Li Kuang
Dados Biográficos
| ID | 346763 |
|---|---|
| NOME | Li Kuang |
| PRENOMES | Li |
| SOBRENOME | Kuang |
| ASSINATURA | KUANG L |
| AFILIAÇÕES | The Affiliated Yongchuan Hospital of Chongqing Medical University |
| ORCID | 0000-0002-3265-2252 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 50 |
| TOTAL DE CITAÇÕES | 137 |
| TOTAL COMO AUTOR | 50 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2005 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 6 |
Clinical implications of admission anemia for electroconvulsive therapy planning in adolescent major depressive disorder
Admission anemia is associated with poorer ECT efficacy in adolescent MDD patients. Assessing baseline hemoglobin levels may help optimize ECT treatment planning, especially in female patients and those with psychotic depression
Neural responses to kills/deaths in real Moba games are associated with addiction-related psychological traits and subjective pleasant/unpleasant experiences
Restoration of mitochondrial energy metabolism by electroconvulsive therapy in adolescent and juvenile mice
This study systematically explored the potential mechanism by which ECT alleviates adolescent depression through the improvement of mitochondrial energy metabolism. The results indicate that ECT not only effectively alleviates depressive symptoms but also provides new insights and experimental evidence for the treatment of adolescent depression through mitochondrial function restoration. Future research could further investigate how to combine dr…
Case report
These preliminary findings suggest the potential of accelerated high-frequency tACS as a potential crisis intervention for adolescent MDD-SI, while highlighting the need for controlled clinical trials to establish efficacy and optimize stimulation parameters
Study pressure and self harm in Chinese primary school students
This study is the first to conduct a self-harm survey in the largest population-based sample of Chinese primary school students. The results highlight the importance of monitoring study pressure, fostering a positive parent-child relationship, and managing depressive symptoms to support students' mental health. These findings enhance our understanding of the development of self-harm behaviors and can inform the design of targeted intervention pro…
Application of machine learning in predicting adolescent Internet behavioral addiction
The detection rate of Internet addiction is higher in males than in females, and adolescents with impulsive, extroverted, psychotic, neurotic, obsessive, depressive, and hostile traits are more prone to developing Internet addiction. While the overall performance of the machine learning models for predicting adolescent Internet addiction is moderate, the extreme gradient boosting method outperforms others, effectively identifying risk factors and…
High-intensity transcranial alternating current stimulation combined with pharmacotherapy for adolescent major depressive disorder
The combination of HI-tACS and pharmacotherapy demonstrated potential early effects in this small cohort of adolescents with MDD, particularly during the initial phase of treatment. These preliminary findings warrant further investigation through large-scale randomized controlled trials to establish efficacy and safety profiles, and to further characterize suicide risk trajectories
Impaired response inhibition to negative emotional stimuli in depressed adolescents with non-suicidal self-injury
Depressed adolescents with NSSI showed increased P3d amplitudes, enhanced Delta/Theta ERS, and heightened Theta/Alpha ERD when receiving negative emotional stimuli, suggesting that depressed adolescents with NSSI have impaired response inhibition, which may contribute to the development of NSSI
Application of the “hospital-school-home-community” integrated mental health service model for primary and secondary school students in Chongqing, China
The "Hospital-School-Home-Community" integrated mental health service model has demonstrated success in improving child and youth mental health within the school setting in Chongqing. It has effectively linked education and health systems to address a full continuum of care
Exploring the profile and risk factors associated with self-harm ideation and behaviors in adolescents with high psychoticism
Our findings highlight the critical need for targeted interventions addressing modifiable determinants. Prioritizing female adolescents and those with higher psychoticism traits is recommended, supported by evidence-based family psychoeducation programs and enhanced accessibility of community mental health services with specific focus on emotion regulation training
The effects of parent-child relationship, study stress, and mobile phone use on depressive symptoms among Chinese elementary school students
These results emphasize the importance of nurturing parent-child relationship, monitoring study stress, and managing mobile phone usage to support students' mental health. Furthermore, the findings suggest that the impact of mobile phone usage on the mental health of elementary school students varies in complexity across different parent-child relationship contexts, providing valuable insights and recommendations for developing targeted preventiv…
Takeaway food consumption and depressive symptoms in Chinese university students
The study highlights the negative relationship between takeaway frequency and emotional well-being, emphasizing the need to focus on the emotional health of frequent takeaway food consumers. Moreover, our study suggests that increased physical activity may alleviate takeaway-induced mood-related outcomes
A comparative study of anxiety symptoms in Chinese and Rwandan adolescents
The GAD-7 showed reliability in measuring generalized anxiety in both Chinese and Rwandese adolescents, confirming its cross-cultural construct validity. However, partial scalar invariance suggests that while the GAD-7 effectively detects anxiety symptoms, the severity of reported symptoms may not be directly comparable across cultures due to response patterns and possible linguistic factors. These findings highlight the importance of culturally …
Impulsivity and social support as intervening and interactive variables in the link between childhood socioeconomic status and mental health among first-year college students
Our findings demonstrate that impulsivity serves as a partial intervening variable in the relationship between childhood SES and the mental health of first-year college students. However, higher levels of social support were linked to weaker negative associations between impulsivity and both childhood SES and mental health. Interventions that focus on managing impulsivity and increasing social support for first-year college students from low soci…
Serum HMGB1 as a diagnostic biomarker and mediator of childhood trauma in adolescent depression
Serum HMGB1 levels are potential markers of depression, and childhood trauma partially mediates the relationship between HMGB1 and depressive symptoms severity
Research on prediction model of adolescent suicide and self-injury behavior based on machine learning algorithm
The detection rate of suicidal and self-injurious behaviors is higher in women than in men. Adolescents displaying impulsiveness, psychoticism, neuroticism, interpersonal sensitivity, depression, and paranoia have a greater likelihood of engaging in such behaviors. The machine learning model for classifying and predicting adolescent suicide and self-injury risk effectively identifies these behaviors, enabling targeted interventions
Transforming growth factor-β superfamily members as potential biomarkers for adolescent major depressive disorder
Serum TGF-β1, GDF11, and GDF15 levels may serve as promising biomarkers for adolescent MDD, offering potential utility in identifying disease susceptibility. These findings highlight the TGF-β superfamily's role in adolescent depression and warrant further mechanistic investigation
Dose-response relationship between different physical activity types and depressive symptoms in middle-aged and elderly people
Our study found a non-linear dose correlation between physical activities and depressive symptoms. The dose-response connection between different physical activity types and depressive symptoms varies between rural and urban areas. Recreational physical activity is recommended for urban and reasonable amounts of nonrecreational physical activity for rural populations to reduce the risk of depressive symptoms. However, causal interpretations canno…
Effects of varying longitudinal bending stiffness in running shoes on lower limb biomechanics of elite marathon runners
This study demonstrates that increasing the LBS shoes alters the lower limb biomechanical performance of elite marathon runners. Both MLBS and HLBS conditions reduced MTP joint dorsiflexion, but MLBS shoes significantly increased positive work at the ankle joint and improved joint function while maintaining lower hip joint moments. Among the three conditions, MLBS better balanced mechanical efficiency and natural joint function, suggesting it may…
Wildfires and social media discourse
Introduction: The rise in global temperatures due to climate change has escalated the frequency and intensity of wildfires worldwide. Beyond their direct impact on physical health, these wildfires can significantly impact mental health. Conventional mental health studies predominantly rely on surveys, often constrained by limited sample sizes, high costs, and time constraints. As a result, there is an increasing interest in accessing social media…
Assessing anxiety symptom severity in Rwandese adolescents
The GAD-7 can be used in cross-group comparison of generalized anxiety disorder prevalence, and we acknowledge that full scalar invariance is generally difficult to confirm, especially due to gender differences. We recommend that future studies further investigate populations living in rural areas and conduct trials that will focus on anxiety-specific treatment in Rwandan Clinical health care centers to determine the diagnostic accuracy of this s…
Effects of electroconvulsive therapy on inflammatory markers and depressive symptoms in adolescents with major depressive disorder
While initial inflammatory marker levels did not predict the response to ECT, the post-treatment measures appeared to be linked to clinical improvement. These findings suggest ECT's potential effectiveness in treating severe MDD in adolescents and point to the possible predictive value of inflammatory markers in therapeutic outcomes. The study contributes to our understanding of the biopsychosocial framework of MDD and indicates that ECT may be a…
Association of the neutrophil-to-platelet ratio with response to electroconvulsive therapy in adolescents with major depressive disorder
High NPR correlates with poor ECT efficacy in adolescents with MDD, particularly among female and overweight patients
A propensity score matching study
Background The 2019 coronavirus disease (COVID-19) pandemic increased the risks of mental health challenges, especially anxiety and depression. However, the impact of COVID-19 on mental health during pregnancy has not been fully established. Therefore, we investigated the impact of the COVID-19 pandemic on maternal mental health. Methods Two cohorts of pregnant women at their first antenatal care in the First Affiliated Hospital of Chongqing Medi…
Abnormal brain spontaneous activity in major depressive disorder adolescents with non-suicidal self injury and its changes after sertraline therapy
The abnormal functional neuronal activity found at frontal and occipital cortex implied cognitive and affective disturbances in adolescent nsMDDs. The trend of upregulation of frontal neuronal activity and downregulation of occipital neuronal activity after sertraline treatment indicated that the therapy could be effective in regulating the abnormality. Notably, the significantly decreased neuronal activity in the decision related orbital middle …
The Dynamics of Economic Disadvantage and Children's Life Chances
Recent research suggests that child well-being and subsequent status attainment are influenced not only by the duration of exposure to economic disadvantage during childhood, but also by the timing and sequencing of exposure. Unfortunately, traditional measures of children's economic deprivation typically fail to differentiate between exposures to disadvantage at different stages in childhood and largely ignore how economic circumstances change o…
Psychological resilience, depression, anxiety, and somatization symptoms in response to Covid-19
Rethinking Research on Forming Typologies of Homelessness
In homelessness research and policymaking, it seems to be axiomatic that single adults experience 3 temporally based types of homelessness: chronic, episodic, and transitional. We discuss problems with the theorization of this typology and with the research design, data analysis, and time-aggregated conceptualization and measurement of temporality in the empirical work supporting the typology. To address the latter, we suggest a time-patterned ap…
Capturing Intervention Effects Over Time
Objectives. We analyzed whether a method for identifying latent trajectories—latent class growth analysis (LCGA)—was useful for understanding outcomes for individuals subject to an intervention. Methods. We used LCGA to reanalyze data from a published study of mentally ill homeless men in a critical time intervention (CTI) program. In that study, 96 men leaving a shelter’s onsite psychiatric program were randomly assigned to experimental and cont…
Typologizing Temporality
This article employs a relatively new method to construct time‐based typologies of homelessness, arguing that time‐aggregated typologies in previous research lose useful information by summing, averaging, or otherwise summarizing events that occur over time. This study instead proposes a time‐patterned approach that measures the timing, duration, and sequence of events as they unfurl over time. It first compares the two approaches by examining su…
Parental Health and Children's Economic Well-Being
The life course perspective emphasizes that past economic experiences and stage in the life course influence a family's ability to cope with negative life events such as poor health. However, traditional analytic approaches are not well-suited to examine how the impact of negative life events differs based on a family's past economic experiences, nor do they typically account for the potentially spurious association between negative life events a…
Assessment of Risk Factors for Low Birth Weight Deliveries
Recognition of a higher than average incidence of low birth weight (LBW) deliveries in areas of Eastern Pennsylvania led to an analysis of more than 5,500 deliveries in one of the region's hospital systems to investigate the predictors of LBW in that population. Results of multivariate analysis indicate key variables that contribute to LBW: in particular, racial/ethnic background and specific medial problems during pregnancy, including preeclamps…
Capturing Intervention Effects Over Time
Objectives. We analyzed whether a method for identifying latent trajectories—latent class growth analysis (LCGA)—was useful for understanding outcomes for individuals subject to an intervention. Methods. We used LCGA to reanalyze data from a published study of mentally ill homeless men in a critical time intervention (CTI) program. In that study, 96 men leaving a shelter’s onsite psychiatric program were randomly assigned to experimental and cont…
The Dynamics of Economic Disadvantage and Children's Life Chances
Recent research suggests that child well-being and subsequent status attainment are influenced not only by the duration of exposure to economic disadvantage during childhood, but also by the timing and sequencing of exposure. Unfortunately, traditional measures of children's economic deprivation typically fail to differentiate between exposures to disadvantage at different stages in childhood and largely ignore how economic circumstances change o…
Parental Health and Children's Economic Well-Being
The life course perspective emphasizes that past economic experiences and stage in the life course influence a family's ability to cope with negative life events such as poor health. However, traditional analytic approaches are not well-suited to examine how the impact of negative life events differs based on a family's past economic experiences, nor do they typically account for the potentially spurious association between negative life events a…
Typologizing Temporality
This article employs a relatively new method to construct time‐based typologies of homelessness, arguing that time‐aggregated typologies in previous research lose useful information by summing, averaging, or otherwise summarizing events that occur over time. This study instead proposes a time‐patterned approach that measures the timing, duration, and sequence of events as they unfurl over time. It first compares the two approaches by examining su…
Rethinking Research on Forming Typologies of Homelessness
In homelessness research and policymaking, it seems to be axiomatic that single adults experience 3 temporally based types of homelessness: chronic, episodic, and transitional. We discuss problems with the theorization of this typology and with the research design, data analysis, and time-aggregated conceptualization and measurement of temporality in the empirical work supporting the typology. To address the latter, we suggest a time-patterned ap…
Equity in patient experiences of primary care in community health centers using primary care assessment tool
Equity in the primary care patient experiences between rural-to-urban migrants and urban locals seems to have been achieved to some extent. However, there is room for improvement in the equity of coordination of care and comprehensiveness. Policy makers should consider strengthening these two dimensions by integrating the health care system. More attention should be focused on helping migrants break down language and cultural barriers and improvi…
Relationship between Internet addiction, susceptible personality traits, and suicidal and self-harm ideation in Chinese adolescent students
Association between Primary Healthcare and Medical Expenditures in a Context of Hospital-Oriented Healthcare System in China
Total health expenditure in China has grown considerably since a new round of health system reform was enacted in 2009. Researchers have shown that strengthening primary healthcare may be an option for countries to solve the rapid expansion of their medical expenditures. This study was designed to explore the association between the strength of primary healthcare and medical expenditures, in the context of the hospital-oriented healthcare system …
Association of primary care physician supply with maternal and child health in China
The sufficient supply of primary care physician was associated with improved maternal and child health outcomes in China, especially in the less-developed western region. Policies on effective and proportional allocation of resources should be made and conducted to strengthen primary care system and eliminate geographical disparities
Psychological resilience, depression, anxiety, and somatization symptoms in response to Covid-19
The Association Between Resting State Functional Connectivity and the Trait of Impulsivity and Suicidal Ideation in Young Depressed Patients With Suicide Attempts
Suicide is a leading cause of death among youth and is strongly associated with major depressive disorder (MDD). However, the neurobiological underpinnings of suicidal behaviour and the identification of risk for suicide in young depressed patients are not yet well-understood. In this study, we used a seed-based correlation analysis to investigate the differences in resting-state functional connectivity (RSFC) in depressed youth with or without a…
Disruption of Neural Activity and Functional Connectivity in Adolescents With Major Depressive Disorder Who Engage in Non-suicidal Self-Injury
Background: Non-suicidal self-injury (NSSI), which commonly occurs during adolescence, often co-occurs with major depressive disorder (MDD). However, the underlying neurobiological mechanisms in adolescents with MDD who engage in NSSI remain unclear. The current study examined the aberrant local neural activity in certain areas of the visual regions and the default mode network (DMN) and the resting-state functional connectivity (rs-FC) in change…
Effect of Family Practice Contract Services on the Perceived Quality of Primary Care among Patients with Multimorbidity
Family practice contract services, an important primary-care reform policy for improving primary healthcare quality in China, incorporate patients with multiple chronic conditions into the priority coverage groups and focus on their management. This study aims to explore the family practice contract services' effectiveness in improving the quality of primary care experienced by this population. A cross-sectional study using a three-stage sampling…
Development and Validation of a Rapid Assessment Version of the Assessment Survey of Primary Care in China
Background: Measuring quality of primary care has attracted much attention around the world. Our team has developed and validated an Assessment Survey of Primary Care (ASPC) for evaluating quality of primary care in China. To facilitate the daily use of ASPC, this study aimed to develop and validate a rapid assessment version of ASPC (RA-ASPC) in China. Methods: This is a multi-phase study on 21 experts and 1,184 patients from 12 primary care fac…
The difference of disrupted rhythms of life, work and entertainment between patients with FGIDs and healthy people and their associations with psychological disorders under Covid-19 pandemic
Aims: To investigate the differences in disrupted rhythms between healthy people and patients with functional gastrointestinal disorders (FGIDs) and their associations with mood disorders during the coronavirus disease 2019 (COVID-19) pandemic. Methods: The rhythm scales were composed of subscales 1 and 2 for the assessment of life-work and entertainment rhythms, respectively; Zung’s Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scal…
Attitudes Toward Psychiatry Among Medical Students With a Psychiatric Major at Chongqing Medical University
Students generally have good expectations toward psychiatry, but different opinions are also held and the field is still faced with various challenges in order to provide more psychiatrists
Altered Neural Reactivity in Adolescents With Nonsuicidal Self-Injury During Exposure to Self-Injury Related Cues
Adolescents with NSSI showed altered neural reactivity during exposure to self-injury cue. Further studies with larger sample sizes are needed to confirm our results
Changes in gray matter volume following electroconvulsive therapy in adolescent depression with suicidal ideation
Frontal-temporal-precuneus structure changes may be a potential cause of depressive and suicidal symptoms in adolescents. ECT may improve depressive and suicidal symptoms in adolescents by regulating brain structures to compensate original defects
A Resting State Functional Magnetic Resonance Imaging Study of Unmedicated Adolescents With Non-suicidal Self-Injury Behaviors
We found that in ALFF, fALFF and ReHo, the significant differences between nsMDDs and nnsMDDs are mainly located in default mode network (DMN) and visual network (VN), and there may be brain regions related to NSSI in DMN and VN. The significant differences brain regions in ALFF, fALFF and ReHo between nsMDDs and nnsMDDs were related to the total score of the relevant clinical psychological scale, and may be related to NSSI
Association between Primary Care Utilization and Emergency Room or Hospital Inpatient Services Utilization among the Middle-Aged and Elderly in a Self-Referral System
With rapid economic growth and aging, hospital inpatient and emergency services utilization has grown rapidly, and has emphasized an urgent requirement to adjust and optimize the structure of health service utilization. Studies have shown that primary care is an effective way to reduce inpatient and emergency room (ER) service utilization. This study aims to examine whether middle-aged and elderly individuals who selected primary care outpatient …
A propensity score matching study
Background The 2019 coronavirus disease (COVID-19) pandemic increased the risks of mental health challenges, especially anxiety and depression. However, the impact of COVID-19 on mental health during pregnancy has not been fully established. Therefore, we investigated the impact of the COVID-19 pandemic on maternal mental health. Methods Two cohorts of pregnant women at their first antenatal care in the First Affiliated Hospital of Chongqing Medi…
Abnormal brain spontaneous activity in major depressive disorder adolescents with non-suicidal self injury and its changes after sertraline therapy
The abnormal functional neuronal activity found at frontal and occipital cortex implied cognitive and affective disturbances in adolescent nsMDDs. The trend of upregulation of frontal neuronal activity and downregulation of occipital neuronal activity after sertraline treatment indicated that the therapy could be effective in regulating the abnormality. Notably, the significantly decreased neuronal activity in the decision related orbital middle …
Impaired behavioral inhibitory control of self-injury cues between adolescents with depression with self-injury behavior and those without during a two-choice oddball task
These findings contribute to substantial progress in exploring neuro-electrophysiological evidence of self-injury behaviors. Furthermore, the difference between the NSSI and suicide groups might be the direction of prediction of suicidality
Severity related neuroanatomical and spontaneous functional activity alteration in adolescents with major depressive disorder
The abnormal structural and functional findings at cortico-subcortical areas implied the dysfunctional cognitive control and emotional regulations in adolescent depression. The findings might help elaborate the underlying neural mechanisms of MDD in adolescents
Medicine (37 obras) · Psychology (37 obras) · Psychiatry (29 obras) · Clinical Psychology (26 obras) · Clinical Psychology (22 obras) · Depression (economics (13 obras) · Major depressive disorder (13 obras) · Cognition (10 obras) · Developmental psychology (10 obras) · Suicide and Self-Harm Studies (10 obras)