Harsha Thirumurthy
Dados Biográficos
| ID | 916401 |
|---|---|
| NOME | Harsha Thirumurthy |
| PRENOMES | Harsha |
| SOBRENOME | Thirumurthy |
| ASSINATURA | THIRUMURTHY H |
| AFILIAÇÕES | University of Pennsylvania |
| ORCID | 0000-0002-3308-7603 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 64 |
| TOTAL DE CITAÇÕES | 81 |
| TOTAL COMO AUTOR | 64 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2010 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 3 |
Systematic dissemination of study findings from local to national stakeholders
Disseminating research findings to potential beneficiaries such as study participants, community members, and stakeholders is a critical component of participatory research. While there is general agreement that dissemination is critical, documented examples of comprehensive dissemination activities are few in the literature. We present a concrete example of a multi-level stakeholder dissemination process from a successful HIV self-testing and li…
Characterising concerns and misinformation shaping global HIV vaccine confidence and demand
BACKGROUND: Demand for a future HIV vaccine, similar to other vaccines, is vulnerable to misinformation. A number of studies have examined HIV vaccine acceptability and demand, but few have systematically explored the specific concerns and misinformation that shape these attitudes. This structured review and content analysis of published and grey literature identifies concerns about the HIV vaccine that might fuel misinformation about the vaccine…
“You could hear their breathing slow down”
High rates of AIDS-related mortality and HIV incidence persist due to delayed antiretroviral therapy (ART) uptake and retention. We qualitatively assessed the feasibility and acceptability of "From Now On" (FNO) - a short video-based psychosocial support intervention to increase ART uptake and improve psychosocial well-being among men newly diagnosed with HIV in South Africa. In-depth interviews were conducted with men who were shown FNO during p…
Motivations for testing and linkage to HIV services following HIV self-testing among fishermen in Kenya
HIV self-testing (HIVST) is a promising strategy to expand testing access for hard-to-reach populations such as Kenyan fishermen. We examined motivations and barriers to HIVST use and linkage to HIV prevention and treatment services (including PrEP or ART), within a social network-based intervention (NCT04772469). We conducted interviews (N = 64) and focus group discussions (N = 4) with fishermen in Siaya County, including 30 “promoters” who dist…
Hazardous alcohol use is associated with sexual behaviors that increase risk for HIV acquisition among fishermen in a high HIV prevalence area of Kenya
Links between hazardous alcohol use and HIV acquisition are well documented, with less known about this relationship among fishermen, a priority group for HIV prevention. We examined associations between hazardous alcohol use and sexual risk behaviors among fishermen in Kenya using 2022 data from 733 fishermen in three Lake Victoria communities. Measures included the AUDIT-C and sexual relationship histories. Logistic regression models assessed a…
Unconditional cash transfers to improve health behaviors among primary care patients
Unconditional cash transfers are a popular poverty reduction approach and may influence behavioral risk factors for chronic disease outcomes through economic and psychological pathways. Few studies have used qualitative interviews to identify the mechanisms through which cash transfers delivered in a health care context might influence the health of people living with chronic diseases in the United States. We conducted a pilot randomized controll…
Understanding HIV Vaccine Misinformation and Vaccine Intentions Among Young Women in South Africa
An effective HIV vaccine could significantly reduce HIV incidence, but demand for future HIV vaccines will be affected by misinformation. We conducted an online survey (March-April 2024) to identify the misinformation claims most likely to deter young women in South Africa (n = 188) from receiving an HIV vaccine. Participants rated HIV-vaccine misinformation as most concerning (i.e. would make them not want to get vaccinated) and least concerning…
Does home-based screening improve hypertension diagnosis, treatment and control? A regression discontinuity analysis in urban India
As part of India’s efforts to expand primary healthcare services, several state governments are implementing or considering home-based hypertension screening programmes to improve population-wide diagnosis and blood pressure (BP) control rates. However, there is limited evidence on the effectiveness of home-based screening programmes in India. Using six waves of population-representative cohort data (N=15574), we estimate the causal effect of a h…
Comparing comprehension of consent document between adolescent girls and caregivers of adolescents in Siaya County, Kenya
Despite their vulnerability, adolescents are often excluded from health research due to ethical concerns about research with minors, especially in low-income regions like Sub-Saharan Africa. We enrolled adolescent girls aged 15–17 years and caregivers of girls of the same age. Using a 25-question Comprehension Score Sheet, we applied a quantitative approach to compare the comprehension of informed consent of 33 adolescent girls and 41 caregivers …
B-Ok
Lack of adherence to antiretroviral therapy (ART) and poor retention in care are significant barriers to ending HIV epidemics. Treatment adherence support effectiveness may be constrained by limited understanding of the benefits of ART. We evaluated a visual and tactile tool, the B-OK Bottles (“B-OK”), that incorporates human-centered design and behavioral economics principles and is designed to change and strengthen mental models about HIV. We e…
Comparing PrEP adherence via objective and self-reported measures among fishermen working on Lake Victoria, Kenya
Fishermen working along Lake Victoria experience high rates of HIV acquisition that can be mitigated by pre-exposure prophylaxis (PrEP), which requires adequate adherence for effective prevention. We evaluated PrEP adherence among Kenyan fishermen using objective metrics and examine non-adherence. Data are from the Owete study (NCT04772469), a cluster randomized-controlled trial using a social network approach among fishermen to increase HIV test…
High mortality among fishermen along the beaches of lake Victoria
The causes of death were varied, underscoring the need for a multi-disease approach to address the health risks in high-risk occupations like fishing. Since HIV is one of several significant health threats to fishermen, efforts to end HIV must also address other life-threatening conditions
Experiences and perceptions of conditional cash incentive provision and cessation among people with HIV for care engagement
CCTs do not appear to exert their effects through motivation, but instead act through creating opportunities for better care engagement. This study helps us better understand the durability of financial incentives for HIV care engagement and support the idea that careful consideration be exercised when implementing incentives for sustainable engagement effects
There is no need to leave the beach to test”
While few fishermen had ever used HIVST, this study found high awareness, positive perceptions, and substantial willingness to use and distribute HIVST to other men. The "promoter" model, with known peers engaged in disseminating HIVST information and test kits, shows promise for engaging men in testing
Money, Medicine, and Motherhood
Improving perinatal engagement in HIV care is critical to prevent disease progression and transmission. In Haiti and other low-resource settings, poverty contributes substantially to poor perinatal HIV outcomes. Cash transfers are a promising intervention that may alleviate poverty and improve perinatal HIV outcomes through economic and psychological pathways. To inform the design of an unconditional cash transfer intervention, we conducted semi-…
Behaviourally-Informed Two-Way Text Messaging to Improve Return to HIV Care in South Africa
One-way text messaging to re-engage people in HIV care has shown promise, but little is known about two-way messaging. We evaluated a behaviourally-informed two-way text messaging intervention to increase re-engagement in care following missed visits. We conducted an individual-level randomised controlled trial between February and March 2023 in Capricorn District, South Africa. Adults aged ≥ 18 years who had missed an ART visit by > 28 days were…
Gaps in Effective HIV Pre-exposure Prophylaxis Screening and Uptake Among Fishermen in Kenya
Despite oral daily HIV pre-exposure prophylaxis (PrEP) effectiveness, uptake remains a challenge. Awareness of one's HIV status and engagement in prevention is essential to interrupting transmission among populations at high risk of HIV. We explored gaps in HIV risk perception, screening, and PrEP uptake among high HIV-risk fishermen living and working along Lake Victoria, Kenya. Data are from the Owete study (NCT04772469), which evaluated the im…
Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use
Economic incentives to promote health behavior change are highly efficacious for substance use disorders as well as increased medication adherence. Knowledge about participants’ experiences with and perceptions of incentives is needed to understand their mechanisms of action and optimize future incentive-based interventions. The Drinkers’ Intervention to Prevent Tuberculosis (DIPT) trial enrolled people with HIV (PWH) in Uganda with latent tuberc…
Applying behavioural economics principles to increase demand for free HIV testing services at private doctor-led clinics in Johannesburg, South Africa
Expanding free HIV testing service (HTS) access to include private clinics could increase testing rates. A donor funded programme, GP Care Cell, offered free HIV testing at selected private doctor-led clinics but uptake was low. We investigated whether HTS demand creation materials that used behavioural economics principles could increase demand for HIV testing at these clinics. We conducted a randomised controlled trial in Johannesburg, South Af…
Jitegemee (rely on yourself)
A savings intervention for and by FSW was highly acceptable and feasible. Involving end-users in the design process is likely to result in greater economic security among FSW and lower engagement in higher risk transactional sex
Mental Bandwidth is Associated with HIV and Viral Suppression Among Low-Income Women in Philadelphia
Behavioral economics research suggests poverty may influence behavior by reducing mental bandwidth, increasing future discounting, and increasing risk aversion. It is plausible these decision-making processes are further impaired in the context of HIV or pregnancy. In this cross-sectional study of 86 low-income women in Philadelphia, HIV was associated with lower mental bandwidth (one of two measures) and lower risk aversion. Pregnancy was not as…
Intergenerational spillover effects of antiretroviral therapy in sub-Saharan Africa
BACKGROUND: Antiretroviral therapy (ART) may influence individuals who do not receive the intervention but who are connected in some way to the person who does. Relatively little is known, however, about the size and scope of, what we term, spillover effects of ART. We explored intergenerational spillover effects of ART in sub-Saharan Africa (SSA) and identified several directions for future research. METHODS: We conducted a scoping review betwee…
Feasibility and preliminary effectiveness of integrating HIV prevention into an adolescent empowerment and livelihood intervention at youth clubs in rural Uganda
The uptake of HIV prevention services is lower among youth than adults in sub-Saharan Africa. Existing youth livelihood trainings offer a potential entry point to HIV prevention services. We determined feasibility and preliminary effectiveness of integrating HIV prevention into youth clubs implementing an empowerment and livelihood for adolescents (ELA) intervention in rural Uganda. Staff conducted community mobilization for youth (15-24 years) o…
Associations Between Ending Supplemental Nutrition Assistance Program Emergency Allotments and Food Insufficiency
This cross-sectional study evaluates associations between changes in Supplemental Nutrition Assistance Program emergency allotments and food insufficiency, a severe form of food insecurity characterized by recent food inadequacy
Routine child immunizations in India during the Covid-19 pandemic
Disruptions in health service delivery and utilization during the COVID-19 pandemic may have caused many children worldwide to not receive vital preventative health services. We investigate the pandemic's effects on routine childhood vaccinations in India, which has the world's largest child immunization program. Using data from the Government of India's health management information system and interrupted time series analyses, we estimate distri…
Wars and child health
Impact of the Kenya Cash Transfer for Orphans and Vulnerable Children on early pregnancy and marriage of adolescent girls
The effects of cash transfer programmes on HIV-related outcomes in 42 countries from 1996 to 2019
Investments in children’s health and the Kenyan cash transfer for orphans and vulnerable children
Child mortality is one of the most pressing global health and policy issues in the developing world. The leading drivers of death-pneumonia, diarrhea and malaria-are preventable and treatable. However, these illnesses are exacerbated by a lack of accessible nutrition, water, basic and preventive health services, and sanitary living conditions-all factors which are more likely to disproportionately impact the poor. We examine whether Kenya's large…
Text Messaging for Improving Antiretroviral Therapy Adherence
Objectives. To assess the effectiveness of Short Message Service (SMS) reminder messages on antiretroviral and cotrimoxazole prophylaxis adherence among HIV-positive youths as well as the relative effectiveness of SMS with and without a response option. Methods. Eligible HIV-positive patients aged 15 to 22 years at 2 HIV clinics in Kampala, Uganda, participated in a year-long parallel individual-randomized controlled trial and were assigned in a …
Economic costs and cost-effectiveness of conditional cash transfers for the uptake of services for the prevention of vertical HIV transmissions in a resource-limited setting
Detailed Geographic Information, Conflict Exposure, and Health Impacts
Examination of facilitators and barriers to home‐based supplemental feeding with ready‐to‐use food for underweight children in western Uganda
Poor complementary feeding practices and low-quality complementary foods are significant causes of growth faltering and child mortality throughout the developing world. Ready-to-use foods (RUF) are energy-dense, lipid-based products that do not require cooking or refrigeration that have been used to prevent and treat malnutrition among vulnerable children. The effectiveness of these products in improving child nutritional status depends on househ…
Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting
OBJECTIVE: There is limited evidence on whether growing mobile phone availability in sub-Saharan Africa can be used to promote high adherence to antiretroviral therapy (ART). This study tested the efficacy of short message service (SMS) reminders on adherence to ART among patients attending a rural clinic in Kenya. DESIGN: A randomized controlled trial of four SMS reminder interventions with 48 weeks of follow-up. METHODS: Four hundred and thirty…
Wars and child health
Health and Labor Supply in the Context of HIV/Aids
Using longitudinal survey data collected in Kenya, this paper estimates the longer-term impacts of antiretroviral therapy (ART) on the labor supply of treated adults and their household members. Building upon previous work in Kenya, data collected from 2004-2006 indicate that early evidence on the short-run impacts of ART tends to be upheld over the long-term as well. The results show that the labor supply response among treated adults occurs rap…
The effects of home-based HIV counseling and testing on HIV/Aids stigma among individuals and community leaders in western Kenya
HIV counseling and testing services play an important role in HIV treatment and prevention efforts in developing countries. Community-wide testing campaigns to detect HIV earlier may additionally impact community knowledge and beliefs about HIV. We conducted a cluster-randomized evaluation of a home-based HIV testing campaign in western Kenya and evaluated the effects of the campaign on community leaders' and members' stigma toward people living …
Exploring the potential for using results-based financing to address non-communicable diseases in low- and middle-income countries
There is potential for the US to have a significant impact on NCDs in LMICs through a comprehensive RBF strategy for global health. RBF mechanisms should be tested for use in NCD programs through pilot programs incorporating robust impact evaluations
Epidemiology and awareness of hypertension in a rural Ugandan community
We found a substantial burden of hypertension in rural Uganda. Awareness and treatment of hypertension is low in this region. Enhanced community-based education and prevention efforts tailored to addressing modifiable factors are needed
The Impact of a National Poverty Reduction Program on the Characteristics of Sex Partners Among Kenyan Adolescents
The Government of Kenya's Cash Transfer Program Reduces the Risk of Sexual Debut among Young People Age 15-25
The aim of this study is to assess whether the Government of Kenya's Cash Transfer for Orphans and Vulnerable Children (Kenya CT-OVC) can reduce the risk of HIV among young people by postponing sexual debut. The program provides an unconditional transfer of US$20 per month directly to the main caregiver in the household. An evaluation of the program was implemented in 2007-2009 in seven districts. Fourteen Locations were randomly assigned to rece…
Exploring the Association of Homicides in Northern Mexico and Healthcare Access for US Residents
Impact of lipid‐based nutrient supplementation ( LNS ) on children's diet adequacy in W estern U ganda
Lipid-based nutrient supplements (LNS) can help treat undernutrition; however, the dietary adequacy of children supplemented with LNS, and household utilisation patterns are not well understood. We assessed diet adequacy and the quality of complementary foods by conducting a diet assessment of 128 Ugandan children, ages 6-59 months, who participated in a 10-week programme for children with moderate acute malnutrition (MAM, defined as weight-for-a…
Impact of the Kenya Cash Transfer for Orphans and Vulnerable Children on early pregnancy and marriage of adolescent girls
Effects of a Large-Scale Unconditional Cash Transfer Program on Mental Health Outcomes of Young People in Kenya
Promoting Partner Testing and Couples Testing through Secondary Distribution of HIV Self-Tests
BACKGROUND: Achieving higher rates of partner HIV testing and couples testing among pregnant and postpartum women in sub-Saharan Africa is essential for the success of combination HIV prevention, including the prevention of mother-to-child transmission. We aimed to determine whether providing multiple HIV self-tests to pregnant and postpartum women for secondary distribution is more effective at promoting partner testing and couples testing than …
Promoting male partner HIV testing and safer sexual decision making through secondary distribution of self-tests by HIV-negative female sex workers and women receiving antenatal and post-partum care i…
Expectations about future health and longevity in Kenyan and Ugandan communities receiving a universal test-and-treat intervention in the SEARCH trial
Expectations about future health and longevity are important determinants of individuals' decisions to invest in physical and human capital. Few population-level studies have measured subjective expectations and examined how they are affected by scale-up of antiretroviral therapy (ART). We assessed these expectations in communities receiving annual HIV testing and universal ART. Longitudinal data on expectations were collected at baseline and one…
How does a national poverty programme influence sexual debut among Kenyan adolescents
Cash transfer programmes have recently emerged as promising interventions for HIV prevention among adolescents in Africa. However, the pathways through which risk reduction occurs are not well understood. We examine data on 1429 adolescents and youth from the Kenya Cash Transfer for Orphans and Vulnerable Children, which has been shown to result in delayed sexual debut among adolescents. We explored three potential mediating pathways: schooling, …
Detailed Geographic Information, Conflict Exposure, and Health Impacts
Prevalence and Predictors of Uncircumcised, Kenyan Men’s Desire for Circumcision for Their Infant Sons
Investments in children’s health and the Kenyan cash transfer for orphans and vulnerable children
Child mortality is one of the most pressing global health and policy issues in the developing world. The leading drivers of death-pneumonia, diarrhea and malaria-are preventable and treatable. However, these illnesses are exacerbated by a lack of accessible nutrition, water, basic and preventive health services, and sanitary living conditions-all factors which are more likely to disproportionately impact the poor. We examine whether Kenya's large…
Text Messaging for Improving Antiretroviral Therapy Adherence
Objectives. To assess the effectiveness of Short Message Service (SMS) reminder messages on antiretroviral and cotrimoxazole prophylaxis adherence among HIV-positive youths as well as the relative effectiveness of SMS with and without a response option. Methods. Eligible HIV-positive patients aged 15 to 22 years at 2 HIV clinics in Kampala, Uganda, participated in a year-long parallel individual-randomized controlled trial and were assigned in a …
Leveraging incentives to increase HIV testing uptake among men
Registered with ClinicalTrials.gov on 08/10/2016, ID: NCT02890459. The first participant was enrolled on 11th April 2016
Men’s Beliefs About the Likelihood of Serodiscordance in Couples with an HIV-Positive Partner
Planning prompts to promote uptake of HIV services among men
INTRODUCTION: Interventions informed by behavioural economics, such as planning prompts, have the potential to increase HIV testing at minimal or no cost. Planning prompts have not been previously evaluated for HIV testing uptake. We conducted a randomised clinical trial to evaluate the effectiveness of low-cost planning prompts to promote HIV testing among men. METHODS: We randomised adult men in rural Ugandan parishes to receive a calendar plan…
HIV retesting and risk behaviors among high-risk, HIV-uninfected adults in Uganda
There are limited data characterizing HIV retesting among high-risk adults in sub-Saharan Africa. From October-December 2018, we distributed recruitment cards offering health evaluations with HIV testing at venues frequented by individuals at-risk of HIV infection in Southwest Uganda. Those who attended were asked about their HIV testing history and risk factors: having >1 sexual partner, an HIV+ partner, STIs, and/or transactional sex. We define…
Medicine (53 obras) · HIV/AIDS Research and Interventions (37 obras) · Environmental health (34 obras) · Public health (27 obras) · Adolescent Sexual and Reproductive Health (25 obras) · Demography (23 obras) · Family medicine (21 obras) · Nursing (21 obras) · Poverty, Education, and Child Welfare (21 obras) · Economics (18 obras)