy-to-use and rapid diagnostics may support a move away from syndromic management for sexually transmitted infections (STIs) in resource-constrained settings. A lateral flow assay for Neisseria gonorrhoeae (NG-LFA) has shown high sensitivity and specificity (>90%) in symptomatic individuals. We investigated the performance and acceptability of this assay as a screening tool for NG among pregnant women. This evaluation was embedded w…
A call to bridge the diagnostic gap
BOX Low- and middle-income countries (LMICs) bear the greatest burden of neonatal mortality, with sepsis being a major contributor
Diagnostic tests to mitigate the antimicrobial resistance pandemic—Still the problem child
The UK Government's 2015 Antimicrobial Resistance (AMR) Review Seven years on, this remains purely aspirational, and diagnostics continue to be the problem child of the AMR pandemic. COVID-19 has demonstrated just how far we still are from such a goal; despite rapid diagnostics for COVID-19 being developed within months of identification of SARS-CoV-2, the virus was able to drive global, large-scale inappropriate antibiotic prescribing for unsubs…
No prominent works on this page.
Diagnostic tests to mitigate the antimicrobial resistance pandemic—Still the problem child
The UK Government's 2015 Antimicrobial Resistance (AMR) Review Seven years on, this remains purely aspirational, and diagnostics continue to be the problem child of the AMR pandemic. COVID-19 has demonstrated just how far we still are from such a goal; despite rapid diagnostics for COVID-19 being developed within months of identification of SARS-CoV-2, the virus was able to drive global, large-scale inappropriate antibiotic prescribing for unsubs…
A call to bridge the diagnostic gap
BOX Low- and middle-income countries (LMICs) bear the greatest burden of neonatal mortality, with sepsis being a major contributor
Rapid bacterial identification and resistance detection using a low complexity molecular diagnostic platform in Zimbabwe
BACKGROUND: Sepsis is a major cause of mortality in low-resource settings. Effective microbiological culture services are a bottleneck in diagnosis and surveillance. AIM: We aimed to evaluate the performance of the BIOFIRE FILMARRAY Blood Culture Identification 2 (BCID2, bioMérieux) assay in a low-resource setting laboratory in comparison to standard practice. METHODS: This five month prospective validation study included all positive blood cultu…
Evaluation of a novel point-of-care lateral flow assay screening for Neisseria gonorrhoeae infection among pregnant women in Zimbabwe
Affordable, easy-to-use and rapid diagnostics may support a move away from syndromic management for sexually transmitted infections (STIs) in resource-constrained settings. A lateral flow assay for Neisseria gonorrhoeae (NG-LFA) has shown high sensitivity and specificity (>90%) in symptomatic individuals. We investigated the performance and acceptability of this assay as a screening tool for NG among pregnant women. This evaluation was embedded w…
Aligning neonatal sepsis triage diagnostics with WHO target product profiles in low- and middle-income countries
Neonatal sepsis is a leading cause of infant morbidity and mortality in low- and middle-income countries (LMICs), yet despite this, progress in the development and implementation of effective diagnostics has been limited. Current diagnostic methods rely on clinical assessments of nonspecific signs and symptoms, limited laboratory testing and technologies that are inaccessible, unaffordable or unsuitable for resource-constrained settings. There is…
Medicine (4 works) · Bacterial Identification and Susceptibility Testing (3 works) · Microbiology (3 works) · Neonatal and Maternal Infections (3 works) · Sepsis (3 works) · Antibiotics (2 works) · Biology (2 works) · Diagnostic test (2 works) · Internal Medicine (2 works) · Neonatal sepsis (2 works)