Yoav Ben-Shlomo
Dados Biográficos
| ID | 327786 |
|---|---|
| NOME | Yoav Ben-Shlomo |
| PRENOMES | Yoav |
| SOBRENOME | Ben-Shlomo |
| ASSINATURA | BEN-SHLOMO Y |
| AFILIAÇÕES | University of Bristol |
| ORCID | 0000-0001-6648-3007 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 56 |
| TOTAL DE CITAÇÕES | 171 |
| TOTAL COMO AUTOR | 56 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1991 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2023 |
| ÍNDICE H | 7 |
Treatment Decision-Making in Myocardial Infarction for People With Advanced Kidney Disease
Background: People with chronic kidney disease (CKD) have significantly higher morbidity and mortality following myocardial infarction (MI) than the general population. Despite this, they are less likely to receive invasive management and guideline-directed medications than those without kidney disease. It is unclear why this treatment variation exists and whether or not it reflects equal and appropriate access to care for the high-risk CKD popul…
Expectations of a new opt‐out system of consent for deceased organ donation in England
INTRODUCTION: In 2020 England moved to an opt-out deceased donation law. We aimed to investigate the views of a mixed stakeholder group comprising people with kidney disease, family members and healthcare practitioners towards the change in legislation. We investigated the expected impacts of the new legislation on deceased-donor and living-donor transplantation, and views on media campaigns regarding the law change. METHODS: We undertook in-dept…
World Health Organization cardiovascular disease risk charts
BACKGROUND: To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. Here, we report the derivation, validation, and illustration of the revised WHO cardiovascular disease risk prediction charts that have been adapted to the circumstances of 21 global regions. METHODS: In this model revision initiative, we derived…
Social determinants of multimorbidity and multiple functional limitations among the ageing population of England, 2002–2015
This study explores longitudinal relationships between material, psycho-social and behavioural social determinants of health and multimorbidity of people aged 50 years or older in England. We used data from the English Longitudinal Study of Ageing collected biannually between 2002 and 2015. Apart from the basic measure of multimorbidity (two or more diseases within a person) we constructed two distinct measures of health in order to take into acc…
Age-related inequalities in colon cancer treatment persist over time
BACKGROUND: Older people experience poorer outcomes from colon cancer. We examined if treatment for colon cancer was related to age and if inequalities changed over time. METHODS: Data from the UK population-based Northern and Yorkshire Cancer Registry on 31 910 incident colon cancers (ICD10 C18) diagnosed between 1999-2010 were obtained. Likelihood of receipt of: (1) cancer-directed surgery, (2) chemotherapy in surgical patients, (3) chemotherap…
Response to
No abstract available
Frailty in older-age European migrants
Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men
BACKGROUND: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. METHODS: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathe…
Migration and social determinants of mental health
Genetic evidence of assortative mating in humans
Prevalence and severity of depressive symptoms in relation to rural-to-urban migration in India
There was no evidence for an increased prevalence of mild to severe depressive symptoms among rural-urban migrants compared to rural or urban residents
Better the donor you know? A qualitative study of renal patients' views on 'altruistic' live-donor kidney transplantation
Life Course Epidemiology
Development and evaluation of the Andhra Pradesh Children and Parent Study Physical Activity Questionnaire (Apcaps-PAQ)
The APCAPS-PAQ validity is comparable to other physical activity questionnaires. This tool is able to assess sedentary behavior, moderate/vigorous activity and physical activity energy expenditure on a group level with reasonable validity. This new questionnaire may be used for ranking individuals according to their sedentary time and physical activity in southern India
Associations between diet, physical activity and body fat distribution
In this Indian population, there was an inverse association between PA and body fat. Associations between body fat and dietary variables differed between the younger APCAPS population and older IMS population. Further longitudinal research is needed to elucidate causality and directions of these associations across the life course
Dietary patterns in India and their association with obesity and central obesity
Objective Obesity is a growing problem in India, the dietary determinants of which have been studied using an ‘individual food/nutrient’ approach. Examining dietary patterns may provide more coherent findings, but few studies in developing countries have adopted this approach. The present study aimed to identify dietary patterns in an Indian population and assess their relationship with anthropometric risk factors. Design FFQ data from the cross-…
Socioeconomic conditions across life related to multiple measures of the endocrine system in older adults
Lower SEP was associated with an adverse hormone profile across multiple endocrine axes. SEP differences in endocrine function may partly underlie inequalities in health and function in later life, and may reflect variations in biological rates of ageing. Further studies are required to assess the likely functional relevance of these associations
Is vulnerability to cardiometabolic disease in Indians mediated by abdominal adiposity or higher body adiposity
No strong evidence supports that DXA measures or abdominal measures of adiposity are better at predicting the prevalence of cardiometabolic risk factors in comparison to BMI
OP17 Area Deprivation Across the Life Course and Cognitive Capability in Mid-Life
Background Recent work has shown that area conditions at single points in time have been found to be associated with cognitive capability outcomes. However, a life course perspective is required to take into account life time processes of cognitive development, changes in residence and secular trends of areas. Methods Data from the 1946 British Birth Cohort were used to estimate associations of area deprivation (indicated by % of employed people …
Benzodiazepine use and risk of dementia
BACKGROUND: Benzodiazepine use is widespread in older people, although its benefit is uncertain. AIM: To investigate the long-term effect of benzodiazepine use upon dementia risk. METHODS: A prospective cohort of men seen on five occasions over 22 years with full medication histories, repeat measures of cognitive function and a clinical diagnosis of dementia. RESULTS: Of 1134 men with complete data, 103 (9.1%) had been taking benzodiazepines regu…
Challenges in examining area effects across the life course on physical capability in mid-life
A major limitation of past work linking area socioeconomic conditions to health in mid-life has been the reliance on single point in time measurement of area. Using the MRC National Survey of Health and Development, this study for the first time linked place of residence at three major life periods of childhood (1950), young adulthood (1972), and mid-life (1999) to area-socioeconomic data from the nearest census years. Using objective measures of…
P2-303 Development of predictive equations for DXA measures of adiposity in an Indian population
Introduction Predictive equations for DXA measures of total and abdominal adiposity from simple anthropometry for an Indian population will enable more accurate estimates of adiposity to be derived in other studies. Methods Using 1230 men and 636 women from Hyderabad, India, multiple linear regression was performed to generate predictive equations for DXA measures of total body fat (grams) and total abdominal fat in the L1–L4 intervertebral regio…
P2-433 Nutritional supplementation in early life and future risk of obesity
Introduction Nutritional supplementation programmes for pregnant women and young children exist in much of the developing world, but their long term health consequences, particularly in the context of nutrition transition, are unknown. Methods The Hyderabad Nutrition Trial was a community trial to evaluate a supplemental nutrition programme for pregnant women and young children (<6 years), conducted in 29 villages (15 intervention, 14 control) ne…
P2-436 Rural-urban migration in relation to DXA measures of adiposity in India
Introduction India is experiencing an epidemic of obesity, diabetes and coronary disease. This epidemic is largely attributed to rapid urbanisation, driven in part by rural-urban migration. The aim of this study is to investigate whether rural-urban migration is related to DXA measures of adiposity within the Hyderabad arm of the Indian Migrant Study. Methods Migrants of rural origin, their rural dwelling sibs, and those of urban origin together …
P1-42 Associations of area deprivation over the lifecourse and physical capability in mid-life
Background Recent work has shown that factors across the whole of life influence physical capability in later life. Therefore, when investigating area socioeconomic effects on physical capability, area exposures should be assessed across the lifecourse to take account changes in residence and secular trends of an area. Methods Using data from the MRC National Survey of Health and Development, we examined the relationship between area low social c…
Magnitude and causes of mortality differences between married and unmarried men
STUDY OBJECTIVE--To determine the effect of marital status on mortality for men. In particular, to examine whether subgroups of unmarried men (widowed, single, and divorced/separated men) have a similar mortality to married men. DESIGN--Cohort study. SETTING--Whitehall civil service, London, between 1967 and 1969. PARTICIPANTS--A total of 18,403 men aged 40-64 years with 18 years' follow up. MEASUREMENTS AND MAIN RESULTS--Cause-specific mortality…
Genetic evidence of assortative mating in humans
Ethnicity, socio-economic position and gender-do they affect reported health-care seeking behaviour
Assessing equity in access to health care provision in the UK
STUDY OBJECTIVES--Equity should be monitored routinely for all health care services, but ideal studies for each service would be prohibitively expensive and time consuming. A simple, quick, and cheap method for the preliminary exploration of equity in health care provision using routine data was devised. This method was illustrated by examining whether coronary artery bypass graft (CABG) operations reflect socioeconomic differences in ischaemic h…
Gender differences in accessing cardiac surgery across England
Environmental equity, air quality, socioeconomic status, and respiratory health
Study objective: To assess relations between socioeconomic status and local air quality, and combined effects on respiratory health, in the context of environmental and health inequality. Design: Data on people taking part in the Health Survey for England were attributed with a small area index of air pollution using annual mean concentrations of nitrogen dioxide, sulphur dioxide, benzene, and particulates (PM 10 ). Regression models were used to…
Migration and social determinants of mental health
Challenges in examining area effects across the life course on physical capability in mid-life
A major limitation of past work linking area socioeconomic conditions to health in mid-life has been the reliance on single point in time measurement of area. Using the MRC National Survey of Health and Development, this study for the first time linked place of residence at three major life periods of childhood (1950), young adulthood (1972), and mid-life (1999) to area-socioeconomic data from the nearest census years. Using objective measures of…
Socio-economic disadvantage from childhood to adulthood and locomotor function in old age
BACKGROUND: Socio-economic influences over a lifetime impact on health and may contribute to poor physical functioning in old age. METHODS: The authors examined the impact of both childhood and adulthood socio-economic factors on locomotor function at 63-86 years (measured with the get up and go timed walk and flamingo balance test) in the UK-based Boyd Orr (n=405) and Caerphilly (n=1196) prospective cohorts. RESULTS: There was a marked reduction…
Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men
BACKGROUND: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. METHODS: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathe…
Prediction of general practice workload from census based social deprivation scores
STUDY OBJECTIVE--The aim was to compare the ability of census based social deprivation scores devised by Jarman, Carstairs, and Townsend to predict workload in general practice. DESIGN--This was a prospective study of 140,050 patients registered with general practices over one year from 1 July 1981 (Third National Morbidity Survey). Main outcome measures were workload score for each patient, defined as a weighted sum of consultations at the surge…
Frailty in older-age European migrants
Breast feeding and cardiovascular disease risk factors, incidence, and mortality
Study objective: To investigate the association of having been breast fed with cardiovascular disease risk factors, incidence, and mortality. Design: Prospective cohort study. Setting: Caerphilly, South Wales. Participants: All men aged 45–59 years living in and around the study area. Of 2818 eligible men, 2512 (89%) were seen. Altogether 1580 men (63%) obtained details of how they had been fed in infancy (ever breast fed or only bottle fed) from…
Better the donor you know? A qualitative study of renal patients' views on 'altruistic' live-donor kidney transplantation
Age-related inequalities in colon cancer treatment persist over time
BACKGROUND: Older people experience poorer outcomes from colon cancer. We examined if treatment for colon cancer was related to age and if inequalities changed over time. METHODS: Data from the UK population-based Northern and Yorkshire Cancer Registry on 31 910 incident colon cancers (ICD10 C18) diagnosed between 1999-2010 were obtained. Likelihood of receipt of: (1) cancer-directed surgery, (2) chemotherapy in surgical patients, (3) chemotherap…
Socioeconomic conditions across life related to multiple measures of the endocrine system in older adults
Lower SEP was associated with an adverse hormone profile across multiple endocrine axes. SEP differences in endocrine function may partly underlie inequalities in health and function in later life, and may reflect variations in biological rates of ageing. Further studies are required to assess the likely functional relevance of these associations
Benzodiazepine use and risk of dementia
BACKGROUND: Benzodiazepine use is widespread in older people, although its benefit is uncertain. AIM: To investigate the long-term effect of benzodiazepine use upon dementia risk. METHODS: A prospective cohort of men seen on five occasions over 22 years with full medication histories, repeat measures of cognitive function and a clinical diagnosis of dementia. RESULTS: Of 1134 men with complete data, 103 (9.1%) had been taking benzodiazepines regu…
What determines mortality risk in male former cigarette smokers
OBJECTIVES. The purpose of this study was to examine what factors determine the mortality experience of male ex-cigarette smokers, those who no longer smoke at all and those who changed to pipe or cigar smoking. METHODS. A cohort study was undertaken with 18-year mortality data on 19,018 men. RESULTS. Ex-cigarette smokers had an intermediate mortality risk compared with never and current smokers. Ex-cigarette smokers who switched to pipe smoking …
Deprivation in infancy or in adult life
The health of the nation
Prediction of general practice workload from census based social deprivation scores
STUDY OBJECTIVE--The aim was to compare the ability of census based social deprivation scores devised by Jarman, Carstairs, and Townsend to predict workload in general practice. DESIGN--This was a prospective study of 140,050 patients registered with general practices over one year from 1 July 1981 (Third National Morbidity Survey). Main outcome measures were workload score for each patient, defined as a weighted sum of consultations at the surge…
Social deprivation and premature mortality
OBJECTIVE--To investigate the pattern and size of the relationship between social deprivation in electoral wards and premature mortality for each health region in England. DESIGN--Ecological study using 1981 census variables and data on mortality for 1981-5. SETTING--14 regional health authorities in England. MAIN OUTCOME MEASURE--Mortality under the age of 65 years from all causes, coronary heart disease, and smoking related diseases in men and …
Health Expectancy
The Childhood Environment and Adult Disease
Magnitude and causes of mortality differences between married and unmarried men
STUDY OBJECTIVE--To determine the effect of marital status on mortality for men. In particular, to examine whether subgroups of unmarried men (widowed, single, and divorced/separated men) have a similar mortality to married men. DESIGN--Cohort study. SETTING--Whitehall civil service, London, between 1967 and 1969. PARTICIPANTS--A total of 18,403 men aged 40-64 years with 18 years' follow up. MEASUREMENTS AND MAIN RESULTS--Cause-specific mortality…
What determines mortality risk in male former cigarette smokers
OBJECTIVES. The purpose of this study was to examine what factors determine the mortality experience of male ex-cigarette smokers, those who no longer smoke at all and those who changed to pipe or cigar smoking. METHODS. A cohort study was undertaken with 18-year mortality data on 19,018 men. RESULTS. Ex-cigarette smokers had an intermediate mortality risk compared with never and current smokers. Ex-cigarette smokers who switched to pipe smoking …
Assessing equity in access to health care provision in the UK
STUDY OBJECTIVES--Equity should be monitored routinely for all health care services, but ideal studies for each service would be prohibitively expensive and time consuming. A simple, quick, and cheap method for the preliminary exploration of equity in health care provision using routine data was devised. This method was illustrated by examining whether coronary artery bypass graft (CABG) operations reflect socioeconomic differences in ischaemic h…
Does the variation in the socioeconomic characteristics of an area affect mortality?
Our research in England has shown that the more deprived an area the greater its incidence of premature mortality.1 Wilkinson has argued that in the developed world income distribution is a more important predictor of life expectancy between countries than simply mean income.2 We aimed to determine whether the risk of mortality in a geographical area was related to the degree of socioeconomic variation within that area as well as the average leve…
A Life Course Approach to Chronic Disease Epidemiology
Recent epidemiological research has forced us to question our current beliefs that the causes of coronary heart disease and cancer arise in adulthood. A new school of thought has emerged which argues that the chronic diseases prevalent in adult life have their origins during gestation, infancy, and childhood. A large body of evidence for this hypothesis has built up from research findings scattered throughout the scientific journals. In A life co…
Geographical and social class differentials in stroke mortality--the influence of early-life factors
The processes of cell proliferation, differentiation, migration, and self-organization during early embryonic development are governed by dynamic, spatially and temporally varying morphogen signals. Analogous tissue patterns emerge spontaneously in embryonic stem cell (ESC) models for gastrulation, but mechanistic insight into this self-organization is limited by a lack of molecular methods to precisely control morphogen signal dynamics. Here we …
Management of neurological disorders
Assessing the value of accreditation systems. E ScrivensThe relation between the number of symp- toms
Gender differences in accessing cardiac surgery across England
A life course approach to chronic disease epidemiology
Over the last few years there has been increasing interest in conceptualizing disease aetiology within a life course framework.1,2 This approach is not new to Public Health or unique to epidemiology (see below). However, its current resonance and interest within epidemiology reflects the challenging theoretical framework this approach provides. This issue of the International Journal of Epidemiology has several papers with a ‘life course theme’. …
Ethnicity, socio-economic position and gender-do they affect reported health-care seeking behaviour
A Life Course Approach to Chronic Disease Epidemiology
The field of life course epidemiology has expanded rapidly since this book was first published. The purpose of this field is to study how biological and social factors during gestation, childhood, adolescence, and earlier adult life independently, cumulatively, and interactively influence later life health and disease. Contributors to this edition capture the excitement of the developing field and assess the latest evidence regarding sources of r…
Gender and age inequity in the provision of coronary revascularisation in England in the 1990s
Breast feeding and cardiovascular disease risk factors, incidence, and mortality
Study objective: To investigate the association of having been breast fed with cardiovascular disease risk factors, incidence, and mortality. Design: Prospective cohort study. Setting: Caerphilly, South Wales. Participants: All men aged 45–59 years living in and around the study area. Of 2818 eligible men, 2512 (89%) were seen. Altogether 1580 men (63%) obtained details of how they had been fed in infancy (ever breast fed or only bottle fed) from…
Environmental equity, air quality, socioeconomic status, and respiratory health
Study objective: To assess relations between socioeconomic status and local air quality, and combined effects on respiratory health, in the context of environmental and health inequality. Design: Data on people taking part in the Health Survey for England were attributed with a small area index of air pollution using annual mean concentrations of nitrogen dioxide, sulphur dioxide, benzene, and particulates (PM 10 ). Regression models were used to…
A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity
Obesity is a serious international health problem that increases the risk of several common diseases. The genetic factors predisposing to obesity are poorly understood. A genome-wide search for type 2 diabetesâ susceptibility genes identified a common variant in the FTO (fat mass and obesity associated) gene that predisposes to diabetes through an effect on body mass index (BMI). An additive association of the variant with BMI was replicated in 1…
Does Anxiety Affect Risk of Dementia? Findings From the Caerphilly Prospective Study
Objective: To examine the association of anxiety with incident dementia and cognitive impairment not dementia (CIND). Methods: We conducted a prospective study of men aged 48 to 67 years at baseline anxiety assessment; we measured cognition 17 years later. We studied 1481 men who were either eligible for examination or were known to have dementia. Trait Anxiety was assessed using the Spielberger State Trait Anxiety Inventory. Psychological distre…
Is accelerated postnatal growth associated with blood pressure in childhood
Objective: To investigate whether variations in growth patterns in early-life are associated with blood pressure at age 6.5 years by modelling detailed, individual growth trajectories between birth and 5 years of age. Design: Prospective cohort study nested in a large randomised trial. Setting: Belarus. Participants: 10 494 children from Belarus who were born in one of 31 hospitals that participated in a cluster randomised trial of breastfeeding …
Comparison of the associations of BMI and measures of regional adiposity with coronary heart disease, diabetes and all cause mortality
Objective: To compare magnitudes of association of BMI and measures of regional adiposity with coronary heart disease, diabetes and all-cause mortality. Design: 2 prospective cohort and 2 cross sectional studies. Participants: Members of 4 UK cohorts aged >45 years: 3937 women from the British Women's Heart and Health Study (BWHHS), 2367 and 1950 men from phases 1 and 3 of the Caerphilly Prospective Study (CaPS), 403 men and women from Boyd Orr, …
The Effect of Rural-to-Urban Migration on Obesity and Diabetes in India
BACKGROUND: Migration from rural areas of India contributes to urbanisation and may increase the risk of obesity and diabetes. We tested the hypotheses that rural-to-urban migrants have a higher prevalence of obesity and diabetes than rural nonmigrants, that migrants would have an intermediate prevalence of obesity and diabetes compared with life-long urban and rural dwellers, and that longer time since migration would be associated with a higher…
Medicine (51 obras) · Demography (29 obras) · Gerontology (23 obras) · Gerontology (23 obras) · Internal Medicine (23 obras) · Population (23 obras) · Environmental health (20 obras) · Internal Medicine (20 obras) · Psychology (20 obras) · Health disparities and outcomes (18 obras)