Sachin H Mehta
Dados Biográficos
| ID | 230694 |
|---|---|
| NOME | Sachin H Mehta |
| PRENOMES | Sachin H |
| SOBRENOME | Mehta |
| ASSINATURA | MEHTA S H |
| AFILIAÇÕES | Johns Hopkins University |
| ORCID | 0000-0002-2523-0959 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 49 |
| TOTAL DE CITAÇÕES | 24 |
| TOTAL COMO AUTOR | 49 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2007 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 3 |
Characterizing the Geography of Drug Use Networks and Behaviors Among People Who Inject Drugs in the Baltimore Metropolitan Region
The geography of injection drug use in the United States continues to evolve and expand outside of urban areas, yet there is little understanding of the extent to which urban and non-urban networks of people who inject drugs (PWID) interact, which has implications for HIV and hepatitis C transmission (HCV). Here, we characterize individuals with mixed geography PWID networks in the Baltimore, Maryland region, as well as prospective associations w…
“Especially Being Homeless, They Just Think You’re Infected with Covid or Something”
People experiencing homelessness with a substance use disorder are a highly structurally vulnerable population, facing a unique burden of compounding stigma, discrimination, and adverse health outcomes. Evidence remains mixed on best practices for housing interventions designed to best meet the needs of this population. Ten people with a history of injection drug use experiencing homelessness during the COVID-19 pandemic were interviewed between …
‘ They just kind of disappeared’
Background Social networks shape substance use behaviors and health outcomes among people who inject drugs (PWID), yet the ways in which large-scale crises influence network dynamics, particularly through positive changes, remains underexplored. We examine the COVID-19 pandemic’s impact on social networks of PWID and subsequent changes to substance use behaviors.Methods Twenty-eight in-depth interviews were conducted between July 2021 and Februar…
Concurrent Use of Extra‐Medical Medication for Opioid Use Disorder Among Adults Prescribed Methadone or Buprenorphine
HIV Testing Service Utilization Among Transgender Communities
What, how, and when matters
HIV pre-exposure prophylaxis (PrEP), particularly long-acting injectable formulations (LAI PrEP), has the potential to reduce the number of new infections among people who inject drugs (PWID), especially in low resource settings in the context of low coverage of harm reduction services, high HIV incidence, and substance use and instability. Few studies have examined PrEP perceptions, preferences, and service delivery models among these population…
Impact of Social Drivers of Health, Self-Efficacy, and Substance Use on Covid-19 Preventative Behaviors Among Persons Who Inject Drugs with Hepatitis C
Greater SDoH difficulties and lower self-efficacy were associated with greater inability to practice COVID-19 personal protective behaviors. Interventions to meet SDoH-related challenges and increase self-efficacy could help encourage practice of personal protective behaviors and economically reduce disease burden during health crises
Characterizing non-fatal overdose among people who inject drugs in India
We observed a variable burden of non-fatal overdose associated with high injection frequency, combination drug use, alcohol use, attending medical detoxification, and depressive symptoms. Low levels of subsequent linkage to treatment services suggest opportunities to improve overdose prevention and management
People who inject drugs and men who have sex with men living with HIV in India experience low probability of viral rebound and high levels of persistent viremia during the first 12 months of antiretro…
People who inject drugs (PWID) and men who have sex with men (MSM) in India are disproportionately affected by HIV and experience challenges achieving sustained viral suppression. We evaluated probabilities of suppression over time and characteristics associated with persistent viremia and viral rebound among MSM and PWID living with HIV (PLHIV) using 12 months of data collected between 2017-2019 from a cluster-randomized trial across 16 cities i…
Cesarean Delivery Outcomes for Patients with Coronavirus Disease-2019 in the USA
Drug treatment and support service utilization amidst the Covid-19 pandemic among people who inject drugs in Baltimore, Maryland
Drug Use-Related Discrimination in Healthcare Settings and Subsequent Emergency Department Utilization in a Prospective Cohort Study of People With a History of Injection Drug Use
BACKGROUND: People with a history of injection drug use face discrimination in healthcare settings that may impede their use of routine care, leading to greater reliance on the emergency department (ED) for addressing health concerns. The relationship between discrimination in healthcare settings and subsequent ED utilization has not been established in this population. METHODS: This analysis used longitudinal data collected between January 2014 …
Relationship between patient activation and utilisation of health care and harm reduction services among people who inject drugs in Baltimore, Maryland
Longitudinal patterns of use of stimulants and opioids in the Aids linked to the IntraVenous experience cohort, 2005–2019
High hepatitis C virus reinfection in a community-based sample of people who inject drugs in Imphal, India
Self-reported and measured adherence to hepatitis C direct-acting antiviral therapy and sustained virologic response among people who inject drugs
Fine scale human mobility changes within 26 US cities in 2020 in response to the Covid-19 pandemic were associated with distance and income
Human mobility patterns changed greatly due to the COVID-19 pandemic. Despite many analyses investigating general mobility trends, there has been less work characterising changes in mobility on a fine spatial scale and developing frameworks to model these changes. We analyse zip code-level within-city mobility data from 26 US cities between February 2 –August 31, 2020. We use Bayesian models to characterise the initial decrease in mobility and mo…
Changes in HIV care continuum indicators among community-based samples of HIV-infected people who inject drugs and men who have sex with men across 21 cities in India
Monitoring key populations’ progress towards UNAIDS 90-90-90 targets is essential to achieving HIV/AIDS epidemic control. Using serial cross-sectional data, we evaluated changes in HIV care continuum among people who inject drugs(PWID) and men who have sex with men(MSM) in India. Cross-sectional baseline (2012/2013) and follow-up (2016/2017) samples were recruited using respondent-driven sampling across 21 cities. All participants were tested for…
Trajectories of drug treatment and illicit opioid use in the Aids Linked to the IntraVenous Experience cohort, 2014–2019
Adverse childhood experiences and comorbidity in a cohort of people who have injected drugs
Among people who have injected drugs, adverse childhood experiences were common and associated with increased occurrence of self-reported medical comorbidities. Findings highlight the persistent importance of adversity for physical health even in a population where all members have used drugs and there is a high burden of comorbidity
Substance use is associated with condomless anal intercourse among men who have sex with men in India
To reduce HIV transmission among this population of MSM across India, combination interventions are likely needed. Interventions targeting substance use and education as well as initiatives to increase self-testing are urgently needed among MSM in India and have the potential to reduce HIV transmission in this high-risk population. Trial registration ClinicalTrials.gov Identifier: NCT01686750. Date of Registration: September 18, 2012
Mortality by cause of death during year 1 of the Covid-19 pandemic in a cohort of older adults from Baltimore Maryland who have injected drugs
Drug use stigma and its association with active hepatitis C virus infection and injection drug use behaviors among community-based people who inject drugs in India
Exploring multilevel determinants of co-occurring violence, HIV, mental health and substance use problems
Multiple factors contribute to co-occurring issues such as violence, HIV, and mental disorders among people who inject drugs (PWID), particularly those residing in limited resource settings. Using an ecological framework, this study explored multilevel determinants of co-occurring violence, HIV, mental health, and substance use issues among PWID. Data were collected via semi-structured in-depth interviews with 31 men and women PWID in India. Find…
The use of mobile phone data to inform analysis of Covid-19 pandemic epidemiology
The ongoing coronavirus disease 2019 (COVID-19) pandemic has heightened discussion of the use of mobile phone data in outbreak response. Mobile phone data have been proposed to monitor effectiveness of non-pharmaceutical interventions, to assess potential drivers of spatiotemporal spread, and to support contact tracing efforts. While these data may be an important part of COVID-19 response, their use must be considered alongside a careful underst…
Is there synergy in syndemics? Psychosocial conditions and sexual risk among men who have sex with men in India
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Followin…
Perspectives on Sexual Identity Formation, Identity Practices, and Identity Transitions Among Men Who Have Sex With Men in India
Application of Space-Time Scan Statistics to Describe Geographic and Temporal Clustering of Visible Drug Activity
The association between neighborhood residential rehabilitation and injection drug use in Baltimore, Maryland, 2000–2011
Factors associated with the perpetration of sexual violence among wine-shop patrons in Chennai, India
Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users
We examined the prevalence and prognostic value of early responses to highly active antiretroviral therapy (HAART) among community-based injection drug users (IDUs) in Baltimore. Virologic (HIV RNA 500 cells/ul or increase of 50 cells/ul from the pre-HAART level) responses were examined in the 1st year of HAART initiation. Cox regression was used to examine the effect of early response on progression to new AIDS diagnosis or AIDS-related death. A…
The Emerging HIV Epidemic among Men Who have Sex with Men in Tamil Nadu, India
HIV and COPD
Factors associated with the perpetration of sexual violence among wine-shop patrons in Chennai, India
The intersection between sex and drugs
Our finding of a 10-fold higher HIV prevalence among spouses of IDUs compared with general population women indicates their vulnerability; prevalence is likely to increase given the context of low condom use and frequent sexual violence. Prevention efforts directed at IDUs should also include programs for spouses
High Pregnancy Intentions and Missed Opportunities for Patient–Provider Communication About Fertility in a South African Cohort of HIV-Positive Women on Antiretroviral Therapy
Impact of generic antiretroviral therapy (ART) and free ART programs on time to initiation of ART at a tertiary HIV care center in Chennai, India
Antiretroviral therapy (ART) access in the developing world has improved, but whether increased access has translated to more rapid treatment initiation among those who need it is unknown. We characterize time to ART initiation across three eras of ART availability in Chennai, India (1996-1999: pregeneric; 2000-2003: generic; 2004-2007: free rollout). Between 1996 and 2007, 11,171 patients registered for care at the YR Gaitonde Centre for AIDS Re…
Everything that looks good ain’t good!”
Level of Adherence and HIV RNA Suppression in the Current Era of Highly Active Antiretroviral Therapy (Haart)
The association between neighborhood residential rehabilitation and injection drug use in Baltimore, Maryland, 2000–2011
Application of Space-Time Scan Statistics to Describe Geographic and Temporal Clustering of Visible Drug Activity
Diverse Rates of Depression Among Men Who Have Sex with Men (MSM) Across India
Getting to 90
UNAIDS set an ambitious target of "90-90-90" by 2020. The first 90 being 90% of those HIV-infected will be diagnosed; the second 90 being 90% of those diagnosed will be linked to medical care and on antiretroviral therapy (ART). While there has been dramatic improvement in HIV testing and ART use, substantial losses continue to occur at linkage-to-care following HIV diagnosis. Data on linkage among men who have sex with men (MSM) and people who i…
The prevalence and impact of childhood sexual abuse on HIV-risk behaviors among men who have sex with men (MSM) in India
This large, mixed-methods study found high overall prevalence of CSA among MSM (22.4 %), with substantially higher prevalence among MSM residing in the South and among more feminine sexual identities. Qualitative findings highlighted boys' vulnerabilities to CSA, especially gender nonconformity, and CSA's role in further sexual encounters, including sex work. Additionally, CSA was associated with an elevated rate of recent, and an even higher rat…
Incarceration history and risk of HIV and hepatitis C virus acquisition among people who inject drugs
The impact of a private-public partnership delivery system on the HIV continuum of care in a South Indian city
We characterized the impact of a Private-Public Partnership (PPP) on the continuum of HIV care (e.g., treatment initiation, ART effectiveness and loss to follow-up) among adults enrolled at a private hospital/ART link center in the southern state of Karnataka, India from 2007 through 2012. Data on 2326 adults in care were compiled using an electronic database supplemented with medical chart abstraction. Survival methods with staggered entries wer…
HIV risks among women who are married to men who have sex with men in India
In countries such as India, men who have same-sex partnerships may marry women due to cultural pressures regardless of their sexual desires and preferences. The wives of such men may be at risk for HIV but limited existing research addresses this issue. This qualitative study used in-depth interviews to investigate HIV-related risk among married men who have sex with men (n = 34) and women who were aware of their husband's same-sex behaviour (n =…
Overlap between harm reduction and HIV service utilisation among PWID in India
Hepatitis C care continuum and associated barriers among people who inject drugs in Chennai, India
An Education and Field Experience Program to Increase Detection of Human Immunodeficiency Virus and Hepatitis C Virus
Generation Tomorrow has been successful in engaging students and community peers in HIV and HCV education, testing, and counseling, and has documented HIV and HCV positivity rates well above general community prevalence
Perspectives on Sexual Identity Formation, Identity Practices, and Identity Transitions Among Men Who Have Sex With Men in India
Is there synergy in syndemics? Psychosocial conditions and sexual risk among men who have sex with men in India
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Followin…
Recent fentanyl use among people who inject drugs
The use of mobile phone data to inform analysis of Covid-19 pandemic epidemiology
The ongoing coronavirus disease 2019 (COVID-19) pandemic has heightened discussion of the use of mobile phone data in outbreak response. Mobile phone data have been proposed to monitor effectiveness of non-pharmaceutical interventions, to assess potential drivers of spatiotemporal spread, and to support contact tracing efforts. While these data may be an important part of COVID-19 response, their use must be considered alongside a careful underst…
Individual and network factors associated with HCV treatment uptake among people who inject drugs
Medicine (41 obras) · HIV, Drug Use, Sexual Risk (36 obras) · HIV/AIDS Research and Interventions (25 obras) · Demography (22 obras) · Internal Medicine (21 obras) · Psychiatry (20 obras) · Human immunodeficiency virus (HIV (17 obras) · Environmental health (16 obras) · Demography (15 obras) · Family medicine (14 obras)