Anne C Stone
Biographic Data
| ID | 99092 |
|---|---|
| NAME | Anne C Stone |
| GIVEN NAMES | Anne C |
| FAMILY NAME | Stone |
| SIGNATURE | STONE A C |
| AFFILIATIONS | Arizona State University |
| ORCID | 0000-0001-8021-8314 |
| VERIFIED | Yes |
| TOTAL WORKS | 34 |
| TOTAL CITATIONS | 230 |
| AUTHOR COUNT | 34 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1993 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 9 |
Understanding Turkey Management in the Mimbres Valley of Southwestern New Mexico Using Ancient Mitochondrial DNA and Stable Isotopes
In the US Southwest and Northwest Mexico, people and turkeys (Meleagris gallopavo) have had a reciprocal relationship for millennia; turkeys supplied feathers, meat, and other resources, whereas people provided food, shelter, and care. To investigate how turkeys fit within subsistence, economic production, sociopolitical organization, and religious and ritual practice in the Mimbres Valley of southwestern New Mexico, we report on genetic (mtDNA) …
Twenty-first century bioarchaeology: Taking stock and moving forward
This article presents outcomes from a Workshop entitled "Bioarchaeology: Taking Stock and Moving Forward," which was held at Arizona State University (ASU) on March 6-8, 2020. Funded by the National Science Foundation (NSF), the School of Human Evolution and Social Change (ASU), and the Center for Bioarchaeological Research (CBR, ASU), the Workshop's overall goal was to explore reasons why research proposals submitted by bioarchaeologists, both g…
Identification of the geographic origins of people buried in the cemetery of the Salesian Mission of Tierra del Fuego through the analyses of mtDNA and stable isotopes
Intraspecific and interspecific investigations of skeletal DNA methylation and femur morphology in primates
OBJECTIVES: Epigenetic mechanisms influence the development and maintenance of complex phenotypes and may also contribute to the evolution of species-specific phenotypes. With respect to skeletal traits, little is known about the gene regulation underlying these hard tissues or how tissue-specific patterns are associated with bone morphology or vary among species. To begin exploring these topics, this study evaluates one epigenetic mechanism, DNA…
Advancing the understanding of treponemal disease in the past and present
Syphilis was perceived to be a new disease in Europe in the late 15th century, igniting a debate about its origin that continues today in anthropological, historical, and medical circles. We move beyond this age‐old debate using an interdisciplinary approach that tackles broader questions to advance the understanding of treponemal infection (syphilis, yaws, bejel, and pinta). How did the causative organism(s) and humans co‐evolve? How did the rel…
The efficacy of whole human genome capture on ancient dental calculus and dentin
OBJECTIVES: Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques. MATERIALS AND METHODS: Total DNA extracted from 24 pai…
Comparison of two ancient DNA extraction protocols for skeletal remains from tropical environments
OBJECTIVES: The tropics harbor a large part of the world's biodiversity and have a long history of human habitation. However, paleogenomics research in these climates has been constrained so far by poor ancient DNA yields. Here we compare the performance of two DNA extraction methods on ancient samples of teeth and petrous portions excavated from tropical and semi-tropical sites in Tanzania, Mexico, and Puerto Rico (N = 12). MATERIALS AND METHODS…
Application of PE‐Radseq to the study of genomic diversity and divergence of two Brazilian marmoset species ( Callithrix jacchus and C. penicillata )
Callithrix jacchus and C. penicillata are among the smallest anthropoid primates, are highly specialized tree gougers, and largely occupy Brazil's most extreme, semi-arid biomes. However, the underlying genomic factors that underpin the evolution of these species and their unique traits are under-investigated. Additionally, exotic populations of these two species are widely established throughout Brazil and hybridize with threatened native conger…
Determining the population affinity of an unprovenienced human skull for repatriation
An archaeological assessment was carried out on an unprovenienced human skull recovered in eastern Idaho, exhibiting cranial deformation and peri-mortem application of a red pigment. A combination of scanning electron microscopy (SEM), X-ray fluorescence (XRF), and energy-dispersive X-ray spectroscopy (EDS) identified the major and trace elements present in the red pigment as natural cinnabar. Carbon and oxygen stable isotopes from teeth and bone…
Phylogeny of the jacchus group of Callithrix marmosets based on complete mitochondrial genomes
OBJECTIVES: Two subgroups make up the marmoset genus Callithrix. The "aurita" group is composed of two species, whereas evolutionary relationships among the four species of the "jacchus" group remain unclear. To uncover these relationships, we first sequenced mitochondrial genomes for C. kuhlii and C. penicillata to complement data available for congeners. We then constructed a phylogenetic tree based on mtDNA heavy chain protein coding genes fro…
Facing the facts: The Runx2 gene is associated with variation in facial morphology in primates
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
Ancient pathogen genomics: Insights Into Timing and Adaptation
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Population Genetic Structure of Traditional Populations in the Peruvian Central Andes and Implications for South American Population History
Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east contrast in patterns of population genetic variation is typically attributed to large-scale phe…
Hybridization effects and genetic diversity of the common and black‐tufted marmoset ( C allithrix jacchus and C allithrix penicillata ) mitochondrial control region
Hybridization is continually documented in primates, but effects of natural and anthropogenic hybridization on biodiversity are still unclear and differentiating between these contexts remains challenging in regards to primate evolution and conservation. Here, we examine hybridization effects on the mitochondrial DNA (mtDNA) control region of Callithrix marmosets, which provide a unique glimpse into interspecific mating under distinct anthropogen…
AAPA Presentation Schedule
The history of infectious disease in humans (and to a lesser extent other primates) has been studied from different perspectives including those of bioarchaeology, medical history, and evolutionary genetics. Technical advances in nucleotide sequencing as well as in the ability to obtain genetic material from difficult sources (such as feces and ancient materials) have enhanced our ability to examine both ancient pathogens and pathogens that are d…
An anthropological genetic perspective on creolization in the anglophone caribbean
Variable socio‐cultural influences developed in the colonial Caribbean as a result of competing European hegemonic rule. In this study, we examine how colonial regulations regarding social hierarchies and mate choice worked to influence the genetic landscape of contemporary African Caribbean populations. To this end, 420 individuals from Dominica, Grenada, St. Kitts, St. Lucia, St. Thomas, St. Vincent, Jamaica, and Trinidad were genotyped for 105…
Tuberculosis on the north coast of Peru: Skeletal and molecular paleopathology of late pre-Hispanic and postcontact mycobacterial disease
Deficiencies and challenges in the study of ancient tuberculosis DNA
Tuberculosis and leprosy in perspective
Two of humankind's most socially and psychologically devastating diseases, tuberculosis and leprosy, have been the subject of intensive paleopathological research due to their antiquity, a presumed association with human settlement and subsistence patterns, and their propensity to leave characteristic lesions on skeletal and mummified remains. Despite a long history of medical research and the development of effective chemotherapy, these diseases…
Diet and the evolution of human amylase gene copy number variation
Mitochondrial DNA and Peopling of South America
The initial peopling of South America is largely unresolved, in part because of the unique distribution of genetic diversity in native South Americans. On average, genetic diversity estimated within Andean populations is higher than that estimated within Amazonian populations. Yet there is less genetic differentiation estimated among Andean populations than estimated among Amazonian populations. One hypothesis is that this pattern is a product of…
Ancient DNA and Genetic Continuity in the South Central Andes
Alternative models of residential mobility have been proposed to explain the development and spread of Tiwanaku influ ence across the south central Andes. Within the Osmore drainage, the rich Moquegua Valley has been hypothesized as the site of a significant colonization event (or events) whereby both the natural and human landscape was transformed and integrated into the expansive Tiwanaku state. In this research, the impact of altiplano coloniz…
Mitochondrial DNA and Peopling of South America
The initial peopling of South America is largely unresolved, in part because of the unique distribution of genetic diversity in native South Americans. On average, genetic diversity estimated within Andean populations is higher than that estimated within Amazonian populations. Yet there is less genetic differentiation estimated among Andean populations than estimated among Amazonian populations. One hypothesis is that this pattern is a product of…
Ancient DNA from a pre‐Columbian Amerindian population
Ancient DNA was obtained from skeletal remains from the Norris Farms #36 cemetery, a pre‐Columbian archeological site in central Illinois that dates to A. D. 1300. Four mitochondrial DNA (mtDNA) markers were analyzed that delineate the four primary mtDNA lineages found in contemporary Amerindian populations. mtDNA types were determined for 50 individuals; 49 belonged to one of these four lineages. One lineage occurred only in males, suggesting an…
Twenty-first century bioarchaeology: Taking stock and moving forward
This article presents outcomes from a Workshop entitled "Bioarchaeology: Taking Stock and Moving Forward," which was held at Arizona State University (ASU) on March 6-8, 2020. Funded by the National Science Foundation (NSF), the School of Human Evolution and Social Change (ASU), and the Center for Bioarchaeological Research (CBR, ASU), the Workshop's overall goal was to explore reasons why research proposals submitted by bioarchaeologists, both g…
Ancient DNA and Genetic Continuity in the South Central Andes
Alternative models of residential mobility have been proposed to explain the development and spread of Tiwanaku influ ence across the south central Andes. Within the Osmore drainage, the rich Moquegua Valley has been hypothesized as the site of a significant colonization event (or events) whereby both the natural and human landscape was transformed and integrated into the expansive Tiwanaku state. In this research, the impact of altiplano coloniz…
Deficiencies and challenges in the study of ancient tuberculosis DNA
Tuberculosis and leprosy in perspective
Two of humankind's most socially and psychologically devastating diseases, tuberculosis and leprosy, have been the subject of intensive paleopathological research due to their antiquity, a presumed association with human settlement and subsistence patterns, and their propensity to leave characteristic lesions on skeletal and mummified remains. Despite a long history of medical research and the development of effective chemotherapy, these diseases…
Land, language, and loci: MtDNA in Native Americans and the genetic history of Peru
Despite a long history of complex societies and despite extensive present-day linguistic and ethnic diversity, relatively few populations in Peru have been sampled for population genetic investigations. In order to address questions about the relationships between South American populations and about the extent of correlation between genetic distance, language, and geography in the region, mitochondrial DNA (mtDNA) hypervariable region I sequence…
Tuberculosis on the north coast of Peru: Skeletal and molecular paleopathology of late pre-Hispanic and postcontact mycobacterial disease
Population Genetic Structure of Traditional Populations in the Peruvian Central Andes and Implications for South American Population History
Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east contrast in patterns of population genetic variation is typically attributed to large-scale phe…
Advancing the understanding of treponemal disease in the past and present
Syphilis was perceived to be a new disease in Europe in the late 15th century, igniting a debate about its origin that continues today in anthropological, historical, and medical circles. We move beyond this age‐old debate using an interdisciplinary approach that tackles broader questions to advance the understanding of treponemal infection (syphilis, yaws, bejel, and pinta). How did the causative organism(s) and humans co‐evolve? How did the rel…
Ancient pathogen genomics: Insights Into Timing and Adaptation
Brief communication: Molecular analysis of the Kwäday Dän Ts'finchi ancient remains found in a glacier in Canada
DNA was extracted from the frozen remains of a man found in the northwest corner of British Columbia, Canada, in 1999. His clothing was radiocarbon‐dated at ca. 550 years old. Nitrogen and carbon content in whole bone and collagen‐type residue extracted from both bone and muscle indicated good preservation of proteinaceous macromolecules. Restriction enzyme analysis of mitochondrial DNA (mtDNA) determined that the remains belong to haplogroup A, …
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
Hybridization effects and genetic diversity of the common and black‐tufted marmoset ( C allithrix jacchus and C allithrix penicillata ) mitochondrial control region
Hybridization is continually documented in primates, but effects of natural and anthropogenic hybridization on biodiversity are still unclear and differentiating between these contexts remains challenging in regards to primate evolution and conservation. Here, we examine hybridization effects on the mitochondrial DNA (mtDNA) control region of Callithrix marmosets, which provide a unique glimpse into interspecific mating under distinct anthropogen…
An anthropological genetic perspective on creolization in the anglophone caribbean
Variable socio‐cultural influences developed in the colonial Caribbean as a result of competing European hegemonic rule. In this study, we examine how colonial regulations regarding social hierarchies and mate choice worked to influence the genetic landscape of contemporary African Caribbean populations. To this end, 420 individuals from Dominica, Grenada, St. Kitts, St. Lucia, St. Thomas, St. Vincent, Jamaica, and Trinidad were genotyped for 105…
Phylogeny of the jacchus group of Callithrix marmosets based on complete mitochondrial genomes
OBJECTIVES: Two subgroups make up the marmoset genus Callithrix. The "aurita" group is composed of two species, whereas evolutionary relationships among the four species of the "jacchus" group remain unclear. To uncover these relationships, we first sequenced mitochondrial genomes for C. kuhlii and C. penicillata to complement data available for congeners. We then constructed a phylogenetic tree based on mtDNA heavy chain protein coding genes fro…
Facing the facts: The Runx2 gene is associated with variation in facial morphology in primates
Understanding Turkey Management in the Mimbres Valley of Southwestern New Mexico Using Ancient Mitochondrial DNA and Stable Isotopes
In the US Southwest and Northwest Mexico, people and turkeys (Meleagris gallopavo) have had a reciprocal relationship for millennia; turkeys supplied feathers, meat, and other resources, whereas people provided food, shelter, and care. To investigate how turkeys fit within subsistence, economic production, sociopolitical organization, and religious and ritual practice in the Mimbres Valley of southwestern New Mexico, we report on genetic (mtDNA) …
The efficacy of whole human genome capture on ancient dental calculus and dentin
OBJECTIVES: Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques. MATERIALS AND METHODS: Total DNA extracted from 24 pai…
Determining the population affinity of an unprovenienced human skull for repatriation
An archaeological assessment was carried out on an unprovenienced human skull recovered in eastern Idaho, exhibiting cranial deformation and peri-mortem application of a red pigment. A combination of scanning electron microscopy (SEM), X-ray fluorescence (XRF), and energy-dispersive X-ray spectroscopy (EDS) identified the major and trace elements present in the red pigment as natural cinnabar. Carbon and oxygen stable isotopes from teeth and bone…
On the Diffusion-Wave Model for the Spread of Modern Humans
Comparison of two ancient DNA extraction protocols for skeletal remains from tropical environments
OBJECTIVES: The tropics harbor a large part of the world's biodiversity and have a long history of human habitation. However, paleogenomics research in these climates has been constrained so far by poor ancient DNA yields. Here we compare the performance of two DNA extraction methods on ancient samples of teeth and petrous portions excavated from tropical and semi-tropical sites in Tanzania, Mexico, and Puerto Rico (N = 12). MATERIALS AND METHODS…
Ancient DNA from a pre‐Columbian Amerindian population
Ancient DNA was obtained from skeletal remains from the Norris Farms #36 cemetery, a pre‐Columbian archeological site in central Illinois that dates to A. D. 1300. Four mitochondrial DNA (mtDNA) markers were analyzed that delineate the four primary mtDNA lineages found in contemporary Amerindian populations. mtDNA types were determined for 50 individuals; 49 belonged to one of these four lineages. One lineage occurred only in males, suggesting an…
Sex determination of ancient human skeletons using DNA
A method for determining the sex of human skeletons was developed using molecular genetic techniques. The amelogenin gene, found on the X and Y chromosomes, was examined using the polymerase chain reaction (PCR) and a nonradioactive dot blot procedure. DNA was analyzed from 20 modern individuals of known sex and 20 skeletons from an archaeological site in central Illinois dating to A.D. 1300. An independent assessment of the sex of each skeleton …
Sex determination of ancient human skeletons using DNA
A method for determining the sex of human skeletons was developed using molecular genetic techniques. The amelogenin gene, found on the X and Y chromosomes, was examined using the polymerase chain reaction (PCR) and a nonradioactive dot blot procedure. DNA was analyzed from 20 modern individuals of known sex and 20 skeletons from an archaeological site in central Illinois dating to A.D. 1300. An independent assessment of the sex of each skeleton …
Neandertal DNA Sequences and the Origin of Modern Humans
MtDNA Analysis of a Prehistoric Oneota Population: Implications for the Peopling of the New World
Matteo da Perugia
Brief communication: Molecular analysis of the Kwäday Dän Ts'finchi ancient remains found in a glacier in Canada
DNA was extracted from the frozen remains of a man found in the northwest corner of British Columbia, Canada, in 1999. His clothing was radiocarbon‐dated at ca. 550 years old. Nitrogen and carbon content in whole bone and collagen‐type residue extracted from both bone and muscle indicated good preservation of proteinaceous macromolecules. Restriction enzyme analysis of mitochondrial DNA (mtDNA) determined that the remains belong to haplogroup A, …
On the Diffusion-Wave Model for the Spread of Modern Humans
Land, language, and loci: MtDNA in Native Americans and the genetic history of Peru
Despite a long history of complex societies and despite extensive present-day linguistic and ethnic diversity, relatively few populations in Peru have been sampled for population genetic investigations. In order to address questions about the relationships between South American populations and about the extent of correlation between genetic distance, language, and geography in the region, mitochondrial DNA (mtDNA) hypervariable region I sequence…
Diet and the evolution of human amylase gene copy number variation
Mitochondrial DNA and Peopling of South America
The initial peopling of South America is largely unresolved, in part because of the unique distribution of genetic diversity in native South Americans. On average, genetic diversity estimated within Andean populations is higher than that estimated within Amazonian populations. Yet there is less genetic differentiation estimated among Andean populations than estimated among Amazonian populations. One hypothesis is that this pattern is a product of…
Ancient DNA and Genetic Continuity in the South Central Andes
Alternative models of residential mobility have been proposed to explain the development and spread of Tiwanaku influ ence across the south central Andes. Within the Osmore drainage, the rich Moquegua Valley has been hypothesized as the site of a significant colonization event (or events) whereby both the natural and human landscape was transformed and integrated into the expansive Tiwanaku state. In this research, the impact of altiplano coloniz…
Deficiencies and challenges in the study of ancient tuberculosis DNA
Tuberculosis and leprosy in perspective
Two of humankind's most socially and psychologically devastating diseases, tuberculosis and leprosy, have been the subject of intensive paleopathological research due to their antiquity, a presumed association with human settlement and subsistence patterns, and their propensity to leave characteristic lesions on skeletal and mummified remains. Despite a long history of medical research and the development of effective chemotherapy, these diseases…
Tuberculosis on the north coast of Peru: Skeletal and molecular paleopathology of late pre-Hispanic and postcontact mycobacterial disease
AAPA Presentation Schedule
The history of infectious disease in humans (and to a lesser extent other primates) has been studied from different perspectives including those of bioarchaeology, medical history, and evolutionary genetics. Technical advances in nucleotide sequencing as well as in the ability to obtain genetic material from difficult sources (such as feces and ancient materials) have enhanced our ability to examine both ancient pathogens and pathogens that are d…
An anthropological genetic perspective on creolization in the anglophone caribbean
Variable socio‐cultural influences developed in the colonial Caribbean as a result of competing European hegemonic rule. In this study, we examine how colonial regulations regarding social hierarchies and mate choice worked to influence the genetic landscape of contemporary African Caribbean populations. To this end, 420 individuals from Dominica, Grenada, St. Kitts, St. Lucia, St. Thomas, St. Vincent, Jamaica, and Trinidad were genotyped for 105…
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Population Genetic Structure of Traditional Populations in the Peruvian Central Andes and Implications for South American Population History
Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east contrast in patterns of population genetic variation is typically attributed to large-scale phe…
Hybridization effects and genetic diversity of the common and black‐tufted marmoset ( C allithrix jacchus and C allithrix penicillata ) mitochondrial control region
Hybridization is continually documented in primates, but effects of natural and anthropogenic hybridization on biodiversity are still unclear and differentiating between these contexts remains challenging in regards to primate evolution and conservation. Here, we examine hybridization effects on the mitochondrial DNA (mtDNA) control region of Callithrix marmosets, which provide a unique glimpse into interspecific mating under distinct anthropogen…
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
Ancient pathogen genomics: Insights Into Timing and Adaptation
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive an…
Application of PE‐Radseq to the study of genomic diversity and divergence of two Brazilian marmoset species ( Callithrix jacchus and C. penicillata )
Callithrix jacchus and C. penicillata are among the smallest anthropoid primates, are highly specialized tree gougers, and largely occupy Brazil's most extreme, semi-arid biomes. However, the underlying genomic factors that underpin the evolution of these species and their unique traits are under-investigated. Additionally, exotic populations of these two species are widely established throughout Brazil and hybridize with threatened native conger…
Determining the population affinity of an unprovenienced human skull for repatriation
An archaeological assessment was carried out on an unprovenienced human skull recovered in eastern Idaho, exhibiting cranial deformation and peri-mortem application of a red pigment. A combination of scanning electron microscopy (SEM), X-ray fluorescence (XRF), and energy-dispersive X-ray spectroscopy (EDS) identified the major and trace elements present in the red pigment as natural cinnabar. Carbon and oxygen stable isotopes from teeth and bone…
Biology (27 works) · Evolutionary biology (21 works) · Genetics (19 works) · Geography (17 works) · Gene (16 works) · Population (16 works) · Forensic and Genetic Research (15 works) · Genetics (15 works) · Ancient DNA (14 works) · Archaeology (14 works)