Heshan Kuruppu
Biographic Data
| ID | 9070588 |
|---|---|
| NAME | Heshan Kuruppu |
| GIVEN NAMES | Heshan |
| FAMILY NAME | Kuruppu |
| SIGNATURE | KURUPPU H |
| AFFILIATIONS | University of Sri Jayewardenepura |
| ORCID | 0009-0005-8745-8202 |
| VERIFIED | Yes |
| TOTAL WORKS | 4 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 4 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 0 |
Molecular Epidemiology of AY.28 and AY.104 Delta Sub-lineages in Sri Lanka
Background The worst SARS-CoV-2 outbreak in Sri Lanka was due to the two Sri Lankan delta sub-lineages AY.28 and AY.104. We proceeded to further characterize the mutations and clinical disease severity of these two sub-lineages. Methods 705 delta SARS-CoV-2 genomes sequenced by our laboratory from mid-May to November 2021 using Illumina and Oxford Nanopore were included in the analysis. The clinical disease severity of 440/705 individuals were fu…
Epidemiological and virological factors determining dengue transmission in Sri Lanka during the Covid-19 pandemic
With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 202…
Antibody responses to Sinopharm/BBIBP-CorV in pregnant mothers in Sri Lanka
Background There are limited data regarding the safety and immunogenicity of the Sinopharm/BBIBP-CorV vaccine in pregnancy. Therefore, we sought to investigate the antibody responses and maternal and fetal adverse events following this vaccine in pregnant mothers in Sri Lanka. Methods and findings SARS-CoV-2 receptor binding domain (RBD) specific total antibodies and ACE2 blocking antibodies were measured by ELISA in pregnant mothers (n = 94) who…
Seroprevalence of Sars-CoV-2 Infection in the Colombo Municipality Region, Sri Lanka
Background: As the Municipality Council area in Colombo (CMC) experienced the highest number of cases until the end of January 2021, in Sri Lanka, we carried out a serosurvey prior to initiation of the vaccination program to understand the extent of the SARS-CoV-2 outbreak. Methods: SARS-CoV-2 seropositivity was determined in 2,547 individuals between the ages of 10–86 years, by the Wantai total antibody ELISA. We also compared seroprevalence usi…
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Seroprevalence of Sars-CoV-2 Infection in the Colombo Municipality Region, Sri Lanka
Background: As the Municipality Council area in Colombo (CMC) experienced the highest number of cases until the end of January 2021, in Sri Lanka, we carried out a serosurvey prior to initiation of the vaccination program to understand the extent of the SARS-CoV-2 outbreak. Methods: SARS-CoV-2 seropositivity was determined in 2,547 individuals between the ages of 10–86 years, by the Wantai total antibody ELISA. We also compared seroprevalence usi…
Molecular Epidemiology of AY.28 and AY.104 Delta Sub-lineages in Sri Lanka
Background The worst SARS-CoV-2 outbreak in Sri Lanka was due to the two Sri Lankan delta sub-lineages AY.28 and AY.104. We proceeded to further characterize the mutations and clinical disease severity of these two sub-lineages. Methods 705 delta SARS-CoV-2 genomes sequenced by our laboratory from mid-May to November 2021 using Illumina and Oxford Nanopore were included in the analysis. The clinical disease severity of 440/705 individuals were fu…
Epidemiological and virological factors determining dengue transmission in Sri Lanka during the Covid-19 pandemic
With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the end of 2021. We sought to study the contribution of virological factors, human mobility, school closure and mosquito factors in affecting these changes in dengue transmission in Sri Lanka during this time. To understand the reasons for the differences in the dengue case numbers in 2020 to 202…
Antibody responses to Sinopharm/BBIBP-CorV in pregnant mothers in Sri Lanka
Background There are limited data regarding the safety and immunogenicity of the Sinopharm/BBIBP-CorV vaccine in pregnancy. Therefore, we sought to investigate the antibody responses and maternal and fetal adverse events following this vaccine in pregnant mothers in Sri Lanka. Methods and findings SARS-CoV-2 receptor binding domain (RBD) specific total antibodies and ACE2 blocking antibodies were measured by ELISA in pregnant mothers (n = 94) who…
Medicine (4 works) · Sri lanka (4 works) · Biology (3 works) · Internal Medicine (3 works) · SARS-CoV-2 and COVID-19 Research (3 works) · Virology (3 works) · Antibody (2 works) · COVID-19 Clinical Research Studies (2 works) · COVID-19 epidemiological studies (2 works) · Demography (2 works)