Myron S Cohen
Dados Biográficos
| ID | 302587 |
|---|---|
| NOME | Myron S Cohen |
| PRENOMES | Myron S |
| SOBRENOME | Cohen |
| ASSINATURA | COHEN M S |
| AFILIAÇÕES | University of North Carolina at Chapel Hill |
| ORCID | 0000-0001-5917-9664 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAÇÕES | 16 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1982 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 3 |
Geospatial and phylogenetic clustering of acute and recent HIV infections in Lilongwe, Malawi
HIV transmission during early HIV infection impedes efforts to end HIV as a public health threat, as diagnosis typically occurs after this period of elevated transmission risk. To guide diagnosis and prevention strategies, we evaluated the geospatial and phylogenetic clustering of acute and recent HIV infection in Lilongwe, Malawi. We identified people with acute (pre-seroconversion) HIV infection (AHI) and a random sample of people with post-acu…
Pregnancy rates and clinical outcomes among women living with HIV enrolled in HPTN 052
HPTN 052 was a multi-country clinical trial of cART for preventing heterosexual HIV-1 transmission. The study allowed participation of pregnant women and provided access to cART and contraceptives. We explored associations between pregnancy and clinical measures of HIV disease stage and progression. Of 869 women followed for 5.70 (SD = 1.62) years, 94.7% were married/cohabitating, 96% initiated cART, and 76.3% had >2 past pregnancies. Of 337 wome…
The Old Foe Syphilis Strikes Again
Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women
BACKGROUND: Safe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection. METHODS: We conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 …
HIV Linkage to Care and Retention in Care Rate Among MSM in Guangzhou, China
Antiretroviral Therapy for the Prevention of HIV-1 Transmission
BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for …
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection
Maximizing the impact of HIV prevention efforts
Despite efforts to increase access to HIV testing and counseling services, population coverage remains low. As a result, many people in sub-Saharan Africa do not know their own HIV status or the status of their sex partner(s). Recent evidence, however, indicates that as many as half of HIV-positive individuals in ongoing sexual relationships have an HIV-negative partner and that a significant proportion of new HIV infections in generalized epidem…
Expanding provider-initiated HIV testing at STI clinics in China
Despite expanding sexually transmitted epidemics in South China, the majority of patients presenting to sexually transmitted infection (STI) clinics are not routinely screened for HIV infection. Identifying barriers to offering HIV testing among STI care providers is an important public health priority. The aim of this study was to investigate the frequency of offering HIV testing among STI care providers in South China and reported physician bar…
Unsafe Sex and STI Prevalence Among HIV-Infected Adults in Guangzhou, China
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
BACKGROUND: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS: In nine countries, we enrolled 1763 couples in which one partner was HIV-1-positive and the other was HIV-1-negative; 54% of the subjects were from Africa, and 50% of infected partners were men. HIV-1-infected subjects with CD4 counts between 350 and 550 cells per cubic m…
Predicting Partner HIV Testing and Counseling Following a Partner Notification Intervention
Continued High Risk Sexual Behavior Following Diagnosis with Acute HIV Infection in South Africa and Malawi
Factors Associated with Utilization of a Free HIV VCT Clinic by Female Sex Workers in Jinan City, Northern China
Factors Related to Female Sex Workers’ Willingness to Utilize VCT Service
Prevalence of HIV Infection Among Young Adults in the United States
Objectives. We estimated HIV prevalence rates among young adults in the United States. Methods. We used survey data from the third wave of the National Longitudinal Study of Adolescent Health, a random sample of nearly 19000 young adults initiated in 1994–1995. Consenting respondents were screened for the presence of antibodies to HIV-1 in oral mucosal transudate specimens. We calculated prevalence rates, accounting for survey design, response ra…
Surplus men, sex work, and the spread of HIV in China
While 70% of HIV positive individuals live in sub-Saharan Africa, it is widely believed that the future of the epidemic depends on the magnitude of HIV spread in India and China, the world's most populous countries. China's 1.3 billion people are in the midst of significant social transformation, which will impact future sexual disease transmission. Soon approximately 8.5 million 'surplus men', unmarried and disproportionately poor and migrant, w…
Brief but Efficient
BACKGROUND: We examined whether viral dynamics in the genital tract during the natural history of acute human immunodeficiency virus type 1 (HIV-1) infection could explain efficient heterosexual transmission of HIV. METHODS: We measured HIV-1 concentration in blood and semen samples from patients with acute and long-term HIV-1 infection. We explored the effect of changes in viral dynamics in semen on the probability of transmission per coital act…
HIV/Aids Risk Among Brothel-Based Female Sex Workers in China
BACKGROUND: Sexual transmission of HIV in China is rapidly increasing, in part driven by commercial sex work. GOAL: This article examines variations in occupational control among one type of brothel-based prostitutes in China, and the relationship between the terms and content of this work and the risk of HIV/AIDS. Organizational factors are discussed as part of the current political, economic, and social context of sex work in China. STUDY: The …
Population-Based Study of Chlamydial Infection in China
CONTEXT: Sexually transmitted diseases are increasing rapidly in China. Surveillance data imperfectly indicate current prevalence and risk factors. OBJECTIVES: To estimate the prevalence of genital chlamydial and gonococcal infections and to describe patterns of infection by subgroup and behavioral patterns. DESIGN, SETTING, AND PARTICIPANTS: A national stratified probability sample of 3426 Chinese individuals (1738 women and 1688 men) aged 20 to…
Primary HIV infection--a public health opportunity
Primary human immunodeficiency virus (HIV) infection should be considered a key target for HIV prevention activities. Mathematical models suggest that the primary HIV infection interval makes a disproportionate contribution to the HIV epidemic, perhaps accounting for as many as half of the existing infections at any point in time. If this is true, primary infection presents a special window of opportunity within which to exert a maximum impact on…
The Chinese Hospital
Chinese Medical Modernization. Comparative Policy Continuities, 1930s-1980s
Heatlh care in the People's Republic of China
During a three-month period, all admissions to an infectious disease ward at a tertiary care hospital in the People's Republic of China were studied. The hospital's catchment area covered a population of almost eight million, 10 per cent urban and 90 per cent rural. Seventy-two per cent of the patients admitted to this facility were city dwellers with illnesses which were significantly less serious in degree than the illnesses encountered among p…
Medicine under socialism
Prevalence of HIV Infection Among Young Adults in the United States
Objectives. We estimated HIV prevalence rates among young adults in the United States. Methods. We used survey data from the third wave of the National Longitudinal Study of Adolescent Health, a random sample of nearly 19000 young adults initiated in 1994–1995. Consenting respondents were screened for the presence of antibodies to HIV-1 in oral mucosal transudate specimens. We calculated prevalence rates, accounting for survey design, response ra…
Heatlh care in the People's Republic of China
During a three-month period, all admissions to an infectious disease ward at a tertiary care hospital in the People's Republic of China were studied. The hospital's catchment area covered a population of almost eight million, 10 per cent urban and 90 per cent rural. Seventy-two per cent of the patients admitted to this facility were city dwellers with illnesses which were significantly less serious in degree than the illnesses encountered among p…
Medicine under socialism
Primary HIV infection--a public health opportunity
Primary human immunodeficiency virus (HIV) infection should be considered a key target for HIV prevention activities. Mathematical models suggest that the primary HIV infection interval makes a disproportionate contribution to the HIV epidemic, perhaps accounting for as many as half of the existing infections at any point in time. If this is true, primary infection presents a special window of opportunity within which to exert a maximum impact on…
Heatlh care in the People's Republic of China
During a three-month period, all admissions to an infectious disease ward at a tertiary care hospital in the People's Republic of China were studied. The hospital's catchment area covered a population of almost eight million, 10 per cent urban and 90 per cent rural. Seventy-two per cent of the patients admitted to this facility were city dwellers with illnesses which were significantly less serious in degree than the illnesses encountered among p…
Medicine under socialism
The Chinese Hospital
Chinese Medical Modernization. Comparative Policy Continuities, 1930s-1980s
Primary HIV infection--a public health opportunity
Primary human immunodeficiency virus (HIV) infection should be considered a key target for HIV prevention activities. Mathematical models suggest that the primary HIV infection interval makes a disproportionate contribution to the HIV epidemic, perhaps accounting for as many as half of the existing infections at any point in time. If this is true, primary infection presents a special window of opportunity within which to exert a maximum impact on…
Population-Based Study of Chlamydial Infection in China
CONTEXT: Sexually transmitted diseases are increasing rapidly in China. Surveillance data imperfectly indicate current prevalence and risk factors. OBJECTIVES: To estimate the prevalence of genital chlamydial and gonococcal infections and to describe patterns of infection by subgroup and behavioral patterns. DESIGN, SETTING, AND PARTICIPANTS: A national stratified probability sample of 3426 Chinese individuals (1738 women and 1688 men) aged 20 to…
Brief but Efficient
BACKGROUND: We examined whether viral dynamics in the genital tract during the natural history of acute human immunodeficiency virus type 1 (HIV-1) infection could explain efficient heterosexual transmission of HIV. METHODS: We measured HIV-1 concentration in blood and semen samples from patients with acute and long-term HIV-1 infection. We explored the effect of changes in viral dynamics in semen on the probability of transmission per coital act…
HIV/Aids Risk Among Brothel-Based Female Sex Workers in China
BACKGROUND: Sexual transmission of HIV in China is rapidly increasing, in part driven by commercial sex work. GOAL: This article examines variations in occupational control among one type of brothel-based prostitutes in China, and the relationship between the terms and content of this work and the risk of HIV/AIDS. Organizational factors are discussed as part of the current political, economic, and social context of sex work in China. STUDY: The …
Surplus men, sex work, and the spread of HIV in China
While 70% of HIV positive individuals live in sub-Saharan Africa, it is widely believed that the future of the epidemic depends on the magnitude of HIV spread in India and China, the world's most populous countries. China's 1.3 billion people are in the midst of significant social transformation, which will impact future sexual disease transmission. Soon approximately 8.5 million 'surplus men', unmarried and disproportionately poor and migrant, w…
Prevalence of HIV Infection Among Young Adults in the United States
Objectives. We estimated HIV prevalence rates among young adults in the United States. Methods. We used survey data from the third wave of the National Longitudinal Study of Adolescent Health, a random sample of nearly 19000 young adults initiated in 1994–1995. Consenting respondents were screened for the presence of antibodies to HIV-1 in oral mucosal transudate specimens. We calculated prevalence rates, accounting for survey design, response ra…
Factors Related to Female Sex Workers’ Willingness to Utilize VCT Service
Continued High Risk Sexual Behavior Following Diagnosis with Acute HIV Infection in South Africa and Malawi
Factors Associated with Utilization of a Free HIV VCT Clinic by Female Sex Workers in Jinan City, Northern China
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
BACKGROUND: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS: In nine countries, we enrolled 1763 couples in which one partner was HIV-1-positive and the other was HIV-1-negative; 54% of the subjects were from Africa, and 50% of infected partners were men. HIV-1-infected subjects with CD4 counts between 350 and 550 cells per cubic m…
Predicting Partner HIV Testing and Counseling Following a Partner Notification Intervention
Expanding provider-initiated HIV testing at STI clinics in China
Despite expanding sexually transmitted epidemics in South China, the majority of patients presenting to sexually transmitted infection (STI) clinics are not routinely screened for HIV infection. Identifying barriers to offering HIV testing among STI care providers is an important public health priority. The aim of this study was to investigate the frequency of offering HIV testing among STI care providers in South China and reported physician bar…
Unsafe Sex and STI Prevalence Among HIV-Infected Adults in Guangzhou, China
Maximizing the impact of HIV prevention efforts
Despite efforts to increase access to HIV testing and counseling services, population coverage remains low. As a result, many people in sub-Saharan Africa do not know their own HIV status or the status of their sex partner(s). Recent evidence, however, indicates that as many as half of HIV-positive individuals in ongoing sexual relationships have an HIV-negative partner and that a significant proportion of new HIV infections in generalized epidem…
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection
Antiretroviral Therapy for the Prevention of HIV-1 Transmission
BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for …
HIV Linkage to Care and Retention in Care Rate Among MSM in Guangzhou, China
Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women
BACKGROUND: Safe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection. METHODS: We conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 …
The Old Foe Syphilis Strikes Again
Pregnancy rates and clinical outcomes among women living with HIV enrolled in HPTN 052
HPTN 052 was a multi-country clinical trial of cART for preventing heterosexual HIV-1 transmission. The study allowed participation of pregnant women and provided access to cART and contraceptives. We explored associations between pregnancy and clinical measures of HIV disease stage and progression. Of 869 women followed for 5.70 (SD = 1.62) years, 94.7% were married/cohabitating, 96% initiated cART, and 76.3% had >2 past pregnancies. Of 337 wome…
Geospatial and phylogenetic clustering of acute and recent HIV infections in Lilongwe, Malawi
HIV transmission during early HIV infection impedes efforts to end HIV as a public health threat, as diagnosis typically occurs after this period of elevated transmission risk. To guide diagnosis and prevention strategies, we evaluated the geospatial and phylogenetic clustering of acute and recent HIV infection in Lilongwe, Malawi. We identified people with acute (pre-seroconversion) HIV infection (AHI) and a random sample of people with post-acu…
Medicine (20 obras) · HIV/AIDS Research and Interventions (16 obras) · Environmental health (11 obras) · Demography (10 obras) · HIV, Drug Use, Sexual Risk (10 obras) · Family medicine (9 obras) · Human immunodeficiency virus (HIV) (9 obras) · Adolescent Sexual and Reproductive Health (8 obras) · China (8 obras) · Internal Medicine (8 obras)