Antti Latvala
Dados Biográficos
| ID | 1731707 |
|---|---|
| NOME | Antti Latvala |
| PRENOMES | Antti |
| SOBRENOME | Latvala |
| ASSINATURA | LATVALA A |
| AFILIAÇÕES | University of Helsinki |
| ORCID | 0000-0001-5695-117X |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 21 |
| TOTAL DE CITAÇÕES | 8 |
| TOTAL COMO AUTOR | 21 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2013 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 2 |
Neighborhood social structure, criminal convictions, and substance use disorders in Sweden
PURPOSE: We investigated how multidimensional neighborhood types, capturing the complexity of neighborhood social structure, related to criminal convictions and substance use disorders (SUDs) in Sweden while accounting for residential mobility and shared familial influences. METHODS: Using nationwide Swedish register data (1991-2020), we followed 1.82 million individuals born 1985-2002 across five neighborhood types previously identified using la…
Parental incarceration and psychiatric disorders, suicidal behavior, risk‐taking, and substance misuse events in offspring
BACKGROUND: Parental incarceration (PI) is associated with mental and behavioral problems in offspring, but causality remains unclear. We conducted a quasi-experimental within-individual study on the associations of PI with offspring psychiatric disorders, suicidal behavior, risk-taking, and substance misuse events, aiming to test the effect of PI on offspring. METHODS: The study included 43,011 and 5,912 individuals born in Sweden 1973-2010 and …
Mortality in offspring with parental criminal convictions
Background: Parental offending behavior is associated with poorer child mental and physical health, but less in known about its association with child mortality. Further, research is focused on the United States, which is unique in its societal structure and mass incarceration. Methods: Using population-based register data on all births in Sweden in 1973-2013 (N = 4.2 million) and Cox regressions, we examined the associations of mother's and fath…
Neighborhood social structure in Sweden
Background Neighborhoods shape daily life through physical and social structures, such as socioeconomic conditions, population density, and resident turnover. Decades of research link neighborhood characteristics to health and behavioral outcomes. However, these factors are often studied independently, neglecting their interrelated nature. Methods Using Swedish population registry data, we employed latent class analyses to identify neighborhood t…
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are conducted through family-based variance analyses, which are more robust to the systemic biases that impact population-based methods. We combined da…
Causally-informative analyses of the effect of job displacement on all-cause and specific-cause mortality from the 1990s Finnish recession until 2020
Our analyses support the causal influence of job displacement on all-cause and specific-cause mortality, even up to 30 years after the recession; this risk varies by cause of death and by length of follow-up. Future work should evaluate stress and substance use as potential pathways from job displacement to mortality
Health, behavior, and social outcomes among offspring of parents with criminal convictions
BACKGROUND: There is currently insufficient understanding of the health and behavior of children whose parents engage in criminal behavior. We examined associations between parental criminal convictions and wide range of offspring health, behavioral, and social outcomes by age 18 in a large, national sample, aiming to get a comprehensive picture of the risks among children of offending parents. METHODS: We studied 1,013,385 individuals born in Sw…
Parental incarceration and offspring criminality
While parental incarceration (PI) is consistently associated with offspring offending, less is known about possible heterogeneity in the association. We examined associations between PI and offspring crime considering possible moderating factors related to parent's criminality and sociodemographic background. Using Finnish total population data of children born in 1987–2003 ( N = 1,017,072), we conducted Cox regression models for PI by age 18 and…
Evidence for intergenerational transmission of biological risk for antisocial behavior
General and violent recidivism of former forensic psychiatric patients in Finland
The recidivism rate in Finland was markedly lower than has been previously reported for other Western countries, and the mean duration of treatment was also longer. A longer treatment time may reduce the risk of criminal recidivism in forensic psychiatric patients. The results suggest, as previous studies have found, that more effort is indicated on the treatment of substance abuse
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Adverse perinatal events and offspring criminal convictions in men and women
We examined associations of adverse perinatal events with offspring violent and non-violent criminal convictions in men and women. All singleton births between 1973 and 1995 (n = 1,146,570 men, n = 1,085,217 women) were identified through Swedish population-based registers. Information about adverse perinatal events was retrieved from the Medical Birth Register. Outcomes were criminal convictions collected from the National Crime Register. We est…
Parental criminality and children's educational attainment
We examine how parental criminality is associated with offspring education at different educational stages from primary to tertiary education and conduct separate analyses for non-violent and violent crimes and incarceration, and for paternal and maternal criminality. We use Swedish total population register data of 513,886 children and their parents and estimate both population-level linear probability models and cousin fixed-effects models. Par…
Do psychopathic personality traits in childhood predict subsequent criminality and psychiatric outcomes over and above childhood behavioral problems
Parental substance misuse and reproductive timing in offspring
Parents with substance misuse provide their children with a potentially risky rearing environment. According to the evolutionary life history theory, such environments steer individuals towards faster reproductive strategy. However, parents providing their children with hazardous environments may also pass on genes associated with early parenthood. In register data on individuals born in Sweden 1973–1993 (N = 2,176,128), the hazard ratio of enter…
Population-level indicators associated with hormonal contraception use
Sociodemographic differences in relation to HC use exist across Finnish municipalities. Municipal indicators of social structure, health and welfare, and investment in and use of healthcare services are related to HC use
Associations of neighborhood disadvantage and offender concentration with criminal behavior
The association between neighborhood disadvantage and crime has been extensively studied, but most studies have relied on cross-sectional data and have been unable to separate potential effects of the neighborhood from selection effects. We examined how neighborhood disadvantage and offender concentration are associated with criminal behavior while accounting for selection effects due to unobserved time-invariant characteristics of the individual…
Association between birth weight and educational attainment
BACKGROUND: There is evidence that birth weight is positively associated with education, but it remains unclear whether this association is explained by familial environmental factors, genetic factors or the intrauterine environment. We analysed the association between birth weight and educational years within twin pairs, which controls for genetic factors and the environment shared between co-twins. METHODS: The data were derived from nine twin …
Genome-wide association study identifies 74 loci associated with educational attainment
Education and alcohol use
The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may limit or exacerbate an underlying genetic predisposition. However, much of the work on G…
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Education and alcohol use
The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may limit or exacerbate an underlying genetic predisposition. However, much of the work on G…
Adverse perinatal events and offspring criminal convictions in men and women
We examined associations of adverse perinatal events with offspring violent and non-violent criminal convictions in men and women. All singleton births between 1973 and 1995 (n = 1,146,570 men, n = 1,085,217 women) were identified through Swedish population-based registers. Information about adverse perinatal events was retrieved from the Medical Birth Register. Outcomes were criminal convictions collected from the National Crime Register. We est…
Associations of neighborhood disadvantage and offender concentration with criminal behavior
The association between neighborhood disadvantage and crime has been extensively studied, but most studies have relied on cross-sectional data and have been unable to separate potential effects of the neighborhood from selection effects. We examined how neighborhood disadvantage and offender concentration are associated with criminal behavior while accounting for selection effects due to unobserved time-invariant characteristics of the individual…
Association between birth weight and educational attainment
BACKGROUND: There is evidence that birth weight is positively associated with education, but it remains unclear whether this association is explained by familial environmental factors, genetic factors or the intrauterine environment. We analysed the association between birth weight and educational years within twin pairs, which controls for genetic factors and the environment shared between co-twins. METHODS: The data were derived from nine twin …
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Genome-wide association study identifies 74 loci associated with educational attainment
Education and alcohol use
The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may limit or exacerbate an underlying genetic predisposition. However, much of the work on G…
Association between birth weight and educational attainment
BACKGROUND: There is evidence that birth weight is positively associated with education, but it remains unclear whether this association is explained by familial environmental factors, genetic factors or the intrauterine environment. We analysed the association between birth weight and educational years within twin pairs, which controls for genetic factors and the environment shared between co-twins. METHODS: The data were derived from nine twin …
Parental substance misuse and reproductive timing in offspring
Parents with substance misuse provide their children with a potentially risky rearing environment. According to the evolutionary life history theory, such environments steer individuals towards faster reproductive strategy. However, parents providing their children with hazardous environments may also pass on genes associated with early parenthood. In register data on individuals born in Sweden 1973–1993 (N = 2,176,128), the hazard ratio of enter…
Population-level indicators associated with hormonal contraception use
Sociodemographic differences in relation to HC use exist across Finnish municipalities. Municipal indicators of social structure, health and welfare, and investment in and use of healthcare services are related to HC use
Associations of neighborhood disadvantage and offender concentration with criminal behavior
The association between neighborhood disadvantage and crime has been extensively studied, but most studies have relied on cross-sectional data and have been unable to separate potential effects of the neighborhood from selection effects. We examined how neighborhood disadvantage and offender concentration are associated with criminal behavior while accounting for selection effects due to unobserved time-invariant characteristics of the individual…
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Adverse perinatal events and offspring criminal convictions in men and women
We examined associations of adverse perinatal events with offspring violent and non-violent criminal convictions in men and women. All singleton births between 1973 and 1995 (n = 1,146,570 men, n = 1,085,217 women) were identified through Swedish population-based registers. Information about adverse perinatal events was retrieved from the Medical Birth Register. Outcomes were criminal convictions collected from the National Crime Register. We est…
Parental criminality and children's educational attainment
We examine how parental criminality is associated with offspring education at different educational stages from primary to tertiary education and conduct separate analyses for non-violent and violent crimes and incarceration, and for paternal and maternal criminality. We use Swedish total population register data of 513,886 children and their parents and estimate both population-level linear probability models and cousin fixed-effects models. Par…
Do psychopathic personality traits in childhood predict subsequent criminality and psychiatric outcomes over and above childhood behavioral problems
General and violent recidivism of former forensic psychiatric patients in Finland
The recidivism rate in Finland was markedly lower than has been previously reported for other Western countries, and the mean duration of treatment was also longer. A longer treatment time may reduce the risk of criminal recidivism in forensic psychiatric patients. The results suggest, as previous studies have found, that more effort is indicated on the treatment of substance abuse
Health, behavior, and social outcomes among offspring of parents with criminal convictions
BACKGROUND: There is currently insufficient understanding of the health and behavior of children whose parents engage in criminal behavior. We examined associations between parental criminal convictions and wide range of offspring health, behavioral, and social outcomes by age 18 in a large, national sample, aiming to get a comprehensive picture of the risks among children of offending parents. METHODS: We studied 1,013,385 individuals born in Sw…
Parental incarceration and offspring criminality
While parental incarceration (PI) is consistently associated with offspring offending, less is known about possible heterogeneity in the association. We examined associations between PI and offspring crime considering possible moderating factors related to parent's criminality and sociodemographic background. Using Finnish total population data of children born in 1987–2003 ( N = 1,017,072), we conducted Cox regression models for PI by age 18 and…
Evidence for intergenerational transmission of biological risk for antisocial behavior
Neighborhood social structure in Sweden
Background Neighborhoods shape daily life through physical and social structures, such as socioeconomic conditions, population density, and resident turnover. Decades of research link neighborhood characteristics to health and behavioral outcomes. However, these factors are often studied independently, neglecting their interrelated nature. Methods Using Swedish population registry data, we employed latent class analyses to identify neighborhood t…
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are conducted through family-based variance analyses, which are more robust to the systemic biases that impact population-based methods. We combined da…
Causally-informative analyses of the effect of job displacement on all-cause and specific-cause mortality from the 1990s Finnish recession until 2020
Our analyses support the causal influence of job displacement on all-cause and specific-cause mortality, even up to 30 years after the recession; this risk varies by cause of death and by length of follow-up. Future work should evaluate stress and substance use as potential pathways from job displacement to mortality
Neighborhood social structure, criminal convictions, and substance use disorders in Sweden
PURPOSE: We investigated how multidimensional neighborhood types, capturing the complexity of neighborhood social structure, related to criminal convictions and substance use disorders (SUDs) in Sweden while accounting for residential mobility and shared familial influences. METHODS: Using nationwide Swedish register data (1991-2020), we followed 1.82 million individuals born 1985-2002 across five neighborhood types previously identified using la…
Parental incarceration and psychiatric disorders, suicidal behavior, risk‐taking, and substance misuse events in offspring
BACKGROUND: Parental incarceration (PI) is associated with mental and behavioral problems in offspring, but causality remains unclear. We conducted a quasi-experimental within-individual study on the associations of PI with offspring psychiatric disorders, suicidal behavior, risk-taking, and substance misuse events, aiming to test the effect of PI on offspring. METHODS: The study included 43,011 and 5,912 individuals born in Sweden 1973-2010 and …
Mortality in offspring with parental criminal convictions
Background: Parental offending behavior is associated with poorer child mental and physical health, but less in known about its association with child mortality. Further, research is focused on the United States, which is unique in its societal structure and mass incarceration. Methods: Using population-based register data on all births in Sweden in 1973-2013 (N = 4.2 million) and Cox regressions, we examined the associations of mother's and fath…
Psychology (12 obras) · Demography (11 obras) · Biology (10 obras) · Medicine (10 obras) · Population (9 obras) · Demography (8 obras) · Offspring (8 obras) · Genetics (7 obras) · Genetics (7 obras) · Poison control (7 obras)