Darrell H S Tan
Dados Biográficos
| ID | 307340 |
|---|---|
| NOME | Darrell H S Tan |
| PRENOMES | Darrell H S |
| SOBRENOME | Tan |
| ASSINATURA | TAN D H S |
| AFILIAÇÕES | St. Michael's Hospital |
| ORCID | 0000-0002-3069-2875 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 31 |
| TOTAL DE CITAÇÕES | 12 |
| TOTAL COMO AUTOR | 31 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2003 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 2 |
Disentangling Between- and Within-Person Effects of HIV PrEP and Treatment Attitudes on Condom Use and Bacterial STIs Among Sexual Minority Men
Substance Use and Incidence of Psychosis Diagnoses Among Gay, Bisexual, and Other Men Who Have Sex with Men Compared with Males from the General Population
BACKGROUND: Gay, bisexual, and other men who have sex with men (GBM) report higher use of psychoactive substances, which may contribute to many adverse outcomes. METHOD: We examined the incidence of psychosis and associated substance use among GBM compared with males from the general male population. We analyzed data from 798 sexually active GBM from two cohort studies based in Vancouver, Canada, linking their survey data to administrative health…
Viral suppression by residency status among men living with HIV in the context of the expanded ART policy in Shanghai, China
Access to China’s national free antiretroviral therapy (ART) program was historically restricted to the home province or province of birth (“Hukou”). During the COVID-19 pandemic, Shanghai facilitated access to free ART and supportive services for all Shanghai residents regardless of residency status. Our aim was to study differences in viral suppression according to residency status in Shanghai, China. We conducted a cross-sectional survey with …
Migration status, discrimination, and recent sexually transmitted infection testing among South Asian gay, bisexual, and other queer men living in Canada
Community-Led Responses to Mpox Among Gay, Bisexual, and Queer Men in Canada
Since 2022, a global mpox outbreak in non-endemic countries, including Canada, has spread rapidly, mainly affecting gay, bisexual, and queer men (GBQM). With mpox primarily transmitted through sexual and close physical contact, concerns emerged over the replication of early responses to HIV/AIDS, which was initially labeled as a “gay disease,” perpetuating ongoing negative stereotypes and discrimination against GBQM. To prevent potential social a…
Disparities in healthcare, STI testing, and PrEP access among newcomer sexual minority men in Canada's three largest urban centers
Gay, bisexual, and other men who have sex with men (GBM) are more likely to be diagnosed with HIV and other sexually transmitted infections (STIs) compared with the general population. Although newcomers generally experience a health advantage in Canada compared with non‐immigrants and more established immigrants (i.e., healthy immigrant effect), they also experience disparities in access to healthcare services. These disparities, in turn, may le…
From stigmatized status to responsibilized health behavior
For many gay, bisexual, and queer men (GBQM), using HIV pre-exposure prophylaxis (PrEP) has been extremely stigmatizing. Our objective was to trace changes in PrEP stigma within the accounts of GBQM in Canada, many with experience using this highly effective form of biomedical HIV prevention. We conducted annual longitudinal qualitative interviews with 46 HIV-negative GBQM living in Ontario or British Columbia, Canada. A total of 128 in-depth int…
Characteristics of individuals who received a complete, 2-dose mpox vaccine regimen as part of the public health response to the mpox epidemic in Ontario, Canada
In May 2022, an outbreak of mpox emerged in Canada. In June 2022, the province of Ontario began offering first doses of a 2-dose regimen of Modified Vaccinia Ankara–Bavaria Nordic (MVA-BN) to those at high risk of exposure. Second doses became available in September 2022. To help increase dose 2 access and uptake, we sought to understand how individuals who received 2 doses differed from those who received only 1 dose. We conducted a cross-sectio…
Impact of “absolute” versus “relative” HIV risk communication on pre-exposure prophylaxis interest in Canada
The way human immunodeficiency virus (HIV) acquisition risk is communicated can shape individuals’ perceptions and their interest in using pre-exposure prophylaxis (PrEP). This study examined two risk communication strategies among non-PrEP-using gay, bisexual, and other men who have sex with men (GBM) in Canada. In 2022, adult GBMs in Ontario and British Columbia completed an online survey and were randomly assigned to receive HIV risk messages …
Racial disparities in HIV pre-exposure prophylaxis (PrEP) awareness and uptake among white, Black, and Indigenous men in Canada
Community-based and public health interventions are immediately needed to increase PrEP awareness, access, and uptake for Black and Indigenous communities in Canada
Post-arrival HIV acquisition patterns
Different classes of crystal methamphetamine use are associated with psychological and sexually transmitted infection outcomes among gay, bisexual, and other men who have sex with men
Navigating patterns of oral PrEP use
The Canadian HIV pre-exposure prophylaxis (PrEP) guidelines recommend both daily and on-demand dosing for gay, bisexual, and queer men (GBQM), meeting additional risk criteria. However, limited research explored how GBQM implement pausing, on-demand, discontinuation, and resumption of PrEP, including the contextual factors affecting decision-making. Using a relationally situated implementation science framework, we examined how GBQM tailor PrEP u…
Dynamics of intersectional and multilevel Covid-19 stigma across time
To do so in a patient-centred way is not particularly lucrative
It's not as good as the face-to-face contact
The COVID-19 pandemic led to the widespread adoption of virtual care-the use of communication technologies to receive health care at home. We explored the differential impacts of the rapid transition to virtual care during the COVID-19 pandemic on health-care access and delivery for gay, bisexual and queer men (GBQM), a population that disproportionately experiences sexual and mental health disparities in Canada. Adopting a sociomaterial theoreti…
Disclosure of HIV-serodiscordant relationships and association with viral suppression
BACKGROUND: Little is known about the effects of disclosure of HIV-serodiscordant relationships on clinical outcomes. We aimed to evaluate the effect of relationship disclosure on HIV viral suppression, and hypothesized that disclosure by HIV-positive and HIV-negative partners would be associated with viral suppression in the HIV-positive partner. METHODS: We conducted a Canadian national online and telephone-administered survey of HIV-positive a…
Disjuncture between self-perceived and clinically assessed risk of HIV among gay, bisexual, and other men who have sex with men in Ontario and British Columbia, Canada
There is a disjuncture between self-perceived and clinically assessed risk of HIV. Some GBM may underestimate their HIV risk and clinical criteria may overestimate risk. Bridging these gaps requires efforts to increase HIV risk awareness in the community, and refinement of clinical assessments based on individualized discussions between the provider and the user
It’s different for heterosexuals”
Critical scholarship has illustrated how COVID-19 public health policies can enact racism, classism, and cis-heteronormativity, perpetuating harms among vulnerable communities. We sought to examine the accounts of gay, bisexual, and queer men (GBQM) in Canada on how normative ideologies played out in COVID-19 directives and what impacts these orders had on their lives. Two rounds of semi-structured interviews with GBQM in Montreal (n = 30), Toron…
I did not have sex outside of our bubble’
In efforts to prevent the spread of COVID-19, jurisdictions across the globe, including Canada, enacted containment measures that affected intimacy and sexual relations. This article examines how public health measures during COVID-19 impacted the sexual practices of sexual minority men- gay, bisexual, queer and other men who have sex with men-and how they adopted and modified guidelines to prevent the transmission of COVID-19, HIV and other sexu…
Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022
BACKGROUND: Before April 2022, monkeypox virus infection in humans was seldom reported outside African regions where it is endemic. Currently, cases are occurring worldwide. Transmission, risk factors, clinical presentation, and outcomes of infection are poorly defined. METHODS: We formed an international collaborative group of clinicians who contributed to an international case series to describe the presentation, clinical course, and outcomes o…
A national recruitment strategy for HIV-serodiscordant partners living in Canada for the Positive Plus One study
Our findings provide important new information on and support the use of a multi-pronged approach to recruit HIV-positive and HIV-negative individuals involved in HIV-serodiscordant relationships in Canada. More creative strategies are needed to help index partners recruit their partner in relationships with lower satisfaction and shorter duration and further minimize the risk of "happy couple" bias
What other choices might I have made
The PrEP Cascade is a dominant framework for investigating barriers to HIV pre-exposure prophylaxis (PrEP), an HIV prevention tool. We interviewed 37 PrEP users and 8 non-PrEP users in Ontario and British Columbia, Canada, about their decision-making through the Cascade. Participants were HIV-negative gay, bisexual, and queer men (GBQM). The data were analyzed using thematic analysis. PrEP decision-making was based on pragmatic considerations (lo…
Public health morality, sex, and Covid-19
Experts have warned that COVID-19 control measures may amplify health inequities among gay, bisexual, queer, and other men who have sex with men (GBM). For HIV-negative GBM, concerns have been raised as to how COVID-19 will disrupt access to HIV pre-exposure prophylaxis (PrEP). Our study offers empirical findings on these issues, drawing on in-depth interviews conducted with 25 HIV-negative GBM living in Ontario, Canada during the first wave of t…
Prevalence of HIV and sexually transmitted and blood-borne infections, and related preventive and risk behaviours, among gay, bisexual and other men who have sex with men in Montreal, Toronto and Vanc…
The three largest cities of Canada differed in HIV prevalence, STBBI testing and PrEP use among GBM. Our findings also suggest the need for scale-up of both PrEP and STI testing among GBM in Canada
Trends in HIV pre-exposure prophylaxis uptake in Ontario, Canada, and impact of policy changes
PrEP use has risen in Ontario in association with favourable policy changes, but remains far below guideline recommendations
It's not as good as the face-to-face contact
The COVID-19 pandemic led to the widespread adoption of virtual care-the use of communication technologies to receive health care at home. We explored the differential impacts of the rapid transition to virtual care during the COVID-19 pandemic on health-care access and delivery for gay, bisexual and queer men (GBQM), a population that disproportionately experiences sexual and mental health disparities in Canada. Adopting a sociomaterial theoreti…
What other choices might I have made
The PrEP Cascade is a dominant framework for investigating barriers to HIV pre-exposure prophylaxis (PrEP), an HIV prevention tool. We interviewed 37 PrEP users and 8 non-PrEP users in Ontario and British Columbia, Canada, about their decision-making through the Cascade. Participants were HIV-negative gay, bisexual, and queer men (GBQM). The data were analyzed using thematic analysis. PrEP decision-making was based on pragmatic considerations (lo…
Prevalence of HIV and sexually transmitted and blood-borne infections, and related preventive and risk behaviours, among gay, bisexual and other men who have sex with men in Montreal, Toronto and Vanc…
The three largest cities of Canada differed in HIV prevalence, STBBI testing and PrEP use among GBM. Our findings also suggest the need for scale-up of both PrEP and STI testing among GBM in Canada
Trends in the awareness, acceptability, and usage of HIV pre-exposure prophylaxis among at-risk men who have sex with men in Toronto
To maximize its potential public health benefits, PrEP scale-up strategies must address self-perceived HIV risk and increase access to PrEP providers
Global plagues and the Global Fund
BACKGROUND: Although a grossly disproportionate burden of disease from HIV/AIDS, TB and malaria remains in the Global South, these infectious diseases have finally risen to the top of the international agenda in recent years. Ideal strategies for combating these diseases must balance the advantages and disadvantages of 'vertical' disease control programs and 'horizontal' capacity-building approaches. DISCUSSION: The Global Fund to Fight AIDS, Tub…
HIV testing during the Canadian immigration medical examination
HIV testing is mandatory for individuals wishing to immigrate to Canada. Since the Designated Medical Practitioners (DMPs) who perform these tests may have varying experience in HIV and time constraints in their clinical practices, there may be variability in the quality of pre- and posttest counseling provided. We surveyed DMPs regarding HIV testing, counseling, and immigration inadmissibility. A 16-item survey was mailed to all DMPs across Cana…
Self-Administered Screening for Syndemic Mental Health Problems Should be Routinely Implemented Among MSM PrEP Users
Although literature has repeatedly shown that populations of men who have sex with men have (MSM) higher rates of mental health issues, including depression and addiction, routine screening is not part of standard care. This case series explores the value of implementing routine screening in a population of MSM before initiating HIV pre-exposure prophylaxis. We found the use of self-administered questionnaires for depression and substance use pro…
High HIV risk and syndemic burden regardless of referral source among MSM screening for a PrEP demonstration project in Toronto, Canada
ClinicalTrials.gov NCT02149888 . Registered May 12th 2014
Trends in the awareness, acceptability, and usage of HIV pre-exposure prophylaxis among at-risk men who have sex with men in Toronto
To maximize its potential public health benefits, PrEP scale-up strategies must address self-perceived HIV risk and increase access to PrEP providers
Trends in HIV pre-exposure prophylaxis uptake in Ontario, Canada, and impact of policy changes
PrEP use has risen in Ontario in association with favourable policy changes, but remains far below guideline recommendations
Public health morality, sex, and Covid-19
Experts have warned that COVID-19 control measures may amplify health inequities among gay, bisexual, queer, and other men who have sex with men (GBM). For HIV-negative GBM, concerns have been raised as to how COVID-19 will disrupt access to HIV pre-exposure prophylaxis (PrEP). Our study offers empirical findings on these issues, drawing on in-depth interviews conducted with 25 HIV-negative GBM living in Ontario, Canada during the first wave of t…
Prevalence of HIV and sexually transmitted and blood-borne infections, and related preventive and risk behaviours, among gay, bisexual and other men who have sex with men in Montreal, Toronto and Vanc…
The three largest cities of Canada differed in HIV prevalence, STBBI testing and PrEP use among GBM. Our findings also suggest the need for scale-up of both PrEP and STI testing among GBM in Canada
Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022
BACKGROUND: Before April 2022, monkeypox virus infection in humans was seldom reported outside African regions where it is endemic. Currently, cases are occurring worldwide. Transmission, risk factors, clinical presentation, and outcomes of infection are poorly defined. METHODS: We formed an international collaborative group of clinicians who contributed to an international case series to describe the presentation, clinical course, and outcomes o…
A national recruitment strategy for HIV-serodiscordant partners living in Canada for the Positive Plus One study
Our findings provide important new information on and support the use of a multi-pronged approach to recruit HIV-positive and HIV-negative individuals involved in HIV-serodiscordant relationships in Canada. More creative strategies are needed to help index partners recruit their partner in relationships with lower satisfaction and shorter duration and further minimize the risk of "happy couple" bias
What other choices might I have made
The PrEP Cascade is a dominant framework for investigating barriers to HIV pre-exposure prophylaxis (PrEP), an HIV prevention tool. We interviewed 37 PrEP users and 8 non-PrEP users in Ontario and British Columbia, Canada, about their decision-making through the Cascade. Participants were HIV-negative gay, bisexual, and queer men (GBQM). The data were analyzed using thematic analysis. PrEP decision-making was based on pragmatic considerations (lo…
Disclosure of HIV-serodiscordant relationships and association with viral suppression
BACKGROUND: Little is known about the effects of disclosure of HIV-serodiscordant relationships on clinical outcomes. We aimed to evaluate the effect of relationship disclosure on HIV viral suppression, and hypothesized that disclosure by HIV-positive and HIV-negative partners would be associated with viral suppression in the HIV-positive partner. METHODS: We conducted a Canadian national online and telephone-administered survey of HIV-positive a…
Disjuncture between self-perceived and clinically assessed risk of HIV among gay, bisexual, and other men who have sex with men in Ontario and British Columbia, Canada
There is a disjuncture between self-perceived and clinically assessed risk of HIV. Some GBM may underestimate their HIV risk and clinical criteria may overestimate risk. Bridging these gaps requires efforts to increase HIV risk awareness in the community, and refinement of clinical assessments based on individualized discussions between the provider and the user
It’s different for heterosexuals”
Critical scholarship has illustrated how COVID-19 public health policies can enact racism, classism, and cis-heteronormativity, perpetuating harms among vulnerable communities. We sought to examine the accounts of gay, bisexual, and queer men (GBQM) in Canada on how normative ideologies played out in COVID-19 directives and what impacts these orders had on their lives. Two rounds of semi-structured interviews with GBQM in Montreal (n = 30), Toron…
I did not have sex outside of our bubble’
In efforts to prevent the spread of COVID-19, jurisdictions across the globe, including Canada, enacted containment measures that affected intimacy and sexual relations. This article examines how public health measures during COVID-19 impacted the sexual practices of sexual minority men- gay, bisexual, queer and other men who have sex with men-and how they adopted and modified guidelines to prevent the transmission of COVID-19, HIV and other sexu…
Different classes of crystal methamphetamine use are associated with psychological and sexually transmitted infection outcomes among gay, bisexual, and other men who have sex with men
Navigating patterns of oral PrEP use
The Canadian HIV pre-exposure prophylaxis (PrEP) guidelines recommend both daily and on-demand dosing for gay, bisexual, and queer men (GBQM), meeting additional risk criteria. However, limited research explored how GBQM implement pausing, on-demand, discontinuation, and resumption of PrEP, including the contextual factors affecting decision-making. Using a relationally situated implementation science framework, we examined how GBQM tailor PrEP u…
Dynamics of intersectional and multilevel Covid-19 stigma across time
To do so in a patient-centred way is not particularly lucrative
It's not as good as the face-to-face contact
The COVID-19 pandemic led to the widespread adoption of virtual care-the use of communication technologies to receive health care at home. We explored the differential impacts of the rapid transition to virtual care during the COVID-19 pandemic on health-care access and delivery for gay, bisexual and queer men (GBQM), a population that disproportionately experiences sexual and mental health disparities in Canada. Adopting a sociomaterial theoreti…
Disparities in healthcare, STI testing, and PrEP access among newcomer sexual minority men in Canada's three largest urban centers
Gay, bisexual, and other men who have sex with men (GBM) are more likely to be diagnosed with HIV and other sexually transmitted infections (STIs) compared with the general population. Although newcomers generally experience a health advantage in Canada compared with non‐immigrants and more established immigrants (i.e., healthy immigrant effect), they also experience disparities in access to healthcare services. These disparities, in turn, may le…
From stigmatized status to responsibilized health behavior
For many gay, bisexual, and queer men (GBQM), using HIV pre-exposure prophylaxis (PrEP) has been extremely stigmatizing. Our objective was to trace changes in PrEP stigma within the accounts of GBQM in Canada, many with experience using this highly effective form of biomedical HIV prevention. We conducted annual longitudinal qualitative interviews with 46 HIV-negative GBQM living in Ontario or British Columbia, Canada. A total of 128 in-depth int…
Characteristics of individuals who received a complete, 2-dose mpox vaccine regimen as part of the public health response to the mpox epidemic in Ontario, Canada
In May 2022, an outbreak of mpox emerged in Canada. In June 2022, the province of Ontario began offering first doses of a 2-dose regimen of Modified Vaccinia Ankara–Bavaria Nordic (MVA-BN) to those at high risk of exposure. Second doses became available in September 2022. To help increase dose 2 access and uptake, we sought to understand how individuals who received 2 doses differed from those who received only 1 dose. We conducted a cross-sectio…
Impact of “absolute” versus “relative” HIV risk communication on pre-exposure prophylaxis interest in Canada
The way human immunodeficiency virus (HIV) acquisition risk is communicated can shape individuals’ perceptions and their interest in using pre-exposure prophylaxis (PrEP). This study examined two risk communication strategies among non-PrEP-using gay, bisexual, and other men who have sex with men (GBM) in Canada. In 2022, adult GBMs in Ontario and British Columbia completed an online survey and were randomly assigned to receive HIV risk messages …
Racial disparities in HIV pre-exposure prophylaxis (PrEP) awareness and uptake among white, Black, and Indigenous men in Canada
Community-based and public health interventions are immediately needed to increase PrEP awareness, access, and uptake for Black and Indigenous communities in Canada
HIV/AIDS Research and Interventions (24 obras) · Medicine (21 obras) · Men who have sex with men (15 obras) · HIV, Drug Use, Sexual Risk (14 obras) · Human immunodeficiency virus (HIV (13 obras) · Family medicine (12 obras) · Psychology (12 obras) · Public health (11 obras) · Sex work and related issues (11 obras) · Political science (9 obras)