Jeffrey D Klausner
Dados Biográficos
| ID | 104923 |
|---|---|
| NOME | Jeffrey D Klausner |
| PRENOMES | Jeffrey D |
| SOBRENOME | Klausner |
| ASSINATURA | KLAUSNER J D |
| AFILIAÇÕES | San Francisco Department of Public Health |
| ORCID | 0000-0002-6922-7364 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 69 |
| TOTAL DE CITAÇÕES | 76 |
| TOTAL COMO AUTOR | 69 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1999 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 6 |
Educational Attainment and HIV Prevalence by Age Among Pregnant Women in South Africa
We examined the association between educational attainment and HIV positivity among pregnant women in a high HIV-prevalence setting and assessed how this relationship varies by age to inform targeted prevention strategies. This cross-sectional study included 2003 pregnant women aged 21-44 years attending their first antenatal visit (<27 weeks' gestation) at four public health facilities in East London, South Africa, between March 2021 and May 202…
A Renewed Effort to Control and Eliminate Congenital Syphilis in the United States
Empowering Women’s PrEP Choices
Pregnant and breastfeeding women (PBW) are at heightened risk of HIV acquisition. We aimed to explore PBW's preferences of various long-acting PrEP modalities. In-depth interviews were conducted with PBW at three sites: Cape Town, East London (South Africa), and Gaborone (Botswana). We conducted thematic analysis, guided by the Health Belief Model, to examine participants' HIV risk perception during pregnancy and breastfeeding, their perceived in…
Preference for Service Delivery for Long-Acting Pre-exposure Prophylaxis for HIV Infection Among Pregnant and Breastfeeding Women in South Africa and Botswana
HIV particularly affects women during pregnancy and postpartum, where they face a two-fold or more increased risk of HIV acquisition. We explored preferences for long-acting PrEP and multipurpose prevention technologies among pregnant and breastfeeding women (PBFW) without HIV. From April to December 2023, we conducted a discrete choice experiment at maternal healthcare clinics in Cape Town, East London (South Africa), and Gaborone (Botswana) inc…
PrEP Disparities Among Transgender Feminine, Transgender Masculine, Nonbinary, and Gender Expansive Youth and Young Adults in the United States
This study assessed disparities in pre-exposure prophylaxis (PrEP) use among transgender and gender expansive youth and young adults (N = 477) between 15 and 24 years old in the CARES (ATN 149) and TechStep (ATN 160) study protocols within the National Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). Structural equation modeling was used to test mediation pathways between gender identity and PrEP uptake among the full sample a…
Online Peer Support for Youth at Higher Risk of or Living with HIV
With the rise of technology-based interventions for HIV risk reduction among adolescents, research is needed to assess how youth participate in these strategies. We used qualitative content analysis to examine youth's posts in an online peer support intervention through the Adolescent Trials Network (ClinicalTrials.gov NCT03134833, registered May 1, 2017) for youth at higher risk of or living with HIV. We analyzed 308 posts across 85 conversation…
Developing an mHealth program to improve HIV care continuum outcomes among young Black gay and bisexual men
This study demonstrates the potential of a video-based mHealth program to address the unique needs of YBGBM living with HIV, offering support and comprehensive information through a user-friendly interface and videos of peers living with HIV and of experts. The HCD approach allowed for continuous improvements to the concept to maximize cultural appropriateness, utility, and potential effectiveness for both YBGBM and HIV service organizations
Strategies to Facilitate Service Utilization Among Youth at Risk for HIV
Sexual and gender minority youth (SGMY) are vulnerable to acquiring HIV and need HIV prevention and health services, but may have competing needs. A prior analysis found that PrEP use reports increased in a combination intervention study arm with coaching, peer support, and automated text-messages. This paper examines ancillary support and healthcare services utilization as secondary intervention objectives. SGMY (N = 895, 40% Black, 29% Latino) …
Trust in science and scientists among university students, staff, and faculty of a large, diverse university in Los Angeles during the Covid-19 pandemic, the Trojan Pandemic Response Initiative
Despite the setting of a major research University, trust in science is highly variable. This study identifies characteristics that could be used to target and curate educational campaigns and university policies to address the COVID19 and future pandemics
Characteristics associated with attitudes and behaviors towards mask wearing during the Covid-19 pandemic
Race and ethnicity, political affiliation, and division may affect attitudes and behaviors in mask wearing. Further investigation into how characteristics influence public health measures such as mask wearing is needed to contain the spread of the COVID-19 virus, other infectious diseases, and future pandemics
Gay, Bisexual, and Other Men Who Have Sex With Men Who Are Not on Oral PrEP may be Less Interested in Available Injectable Products than in Oral PrEP
Substance Use, Violence, and Sexual Risk Among Young Cis-Gender Women Placed at High-Risk for Human Immunodeficiency Virus Infection
Chlamydia trachomatis Screening and Treatment in Pregnancy to Reduce Adverse Pregnancy and Neonatal Outcomes
Chlamydial trachomatis infection has been associated with adverse pregnancy and neonatal outcomes such as premature rupture of membranes, preterm birth, low birth weight, conjunctivitis, and pneumonia in infants. This review evaluates existing literature to determine potential benefits of antenatal screening and treatment of C. trachomatis in preventing adverse outcomes. A literature search revealed 1824 studies with 156 full-text articles review…
Heterogeneity in Sars-CoV-2 Positivity by Ethnicity in Los Angeles
Evaluating the impact of stay-at-home orders on the time to reach the peak burden of Covid-19 cases and deaths
Our study supports the association between the timing of stay-at-home orders and the time to peak case and death counts for both countries and US states. Regions in which mandates were implemented late experienced a prolonged duration to reaching both peak daily case and death counts
The role of trust and health literacy in nurse-delivered point-of-care STI testing for pregnant women living with HIV, Tshwane District, South Africa
We recommend implementing patient health literacy programmes as part of POC services to support women in remembering and disclosing their specific STI diagnosis to sexual partners, which may facilitate partner treatment uptake and thus decrease the risk of re-infection
Geographic Access to Preexposure Prophylaxis and the Case for Telemedicine
AffiliationsKeith Yiu Kei Wong is with the David Geffen School of Medicine at University of California, Los Angeles. Jeffrey D. Klausner is with the Division of Infectious Diseases, Department of Medicine, University of California, Los Angeles
Using partner notification to address curable sexually transmitted infections in a high HIV prevalence context
The integration of STI, HIV, and antenatal care services may have contributed to most women's willingness to notify partners. However, logistical barriers to partner treatment remained. More research is needed to identify effective and appropriate strategies for scaling-up partner notification services in order to improve rates of partners successfully contacted and treated, reduce rates of STI reinfection during pregnancy, and ultimately reduce …
Venue-Based HIV-Testing
The Relationship Between Risk Perception and Frequency of HIV Testing Among Men Who Have Sex with Men and Transgender Women, Lima, Peru
Do Subjective Alcohol Screening Tools Correlate with Biomarkers Among High-Risk Transgender Women and Men Who Have Sex with Men in Lima, Peru
Regular clinic attendance in two large San Francisco HIV primary care settings
Although poor clinic attendance is associated with increased morbidity and mortality among HIV-infected individuals, less is known about predictors of retention and the acceptability of targeted interventions to increase regular clinic attendance. To better understand which patients are at risk for irregular clinic attendance and to explore interventions to aid in retention to care, we surveyed patients attending two outpatient HIV clinics affili…
HIV Status Communication with Sex Partners and Associated Factors Among High-Risk MSM and Transgender Women in Lima, Peru
Critical Evaluation of Adler’s Challenge to the cdc’s Male Circumcision Recommendations
We evaluate Peter Adler’s challenge to the Centers for Disease Control and Prevention ( cdc ) draft recommendations on male circumcision (this issue, see pp. 237–262 ). The cdc advocates elective male circumcision ( mc ) to improve public health in the usa based on strong scientific evidence. In marked contrast to the cdc , Adler’s criticisms depend on speculative claims and obfuscation of the scientific data. Adler’s central argument that circum…
Male circumcision for protection against HIV infection in sub-Saharan Africa
This article responds to a recent 'controversy study' in Global Public Health by de Camargo et al. directed at three randomised controlled trials (RCTs) of male circumcision (MC) for HIV prevention. These trials were conducted in three countries in sub-Saharan Africa (SSA) and published in 2005 and 2007. The RCTs confirmed observational data that had accumulated over the preceding two decades showing that MC reduces by 60% the risk of HIV infecti…
Impact of Highly Active Antiretroviral Treatment on HIV Seroincidence Among Men Who Have Sex With Men
Objectives. This study assessed the countervailing effects on HIV incidence of highly active antiretroviral treatment (HAART) among San Francisco men who have sex with men (MSM). Methods. Behavioral risk was determined on the basis of responses to cross-sectional community interviews. HIV incidence was assessed through application of an enzyme-linked immunoassay testing strategy. Results. Use of HAART among MSM living with AIDS increased from 4% …
Self-Reported Sexual Identity, Sexual Behaviors and Health Risks
Data from a population-based survey of low-income young women (n = 2,438) was used to examine substance use patterns and exposure to coerced sexual activity among women who self-identify as lesbian (n = 34) or bisexual (n = 91), or who report sexual behavior exclusively with other women (n = 17) or with both women and men (n = 189). Findings for women classified by self-identity and by sexual behavior are compared. Women who identified as bisexua…
Sexinfo
In response to rising gonorrhea rates among African American youth in San Francisco, Calif, Internet Sexuality Information Services, Inc, in partnership with the San Francisco Department of Public Health, developed SEXINFO, a sexual health text messaging service. SEXINFO is an information and referral service that can be accessed by texting “SEXINFO” to a 5-digit number from any wireless phone. A consortium of community organizations, religious g…
Continuing Increases in Sexual Risk Behavior and Sexually Transmitted Diseases Among Men Who Have Sex With Men
We recently reported on worrisome increases in sexual risk behavior, sexually transmitted diseases (STDs), and HIV incidence among men who have sex with men (MSM) during a period of increasing use of highly active antiretroviral therapy (HAART), from 1994 to 1999.1 We have since obtained data on sexual risk behavior for 2000 and 2001. In addition, we have added to our surveys questions on whether unsafe sex was occurring with partners of unknown …
Elimination and reintroduction of primary and secondary syphilis
OBJECTIVES: This study was conducted to define factors associated with the epidemic spread, elimination, and reintroduction of primary and secondary syphilis in King County, Washington, from 1987 through 1998. METHODS: Reports of primary and secondary syphilis in King County from 1987 through 1998 were reviewed retrospectively. RESULTS: During the epidemic spread of syphilis, only 15.8% of cases were imported. A total of 24.0% of patients reporte…
Sexual and Drug Use Behavior Among Women Who Have Sex With Both Women and Men
Recent HIV/AIDS trends in the United States suggest a relative increase in HIV infections among women attributed to injection drug use or heterosexual contact.1 Although the biological risk of female-to-female sexually transmitted HIV is unknown, it is thought to be much lower than the risk of transmission between men and women, including instances in which a condom is used.2 However, studies focusing on women who have sex with women (WSW) have s…
Street Medicine”
Chlamydia and gonorrhea rates among African American youths in San Francisco are far higher than those among young people of the city’s other racial and ethnic groups. A geographically targeted sexually transmitted disease education and screening intervention performed in collaboration with a local faith-based organization was able to screen hundreds of at-risk youths. The screened individuals included friends and sex partners from an extensive s…
Hepatitis C Virus Infection in Young, Low-Income Women
Objectives. We evaluated risk for hepatitis C virus (HCV) infection in women residing in low-income neighborhoods of northern California. Methods. A population-based sample of 1707 women, aged 18 to 29, were surveyed and screened for sexually transmitted infections and HCV. Results. Women infected with HCV (2.5%) were more likely to have a history of injection and noninjection drug use, to exchange sex for money or drugs, and to have sexually tra…
Simplifying Consent Increases Hiv Testing and New Case Detection
We read with interest the impact of New York State's streamlined HIV testing consent procedures on HIV testing rates, and we were pleased to see that the results were consistent with our experience in San Francisco.1 However, we would like to correct an inaccuracy. Wing argued that the lack of a control group in our analysis decreased the strength of our conclusions. We had published a one-year follow up of our initial report in which we included…
Same-Sex Domestic Partnerships and Lower-Risk Behaviors for STDs, Including HIV Infection
To determine the association between domestic partnership status and risk behaviors for sexually transmitted diseases, including HIV infection, we analyzed data from a population-based interviewer-administered telephone survey of 2,881 gay men in San Francisco, Los Angeles, New York and Chicago conducted in November 1996 to February 1998. Men in domestic partnerships had a statistically significantly lower prevalence of multiple partnerships, "on…
Written Informed Consent and Hiv Testing Rates
Goldman et al. posit without empirical evidence that written informed consent is not a barrier to routine HIV testing.1 Our experience in San Francisco, California, suggests otherwise. In May 2006, the San Francisco Department of Public Health Medical Care System, which includes an acute care hospital, a long-term care facility, and more than 15 primary health care centers, eliminated the requirement for a separate written informed consent form f…
Field-Delivered Therapy Increases Treatment for Chlamydia and Gonorrhea
In 1998, treatment completion was low among chlamydia and gonorrhea cases reported to the San Francisco Department of Public Health and assigned for treatment follow-up. To improve treatment completion among growing numbers of chlamydia and gonorrhea cases, the department implemented field-delivered therapy (FDT), a single-dose, directly observed therapy protocol for uncomplicated chlamydial and gonococcal infections. After the protocol was imple…
Elimination and reintroduction of primary and secondary syphilis
OBJECTIVES: This study was conducted to define factors associated with the epidemic spread, elimination, and reintroduction of primary and secondary syphilis in King County, Washington, from 1987 through 1998. METHODS: Reports of primary and secondary syphilis in King County from 1987 through 1998 were reviewed retrospectively. RESULTS: During the epidemic spread of syphilis, only 15.8% of cases were imported. A total of 24.0% of patients reporte…
Tracing a Syphilis Outbreak Through Cyberspace
CONTEXT: A recent outbreak of syphilis among users of an Internet chat room challenged traditional methods of partner notification and community education because locating information on sexual partners was limited to screen names and privacy concerns precluded identifying sexual partners through the Internet service provider. OBJECTIVES: To determine the association of Internet use and acquisition of syphilis and to describe innovative methods o…
Cruising on the Internet Highway
This study evaluated differences in sexual behavior and risk for sexually transmitted diseases (STDs) among men who have sex with men (MSM) who met their partners on-line and those who did not. A self-administered questionnaire on sexual behavior was offered to a convenience sample of patients seeking public STD services. Thirty-two percent of MSM patients reported meeting a sexual partner over the Internet in the past year. MSM with on-line part…
Vulnerability to HIV Among Women Formerly Incarcerated and Women with Incarcerated Sexual Partners
Impact of a Single Session of Counseling on Partner Referral for Sexually Transmitted Disease Treatment, Harare, Zimbabwe
Self-Reported Sexual Identity, Sexual Behaviors and Health Risks
Data from a population-based survey of low-income young women (n = 2,438) was used to examine substance use patterns and exposure to coerced sexual activity among women who self-identify as lesbian (n = 34) or bisexual (n = 91), or who report sexual behavior exclusively with other women (n = 17) or with both women and men (n = 189). Findings for women classified by self-identity and by sexual behavior are compared. Women who identified as bisexua…
Hepatitis C Virus Infection in Young, Low-Income Women
Objectives. We evaluated risk for hepatitis C virus (HCV) infection in women residing in low-income neighborhoods of northern California. Methods. A population-based sample of 1707 women, aged 18 to 29, were surveyed and screened for sexually transmitted infections and HCV. Results. Women infected with HCV (2.5%) were more likely to have a history of injection and noninjection drug use, to exchange sex for money or drugs, and to have sexually tra…
Continuing Increases in Sexual Risk Behavior and Sexually Transmitted Diseases Among Men Who Have Sex With Men
We recently reported on worrisome increases in sexual risk behavior, sexually transmitted diseases (STDs), and HIV incidence among men who have sex with men (MSM) during a period of increasing use of highly active antiretroviral therapy (HAART), from 1994 to 1999.1 We have since obtained data on sexual risk behavior for 2000 and 2001. In addition, we have added to our surveys questions on whether unsafe sex was occurring with partners of unknown …
Impact of Highly Active Antiretroviral Treatment on HIV Seroincidence Among Men Who Have Sex With Men
Objectives. This study assessed the countervailing effects on HIV incidence of highly active antiretroviral treatment (HAART) among San Francisco men who have sex with men (MSM). Methods. Behavioral risk was determined on the basis of responses to cross-sectional community interviews. HIV incidence was assessed through application of an enzyme-linked immunoassay testing strategy. Results. Use of HAART among MSM living with AIDS increased from 4% …
Sexual and Drug Use Behavior Among Women Who Have Sex With Both Women and Men
Recent HIV/AIDS trends in the United States suggest a relative increase in HIV infections among women attributed to injection drug use or heterosexual contact.1 Although the biological risk of female-to-female sexually transmitted HIV is unknown, it is thought to be much lower than the risk of transmission between men and women, including instances in which a condom is used.2 However, studies focusing on women who have sex with women (WSW) have s…
Field-Delivered Therapy Increases Treatment for Chlamydia and Gonorrhea
In 1998, treatment completion was low among chlamydia and gonorrhea cases reported to the San Francisco Department of Public Health and assigned for treatment follow-up. To improve treatment completion among growing numbers of chlamydia and gonorrhea cases, the department implemented field-delivered therapy (FDT), a single-dose, directly observed therapy protocol for uncomplicated chlamydial and gonococcal infections. After the protocol was imple…
Internet-based site-specific interventions for syphilis prevention among gay and bisexual men
Recent increases in syphilis in gay men in urban areas in the US and Europe have been associated with men meeting new sex partners on the Internet in chat-rooms and at websites that facilitate partner meeting. In response to the syphilis epidemic in San Francisco, the San Francisco Department of Public Health partnered with a community-based organization, Internet Sexuality Information Services, Inc., to develop, implement and evaluate a broad ra…
Street Medicine”
Chlamydia and gonorrhea rates among African American youths in San Francisco are far higher than those among young people of the city’s other racial and ethnic groups. A geographically targeted sexually transmitted disease education and screening intervention performed in collaboration with a local faith-based organization was able to screen hundreds of at-risk youths. The screened individuals included friends and sex partners from an extensive s…
From Research to Policy
In September 2000, the governor of California signed into law Senate Bill 648 which authorized physicians in California to dispense enough extra medication to patients infected with Chlamydia to treat their sex partners.1 The Centers for Disease Prevention and Control recently recommended that this practice of expedited partner therapy be a key component of the medical management of urogenital chlamydial infections.2
Lesson Learned From Tobacco Control
Lessons learned from tobacco control
A public health response to the methamphetamine epidemic
Clinical responses to CM in PROP were similar to CM delivered in drug treatment programs, supporting the adaptability and effectiveness of CM to non-traditional drug treatment settings. Costs were reasonable and less than or comparable to other methamphetamine outpatient treatment programs. Further expansion of programs like PROP could address the increasing need for acceptable, feasible and cost-effective methamphetamine treatment in this group …
The Acceptability and Feasibility of the Positive Reinforcement Opportunity Project, a Community-Based Contingency Management Methamphetamine Treatment Program for Gay and Bisexual Men in San Francisc…
The Positive Reinforcement Opportunity Project (PROP) was a pilot program developed to build on the efficacy of contingency management (CM) using positive reinforcement to address the treatment needs of gay and bisexual men currently using crystal methamphetamines (meth). It was hypothesized that a version of CM could be implemented in San Francisco that was less costly than traditional treatment methods and reached gay and other MSM using meth w…
Same-Sex Domestic Partnerships and Lower-Risk Behaviors for STDs, Including HIV Infection
To determine the association between domestic partnership status and risk behaviors for sexually transmitted diseases, including HIV infection, we analyzed data from a population-based interviewer-administered telephone survey of 2,881 gay men in San Francisco, Los Angeles, New York and Chicago conducted in November 1996 to February 1998. Men in domestic partnerships had a statistically significantly lower prevalence of multiple partnerships, "on…
Novel recruitment strategies to increase participation of women in reproductive health research in India
In India, care seeking for reproductive health among women is inadequate. This poses a unique challenge to researchers recruiting cohorts for studies in clinic-based settings. The purpose of this paper is to describe the recruitment process used in a prospective cohort study investigating the relationship between bacterial vaginosis and acquisition of HSV-2 among sexually active women in Mysore, India. Participants were initially recruited from a…
High Rates of Sex with Men among High-Risk, Heterosexually-Identified Men in Low-Income, Coastal Peru
New Populations at High Risk of HIV/STIs in Low-income, Urban Coastal Peru
Reassessing HIV Prevention
The largest investments in AIDS prevention targeted to the general population are being made in interventions where the evidence for large-scale impact is uncertain.
Prevalence of HIV, Herpes Simplex Virus-2, and Syphilis in male sex partners of pregnant women in Peru
Pregnant women's sex partners reported lifetime sexual contact with core risk groups, had an elevated prevalence of HSV-2, and demonstrated the potential to spread HIV and other STIs to their partners. Though the prevalence of HIV in the population was not significantly higher than observed in other samples of heterosexuals in Peru, the risk of HIV transmission to their female partners may be exacerbated by their increased prevalence of HSV-2 inf…
Use of Sentinel Surveillance and Geographic Information Systems to Monitor Trends in HIV Prevalence, Incidence, and Related Risk Behavior among Women Undergoing Syphilis Screening in a Jail Setting
Medicine (66 obras) · HIV/AIDS Research and Interventions (45 obras) · Family medicine (44 obras) · Public health (42 obras) · Environmental health (35 obras) · Demography (30 obras) · Adolescent Sexual and Reproductive Health (28 obras) · HIV, Drug Use, Sexual Risk (28 obras) · Population (28 obras) · Syphilis (28 obras)