Mainga Hamaluba

Biographic Data

ID9075380
NAMEMainga Hamaluba
GIVEN NAMESMainga
FAMILY NAMEHamaluba
SIGNATUREHAMALUBA M
AFFILIATIONSKenya Medical Research Institute
ORCID0000-0002-0266-1414
VERIFIEDYes
TOTAL WORKS4
TOTAL CITATIONS0
AUTHOR COUNT4
EDITOR COUNT0
FIRST PUBLICATION YEAR2020
LATEST PUBLICATION YEAR2026
H-INDEX0

  • A cost-consequence analysis of the children’s administration oxygenation strategies trial (Coast) in severe pneumonia

    Open AccessOrlagh U Carroll, Richard Grieve et al.ARTICLEPLOS Global Public Health2026

    Oxygen supplementation is a recommended treatment for children with severe pneumonia or hypoxaemia. The open, fractional-factorial Children’s Oxygen Administration Strategies Trial (COAST) recruited Kenyan and Ugandan children with severe pneumonia and hypoxaemia. Participants in the severe hypoxaemia stratum (SpO 2 2 80–91%) to HFNT, LFO or permissive hypoxaemia (ratio 1:1:2). The trial stopped early and there is ongoing uncertainty about the cl…

  • Undertaking Community Engagement for a Controlled Human Malaria Infection Study in Kenya

    Open AccessNoni Mumba, Patricia Njuguna et al.ARTICLEFrontiers in Public Health2022

    Human infection studies (HIS) involve deliberately infecting healthy volunteers with disease-causing pathogens under controlled conditions. These studies are “controlled” by way of using specific types of pathogens, including dose, and the availability of emergency medical facilities to research volunteers. Most HIS involve diseases whose treatment is known and are done to accelerate the development of novel therapeutics such as vaccines, to addr…

  • Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against Sars-CoV-2

    Open AccessMerryn Voysey, Sue Ann Costa Clemens et al.ARTICLEThe Lancet2021

    Background A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. Methods This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Afri…

  • Deliberately infecting healthy volunteers with malaria parasites

    Open AccessIrene Jao, Vicki Marsh et al.ARTICLEBioethics2020

    Controlled human malaria infection (CHMI) studies involve the deliberate infection of healthy volunteers with malaria parasites under controlled conditions to study immune responses and/or test drug or vaccine efficacy. An empirical ethics study was embedded in a CHMI study at a Kenyan research programme to explore stakeholders’ perceptions and experiences of deliberate infection and moral implications of these. Data for this qualitative study we…