K Rivet Amico
Dados Biográficos
| ID | 238389 |
|---|---|
| NOME | K Rivet Amico |
| PRENOMES | K Rivet |
| SOBRENOME | Amico |
| ASSINATURA | AMICO K R |
| AFILIAÇÕES | University of Michigan |
| ORCID | 0000-0002-4458-6934 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 95 |
| TOTAL DE CITAÇÕES | 12 |
| TOTAL COMO AUTOR | 95 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2005 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 2 |
A Narrative Review of Remote Biospecimen Collection Product and Implementation Considerations for Sexual Health Clinical Research
Remote biospecimen collection (RBSC), such as home-based HIV testing and self-collection of dried blood spots (DBS) to assess adherence to antiretroviral drug regimens, has become an important tool to support clinical research because it can facilitate participant reach, lower participant burden, and reduce discomfort with attending research visits in clinic spaces. RBSC is common in sexual health clinical intervention trials to assess the impact…
PrEP as a “Hidden Message”
Within the context of this PrEP demonstration project, partner dynamics impacted PrEP adherence for HIV-negative cisgender women in serodiscordant relationships. We urge further investigation of relationship dynamics and PrEP adherence and persistence specifically among US-based cisgender women
Experiences around testing and linkage to HIV care among gay, bisexual and other men who have sex with men
Although the Kenyan Ministry of Health recognizes key populations in addressing the country's HIV epidemic, gay, bisexual, and other men who have sex with men (GBMSM) face challenges in HIV testing, linkage, and retention in care. This study aimed to inform the development of context-specific interventions to improve GBMSM's initiation in HIV care in Kenya. Drawing on in-depth semi-structured interview data from the Patient-Centered Care Project …
Assessing the Implementation Fidelity of a Patient-Centered, Combination Adherence Strategy to Support HIV Antiretroviral Therapy and Pre-Exposure Prophylaxis Adherence During Pregnancy and Breastfeed…
The Simplest Way to Go”
Long-acting injectable PrEP was approved for use in the US in 2021 but roll out has been slow, with few studies exploring uptake among cisgender women who inject drugs (WWID). We purposively recruited 25 WWID within 30-days of receiving a PrEP prescription from a low-barrier clinic co-located with a syringe services program to complete semi-structured interviews about PrEP product choice. We used an intersectional lens to compare decision-making …
Electronic Dose Monitoring Feedback (EMF) with Youth Living with HIV
Electronic dose monitoring with feedback (EMF) offers an opportunity to visualize daily dosing behaviors that can otherwise be difficult to appreciate. Visual displays, including early, on-time, late, or missed doses over time, can foster insights around patterns of dosing. Reactions to seeing these patterns among youth with HIV (YWH) who struggle with adherence are important to consider with EMF. YWH (ages 14-25) participating in the ATN152 TERA…
Acceptability, Feasibility, and Safety of the Shauriana Intervention for Young Kenyan Gay, Bisexual, and Other Men who Have Sex with Men, and Exploration of Potential Impact on Sexual Health Outcomes
In rights-constrained settings with pervasive stigma, a holistic approach to HIV prevention is needed to ensure knowledge and use of different HIV prevention tools and promote both sexual and mental health. In close collaboration with GBMSM community leaders in Kisumu, we developed a theory-based, culturally-tailored HIV prevention intervention that integrates sexual health and mental health support for young Kenyan GBMSM. We conducted a randomiz…
Emotion regulation as a potential moderator of the association between HIV stigma and nonadherence to antiretroviral therapy among youth living with HIV
INTRODUCTION: Human immunodeficiency virus (HIV)-related stigma affects adherence to antiretroviral therapy (ART) for youth living with HIV. Emotion regulation strategies such as cognitive reappraisal (reinterpreting adversity to mitigate emotional impact) and expressive suppression (inhibiting emotion-expressive behavior activated by adversity) may moderate the HIV stigma-ART adherence relationship in this group. METHODS: Using baseline data fro…
Incarceration history and opioid use among adults living with HIV and chronic pain
Motivational interviewing experiences from a community health worker-led HIV prevention and care intervention in rural Uganda
Motivational Interviewing (MI) and Community Health Workers (CHWs) are increasingly utilized in global settings to improve HIV outcomes, yet research exploring implementation strategies using MI and CHWs is lacking. We examined the experiences of CHWs and their clients in a counseling intervention which used MI-informed counseling to increase engagement in HIV prevention and treatment. This study was nested within the mLAKE cluster-randomized tri…
The impact of intimate partner violence on PrEP adherence among U.S. Cisgender women at risk for HIV
NCT02584140 (ClinicalTrials.gov), registered 15/10/2015
Pharmacologic Drug Detection and Self-Reported Adherence in the HPTN069/ACTG5305 Phase II PrEP Trial
Adherence drives efficacy in PrEP clinical trials. We compared drug concentrations and self-reported adherence in HPTN069/ACTG5305, a double-blinded, randomized trial of the safety and tolerability of candidate PrEP regimens that included maraviroc (MVC), tenofovir (TDF), and emtricitabine (FTC). Plasma drug concentrations and self-reported adherence by computer-assisted self-interview (CASI) were assessed at study weeks 24 and 48. Descriptive st…
Syndemic Psychosocial Conditions among Youth Living with HIV
Drug use, mental distress, and other psychosocial factors threaten HIV care for youth living with HIV (YLWH). We aimed to identify syndemic psychosocial patterns among YLWH and examine how such patterns shape HIV outcomes. Using baseline data from 208 YLWH enrolled in an HIV treatment adherence intervention, we performed latent class analysis on dichotomized responses to 9 psychosocial indicators (enacted HIV stigma; clinical depression and anxie…
Proximal and distal minority stressors and mental health among young gay and bisexual men and other men who have sex with men (GBMSM) in Kisumu, Kenya
Young gay and bisexual men and other men who have sex with men (GBMSM) in Kenya experience pervasive intersectional stigma and discrimination, contributing to elevated levels of negative mental health symptoms. Grounded in the Minority Stress Model, this paper explores associations of proximal and distal minority stressors with three types of negative mental health outcomes among young HIV‐negative GBMSM ( n = 63) between the ages of 19–34 who pa…
Virtual voices
Antiretroviral therapy (ART) adherence is suboptimal among gay, bisexual, and other men who have sex with men (GBMSM). Online interventions that incorporate social support represent new opportunities to improve adherence. This study focused on how social support was provided and sought within a technology-based ART adherence intervention. We coded and analyzed 1,751 messages. Within the social support messages, half of the time participants sough…
Barriers to linkage and retention in HIV care still persist among adolescent girls and young women in western Kenya
Adolescent girls and young women (AGYW) in sub-Saharan Africa experience delayed linkage to and poor retention in HIV care. Identifying and addressing specific barriers in HIV care programming is important to achieving the upgraded UNAIDS 95-95-95 targets and epidemic control. We examined these challenges among 103 HIV-positive AGYW in and out of HIV care in communities around Lake Victoria in western Kenya as part of a larger qualitative study t…
Acceptability of a Combination Adherence Strategy to Support HIV Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence During Pregnancy and Breastfeeding in Malawi
Missed Opportunities When We Focus only on Risk
Influence of Participant Perceptions of Adherence-Related Interactions with Study/Study Team on Drug Levels
Adherence to HIV pre-exposure prophylaxis (PrEP) study drug is critical for safety, tolerability, and efficacy trials, and may be affected by how adherence is communicated by the study staff to trial participants. Increasingly, clinical trials investigating PrEP are creating and implementing 'participant-centered' approaches that discuss potential non-adherence neutrally (without negative judgement) and support efforts to adhere versus insisting …
“When you talk it out … you will feel like the burden has somehow gone down, you will feel light”
Gay and bisexual men and other men who have sex with men (GBMSM) experience many sexual orientation-related stressors that negatively influence physical and mental health, making it imperative to understand their experiences of resilience-promoting resources such as social support. We utilized qualitative and participatory methodologies to examine sources of social support and types of social support received by GBMSM in Western Kenya through in-…
Challenges with PrEP Uptake and Adherence Among Gay, Bisexual, and Other Men Who Have Sex with Men in Kisumu, Kenya
Data on challenges with pre-exposure prophylaxis (PrEP) uptake and adherence among Kenyan gay, bisexual, and other men who have sex with men (GBMSM) are limited. In this mixed-methods sequential explanatory design study, our quantitative phase followed 157 at-risk, HIV-negative GBMSM who accepted PrEP and enrolled in a cohort with 12-month follow-up. Stored dried blood spots collected at two intervals were batch tested for tenofovir diphosphate (…
Randomized Controlled Trial of a Remote Coaching mHealth Adherence Intervention in Youth Living with HIV
Stigmatizing Policies Interact with Mental Health and Sexual Behaviours to Structurally Induce HIV Diagnoses Among European Men Who Have Sex with Men
Structural stigma shapes men who have sex with men's (MSM's) mental health and sexual behaviours. The aim of this study was to examine how stigmatizing policies interact with downstream anxiety/depression and sexual behaviours to structurally pattern HIV disparities among European MSM. We conducted a secondary data analysis of the European Men-who-have-sex-with-men Internet Survey (EMIS) from 2017. We included a total of 98,600 participants livin…
Sexual behavior and medication adherence in men who have sex with men participating in a pre-exposure prophylaxis study of combinations of Maraviroc, Tenofovir Disoproxil Fumarate and/or Emtricitabine…
Point-of-Care Test for Assessing Tenofovir Adherence
A situated-Information Motivation Behavioral Skills Model of Care Initiation and Maintenance (sIMB-CIM)
A sizable portion of adults living with chronic medical conditions (CMCs) delay initiation of care or maintain it inconsistently, which has tremendous personal and public costs. However, few explanatory models with high yield for intervention development and implementation have been proposed to date that would help to characterize and support care use for CMCs. A situated Information, Motivation, Behavioral Skills model of Care Initiation and Mai…
Barriers to Male Involvement in Antenatal Care in Rural Mozambique
Low rates of antenatal care (ANC) service uptake limit the potential impact of mother-to-child HIV-prevention strategies. Zambézia province, Mozambique, has one of the lowest proportions of ANC uptake among pregnant women in the country, despite the availability of free services. We sought to identify factors influencing ANC service uptake (including HIV counseling and testing) through qualitative methods. In addition, we encouraged discussion ab…
An Information-Motivation-Behavioral Skills Analysis of Diet and Exercise Behavior in Puerto Ricans with Diabetes
Frameworks are needed to inform diabetes self-care programs for diverse populations. We tested the Information-Motivation-Behavioral Skills (IMB) model in a sample of Puerto Ricans with Type 2 diabetes ( N = 118). Structural equation models evaluated model fit and interrelations between IMB constructs. For diet behavior, information and motivation related to behavioral skills ( r = 0.19, p < .05 and r = 0.39, p < .01, respectively); behavioral sk…
An Exploration of Pre-exposure Prophylaxis (PrEP) Initiation Among Women Who Inject Drugs
Percent Total Attrition
Health behavior interventions delivered at point of service include those that yoke an intervention protocol with existing systems of care (e.g., clinical care, social work, or case management). Though beneficial in a number of ways, such “hosted” intervention studies may be unable to retain participants that specifically discontinue their use of the hosting service. In light of recent practices that use percent total attrition as indicative of m…
Standard of care
Although there has long been demand for programs and procedures that support or enhance adherence to antiretroviral therapy (ART) among HIV+ patients, there is scant evidence about the extent to which medical clinics have been able to incorporate adherence interventions into their standard care. A survey of clinical care settings in New York and Connecticut indicated that the current standard of care is to provide only minimal levels of adherence…
An empirical test of the Information, Motivation and Behavioral Skills model of antiretroviral therapy adherence
Nearly perfect adherence to demanding antiretroviral therapy (ART) is now recognized as essential for HIV-positive patients to realize its life sustaining benefits. Despite the dire consequences of non-adherence, a large number of patients do not follow their ART regimen. While many factors influence adherence, the literature is dominated by studies on only one or a small set of them. Multivariate, theory-based models of adherence behavior are of…
Efficacy of Antiretroviral Therapy Adherence Interventions
OBJECTIVE: To conduct a quantitative review of published trials of antiretroviral therapy (ART) adherence interventions. DESIGN: A research synthesis of published ART adherence intervention outcome studies. SAMPLE: ART adherence intervention outcome studies meeting inclusion criteria published between 1996 and December 2004 (k=24). MAIN OUTCOME MEASURE: Effect sizes (ESs [d]) were calculated for each study outcome, producing 25 immediate postinte…
An information-motivation-behavioral skills model of adherence to antiretroviral therapy.
HIV-positive persons who do not maintain consistently high levels of adherence to often complex and toxic highly active antiretroviral therapy (HAART) regimens may experience therapeutic failure and deterioration of health status and may develop multidrug-resistant HIV that can be transmitted to uninfected others. The current analysis conceptualizes social and psychological determinants of adherence to HAART among HIV-positive individuals. The au…
Reasons for ART non-adherence in the Deep South
HIV prevalence in the American Deep South has reached crisis proportions and greater numbers of patients are enrolling in clinical care and beginning antiretroviral therapy (ART). In order to gain maximum benefit from ART, patients must sustain high levels of adherence to demanding regimens over extended periods of time. Many patients are unable to maintain high rates of adherence and may need assistance to do so, which may be based upon an under…
The Information–Motivation–Behavioral Skills Model of ART Adherence in a Deep South HIV+ Clinic Sample
Attitudes toward needle-sharing and HIV transmission risk behavior among HIV+ injection drug users in clinical care
Risky behavior related to injection drug use accounts for a considerable proportion of incident HIV infection in the United States. Large numbers of injection drug users (IDUs) currently receive antiretroviral therapy in clinical settings and are accessible for risk-reduction interventions to reduce transmission of drug-resistant HIV and spread of HIV to uninfected others. The current study examined attitudes toward needle- or equipment-sharing a…
The Relationship-Oriented Information-Motivation-Behavioral Skills Model
An Agenda for Advancing the Science of Implementation of Evidence-Based HIV Prevention Interventions
Percent Total Attrition
Health behavior interventions delivered at point of service include those that yoke an intervention protocol with existing systems of care (e.g., clinical care, social work, or case management). Though beneficial in a number of ways, such “hosted” intervention studies may be unable to retain participants that specifically discontinue their use of the hosting service. In light of recent practices that use percent total attrition as indicative of m…
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
BACKGROUND: Antiretroviral chemoprophylaxis before exposure is a promising approach for the prevention of human immunodeficiency virus (HIV) acquisition. METHODS: We randomly assigned 2499 HIV-seronegative men or transgender women who have sex with men to receive a combination of two oral antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate (FTC-TDF), or placebo once daily. All subjects received HIV testing, risk-reduction counse…
Information–motivation–behavioral skills barriers associated with intentional versus unintentional ARV non-adherence behavior among HIV+ patients in clinical care
Since the arrival of antiretroviral (ARV) therapy, HIV has become better characterized as a chronic disease rather than a terminal illness, depending in part on one's ability to maintain relatively high levels of adherence. Despite research concerning barriers and facilitators of ARV adherence behavior, relatively little is known about specific challenges faced by HIV-positive persons who report "taking a break" from their ARV medications. The pr…
An Information-Motivation-Behavioral Skills Analysis of Diet and Exercise Behavior in Puerto Ricans with Diabetes
Frameworks are needed to inform diabetes self-care programs for diverse populations. We tested the Information-Motivation-Behavioral Skills (IMB) model in a sample of Puerto Ricans with Type 2 diabetes ( N = 118). Structural equation models evaluated model fit and interrelations between IMB constructs. For diet behavior, information and motivation related to behavioral skills ( r = 0.19, p < .05 and r = 0.39, p < .01, respectively); behavioral sk…
Computer-Based Intervention in HIV Clinical Care Setting Improves Antiretroviral Adherence
Prevention Needs of HIV-Positive Men and Women Awaiting Release from Prison
A situated-Information Motivation Behavioral Skills Model of Care Initiation and Maintenance (sIMB-CIM)
A sizable portion of adults living with chronic medical conditions (CMCs) delay initiation of care or maintain it inconsistently, which has tremendous personal and public costs. However, few explanatory models with high yield for intervention development and implementation have been proposed to date that would help to characterize and support care use for CMCs. A situated Information, Motivation, Behavioral Skills model of Care Initiation and Mai…
Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV
DESCRIPTION: After HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). Adherence to ART is among the key determinants of successful HIV treatment outcome and is essential to minimize the emergence of drug resistance. The International Association of Physicians in AIDS Care convened a panel to develop evidence-based recommendations to optimize entry …
Antiretroviral therapy (ART) adherence and correlates to nonadherence among people on ART in Estonia
There are little data on antiretroviral therapy (ART) adherence among patients in Eastern Europe, despite the high incidence of HIV infection and the growing number of HIV-infected individuals who are being prescribed ART. The aim of this study was to measure rates of adherence to ART and factors associated with nonadherence among patients receiving care at an outpatient HIV clinic in Estonia. The study was based on cross-sectional data from a co…
Technology Use and Reasons to Participate in Social Networking Health Websites among People Living with HIV in the US
Supporting Study Product Use and Accuracy in Self-Report in the iPrEx Study
The State of Engagement in HIV Care in the United States
The National HIV/AIDS Strategy and the promise of treatment as prevention have garnered considerable attention from the policy, practice, and scientific communities, with the treatment cascade becoming the sentinel image illustrating the domestic human immunodeficiency virus (HIV) epidemic. The cascade depicts prevalence estimates for sequential steps from HIV diagnosis through viral suppression, the most striking of which is that >50% of persons…
Facilitators and barriers to medication adherence in an HIV prevention study among men who have sex with men in the iPrEx study in Chiang Mai, Thailand
In 2008, the Pre-exposure Prophylaxis Initiative (iPrEx) study expanded to include men who have sex with men (MSM) in Chiang Mai, Thailand. In full, 114 participants from Chiang Mai joined this international double-blinded trial of daily FTC-TDF (Truvada®) or placebo as a pre-exposure prophylaxis (PrEP) HIV prevention strategy. To better understand the characteristics of iPrEx participants specifically from this underserved population in Thailand…
Developing an adherence support intervention for patients on antiretroviral therapy in the context of the recent IDU-driven HIV/Aids epidemic in Estonia
There is limited data on and experience with interventions for antiretroviral therapy (ART) adherence support for patients on ART in Eastern Europe. We sought to identify a feasible adherence support intervention for delivery amongst HIV-positive adults receiving care in Estonia, where the HIV/AIDS epidemic has been mainly concentrated among injection drug users (IDUs). Our application of intervention mapping (IM) strategies used existing literat…
Information, motivation, and behavioral skills for early pre-ART engagement in HIV care among patients entering clinical care in KwaZulu-Natal, South Africa
Little is known regarding factors implicated in early engagement and retention in HIV care among individuals not yet eligible for antiretroviral therapy (pre-ART) in sub-Saharan Africa. Identifying such factors is critical for supporting retention in pre-ART clinical care to ensure timely ART initiation and optimize long-term health outcomes. We assessed patients' pre-ART HIV care-related information, motivation, and behavioral skills among newly…
HIV Stigma Mechanisms and Well-Being Among PLWH
HIV/AIDS Research and Interventions (90 obras) · Medicine (89 obras) · Family medicine (67 obras) · Psychology (56 obras) · HIV, Drug Use, Sexual Risk (45 obras) · Human immunodeficiency virus (HIV (41 obras) · Men who have sex with men (41 obras) · Public health (39 obras) · Nursing (38 obras) · Psychiatry (38 obras)