G Testa
Datos Biográficos
| ID | 97406 |
|---|---|
| NOMBRE | G Testa |
| NOMBRES | G |
| APELLIDO | Testa |
| FIRMA | TESTA G |
| AFILIACIONES | University of Milan |
| ORCID | 0000-0002-9104-0918 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 14 |
| TOTAL DE CITAS | 11 |
| TOTAL COMO AUTOR | 14 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2008 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 2 |
Precision medicine ‘versus’ or ‘for’ public health? Different configurations of precision medicine in relation to the social determinants of health
The role of gene-environment interactions in endocrine-sensitive life stages for shaping mental health
The number of people seeking help for mental illness is increasing across all ages, creating a major burden for individuals, families, and the society. While personalized medicine is advancing in other fields, diagnosis and treatment of mental disorders remain largely symptom-based and fail to capture individual, sex, and gender differences in risk, manifestation, and treatment response. Early signs of illness often go unnoticed due to the lack o…
A qualitative comparison of data infrastructures for Covid-19 health-related data
The COVID-19 pandemic has represented the first global health emergency to be tackled through widespread data collection via a broad array of digital health technologies. Throughout Europe, data infrastructures for the acquisition, processing, and management of COVID-19 data were either implemented ex novo or “repurposed” towards this end. Analysing and comparing these data practices may hold great value to the upcoming European Health Data Space…
Different names for the same thing”? Novelty, expectations, and performative nominalism in personalized and precision medicine
This paper explores the complementary and contrasting uses of the terms ‘personalized medicine’ and ‘precision medicine’ in denotations of a biomedical approach attentive to individual specificities that harnesses genomics and other data-intensive profiling technologies. Drawing on qualitative interviews conducted with biomedical experts in the context of the Precision Medicine Initiative in the United States and the 100,000 Genomes project in th…
Rethinking Human Embryo Research Policies
It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if…
Acting on uncertainty
Exposure to multiple synthetic chemicals is a permanent feature of modern life. Many of these chemicals are suspected to disrupt endocrine systems of humans and animals. Endocrine disrupting chemicals (EDCs) act at very low concentrations and non-linearly, defying mainstream single-substance chemical regulation. Here we provide an analysis of findings from the first phase of the European Horizon2020-funded “EDC-MixRisk” project as a case of conte…
Big Tech platforms in health research
The emergence of a global industry of digital health platforms operated by Big Tech corporations, and its growing entanglements with academic and pharmaceutical research networks, raise pressing questions on the capacity of current data governance models, regulatory and legal frameworks to safeguard the sustainability of the health research ecosystem. In this article, we direct our attention toward the challenges faced by the European General Dat…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
The epigenomic self in personalized medicine
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
Scrutinizing the epigenetics revolution
Epigenetics is one of the most rapidly expanding fields in the life sciences. Its rise is frequently framed as a revolutionary turn that heralds a new epoch both for gene-based epistemology and for the wider discourse on life that pervades knowledge-intensive societies of the molecular age. The fundamentals of this revolution remain however to be scrutinized, and indeed the very contours of what counts as 'epigenetic' are often blurred. This is r…
Consuming genomes
Since 2006 companies in the US have started to offer direct-to-consumer (DTC) genetic testing for a variety of diseases and traits. Recently, the activities of 23andMe and Navigenics, the two leading providers of DTC genetic services, have come under the scrutiny of various regulators and institutions, including the Food and Drug Administration (FDA) and the House Committee on Energy and Commerce and, in 2008, the California and New York Departme…
Naked Genes
The molecular life sciences are making visible what was once invisible. Yet the more we learn about our own biology, the less we are able to fit this knowledge into an integrated whole. Life is divided into new sub-units and reassembled into new forms: from genes to clones, from embryonic stages to the building-blocks of synthetic biology. Extracted from their scientific and social contexts, these new entities become not only visible but indeed n…
Stem Cells through Stem Beliefs
In the last decade human embryonic stem cells (hESCs) have emerged as prominent scientific and political objects. Their potential for regenerative medicine and the intersection with early human life spurred both great excitement and considerable ethical worries. Partially as a response to this controversy, the search for ethically unproblematic sources of hESCs became a priority. This paper analyses two paradigmatic examples of this search that e…
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
Stem Cells through Stem Beliefs
In the last decade human embryonic stem cells (hESCs) have emerged as prominent scientific and political objects. Their potential for regenerative medicine and the intersection with early human life spurred both great excitement and considerable ethical worries. Partially as a response to this controversy, the search for ethically unproblematic sources of hESCs became a priority. This paper analyses two paradigmatic examples of this search that e…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
A qualitative comparison of data infrastructures for Covid-19 health-related data
The COVID-19 pandemic has represented the first global health emergency to be tackled through widespread data collection via a broad array of digital health technologies. Throughout Europe, data infrastructures for the acquisition, processing, and management of COVID-19 data were either implemented ex novo or “repurposed” towards this end. Analysing and comparing these data practices may hold great value to the upcoming European Health Data Space…
Different names for the same thing”? Novelty, expectations, and performative nominalism in personalized and precision medicine
This paper explores the complementary and contrasting uses of the terms ‘personalized medicine’ and ‘precision medicine’ in denotations of a biomedical approach attentive to individual specificities that harnesses genomics and other data-intensive profiling technologies. Drawing on qualitative interviews conducted with biomedical experts in the context of the Precision Medicine Initiative in the United States and the 100,000 Genomes project in th…
Big Tech platforms in health research
The emergence of a global industry of digital health platforms operated by Big Tech corporations, and its growing entanglements with academic and pharmaceutical research networks, raise pressing questions on the capacity of current data governance models, regulatory and legal frameworks to safeguard the sustainability of the health research ecosystem. In this article, we direct our attention toward the challenges faced by the European General Dat…
Stem Cells through Stem Beliefs
In the last decade human embryonic stem cells (hESCs) have emerged as prominent scientific and political objects. Their potential for regenerative medicine and the intersection with early human life spurred both great excitement and considerable ethical worries. Partially as a response to this controversy, the search for ethically unproblematic sources of hESCs became a priority. This paper analyses two paradigmatic examples of this search that e…
Naked Genes
The molecular life sciences are making visible what was once invisible. Yet the more we learn about our own biology, the less we are able to fit this knowledge into an integrated whole. Life is divided into new sub-units and reassembled into new forms: from genes to clones, from embryonic stages to the building-blocks of synthetic biology. Extracted from their scientific and social contexts, these new entities become not only visible but indeed n…
Consuming genomes
Since 2006 companies in the US have started to offer direct-to-consumer (DTC) genetic testing for a variety of diseases and traits. Recently, the activities of 23andMe and Navigenics, the two leading providers of DTC genetic services, have come under the scrutiny of various regulators and institutions, including the Food and Drug Administration (FDA) and the House Committee on Energy and Commerce and, in 2008, the California and New York Departme…
Scrutinizing the epigenetics revolution
Epigenetics is one of the most rapidly expanding fields in the life sciences. Its rise is frequently framed as a revolutionary turn that heralds a new epoch both for gene-based epistemology and for the wider discourse on life that pervades knowledge-intensive societies of the molecular age. The fundamentals of this revolution remain however to be scrutinized, and indeed the very contours of what counts as 'epigenetic' are often blurred. This is r…
The epigenomic self in personalized medicine
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
Rethinking Human Embryo Research Policies
It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if…
Acting on uncertainty
Exposure to multiple synthetic chemicals is a permanent feature of modern life. Many of these chemicals are suspected to disrupt endocrine systems of humans and animals. Endocrine disrupting chemicals (EDCs) act at very low concentrations and non-linearly, defying mainstream single-substance chemical regulation. Here we provide an analysis of findings from the first phase of the European Horizon2020-funded “EDC-MixRisk” project as a case of conte…
Big Tech platforms in health research
The emergence of a global industry of digital health platforms operated by Big Tech corporations, and its growing entanglements with academic and pharmaceutical research networks, raise pressing questions on the capacity of current data governance models, regulatory and legal frameworks to safeguard the sustainability of the health research ecosystem. In this article, we direct our attention toward the challenges faced by the European General Dat…
Different names for the same thing”? Novelty, expectations, and performative nominalism in personalized and precision medicine
This paper explores the complementary and contrasting uses of the terms ‘personalized medicine’ and ‘precision medicine’ in denotations of a biomedical approach attentive to individual specificities that harnesses genomics and other data-intensive profiling technologies. Drawing on qualitative interviews conducted with biomedical experts in the context of the Precision Medicine Initiative in the United States and the 100,000 Genomes project in th…
Precision medicine ‘versus’ or ‘for’ public health? Different configurations of precision medicine in relation to the social determinants of health
The role of gene-environment interactions in endocrine-sensitive life stages for shaping mental health
The number of people seeking help for mental illness is increasing across all ages, creating a major burden for individuals, families, and the society. While personalized medicine is advancing in other fields, diagnosis and treatment of mental disorders remain largely symptom-based and fail to capture individual, sex, and gender differences in risk, manifestation, and treatment response. Early signs of illness often go unnoticed due to the lack o…
A qualitative comparison of data infrastructures for Covid-19 health-related data
The COVID-19 pandemic has represented the first global health emergency to be tackled through widespread data collection via a broad array of digital health technologies. Throughout Europe, data infrastructures for the acquisition, processing, and management of COVID-19 data were either implemented ex novo or “repurposed” towards this end. Analysing and comparing these data practices may hold great value to the upcoming European Health Data Space…
Political science (10 obras) · Law (9 obras) · Sociology (9 obras) · Biology (7 obras) · Politics (5 obras) · Business (4 obras) · Computer Science (4 obras) · Environmental ethics (4 obras) · Epistemology (4 obras) · Public relations (4 obras)