Markus Perola
Dados Biográficos
| ID | 1912667 |
|---|---|
| NOME | Markus Perola |
| PRENOMES | Markus |
| SOBRENOME | Perola |
| ASSINATURA | PEROLA M |
| AFILIAÇÕES | University of Helsinki |
| ORCID | 0000-0003-4842-1667 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 13 |
| TOTAL DE CITAÇÕES | 44 |
| TOTAL COMO AUTOR | 13 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2003 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2023 |
| ÍNDICE H | 3 |
Nationwide health, socio-economic and genetic predictors of Covid-19 vaccination status in Finland
Understanding factors associated with COVID-19 vaccination can highlight issues in public health systems. Using machine learning, we considered the effects of 2,890 health, socio-economic and demographic factors in the entire Finnish population aged 30–80 and genome-wide information from 273,765 individuals. The strongest predictors of vaccination status were labour income and medication purchase history. Mental health conditions and having unvac…
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Genetics in an isolated population like Finland
A unique genetic background in an isolated population like that of Finland offers special opportunities for genetic research as well as for applying the genetic developments to the health care. On the other hand, the different genetic background may require local attempts to develop diagnostics and treatment as the selection of diseases and mutations differs from that in the other populations. In this review, we describe the experiences of resear…
Genetic evidence of assortative mating in humans
Genome-wide association study identifies 74 loci associated with educational attainment
Genetic studies of body mass index yield new insights for obesity biology
Genetic causal beliefs about morbidity
Despite increased public discussion of genomics, the relative proportion of those who endorse genetic factors as the most important cause of morbidity has remained low. However, within this group beliefs about benefits of health behavior changes have become more positive. This could indicate that increase in genomic health information does not lead to more negative appraisals of efficacy of lifestyle changes
Identifying flavor preference subgroups. Genetic basis and related eating behavior traits
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Genetic contribution to sour taste preference
Food neophobia in young adults. Genetic architecture and relation to personality, BMI, and pleasantness and use frequency of foods
Heritability of Adult Body Height
A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic architecture of body height varies between affluent western societies. We analysed twin data from eight countries comprising 30,111 complete twin pairs by using the univariate genetic model of the Mx statistical package. Body height and zygosity were se…
Genetic evidence of assortative mating in humans
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Identifying flavor preference subgroups. Genetic basis and related eating behavior traits
Genetic contribution to sour taste preference
Nationwide health, socio-economic and genetic predictors of Covid-19 vaccination status in Finland
Understanding factors associated with COVID-19 vaccination can highlight issues in public health systems. Using machine learning, we considered the effects of 2,890 health, socio-economic and demographic factors in the entire Finnish population aged 30–80 and genome-wide information from 273,765 individuals. The strongest predictors of vaccination status were labour income and medication purchase history. Mental health conditions and having unvac…
Heritability of Adult Body Height
A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic architecture of body height varies between affluent western societies. We analysed twin data from eight countries comprising 30,111 complete twin pairs by using the univariate genetic model of the Mx statistical package. Body height and zygosity were se…
Food neophobia in young adults. Genetic architecture and relation to personality, BMI, and pleasantness and use frequency of foods
Genetic contribution to sour taste preference
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Identifying flavor preference subgroups. Genetic basis and related eating behavior traits
Genetic studies of body mass index yield new insights for obesity biology
Genetic causal beliefs about morbidity
Despite increased public discussion of genomics, the relative proportion of those who endorse genetic factors as the most important cause of morbidity has remained low. However, within this group beliefs about benefits of health behavior changes have become more positive. This could indicate that increase in genomic health information does not lead to more negative appraisals of efficacy of lifestyle changes
Genome-wide association study identifies 74 loci associated with educational attainment
Genetics in an isolated population like Finland
A unique genetic background in an isolated population like that of Finland offers special opportunities for genetic research as well as for applying the genetic developments to the health care. On the other hand, the different genetic background may require local attempts to develop diagnostics and treatment as the selection of diseases and mutations differs from that in the other populations. In this review, we describe the experiences of resear…
Genetic evidence of assortative mating in humans
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Nationwide health, socio-economic and genetic predictors of Covid-19 vaccination status in Finland
Understanding factors associated with COVID-19 vaccination can highlight issues in public health systems. Using machine learning, we considered the effects of 2,890 health, socio-economic and demographic factors in the entire Finnish population aged 30–80 and genome-wide information from 273,765 individuals. The strongest predictors of vaccination status were labour income and medication purchase history. Mental health conditions and having unvac…
Biology (10 obras) · Genetic Associations and Epidemiology (7 obras) · Gene (5 obras) · Genetics (5 obras) · Environmental health (4 obras) · Genetics (4 obras) · Medicine (4 obras) · Population (4 obras) · Birth, Development, and Health (3 obras) · Computational biology (3 obras)