Kawango Agot
Dados Biográficos
| ID | 1734165 |
|---|---|
| NOME | Kawango Agot |
| PRENOMES | Kawango |
| SOBRENOME | Agot |
| ASSINATURA | AGOT K |
| AFILIAÇÕES | Impact Research and Development Organization |
| ORCID | 0000-0002-6153-8950 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 48 |
| TOTAL DE CITAÇÕES | 5 |
| TOTAL COMO AUTOR | 48 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2007 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 1 |
Systematic dissemination of study findings from local to national stakeholders
Disseminating research findings to potential beneficiaries such as study participants, community members, and stakeholders is a critical component of participatory research. While there is general agreement that dissemination is critical, documented examples of comprehensive dissemination activities are few in the literature. We present a concrete example of a multi-level stakeholder dissemination process from a successful HIV self-testing and li…
Motivations for testing and linkage to HIV services following HIV self-testing among fishermen in Kenya
HIV self-testing (HIVST) is a promising strategy to expand testing access for hard-to-reach populations such as Kenyan fishermen. We examined motivations and barriers to HIVST use and linkage to HIV prevention and treatment services (including PrEP or ART), within a social network-based intervention (NCT04772469). We conducted interviews (N = 64) and focus group discussions (N = 4) with fishermen in Siaya County, including 30 “promoters” who dist…
“Money is everything. If you don’t have cash, no one will come to you
Previous studies have reported a positive association between socioeconomic status (SES) and HIV infection in sub-Saharan Africa (SSA). This contradicts widespread understandings of how health disparities are created and sustained through socioeconomic disparity. The nature of high HIV prevalence in SSA among wealthier individuals, especially those aged 15–24 who experience wealth and HIV risk differently than other age groups, is less understood…
Behavioral and Structural Interventions for PrEP Adherence Among Young Female Sex Workers from Western Kenya
HIV incidence is high among young female sex workers (YFSW) in Kenya. Pre-exposure prophylaxis (PrEP) for HIV prevention is recommended for at-risk populations, but its effectiveness requires consistent access and adherence. The IPrEP study compared the feasibility, acceptability, and effectiveness of two adherence support interventions on PrEP adherence among YFSW in Kisumu, Kenya. Study follow-up coincided with national restrictions on travel a…
Comparing comprehension of consent document between adolescent girls and caregivers of adolescents in Siaya County, Kenya
Despite their vulnerability, adolescents are often excluded from health research due to ethical concerns about research with minors, especially in low-income regions like Sub-Saharan Africa. We enrolled adolescent girls aged 15–17 years and caregivers of girls of the same age. Using a 25-question Comprehension Score Sheet, we applied a quantitative approach to compare the comprehension of informed consent of 33 adolescent girls and 41 caregivers …
Misconceptions and limited experience with HIV pre-exposure prophylaxis (PrEP) among fishermen in Western Kenya
Daily oral HIV pre-exposure prophylaxis (PrEP) is highly effective when taken consistently, but its uptake remains low among mobile fishermen in Kenya. This study explored barriers and facilitators to PrEP uptake in three Lake Victoria beach communities. In-depth interviews (IDIs) and focus group discussions (FGDs) were conducted with 65 fishermen, purposively sampled by community, age and study arm. IDIs and FGDs examined PrEP knowledge, percept…
Comparing PrEP adherence via objective and self-reported measures among fishermen working on Lake Victoria, Kenya
Fishermen working along Lake Victoria experience high rates of HIV acquisition that can be mitigated by pre-exposure prophylaxis (PrEP), which requires adequate adherence for effective prevention. We evaluated PrEP adherence among Kenyan fishermen using objective metrics and examine non-adherence. Data are from the Owete study (NCT04772469), a cluster randomized-controlled trial using a social network approach among fishermen to increase HIV test…
Health promotion messaging reduces HIV risk behaviours and improves repeat testing among adolescent girls and young women in Kenya
Adolescents and young people in sub-Saharan Africa account for about a third of persons newly diagnosed with HIV. Health communication, through mobile health (mHealth) can improve access to sexual and reproductive health information, health services and reduce risky sexual behaviours among adolescents and young people. We assessed the impact of a health promotion messaging intervention on the reduction of risky sexual behaviours among HIV-negativ…
Saving for a rainy day
Financial insecurity pushes female sex workers into risky sexual transactions. We piloted an economic empowerment intervention among female sex workers in Kenya to test if they could save part of their income from which to make withdrawals to avoid risky sexual encounters. We enrolled female sex workers and randomised half to the intervention arm, who were given instructions on how to save and withdraw money through a mobile platform, and half to…
High mortality among fishermen along the beaches of lake Victoria
The causes of death were varied, underscoring the need for a multi-disease approach to address the health risks in high-risk occupations like fishing. Since HIV is one of several significant health threats to fishermen, efforts to end HIV must also address other life-threatening conditions
There is no need to leave the beach to test”
While few fishermen had ever used HIVST, this study found high awareness, positive perceptions, and substantial willingness to use and distribute HIVST to other men. The "promoter" model, with known peers engaged in disseminating HIVST information and test kits, shows promise for engaging men in testing
Gaps in Effective HIV Pre-exposure Prophylaxis Screening and Uptake Among Fishermen in Kenya
Despite oral daily HIV pre-exposure prophylaxis (PrEP) effectiveness, uptake remains a challenge. Awareness of one's HIV status and engagement in prevention is essential to interrupting transmission among populations at high risk of HIV. We explored gaps in HIV risk perception, screening, and PrEP uptake among high HIV-risk fishermen living and working along Lake Victoria, Kenya. Data are from the Owete study (NCT04772469), which evaluated the im…
Shifting reasons for older men remaining uncircumcised
Voluntary medical male circumcision (VMMC) reduces men’s risk of acquiring Human immunodeficiency virus (HIV) through vaginal sex. However, VMMC uptake remains lowest among Kenyan men ages 25–39 years among whom the impact on reducing population-level HIV incidence was estimated to be greatest at the start of the study in 2014. We conducted a pre- and post-intervention survey as part of a cluster randomized controlled trial to determine the effec…
Training Social Network-Central Fishermen in Western Kenya to Distribute HIV Self-Test Kits and Health Facility Referral Vouchers
Low HIV testing among men, particularly highly mobile fishermen, is a persistent challenge. The Owete study (NCT#04772469) used social network-central men (Promoters) to promote testing and linkage to HIV services among social networks of fishermen in western Kenya. The Promoters and fishermen networks were randomised to intervention or control arms. We describe Owete's interactive training approach and Promoters' training experiences for impleme…
Facility characteristics preferred by older men seeking medical male circumcision services in Kenya
Primary healthcare facilities are central to the implementation of voluntary medical male circumcision (VMMC) as points of access to integrated health services in line with the Kenya AIDS Strategic Framework II (2020/21-2024/25). Knowledge of factors that explain men's uptake of VMMC and sexual health services at these facilities and preferences of where to get the services remain poorly understood. Using qualitative methodologies, we examined fa…
Jitegemee (rely on yourself)
A savings intervention for and by FSW was highly acceptable and feasible. Involving end-users in the design process is likely to result in greater economic security among FSW and lower engagement in higher risk transactional sex
Feasibility and Acceptability of the Novel Tu’Washindi Intervention to Increase PrEP Use among Adolescent Girls and Young Women in Siaya County, Kenya
The Tu'Washindi intervention addressed intimate partner violence (IPV) and relationship dynamics to increase PrEP use among adolescent girls and young women (AGYW) in Siaya County, Kenya. We evaluated feasibility and acceptability in a cluster-randomized trial in six DREAMS Safe Spaces. The multilevel intervention, delivered over 6 months, included three components delivered by DREAMS staff with support from the study team: an 8-session structure…
‘I feel that I should decide on my own….’
INTRODUCTION: Efforts to improve health outcomes among adolescents and young adults living with HIV (ALHs) are hampered by limited adolescent engagement in HIV-related research. We sought to understand the views of adolescents, caregivers and healthcare workers (HCWs) about who should make decisions regarding ALHs' research participation. METHODS: We conducted focus group discussions (FGDs) and in-depth interviews (IDIs) with ALHs (aged 14-24 yea…
Navigating antiretroviral adherence in boarding secondary schools in Nairobi, Kenya
In Kenya, adolescents spend much of their formative years in boarding secondary schools, which presents a challenging environment for antiretroviral (ART) adherence support among adolescents living with HIV (ALHIV). We examined the experiences of ALHIV, caregivers of adolescents, and school nurses regarding navigating ART adherence in boarding secondary schools. Between July and November 2022, we conducted focus group discussions (FGDs) among ALH…
Early infant male circumcision
Introduction : Traditional male circumcision (TMC) inculcates masculine-dominance norms in young men. Early infant male circumcision (EIMC) and medical male circumcision (MMC) can potentially minimise these adverse gender norms. We explored the perceptions about EIMC and MMC among communities practising TMC in Kenya. Method: We conducted focus group discussions with men and women and councils of elders, and key informant interviews with tradition…
Individual-, Interpersonal- and Institutional-Level Factors Associated with HIV Stigma Among Youth in Kenya
Formative assessment to identify perceived benefits and barriers of HIV oral self-testing among female sex workers, service providers, outreach workers, and peer educators to inform scale-up in Kenya
In Kenya, HIV prevalence estimates among female sex workers (FSWs) are almost five times higher than among women in the general population. However, only 68% of infected FSWs are aware of their HIV-positive status. We aimed to identify perceived benefits, opportunities, and barriers of HIV self-testing (HIVST) in improving testing coverage among FSWs. Twenty focus group discussions were conducted with 77 service providers, 42 peer educators (PEs)…
‘When I have these kits … I have confidence’ – HIV self-testing provides agency for women in their sexual decision-making
Oral fluid-based HIV self-testing (HIVST) has emerged as a promising approach to increasing HIV testing coverage, particularly among high-risk populations. Understanding the experiences of women using self-tests and offering them to their sexual partners (secondary distribution) is crucial for determining the potential of HIVST. Qualitative in-depth interviews were conducted among 32 women at high risk of HIV infection, including women who engage…
I didn’t support PrEP because I didn’t know what it was ”
The HIV infection rate is higher among adolescent girls and young women (AGYW) in Africa than men in the same age range. Pre-exposure prophylaxis (PrEP) can be used by women discreetly; however, for most AGYW, male partner approval is desired. We explored PrEP use in the context of relationship violence and power dynamics through focus group discussions and support club sessions with AGYW, in-depth interviews and male sensitisation sessions with …
Mapping geographic clusters of new HIV diagnoses to inform granular-level interventions for HIV epidemic control in western Kenya
Our study used routine public health program data to identify granular geographic clusters of higher new HIV diagnoses, and sub-populations with higher HIV-positive yield in the setting of a generalized HIV epidemic. In order to target HIV testing and prevention interventions to finer granular geographic areas for maximal epidemiologic impact, integrating geospatial analysis into routine public health programs can be useful
This is the medicine
We report the results of the first study designed to evaluate the feasibility and acceptability of an HIV prevention intervention focused on concurrent sexual partnerships. Mathematical models and longitudinal studies of stable couples indicate concurrency plays a critical role in sustaining generalized HIV epidemics in heterosexual populations, and East and Southern African nations identified concurrency reduction as a priority for HIV preventio…
Male circumcision for HIV prevention in young men in Kisumu, Kenya
Determinants of Consistent Condom Use Vary by Partner Type among Young Men in Kisumu, Kenya
Scaling Sexual Behavior or “Sexual Risk Propensity” Among Men at Risk for HIV in Kisumu, Kenya
Scaling Sexual Behavior or “Sexual Risk Propensity” Among Men at Risk for HIV in Kisumu, Kenya
Factors Associated with the Early Resumption of Sexual Activity Following Medical Male Circumcision in Nyanza Province, Kenya
Preexposure Prophylaxis for HIV Infection among African Women
BACKGROUND: Preexposure prophylaxis with antiretroviral drugs has been effective in the prevention of human immunodeficiency virus (HIV) infection in some trials but not in others. METHODS: In this randomized, double-blind, placebo-controlled trial, we assigned 2120 HIV-negative women in Kenya, South Africa, and Tanzania to receive either a combination of tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) or placebo once daily. The primary…
Circumcision preference among women and uncircumcised men prior to scale-up of male circumcision for HIV prevention in Kisumu, Kenya
Following the endorsement by the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) of male circumcision as an additional strategy to HIV prevention, initiatives to introduce safe, voluntary medical male circumcision (VMMC) services commenced in 2008 in several sub-Saharan African communities. Information regarding perceptions of circumcision as a method of HIV prevention, however, is largely limited to da…
“It is all about the fear of being discriminated [against]…the person suffering from HIV will not be accepted”
Interventions focusing on reduction of stigma, increasing safe disclosure of HIV status, and improved dependent relationships may improve retention in care of YLWH
Risk Compensation Following Male Circumcision
Accuracy of Self-Report and Pill-Count Measures of Adherence in the FEM-PrEP Clinical Trial
Oral emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) has been evaluated as pre-exposure prophylaxis (PrEP). We describe the accuracy of self-reported adherence to FTC/TDF and pill counts when compared to drug concentrations in the FEM-PrEP trial. Using drug concentrations of plasma tenofovir (TFV) and intracellular tenofovir diphosphate (TFVdp) among a random sub-sample of 150 participants assigned to FTC/TDF, we estimated the positive pred…
This is the medicine
We report the results of the first study designed to evaluate the feasibility and acceptability of an HIV prevention intervention focused on concurrent sexual partnerships. Mathematical models and longitudinal studies of stable couples indicate concurrency plays a critical role in sustaining generalized HIV epidemics in heterosexual populations, and East and Southern African nations identified concurrency reduction as a priority for HIV preventio…
Reprint of
Promoting Partner Testing and Couples Testing through Secondary Distribution of HIV Self-Tests
BACKGROUND: Achieving higher rates of partner HIV testing and couples testing among pregnant and postpartum women in sub-Saharan Africa is essential for the success of combination HIV prevention, including the prevention of mother-to-child transmission. We aimed to determine whether providing multiple HIV self-tests to pregnant and postpartum women for secondary distribution is more effective at promoting partner testing and couples testing than …
Promoting male partner HIV testing and safer sexual decision making through secondary distribution of self-tests by HIV-negative female sex workers and women receiving antenatal and post-partum care i…
Loss to follow-up among youth accessing outpatient HIV care and treatment services in Kisumu, Kenya
Youth are particularly vulnerable to acquiring HIV, yet reaching them with HIV prevention interventions and engaging and retaining those infected in care and treatment remains a challenge. We sought to determine the incidence rate of loss to follow-up (LTFU) and explore socio-demographic and clinical characteristics associated with LTFU among HIV-positive youth aged 15-21 years accessing outpatient care and treatment clinics in Kisumu, Kenya. Bet…
When and why women might suspend PrEP use according to perceived seasons of risk
Oral pre-exposure prophylaxis (PrEP) using the antiretroviral drug emtricitabine/tenofovir disoproxil fumarate (Truvada) has been shown to dramatically reduce the risk of HIV acquisition for women at higher risk of infection if taken daily. Understanding when and why women would intentionally stop using an efficacious oral PrEP drug within the context of their 'normal' daily lives is essential for delivering effective PrEP risk-reduction counsell…
An ethnographic exploration of drug markets in Kisumu, Kenya
Prevalence and Predictors of Uncircumcised, Kenyan Men’s Desire for Circumcision for Their Infant Sons
End-Users’ Product Preference Across Three Multipurpose Prevention Technology Delivery Forms
A multipurpose prevention technology (MPT) that combines HIV and pregnancy prevention is a promising women's health intervention, particularly for young women. However, little is known about the drivers of acceptability and product choice for MPTs in this population. This paper explores approval ratings and stated choice across three different MPT delivery forms among potential end-users. The Trio Study was a mixed-methods study in women ages 18-…
Perspectives on biomedical HIV prevention options among women who inject drugs in Kenya
Due to heightened vulnerability to HIV from frequent engagement in sex work and overlapping drug-using and sexual networks, women who inject drugs should be a high priority population for pre-exposure prophylaxis (PrEP) and other biomedical HIV prevention tools. Kenya is one of the first African countries to approve oral PrEP for HIV prevention among "key populations," including people who inject drugs and sex workers. The objective of this study…
Young Women’s Ratings of Three Placebo Multipurpose Prevention Technologies for HIV and Pregnancy Prevention in a Randomized, Cross-Over Study in Kenya and South Africa
End-user input is critical to inform development of multipurpose prevention technology (MPT) products that prevent HIV and pregnancy. The TRIO Study, conducted in Kenya and South Africa, enrolled 277 HIV-negative women aged 18-30 in a randomized cross-over study to use each placebo MPT (daily oral tablets, monthly injections, and monthly vaginal ring) for one month. At the end of each month, participants rated how much they liked using the produc…
The Psychosocial Effects of the Covid-19 Pandemic on Youth Living with HIV in Western Kenya
The objective of this study was to assess psychosocial effects of COVID-19 among adolescents living with HIV (ALHIV) in Kenya and to assess the feasibility of conducting behavioral surveys by phone. We adapted our protocol to administer telephone rather than in-person follow-up surveys and included questions about COVID-19. The majority of participants (99%) reported having heard of COVID-19; 23% reported no longer being able to go outside, 17% r…
Mapping geographic clusters of new HIV diagnoses to inform granular-level interventions for HIV epidemic control in western Kenya
Our study used routine public health program data to identify granular geographic clusters of higher new HIV diagnoses, and sub-populations with higher HIV-positive yield in the setting of a generalized HIV epidemic. In order to target HIV testing and prevention interventions to finer granular geographic areas for maximal epidemiologic impact, integrating geospatial analysis into routine public health programs can be useful
Life in the Balance
Formative assessment to identify perceived benefits and barriers of HIV oral self-testing among female sex workers, service providers, outreach workers, and peer educators to inform scale-up in Kenya
In Kenya, HIV prevalence estimates among female sex workers (FSWs) are almost five times higher than among women in the general population. However, only 68% of infected FSWs are aware of their HIV-positive status. We aimed to identify perceived benefits, opportunities, and barriers of HIV self-testing (HIVST) in improving testing coverage among FSWs. Twenty focus group discussions were conducted with 77 service providers, 42 peer educators (PEs)…
Medicine (43 obras) · Family medicine (33 obras) · HIV/AIDS Research and Interventions (33 obras) · Adolescent Sexual and Reproductive Health (24 obras) · Nursing (24 obras) · Public health (22 obras) · Environmental health (20 obras) · Psychology (20 obras) · Population (17 obras) · Demography (16 obras)