Virginia Ramallo
Biographic Data
| ID | 97617 |
|---|---|
| NAME | Virginia Ramallo |
| GIVEN NAMES | Virginia |
| FAMILY NAME | Ramallo |
| SIGNATURE | RAMALLO V |
| AFFILIATIONS | Centro Científico Tecnológico Patagónico |
| ORCID | 0000-0002-7856-4856 |
| VERIFIED | Yes |
| TOTAL WORKS | 22 |
| TOTAL CITATIONS | 28 |
| WORKS AS AUTHOR | 22 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 2 |
Volga German surnames and Alzheimer’s disease in Argentina
The N141I variant (PSEN1 gene) is associated with familial forms of early-onset Alzheimer’s disease (AD) in descendants of Volga Germans, whose migration to Argentina is well documented. As a proxy for geographic origin, surnames can be a valuable tool in population studies. The 2015 Argentine Electoral Registry provided geographic data for 30,530,194 individuals, including 326,922 with Volga German surnames. Between 2005 and 2017, the Ministry o…
Influencia de variables genéticas y socio-ambientales en el exceso de peso en una muestra de la población de Puerto Madryn, Argentina
En Argentina, el exceso de peso aumentó continuamente desde el 2005 hasta el presente. Los factores con probada relación con el exceso de peso son socio-ambientales y genéticos. Entre estos últimos, el gen FTO es el más estudiado. El objetivo de este trabajo fue analizar la relación entre dos marcadores del gen FTO (rs9939609 y rs11075997) y variables socio-ambientales con el estado nutricional en una muestra de 155 personas de Puerto Madryn, Chu…
Mapping spatial morbidity patterns for bronchiolitis related to socioeconomic estimators
OBJECTIVES: To describe the frequency of hospitalizations of infants under 1 year of age with bronchiolitis in Puerto Madryn, Argentina, and to study the spatial distribution of cases throughout the city in relation to socioeconomic indicators. To visualize and better understand the underlying processes behind the local manifestation of the disease by creating a vulnerability map of the city. METHODS: We performed a cross-sectional study of all p…
Disentangling Signatures of Selection Before and After European Colonization in Latin Americans
Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups. Although classical and recent work have shown that studying admixture can yield novel historical insights, the extent to which this process contributed to adaptation remains underexplored. Here, we introduce a novel statistical model, specific to admixed populations, that identifies loci under selectio…
Antropología Biológica
An invincible memory
Several studies have shown that the Brazilian Northeast is a region with high rates of inbreeding as well as a high incidence of autosomal recessive diseases. The elaboration of public health policies focused on the epidemiological surveillance of congenital anomalies and rare genetic diseases in this region is urgently needed. However, the vast territory, socio-demographic heterogeneity, economic difficulties and low number of professionals with…
Linajes paternos autóctonos de Gran Chaco analizados con microsatélites
El Gran Chaco es uno de los biomas de las Tierras Bajas sudamericanas más recientemente poblados por los seres humanos, ha mantenido su diversidad etnolingüística y muestra evidencias de la existencia de contactos interétnicos. El objetivo de este trabajo es reconocer estructuración genética en la fracción nativa de los linajes paternos en las poblaciones chaqueñas, para lo cual se analizaron 116 individuos de poblaciones wichi, toba, chorote y m…
Body shape
OBJECTIVES: The diagnosis and treatment of obesity are usually based on traditional anthropometric variables including weight, height, and several body perimeters. Here we present a three-dimensional (3D) image-based computational approach aimed to capture the distribution of abdominal adipose tissue as an aspect of shape rather than a relationship among classical anthropometric measures. METHODS: A morphometric approach based on landmarks and se…
Continental Origin for Q Haplogroup Patrilineages in Argentina and Paraguay
Haplogroup Q originated in Eurasia around 30,000 years ago. It is present in Y-chromosomes from Asia and Europe at rather low frequencies. Since America is undoubtedly one of the continents where this haplogroup is highly represented, it has been defined as one of the founding haplogroups. Its M3 clade has been early described as the most frequent, with pan-American representation. However, it was also possible to find several other haplogroup Q …
Origen étnico y ancestría genética, ¿qué lugar tienen en la práctica médica en Argentina
La investigación biomédica está contemplando cada vez más la ancestría genética de las poblaciones, con vistas a potenciales aplicaciones en la prevención sanitaria y en el tratamiento de dolencias población- específicas. Los objetivos fueron indagar sobre la formación en genética, universitaria y posuniversitaria, de médicos/as del país, y relacionarlo con la manera de abordar conceptos de genética médica poblacional en la práctica clínica. Se e…
Obesity, genomic ancestry, and socioeconomic variables in Latin American mestizos
The proportion of obesity was heavily dependent on the index and the population. Genomic ancestry has a significant influence on the anthropometric measurements, especially on central adiposity. As a whole, we detected a large interpopulation variation that suggests that better approaches to overweight and obesity phenotypes are needed in order to obtain more precise reference values
Relación entre tratamiento hormonal, cirugía-ortodoncia maxilofacial, traumatismos y malformaciones craneofaciales y la asimetría fluctuante
En este trabajo se evalúa la relación entre la asimetría fluctuante facial (AFF) y los tratamientos hormonales, cirugías maxilofaciales, ortodoncia, traumatismos y malformaciones. En el marco del proyecto CANDELA, se tomaron cinco fotografías faciales de 3162 voluntarios entre los 18 y 85 años. Por fotogrametría se colocaron 34 landmarks o puntos en 3D y mediante el método Procrustes ANOVA se obtuvieron valores individuales de asimetría fluctuant…
Isonymic Relations in the Bolivia-Argentina Border Region
When migrating, people carry their cultural and genetic history, changing both the transmitting and the receiving populations. This phenomenon changes the structure of the population of a country. The question is how to analyze the impact on the border region. A demographic and geopolitical analysis of borders requires an interdisciplinary approach. An isonymic analysis can be a useful tool. Surnames are part of cultural history, sociocultural fe…
Facial asymmetry and genetic ancestry in L atin A merican admixed populations
Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of both asymmetry types is far from being completely known. The analysis of facial asymmetries in admixed individuals can be of help to characterize the impact of a genome's heterozygosity on the developmental basis of both fluctua…
Random inbreeding, isonymy, and population isolates in Argentina
Linajes paternos del Gran Chaco, un abordaje desde el ADN
La región no recombinante del cromosoma Y ha sido exitosamente utilizada para reconocer la estructura genética de los linajes paternos de poblaciones humanas. Este trabajo se integra al proyecto multidisciplinario “De las historias étnicas a la prehistoria en el Gran Chaco”, involucra el estudio de individuos de diversa filiación étnica y se propone reconocer la estructuración en la fracción nativa de los linajes paternos. Tal información dará cu…
Spatial and temporal analysis of infant mortality from congenital malformations in Brazil (1996–2010)
Brief communication
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
Demographic expansions in South America
Native Americans are characterized by specific and unique patterns of genetic and cultural/linguistic diversities, and this information has been used to understand patterns of geographic dispersion, and the relationship between these peoples. Particularly interesting are the Tupi and Je speaker dispersions. At present, a large number of individuals speak languages of these two stocks; for instance, Tupi‐Guarani is one of the official languages in…
Distribution of Y‐chromosome q lineages in native americans
Objectives: This investigation was performed to identify and evaluate the distribution of all 15 Y‐chromosome lineages belonging to the Q clade in a sample of natives from South America. Methods: One hundred and forty‐eight individuals from 20 Native American populations, as well as 24 Asian samples including Eskimos, were tested with 18 biallelic loci that can identify all currently known lineages of the Y‐Chromosome Q clade. Sequencing was perf…
Brief communication
We analyzed 21 paragroup Q* Y chromosomes from South American aboriginal and urban populations. Our aims were to evaluate the phylogenetic status, geographic distribution, and genetic diversity in these groups of chromosomes and compare the degree of genetic variation in relation to Q1a3a haplotypes. All Q* chromosomes from our series and five samples from North American Q* presented the derivate state for M346, that is present upstream to M3, an…
Linajes masculinos y su diversidad en comunidades Wichí de Formosa
Durante el año 2005, se realizaron dos viajes de campaña a comunidades Wichí cercanas a las localidades de Ingeniero Juárez y Laguna Yema (provincia de Formosa, Argentina), como parte del proyecto multidisciplinario "De las historias étnicas a la prehistoria en el Gran Chaco". Partiendo del planteo metodológico de unidad poblacional, se obtuvieron datos genéticos en 93 muestras utilizando marcadores binarios y microsatélites del cromosoma Y, dete…
Brief communication
We analyzed 21 paragroup Q* Y chromosomes from South American aboriginal and urban populations. Our aims were to evaluate the phylogenetic status, geographic distribution, and genetic diversity in these groups of chromosomes and compare the degree of genetic variation in relation to Q1a3a haplotypes. All Q* chromosomes from our series and five samples from North American Q* presented the derivate state for M346, that is present upstream to M3, an…
Demographic expansions in South America
Native Americans are characterized by specific and unique patterns of genetic and cultural/linguistic diversities, and this information has been used to understand patterns of geographic dispersion, and the relationship between these peoples. Particularly interesting are the Tupi and Je speaker dispersions. At present, a large number of individuals speak languages of these two stocks; for instance, Tupi‐Guarani is one of the official languages in…
Continental Origin for Q Haplogroup Patrilineages in Argentina and Paraguay
Haplogroup Q originated in Eurasia around 30,000 years ago. It is present in Y-chromosomes from Asia and Europe at rather low frequencies. Since America is undoubtedly one of the continents where this haplogroup is highly represented, it has been defined as one of the founding haplogroups. Its M3 clade has been early described as the most frequent, with pan-American representation. However, it was also possible to find several other haplogroup Q …
Relación entre tratamiento hormonal, cirugía-ortodoncia maxilofacial, traumatismos y malformaciones craneofaciales y la asimetría fluctuante
En este trabajo se evalúa la relación entre la asimetría fluctuante facial (AFF) y los tratamientos hormonales, cirugías maxilofaciales, ortodoncia, traumatismos y malformaciones. En el marco del proyecto CANDELA, se tomaron cinco fotografías faciales de 3162 voluntarios entre los 18 y 85 años. Por fotogrametría se colocaron 34 landmarks o puntos en 3D y mediante el método Procrustes ANOVA se obtuvieron valores individuales de asimetría fluctuant…
Isonymic Relations in the Bolivia-Argentina Border Region
When migrating, people carry their cultural and genetic history, changing both the transmitting and the receiving populations. This phenomenon changes the structure of the population of a country. The question is how to analyze the impact on the border region. A demographic and geopolitical analysis of borders requires an interdisciplinary approach. An isonymic analysis can be a useful tool. Surnames are part of cultural history, sociocultural fe…
Facial asymmetry and genetic ancestry in L atin A merican admixed populations
Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of both asymmetry types is far from being completely known. The analysis of facial asymmetries in admixed individuals can be of help to characterize the impact of a genome's heterozygosity on the developmental basis of both fluctua…
Linajes paternos del Gran Chaco, un abordaje desde el ADN
La región no recombinante del cromosoma Y ha sido exitosamente utilizada para reconocer la estructura genética de los linajes paternos de poblaciones humanas. Este trabajo se integra al proyecto multidisciplinario “De las historias étnicas a la prehistoria en el Gran Chaco”, involucra el estudio de individuos de diversa filiación étnica y se propone reconocer la estructuración en la fracción nativa de los linajes paternos. Tal información dará cu…
Brief communication
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
Brief communication
We analyzed 21 paragroup Q* Y chromosomes from South American aboriginal and urban populations. Our aims were to evaluate the phylogenetic status, geographic distribution, and genetic diversity in these groups of chromosomes and compare the degree of genetic variation in relation to Q1a3a haplotypes. All Q* chromosomes from our series and five samples from North American Q* presented the derivate state for M346, that is present upstream to M3, an…
Linajes masculinos y su diversidad en comunidades Wichí de Formosa
Durante el año 2005, se realizaron dos viajes de campaña a comunidades Wichí cercanas a las localidades de Ingeniero Juárez y Laguna Yema (provincia de Formosa, Argentina), como parte del proyecto multidisciplinario "De las historias étnicas a la prehistoria en el Gran Chaco". Partiendo del planteo metodológico de unidad poblacional, se obtuvieron datos genéticos en 93 muestras utilizando marcadores binarios y microsatélites del cromosoma Y, dete…
Distribution of Y‐chromosome q lineages in native americans
Objectives: This investigation was performed to identify and evaluate the distribution of all 15 Y‐chromosome lineages belonging to the Q clade in a sample of natives from South America. Methods: One hundred and forty‐eight individuals from 20 Native American populations, as well as 24 Asian samples including Eskimos, were tested with 18 biallelic loci that can identify all currently known lineages of the Y‐Chromosome Q clade. Sequencing was perf…
Spatial and temporal analysis of infant mortality from congenital malformations in Brazil (1996–2010)
Brief communication
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
Demographic expansions in South America
Native Americans are characterized by specific and unique patterns of genetic and cultural/linguistic diversities, and this information has been used to understand patterns of geographic dispersion, and the relationship between these peoples. Particularly interesting are the Tupi and Je speaker dispersions. At present, a large number of individuals speak languages of these two stocks; for instance, Tupi‐Guarani is one of the official languages in…
Random inbreeding, isonymy, and population isolates in Argentina
Linajes paternos del Gran Chaco, un abordaje desde el ADN
La región no recombinante del cromosoma Y ha sido exitosamente utilizada para reconocer la estructura genética de los linajes paternos de poblaciones humanas. Este trabajo se integra al proyecto multidisciplinario “De las historias étnicas a la prehistoria en el Gran Chaco”, involucra el estudio de individuos de diversa filiación étnica y se propone reconocer la estructuración en la fracción nativa de los linajes paternos. Tal información dará cu…
Facial asymmetry and genetic ancestry in L atin A merican admixed populations
Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of both asymmetry types is far from being completely known. The analysis of facial asymmetries in admixed individuals can be of help to characterize the impact of a genome's heterozygosity on the developmental basis of both fluctua…
Isonymic Relations in the Bolivia-Argentina Border Region
When migrating, people carry their cultural and genetic history, changing both the transmitting and the receiving populations. This phenomenon changes the structure of the population of a country. The question is how to analyze the impact on the border region. A demographic and geopolitical analysis of borders requires an interdisciplinary approach. An isonymic analysis can be a useful tool. Surnames are part of cultural history, sociocultural fe…
Relación entre tratamiento hormonal, cirugía-ortodoncia maxilofacial, traumatismos y malformaciones craneofaciales y la asimetría fluctuante
En este trabajo se evalúa la relación entre la asimetría fluctuante facial (AFF) y los tratamientos hormonales, cirugías maxilofaciales, ortodoncia, traumatismos y malformaciones. En el marco del proyecto CANDELA, se tomaron cinco fotografías faciales de 3162 voluntarios entre los 18 y 85 años. Por fotogrametría se colocaron 34 landmarks o puntos en 3D y mediante el método Procrustes ANOVA se obtuvieron valores individuales de asimetría fluctuant…
Obesity, genomic ancestry, and socioeconomic variables in Latin American mestizos
The proportion of obesity was heavily dependent on the index and the population. Genomic ancestry has a significant influence on the anthropometric measurements, especially on central adiposity. As a whole, we detected a large interpopulation variation that suggests that better approaches to overweight and obesity phenotypes are needed in order to obtain more precise reference values
Linajes paternos autóctonos de Gran Chaco analizados con microsatélites
El Gran Chaco es uno de los biomas de las Tierras Bajas sudamericanas más recientemente poblados por los seres humanos, ha mantenido su diversidad etnolingüística y muestra evidencias de la existencia de contactos interétnicos. El objetivo de este trabajo es reconocer estructuración genética en la fracción nativa de los linajes paternos en las poblaciones chaqueñas, para lo cual se analizaron 116 individuos de poblaciones wichi, toba, chorote y m…
Body shape
OBJECTIVES: The diagnosis and treatment of obesity are usually based on traditional anthropometric variables including weight, height, and several body perimeters. Here we present a three-dimensional (3D) image-based computational approach aimed to capture the distribution of abdominal adipose tissue as an aspect of shape rather than a relationship among classical anthropometric measures. METHODS: A morphometric approach based on landmarks and se…
Continental Origin for Q Haplogroup Patrilineages in Argentina and Paraguay
Haplogroup Q originated in Eurasia around 30,000 years ago. It is present in Y-chromosomes from Asia and Europe at rather low frequencies. Since America is undoubtedly one of the continents where this haplogroup is highly represented, it has been defined as one of the founding haplogroups. Its M3 clade has been early described as the most frequent, with pan-American representation. However, it was also possible to find several other haplogroup Q …
Origen étnico y ancestría genética, ¿qué lugar tienen en la práctica médica en Argentina
La investigación biomédica está contemplando cada vez más la ancestría genética de las poblaciones, con vistas a potenciales aplicaciones en la prevención sanitaria y en el tratamiento de dolencias población- específicas. Los objetivos fueron indagar sobre la formación en genética, universitaria y posuniversitaria, de médicos/as del país, y relacionarlo con la manera de abordar conceptos de genética médica poblacional en la práctica clínica. Se e…
An invincible memory
Several studies have shown that the Brazilian Northeast is a region with high rates of inbreeding as well as a high incidence of autosomal recessive diseases. The elaboration of public health policies focused on the epidemiological surveillance of congenital anomalies and rare genetic diseases in this region is urgently needed. However, the vast territory, socio-demographic heterogeneity, economic difficulties and low number of professionals with…
Disentangling Signatures of Selection Before and After European Colonization in Latin Americans
Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups. Although classical and recent work have shown that studying admixture can yield novel historical insights, the extent to which this process contributed to adaptation remains underexplored. Here, we introduce a novel statistical model, specific to admixed populations, that identifies loci under selectio…
Antropología Biológica
Mapping spatial morbidity patterns for bronchiolitis related to socioeconomic estimators
OBJECTIVES: To describe the frequency of hospitalizations of infants under 1 year of age with bronchiolitis in Puerto Madryn, Argentina, and to study the spatial distribution of cases throughout the city in relation to socioeconomic indicators. To visualize and better understand the underlying processes behind the local manifestation of the disease by creating a vulnerability map of the city. METHODS: We performed a cross-sectional study of all p…
Volga German surnames and Alzheimer’s disease in Argentina
The N141I variant (PSEN1 gene) is associated with familial forms of early-onset Alzheimer’s disease (AD) in descendants of Volga Germans, whose migration to Argentina is well documented. As a proxy for geographic origin, surnames can be a valuable tool in population studies. The 2015 Argentine Electoral Registry provided geographic data for 30,530,194 individuals, including 326,922 with Volga German surnames. Between 2005 and 2017, the Ministry o…
Influencia de variables genéticas y socio-ambientales en el exceso de peso en una muestra de la población de Puerto Madryn, Argentina
En Argentina, el exceso de peso aumentó continuamente desde el 2005 hasta el presente. Los factores con probada relación con el exceso de peso son socio-ambientales y genéticos. Entre estos últimos, el gen FTO es el más estudiado. El objetivo de este trabajo fue analizar la relación entre dos marcadores del gen FTO (rs9939609 y rs11075997) y variables socio-ambientales con el estado nutricional en una muestra de 155 personas de Puerto Madryn, Chu…
Geography (12 works) · Biology (10 works) · Demography (9 works) · Medicine (8 works) · Population (8 works) · Sociology (8 works) · Art (7 works) · Forensic and Genetic Research (7 works) · Genetics (7 works) · Evolutionary biology (6 works)