Angela N H Creager
Dados Biográficos
| ID | 123283 |
|---|---|
| NOME | Angela N H Creager |
| PRENOMES | Angela N H |
| SOBRENOME | Creager |
| ASSINATURA | CREAGER A N H |
| AFILIAÇÕES | Princeton University |
| ORCID | 0000-0002-7763-6432 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 26 |
| TOTAL DE CITAÇÕES | 65 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 3 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1995 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 4 |
Can a simple test in bacteria identify cancer-causing chemicals in humans
Since the 1950s, US officials have sought to reduce cancer incidence by regulating chemical exposures. However, rodent carcinogenicity tests are lengthy and expensive, making it impractical to identify carcinogens among the tens of thousands of chemicals on the market through animal testing. Introduced in 1973, the quick and inexpensive ‘Ames test’ indicated whether a chemical caused mutations in bacteria, and putatively cancer in humans. In the …
The Story of a Statue
Narratives of Genetic Selfhood
This essay considers the mid‐twentieth century adoption of genetic explanations for three biological phenomena: nutritional adaptation, antibiotic resistance, and antibody production. This occurred at the same time as the hardening of the neo‐Darwinian Synthesis in evolutionary theory. I argue that these concurrent changes reflect an ascendant narrative of genetic selfhood, which prioritized random hereditary variation and selection through compe…
Risk on the Table
Risk on the Table
Over the last century, the industrialization of agriculture and processing technologies have made food abundant and relatively inexpensive for much of the world’s population. Simultaneously, pesticides, nitrates, and other technological innovations intended to improve the food supply’s productivity and safety have generated new, often poorly understood risks for consumers and the environment. From the proliferation of synthetic additives to the t…
The molecular vista
This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revit…
Residues
To Test or Not to Test
When the Toxic Substances Control Act (TSCA) was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of indu…
Recipes for recombining DNA
Laboratory instructions and recipes are sometimes edited into books with a wide circulation. Even in the late twentieth century, publications of this nature remained influential. For example, protocols from a 1980 summer course on gene cloning at Cold Spring Harbor Laboratory provided the basis for a bestselling laboratory manual by Tom Maniatis, Ed Fritsch and Joe Sambrook. Not only did the Molecular Cloning: A Laboratory Manual become a standar…
Learning by the book
This essay offers an overview of how manuals and handbooks have contributed to the standardization, codification, transmission and revision of knowledge. These instructional and reference texts are distinct from related educational genres such as textbooks and editions due to their focus on practical knowledge. They are also notable for their appearance in diverse times and places, such as ancient Greece, early and medieval China and early modern…
Residues
This essay offers a new approach for conceptualizing the environmental impact of chemicals production, consumption, disposal, and regulation. Environmental protection regimes tend to be highly segmented according to place, media, substance, and effect. Existing scholarship often reflects this same segmentation, by focusing on a locality, specific chemical, social movement, or regulatory body. In turn, as new environmental measures are introduced …
Human bodies as chemical sensors
Rendering Life Molecular
Reviewed by: Rendering Life Molecular: Models, Modelers, and Excitable Matter by Natasha Myers Angela N. H. Creager (bio) Rendering Life Molecular: Models, Modelers, and Excitable Matter. By Natasha Myers. Durham, NC: Duke University Press, 2015. Pp. 328. $26.95. Science studies scholars have grown accustomed to hearing contemporary biology described in terms of genomics, DNA sequences, and computation. Natasha Myers's Rendering Life Molecular ho…
Happily ever after” for cancer viruses
Phosphorus-32 in the Phage Group
Radioisotopes as political instruments, 1946-1953
The development of nuclear "piles," soon called reactors, in the Manhattan Project provided a new technology for manufacturing radioactive isotopes. Radioisotopes, unstable variants of chemical elements that give off detectable radiation upon decay, were available in small amounts for use in research and therapy before World War II. In 1946, the U.S. government began utilizing one of its first reactors, dubbed X-10 at Oak Ridge, as a production f…
After the Double Helix
Rosalind Franklin is best known for her informative X-ray diffraction patterns of DNA that provided vital clues for James Watson and Francis Crick's double-stranded helical model. Her scientific career did not end when she left the DNA work at King's College, however. In 1953 Franklin moved to J. D. Bernal's crystallography laboratory at Birkbeck College, where she shifted her focus to the three-dimensional structure of viruses, obtaining diffrac…
Adaptation or selection? Old issues and new stakes in the postwar debates over bacterial drug resistance
Lawrence, Rockefeller Money, the Laboratory and Medicine in Edinburgh 1919–1930
Science without Laws
Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects-such as flies, mice, worms, or microbes-or, as they are known in biology, …
Feminism in Twentieth-Century Science, Technology, and Medicine
What useful changes has feminism brought to science? Feminists have enjoyed success in their efforts to open many fields to women as participants. But the effects of feminism have not been restricted to altering employment and professional opportunities for women. The essays in this volume explore how feminist theory has had a direct impact on research in the biological and social sciences, in medicine, and in technology, often providing the impe…
The life of a virus
Tracing the politics of changing postwar research practices
Correcting the Blueprint of Life
Bulletin of the History of Medicine - Volume 73, Number 3, Fall 1999
What Blood Told Dr Cohn
Science without Laws
Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects-such as flies, mice, worms, or microbes-or, as they are known in biology, …
Learning by the book
This essay offers an overview of how manuals and handbooks have contributed to the standardization, codification, transmission and revision of knowledge. These instructional and reference texts are distinct from related educational genres such as textbooks and editions due to their focus on practical knowledge. They are also notable for their appearance in diverse times and places, such as ancient Greece, early and medieval China and early modern…
After the Double Helix
Rosalind Franklin is best known for her informative X-ray diffraction patterns of DNA that provided vital clues for James Watson and Francis Crick's double-stranded helical model. Her scientific career did not end when she left the DNA work at King's College, however. In 1953 Franklin moved to J. D. Bernal's crystallography laboratory at Birkbeck College, where she shifted her focus to the three-dimensional structure of viruses, obtaining diffrac…
What Blood Told Dr Cohn
To Test or Not to Test
When the Toxic Substances Control Act (TSCA) was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of indu…
Tracing the politics of changing postwar research practices
Narratives of Genetic Selfhood
This essay considers the mid‐twentieth century adoption of genetic explanations for three biological phenomena: nutritional adaptation, antibiotic resistance, and antibody production. This occurred at the same time as the hardening of the neo‐Darwinian Synthesis in evolutionary theory. I argue that these concurrent changes reflect an ascendant narrative of genetic selfhood, which prioritized random hereditary variation and selection through compe…
The molecular vista
This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revit…
Human bodies as chemical sensors
Phosphorus-32 in the Phage Group
Radioisotopes as political instruments, 1946-1953
The development of nuclear "piles," soon called reactors, in the Manhattan Project provided a new technology for manufacturing radioactive isotopes. Radioisotopes, unstable variants of chemical elements that give off detectable radiation upon decay, were available in small amounts for use in research and therapy before World War II. In 1946, the U.S. government began utilizing one of its first reactors, dubbed X-10 at Oak Ridge, as a production f…
The Uses of Life
Correcting the Blueprint of Life
Bulletin of the History of Medicine - Volume 73, Number 3, Fall 1999
What Blood Told Dr Cohn
The life of a virus
Tracing the politics of changing postwar research practices
Feminism in Twentieth-Century Science, Technology, and Medicine
What useful changes has feminism brought to science? Feminists have enjoyed success in their efforts to open many fields to women as participants. But the effects of feminism have not been restricted to altering employment and professional opportunities for women. The essays in this volume explore how feminist theory has had a direct impact on research in the biological and social sciences, in medicine, and in technology, often providing the impe…
Adaptation or selection? Old issues and new stakes in the postwar debates over bacterial drug resistance
Lawrence, Rockefeller Money, the Laboratory and Medicine in Edinburgh 1919–1930
Science without Laws
Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects-such as flies, mice, worms, or microbes-or, as they are known in biology, …
After the Double Helix
Rosalind Franklin is best known for her informative X-ray diffraction patterns of DNA that provided vital clues for James Watson and Francis Crick's double-stranded helical model. Her scientific career did not end when she left the DNA work at King's College, however. In 1953 Franklin moved to J. D. Bernal's crystallography laboratory at Birkbeck College, where she shifted her focus to the three-dimensional structure of viruses, obtaining diffrac…
Phosphorus-32 in the Phage Group
Radioisotopes as political instruments, 1946-1953
The development of nuclear "piles," soon called reactors, in the Manhattan Project provided a new technology for manufacturing radioactive isotopes. Radioisotopes, unstable variants of chemical elements that give off detectable radiation upon decay, were available in small amounts for use in research and therapy before World War II. In 1946, the U.S. government began utilizing one of its first reactors, dubbed X-10 at Oak Ridge, as a production f…
Happily ever after” for cancer viruses
Rendering Life Molecular
Reviewed by: Rendering Life Molecular: Models, Modelers, and Excitable Matter by Natasha Myers Angela N. H. Creager (bio) Rendering Life Molecular: Models, Modelers, and Excitable Matter. By Natasha Myers. Durham, NC: Duke University Press, 2015. Pp. 328. $26.95. Science studies scholars have grown accustomed to hearing contemporary biology described in terms of genomics, DNA sequences, and computation. Natasha Myers's Rendering Life Molecular ho…
Residues
This essay offers a new approach for conceptualizing the environmental impact of chemicals production, consumption, disposal, and regulation. Environmental protection regimes tend to be highly segmented according to place, media, substance, and effect. Existing scholarship often reflects this same segmentation, by focusing on a locality, specific chemical, social movement, or regulatory body. In turn, as new environmental measures are introduced …
Human bodies as chemical sensors
Recipes for recombining DNA
Laboratory instructions and recipes are sometimes edited into books with a wide circulation. Even in the late twentieth century, publications of this nature remained influential. For example, protocols from a 1980 summer course on gene cloning at Cold Spring Harbor Laboratory provided the basis for a bestselling laboratory manual by Tom Maniatis, Ed Fritsch and Joe Sambrook. Not only did the Molecular Cloning: A Laboratory Manual become a standar…
Learning by the book
This essay offers an overview of how manuals and handbooks have contributed to the standardization, codification, transmission and revision of knowledge. These instructional and reference texts are distinct from related educational genres such as textbooks and editions due to their focus on practical knowledge. They are also notable for their appearance in diverse times and places, such as ancient Greece, early and medieval China and early modern…
Risk on the Table
Risk on the Table
Over the last century, the industrialization of agriculture and processing technologies have made food abundant and relatively inexpensive for much of the world’s population. Simultaneously, pesticides, nitrates, and other technological innovations intended to improve the food supply’s productivity and safety have generated new, often poorly understood risks for consumers and the environment. From the proliferation of synthetic additives to the t…
The molecular vista
This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revit…
Residues
To Test or Not to Test
When the Toxic Substances Control Act (TSCA) was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of indu…
Narratives of Genetic Selfhood
This essay considers the mid‐twentieth century adoption of genetic explanations for three biological phenomena: nutritional adaptation, antibiotic resistance, and antibody production. This occurred at the same time as the hardening of the neo‐Darwinian Synthesis in evolutionary theory. I argue that these concurrent changes reflect an ascendant narrative of genetic selfhood, which prioritized random hereditary variation and selection through compe…
The Story of a Statue
Biology (11 obras) · Computer Science (8 obras) · Political science (8 obras) · Sociology (7 obras) · Genetics (6 obras) · History of Science and Medicine (6 obras) · Law (6 obras) · Philosophy (6 obras) · Art (4 obras) · Epistemology (4 obras)