Deborah A Bolnick
Datos Biográficos
| ID | 90904 |
|---|---|
| NOMBRE | Deborah A Bolnick |
| NOMBRES | Deborah A |
| APELLIDO | Bolnick |
| FIRMA | BOLNICK D A |
| AFILIACIONES | The University of Texas at Austin |
| ORCID | 0000-0001-8444-5127 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 28 |
| TOTAL DE CITAS | 251 |
| TOTAL COMO AUTOR | 28 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2003 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2022 |
| ÍNDICE H | 10 |
Parallel evolution in human populations
Parallel evolution—where different populations evolve similar traits in response to similar environments—has been a topic of growing interest to biologists and biological anthropologists for decades. Parallel evolution occurs in human populations thanks to myriad biological and cultural mechanisms that permit humans to survive and thrive in diverse environments worldwide. Because humans shape and are shaped by their environments, biocultural appr…
An ethical crisis in ancient DNA research
In recent years, the field of paleogenomics has grown into an exciting and rapidly advancing area of scientific inquiry. However, scientific work in this field has far outpaced the discipline's dialogue about research ethics. In particular, Indigenous peoples have argued that the paleogenomics revolution has produced a 'vampire science' that perpetuates biocolonialist traditions of extracting Indigenous bodies and heritage without the consent of,…
Constrained Agency while Negotiating Spanish Colonialism
Spanish colonial rule in Peru was marked by dramatic changes to indigenous mortuary customs, bodily practices, and morbidity profiles. However, that era of transformation was not solely shaped by Spanish policies; Native Andeans creatively negotiated with those newcomers, sculpting novel practices that sometimes integrated, and other times challenged, the Spanish agenda. Theoretical perspectives on the constrained agency of indigenous communities…
AAPA Statement on Race and Racism
Race does not provide an accurate representation of human biological variation. It was never accurate in the past, and it remains inaccurate when referencing contemporary human populations. Humans are not divided biologically into distinct continental types or racial genetic clusters. Instead, the Western concept of race must be understood as a classification system that emerged from, and in support of, European colonialism, oppression, and discr…
Interpreting and communicating genetic variation in 2019
Situating Science
How Academic Diversity Is Transforming Scientific Knowledge in Biological Anthropology
A framework for enhancing ethical genomic research with Indigenous communities
Integration of genomic technology into healthcare settings establishes new capabilities to predict disease susceptibility and optimize treatment regimes. Yet, Indigenous peoples remain starkly underrepresented in genetic and clinical health research and are unlikely to benefit from such efforts. To foster collaboration with Indigenous communities, we propose six principles for ethical engagement in genomic research: understand existing regulation…
The Archaeology of Commoner Social Memories and Legitimizing Histories
Chaco Canyon Dig Unearths Ethical Concerns
The fijield of paleogenomics (the study of ancient genomes) is rapidly advancing, with more robust methods of isolating ancient DNA and increasing access to next-generation DNA sequencing technology. As these studies progress, many important ethical issues have emerged that should be considered when ancient Native American remains, whom we refer to as ancestors, are used in research. We highlight a 2017 article by Kennett et al., “Archaeogenomic …
Native American Genomics and Population Histories
Studies of Native American genetic diversity and population history have been transformed over the last decade by important developments in anthropological genetics. During this time, researchers have adopted new DNA technologies and computational approaches for analyzing genomic data, and they have become increasingly sensitive to the views of research participants and communities. As new methods are applied to long-standing questions, and as mo…
Abstracts ‐ AAPA Presentations
Spanish colonialism had profound genetic effects on native populations in central Mexico. Previous studies have shown that gene flow from Spanish colonists and African slaves introduced new genetic variants into indigenous populations, but the magnitude of this genetic impact likely varied across communities. While Spanish colonists interacted extensively with some indigenous communities, other communities had much less direct contact. Spanish co…
Does Mitochondrial Haplogroup X Indicate Ancient Trans-Atlantic Migration to the Americas? A Critical Re-Evaluation
It might seem strange for an article to focus largely on the history of a single mitochondrial haplogroup in an era when complete genome sequencing is becoming more common. But as recent publicatio
Combating Racial Health Disparities through Medical Education
Despite major public health initiatives, significant disparities persist among racially and ethnically defined groups in the prevalence of disease, access to medical care, quality of medical care, and health outcomes for common causes of morbidity and mortality in the United States. It is critical that we develop new and creative strategies to address such inequities; mitigate the social, environmental, institutional, and genetic determinants of …
Ancient DNA from the S child site in I llinois
Archaeologists have long debated whether rapid cultural change in the archaeological record is due to in situ developments, migration of a new group into the region, or the spread of new cultural practices into an area through existing social networks, with the local peoples adopting and adapting practices from elsewhere as they see fit (acculturation). Researchers have suggested each of these explanations for the major cultural transition that o…
Late Pleistocene Human Skeleton and mtDNA Link Paleoamericans and Modern Native Americans
American Beauty Modern Native American ancestry traces back to an East Asian migration across Beringia. However, some Native American skeletons from the late Pleistocene show phenotypic characteristics more similar to other, more geographically distant, human populations. Chatters et al. (p. 750 ) describe a skeleton with a Paleoamerican phenotype from the eastern Yucatan, dating to approximately 12 to 13 thousand years ago, with a relatively com…
Opsin Genes and Visual Ecology in a Nocturnal Folivorous Lemur
Clines Without Classes
This article examines Shiao, Bode, Beyer, and Selvig's (2012) arguments in their article 'The Genomic Challenge to the Social Construction of Race' and finds that their claims are based on fundamentally flawed interpretations of current genetic research. We discuss current genomic and genetic knowledge about human biological variation to demonstrate why and how Shiao et al.'s recommendations for future sociological studies and social policy, base…
Brief communication
In this study, we explore the geographic and temporal distribution of a unique variant of the O blood group allele called O1v G542A , which has been shown to be shared among Native Americans but is rare in other populations. O1v G542A was previously reported in Native American populations in Mesoamerica and South America, and has been proposed as an ancestry informative marker. We investigated whether this allele is also found in the Tlingit and …
The genetic impact of aztec imperialism
In AD 1428, the city‐states of Tenochtitlan, Texcoco, and Tlacopan formed the Triple Alliance, laying the foundations of the Aztec empire. Although it is well documented that the Aztecs annexed numerous polities in the Basin of Mexico over the following years, the demographic consequences of this expansion remain unclear. At the city‐state capital of Xaltocan, 16th century documents suggest that the site's conquest and subsequent incorporation in…
Nondestructive sampling of human skeletal remains yields ancient nuclear and mitochondrial DNA
Museum curators and living communities are sometimes reluctant to permit ancient DNA (aDNA) studies of human skeletal remains because the extraction of aDNA usually requires the destruction of at least some skeletal material. Whether these views stem from a desire to conserve precious materials or an objection to destroying ancestral remains, they limit the potential of aDNA research. To help address concerns about destructive analysis and to min…
Ancient DNA perspectives on American colonization and population history
Ancient DNA (aDNA) analyses have proven to be important tools in understanding human population dispersals, settlement patterns, interactions between prehistoric populations, and the development of regional population histories. Here, we review the published results of sixty-three human populations from throughout the Americas and compare the levels of diversity and geographic patterns of variation in the ancient samples with contemporary genetic…
Opsin gene polymorphism predicts trichromacy in a cathemeral lemur
Recent research has identified polymorphic trichromacy in three diurnal strepsirrhines: Coquerel's sifaka ( Propithecus coquereli ), black and white ruffed lemurs ( Varecia variegata ), and red ruffed lemurs ( V. rubra ). Current hypotheses suggest that the transitions to diurnality experienced by Propithecus and Varecia were necessary precursors to their independent acquisitions of trichromacy. Accordingly, cathemeral lemurs are thought to lack …
An ancient DNA test of a founder effect in Native American ABO blood group frequencies
Anthropologists have assumed that reduced genetic diversity in extant Native Americans is due to a founder effect that occurred during the initial peopling of the Americas. However, low diversity could also be the result of subsequent historical events, such as the population decline following European contact. In this study, we show that autosomal DNA from ancient Native American skeletal remains can be used to investigate the low level of ABO b…
The Science and Business of Genetic Ancestry Testing
Commercially available tests of genetic ancestry have significant scientific limitations, but are serious matters for many test-takers.
Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the Americas
Mitochondrial and Y‐chromosome DNA were analyzed from 10,300‐year‐old human remains excavated from On Your Knees Cave on Prince of Wales Island, Alaska (Site 49‐PET‐408). This individual's mitochondrial DNA (mtDNA) represents the founder haplotype of an additional subhaplogroup of haplogroup D that was brought to the Americas, demonstrating that widely held assumptions about the genetic composition of the earliest Americans are incorrect. The amo…
AAPA Statement on Race and Racism
Race does not provide an accurate representation of human biological variation. It was never accurate in the past, and it remains inaccurate when referencing contemporary human populations. Humans are not divided biologically into distinct continental types or racial genetic clusters. Instead, the Western concept of race must be understood as a classification system that emerged from, and in support of, European colonialism, oppression, and discr…
How Academic Diversity Is Transforming Scientific Knowledge in Biological Anthropology
The genetic impact of aztec imperialism
In AD 1428, the city‐states of Tenochtitlan, Texcoco, and Tlacopan formed the Triple Alliance, laying the foundations of the Aztec empire. Although it is well documented that the Aztecs annexed numerous polities in the Basin of Mexico over the following years, the demographic consequences of this expansion remain unclear. At the city‐state capital of Xaltocan, 16th century documents suggest that the site's conquest and subsequent incorporation in…
Clines Without Classes
This article examines Shiao, Bode, Beyer, and Selvig's (2012) arguments in their article 'The Genomic Challenge to the Social Construction of Race' and finds that their claims are based on fundamentally flawed interpretations of current genetic research. We discuss current genomic and genetic knowledge about human biological variation to demonstrate why and how Shiao et al.'s recommendations for future sociological studies and social policy, base…
Unexpected patterns of mitochondrial DNA variation among Native Americans from the Southeastern United States
Mitochondrial DNA (mtDNA) haplogroups were determined by restriction fragment length polymorphism‐typing for 66 individuals from four southeastern North American populations, and the HVS I portion of the mtDNA control region was sequenced in 48 of these individuals. Although populations from the same geographic region usually exhibit similar haplogroup frequency distributions (Lorenz and Smith [ 1996 ] Am. J. Phys. Anthropol. 101: 307–323; Malhi …
Migration and Social Structure among the Hopewell
For more than a century, archaeologists have studied the cultural and skeletal remains of the prehistoric Native Americans known as the 'Hopewell Moundbuilders.' While many aspects of the Hopewell phenomenon are now well understood, questions still remain about the genetic makeup, burial practices, and social structure of Hopewell communities. To help answer these questions, we extracted mitochondrial DNA (mtDNA) from the skeletal remains of 39 i…
Ancient DNA perspectives on American colonization and population history
Ancient DNA (aDNA) analyses have proven to be important tools in understanding human population dispersals, settlement patterns, interactions between prehistoric populations, and the development of regional population histories. Here, we review the published results of sixty-three human populations from throughout the Americas and compare the levels of diversity and geographic patterns of variation in the ancient samples with contemporary genetic…
An ethical crisis in ancient DNA research
In recent years, the field of paleogenomics has grown into an exciting and rapidly advancing area of scientific inquiry. However, scientific work in this field has far outpaced the discipline's dialogue about research ethics. In particular, Indigenous peoples have argued that the paleogenomics revolution has produced a 'vampire science' that perpetuates biocolonialist traditions of extracting Indigenous bodies and heritage without the consent of,…
Situating Science
Native American Genomics and Population Histories
Studies of Native American genetic diversity and population history have been transformed over the last decade by important developments in anthropological genetics. During this time, researchers have adopted new DNA technologies and computational approaches for analyzing genomic data, and they have become increasingly sensitive to the views of research participants and communities. As new methods are applied to long-standing questions, and as mo…
Chaco Canyon Dig Unearths Ethical Concerns
The fijield of paleogenomics (the study of ancient genomes) is rapidly advancing, with more robust methods of isolating ancient DNA and increasing access to next-generation DNA sequencing technology. As these studies progress, many important ethical issues have emerged that should be considered when ancient Native American remains, whom we refer to as ancestors, are used in research. We highlight a 2017 article by Kennett et al., “Archaeogenomic …
Nondestructive sampling of human skeletal remains yields ancient nuclear and mitochondrial DNA
Museum curators and living communities are sometimes reluctant to permit ancient DNA (aDNA) studies of human skeletal remains because the extraction of aDNA usually requires the destruction of at least some skeletal material. Whether these views stem from a desire to conserve precious materials or an objection to destroying ancestral remains, they limit the potential of aDNA research. To help address concerns about destructive analysis and to min…
An ancient DNA test of a founder effect in Native American ABO blood group frequencies
Anthropologists have assumed that reduced genetic diversity in extant Native Americans is due to a founder effect that occurred during the initial peopling of the Americas. However, low diversity could also be the result of subsequent historical events, such as the population decline following European contact. In this study, we show that autosomal DNA from ancient Native American skeletal remains can be used to investigate the low level of ABO b…
The Archaeology of Commoner Social Memories and Legitimizing Histories
Combating Racial Health Disparities through Medical Education
Despite major public health initiatives, significant disparities persist among racially and ethnically defined groups in the prevalence of disease, access to medical care, quality of medical care, and health outcomes for common causes of morbidity and mortality in the United States. It is critical that we develop new and creative strategies to address such inequities; mitigate the social, environmental, institutional, and genetic determinants of …
Opsin Genes and Visual Ecology in a Nocturnal Folivorous Lemur
Ancient DNA from the S child site in I llinois
Archaeologists have long debated whether rapid cultural change in the archaeological record is due to in situ developments, migration of a new group into the region, or the spread of new cultural practices into an area through existing social networks, with the local peoples adopting and adapting practices from elsewhere as they see fit (acculturation). Researchers have suggested each of these explanations for the major cultural transition that o…
Brief communication
In this study, we explore the geographic and temporal distribution of a unique variant of the O blood group allele called O1v G542A , which has been shown to be shared among Native Americans but is rare in other populations. O1v G542A was previously reported in Native American populations in Mesoamerica and South America, and has been proposed as an ancestry informative marker. We investigated whether this allele is also found in the Tlingit and …
Unexpected patterns of mitochondrial DNA variation among Native Americans from the Southeastern United States
Mitochondrial DNA (mtDNA) haplogroups were determined by restriction fragment length polymorphism‐typing for 66 individuals from four southeastern North American populations, and the HVS I portion of the mtDNA control region was sequenced in 48 of these individuals. Although populations from the same geographic region usually exhibit similar haplogroup frequency distributions (Lorenz and Smith [ 1996 ] Am. J. Phys. Anthropol. 101: 307–323; Malhi …
The Science and Business of Genetic Ancestry Testing
Commercially available tests of genetic ancestry have significant scientific limitations, but are serious matters for many test-takers.
Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the Americas
Mitochondrial and Y‐chromosome DNA were analyzed from 10,300‐year‐old human remains excavated from On Your Knees Cave on Prince of Wales Island, Alaska (Site 49‐PET‐408). This individual's mitochondrial DNA (mtDNA) represents the founder haplotype of an additional subhaplogroup of haplogroup D that was brought to the Americas, demonstrating that widely held assumptions about the genetic composition of the earliest Americans are incorrect. The amo…
Migration and Social Structure among the Hopewell
For more than a century, archaeologists have studied the cultural and skeletal remains of the prehistoric Native Americans known as the 'Hopewell Moundbuilders.' While many aspects of the Hopewell phenomenon are now well understood, questions still remain about the genetic makeup, burial practices, and social structure of Hopewell communities. To help answer these questions, we extracted mitochondrial DNA (mtDNA) from the skeletal remains of 39 i…
An ancient DNA test of a founder effect in Native American ABO blood group frequencies
Anthropologists have assumed that reduced genetic diversity in extant Native Americans is due to a founder effect that occurred during the initial peopling of the Americas. However, low diversity could also be the result of subsequent historical events, such as the population decline following European contact. In this study, we show that autosomal DNA from ancient Native American skeletal remains can be used to investigate the low level of ABO b…
Opsin gene polymorphism predicts trichromacy in a cathemeral lemur
Recent research has identified polymorphic trichromacy in three diurnal strepsirrhines: Coquerel's sifaka ( Propithecus coquereli ), black and white ruffed lemurs ( Varecia variegata ), and red ruffed lemurs ( V. rubra ). Current hypotheses suggest that the transitions to diurnality experienced by Propithecus and Varecia were necessary precursors to their independent acquisitions of trichromacy. Accordingly, cathemeral lemurs are thought to lack …
Ancient DNA perspectives on American colonization and population history
Ancient DNA (aDNA) analyses have proven to be important tools in understanding human population dispersals, settlement patterns, interactions between prehistoric populations, and the development of regional population histories. Here, we review the published results of sixty-three human populations from throughout the Americas and compare the levels of diversity and geographic patterns of variation in the ancient samples with contemporary genetic…
The genetic impact of aztec imperialism
In AD 1428, the city‐states of Tenochtitlan, Texcoco, and Tlacopan formed the Triple Alliance, laying the foundations of the Aztec empire. Although it is well documented that the Aztecs annexed numerous polities in the Basin of Mexico over the following years, the demographic consequences of this expansion remain unclear. At the city‐state capital of Xaltocan, 16th century documents suggest that the site's conquest and subsequent incorporation in…
Nondestructive sampling of human skeletal remains yields ancient nuclear and mitochondrial DNA
Museum curators and living communities are sometimes reluctant to permit ancient DNA (aDNA) studies of human skeletal remains because the extraction of aDNA usually requires the destruction of at least some skeletal material. Whether these views stem from a desire to conserve precious materials or an objection to destroying ancestral remains, they limit the potential of aDNA research. To help address concerns about destructive analysis and to min…
Brief communication
In this study, we explore the geographic and temporal distribution of a unique variant of the O blood group allele called O1v G542A , which has been shown to be shared among Native Americans but is rare in other populations. O1v G542A was previously reported in Native American populations in Mesoamerica and South America, and has been proposed as an ancestry informative marker. We investigated whether this allele is also found in the Tlingit and …
Late Pleistocene Human Skeleton and mtDNA Link Paleoamericans and Modern Native Americans
American Beauty Modern Native American ancestry traces back to an East Asian migration across Beringia. However, some Native American skeletons from the late Pleistocene show phenotypic characteristics more similar to other, more geographically distant, human populations. Chatters et al. (p. 750 ) describe a skeleton with a Paleoamerican phenotype from the eastern Yucatan, dating to approximately 12 to 13 thousand years ago, with a relatively com…
Opsin Genes and Visual Ecology in a Nocturnal Folivorous Lemur
Clines Without Classes
This article examines Shiao, Bode, Beyer, and Selvig's (2012) arguments in their article 'The Genomic Challenge to the Social Construction of Race' and finds that their claims are based on fundamentally flawed interpretations of current genetic research. We discuss current genomic and genetic knowledge about human biological variation to demonstrate why and how Shiao et al.'s recommendations for future sociological studies and social policy, base…
Abstracts ‐ AAPA Presentations
Spanish colonialism had profound genetic effects on native populations in central Mexico. Previous studies have shown that gene flow from Spanish colonists and African slaves introduced new genetic variants into indigenous populations, but the magnitude of this genetic impact likely varied across communities. While Spanish colonists interacted extensively with some indigenous communities, other communities had much less direct contact. Spanish co…
Does Mitochondrial Haplogroup X Indicate Ancient Trans-Atlantic Migration to the Americas? A Critical Re-Evaluation
It might seem strange for an article to focus largely on the history of a single mitochondrial haplogroup in an era when complete genome sequencing is becoming more common. But as recent publicatio
Combating Racial Health Disparities through Medical Education
Despite major public health initiatives, significant disparities persist among racially and ethnically defined groups in the prevalence of disease, access to medical care, quality of medical care, and health outcomes for common causes of morbidity and mortality in the United States. It is critical that we develop new and creative strategies to address such inequities; mitigate the social, environmental, institutional, and genetic determinants of …
Ancient DNA from the S child site in I llinois
Archaeologists have long debated whether rapid cultural change in the archaeological record is due to in situ developments, migration of a new group into the region, or the spread of new cultural practices into an area through existing social networks, with the local peoples adopting and adapting practices from elsewhere as they see fit (acculturation). Researchers have suggested each of these explanations for the major cultural transition that o…
Native American Genomics and Population Histories
Studies of Native American genetic diversity and population history have been transformed over the last decade by important developments in anthropological genetics. During this time, researchers have adopted new DNA technologies and computational approaches for analyzing genomic data, and they have become increasingly sensitive to the views of research participants and communities. As new methods are applied to long-standing questions, and as mo…
The Archaeology of Commoner Social Memories and Legitimizing Histories
Chaco Canyon Dig Unearths Ethical Concerns
The fijield of paleogenomics (the study of ancient genomes) is rapidly advancing, with more robust methods of isolating ancient DNA and increasing access to next-generation DNA sequencing technology. As these studies progress, many important ethical issues have emerged that should be considered when ancient Native American remains, whom we refer to as ancestors, are used in research. We highlight a 2017 article by Kennett et al., “Archaeogenomic …
A framework for enhancing ethical genomic research with Indigenous communities
Integration of genomic technology into healthcare settings establishes new capabilities to predict disease susceptibility and optimize treatment regimes. Yet, Indigenous peoples remain starkly underrepresented in genetic and clinical health research and are unlikely to benefit from such efforts. To foster collaboration with Indigenous communities, we propose six principles for ethical engagement in genomic research: understand existing regulation…
AAPA Statement on Race and Racism
Race does not provide an accurate representation of human biological variation. It was never accurate in the past, and it remains inaccurate when referencing contemporary human populations. Humans are not divided biologically into distinct continental types or racial genetic clusters. Instead, the Western concept of race must be understood as a classification system that emerged from, and in support of, European colonialism, oppression, and discr…
Interpreting and communicating genetic variation in 2019
Situating Science
How Academic Diversity Is Transforming Scientific Knowledge in Biological Anthropology
Biology (22 obras) · Evolutionary biology (16 obras) · Forensic and Genetic Research (16 obras) · Genetics (15 obras) · Sociology (15 obras) · Gene (13 obras) · Genetics (13 obras) · Race, Genetics, and Society (12 obras) · Demography (11 obras) · Geography (11 obras)