Zhengming Chen
Dados Biográficos
| ID | 3862020 |
|---|---|
| NOME | Zhengming Chen |
| PRENOMES | Zhengming |
| SOBRENOME | Chen |
| ASSINATURA | CHEN Z |
| AFILIAÇÕES | University of Oxford |
| ORCID | 0000-0001-9437-6452 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 38 |
| TOTAL DE CITAÇÕES | 36 |
| TOTAL COMO AUTOR | 38 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2011 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 3 |
The COPD risk associated with adulthood weight change and early adulthood BMI
Gaps concerning general adiposity and chronic obstructive pulmonary disease (COPD) are delaying policies for weight interventions in COPD prevention, especially adiposity in early adulthood and weight changes during adulthood. Based on the China Kadoorie Biobank, a prospective cohort between 2004–2008 covering 5 urban and 5 rural areas, we included 138,764 males and 194,159 females aged 35 ~ 70 years. Weight change was defined as the difference b…
Sleep quality and incidence of diabetes in 0.5 million Chinese adults
Poor sleep quality is comparable to traditional risk factors for diabetes. This study evaluated the association between sleep quality index (SQI) and the risk of diabetes incidence in China. We used data from the China Kadoorie Biobank, comprising 462,743 participants aged 30 to 79 years without diabetes at baseline, who were recruited between 2004 and 2008 from ten diverse regions across China. We developed a SQI to assess sleep quality, based o…
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are conducted through family-based variance analyses, which are more robust to the systemic biases that impact population-based methods. We combined da…
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality
Objectives: The characteristics of multimorbidity in the Chinese population are currently unclear. We aimed to determine the temporal change in multimorbidity prevalence, clustering patterns, and the association of multimorbidity with mortality from all causes and four major chronic diseases. Methods: This study analyzed data from the China Kadoorie Biobank study performed in Wuzhong District, Jiangsu Province. A total of 53,269 participants aged…
Preserved vegetable consumption and gastrointestinal tract cancers
Background: This study aimed to assess the associations of two common types of preserved vegetables in China, salted and sour pickled vegetables, with the risk of gastrointestinal tract (GI) cancers, including oesophageal cancer, stomach cancer, and colorectal cancer. Methods: The China Kadoorie Biobank collected intake frequency of preserved vegetables among 510 143 adults without self-reported cancer during 2004-2008, and followed up till 31 De…
Strengthening China’s National Essential Public Health Services Package for hypertension and diabetes care
The study has been registered on Chinese Clinical Trial Registry at https://www.chictr.org.cn/ (Registration number ChiCTR2400082036, on March 19th 2024)
Methods and participant characteristics in the Cancer Risk in Vegetarians Consortium
Food intakes and lifestyle factors of both non-vegetarians and vegetarians varied markedly across the individual cohorts, which may be due to differences in both culture and socioeconomic status, as well as differences in questionnaire design. Therefore, care is needed in the interpretation of the impacts of vegetarian diets on cancer risk
The experience of tobacco withdrawal symptoms among current smokers and ex-smokers in the general population
Objective To clarify the extent to which smokers in the general population experience tobacco withdrawal symptoms and whether such experience differs in those who continue to smoke and those who stopped smoking. Methods We included relevant questions in the nationally-representative China Health Literacy Survey (CHLS) conducted in 2018–2019. Among 87,028 participants, there were 22,115 ever-smokers aged 20–69 years who provided information on the…
Revisiting the China Mission of Mikhail Borodin in 1923–1927
Healthy lifestyle and life expectancy free of major chronic diseases at age 40 in China
Cooking and future risk of all-cause and cardiopulmonary mortality
Body-mass index and obesity in urban and rural China
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
The association between daily total physical activity and risk of cardiovascular disease among hypertensive patients
Total daily physical activity was negatively associated with CVDs among hypertensive adults in China, and this association was U-shape. It has some public health implications that community-based total physical activity intervention campaigns can be of help for CVDs prevention among hypertensive people in China
Feasibility and validity of using death surveillance data and SmartVA for fact and cause of death in clinical trials in rural China
BACKGROUND: In rural China, mortality surveillance data may be an alternative to primary data collection in clinical trials; SmartVA (verbal autopsy) is also a potential alternative for endpoint adjudication. The feasibility and validity of both need to be assessed. METHODS: We used mortality data from the first 24 months of the China Salt Substitute and Stroke Study (SSaSS) trial and assessed the agreement between (1) mortality surveillance data…
Educational disparities in ischaemic heart disease among 0.5 million Chinese adults
Background The relationship between educational attainment and ischaemic heart disease (IHD) is limited in evidence in middle-income countries like China. Exploring lifestyle-related mediators, which might be not universal between socioeconomic status and health outcomes in diverse regions, can contribute to interventions targeted at the Chinese to narrow the educational gap in IHD. Methods Based on the China Kadoorie Biobank of 489 594 participa…
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Frailty index and all-cause and cause-specific mortality in Chinese adults
BackgroundThe fraily index is a useful proxy measure of accelerated biological ageing and in estimating all-cause and cause-specific mortality in older individuals in European and US populations. However, the predictive value of the frailty index in other populations outside of Europe and the USA and in adults younger than 50 years is unknown. We aimed to examine the association between the frailty index and mortality in a population of Chinese a…
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Patterns and trends of alcohol consumption in rural and urban areas of China
Among Chinese men, the proportion of drinkers engaging in harmful drinking behaviours increased in the past decade, particularly among younger men. Harmful drinking patterns tended to cluster with other unhealthy lifestyles and health-related risk factors
Association between multiple comorbidities and self-rated health status in middle-aged and elderly Chinese
Various diseases were major determinants of global and age-comparative SRH, and cardiometabolic diseases had the strongest impact on both global SRH and age-comparative SRH at the population level. Prevention measures concentrated on these conditions would greatly reduce the total burden of poor SRH and its consequences such as poor quality of life and use of health care services
Diabetes, plasma glucose and incidence of colorectal cancer in Chinese adults
Background Diabetes is associated with higher risk of colorectal cancer (CRC). Uncertainty remains about the relevance of duration of diabetes and about the association of blood glucose with CRC risk among individuals without diabetes. Methods The prospective China Kadoorie Biobank recruited 512 713 participants in 2004–2008 from 10 diverse areas in China. After 10 years of follow-up, 3024 incident cases of CRC (1745 colon, 1716 rectal) were reco…
Worldwide trends in blood pressure from 1975 to 2015
BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. METHODS: For this analysis, we pooled national, subnational, or comm…
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…
Globalization and Gender Wage Inequality in China
Foreign Direct Investment and Wage Inequality
Prevalence and patterns of tobacco smoking among Chinese adult men and women
BACKGROUND: China consumes about 40% of the world's cigarettes, predominantly by men, following a large increase in recent decades. We assess sex-specific prevalence and changing patterns of smoking in Chinese adults in the current decade. METHODS: A nationally representative survey of smoking was conducted in 2010 among 100 000 Chinese adults aged ≥18 years, using a multistage stratified cluster sampling method. Information on smoking frequency,…
Educational disparities in ischaemic heart disease among 0.5 million Chinese adults
Background The relationship between educational attainment and ischaemic heart disease (IHD) is limited in evidence in middle-income countries like China. Exploring lifestyle-related mediators, which might be not universal between socioeconomic status and health outcomes in diverse regions, can contribute to interventions targeted at the Chinese to narrow the educational gap in IHD. Methods Based on the China Kadoorie Biobank of 489 594 participa…
The frontier crisis and the construction of modern Chinese geography in Republican China (1911–1949)
The article probes into the connection between territorial nationalism and the disciplinary formation of modern geography in early twentieth-century China. It explores how a group of Republican Chinese geographers, such as Zhu Kezhen 竺可楨 (1890–1974), Hu Huanyong 胡煥庸 (1901–1998), and Zhang Qiyun張其昀 (1900–1985), reexamined Chinese traditional dynastic geography (yange dili) and defined the nature and methodology of what they called the “new geograp…
Foreign Direct Investment and Wage Inequality
O2-5.4 Overview and development for policies on sharing prospective epidemiological data
Introduction With the establishment of prospective bio-bank studies around the world and need for better collaborative use of the resources, there is growing demand for open data sharing both from funders and the research community. However, there is no standard framework for their data sharing policies. Methods From numerous websites and publications, we identified large (N≥50 000) well-established population-based studies of common non-communic…
P2-66 Physical activity and its associations with prevalence of overweight, hypertension, diabetes and ischaemic heart disease in the Kadoorie Biobank study of 0.5 million people in China
Introduction Physical activity is associated with cardiovascular risk in Western populations but evidence from the Chinese population is limited. Methods We examined baseline data on over 500 000 people aged 30–79 years who, during 2004–2008, were recruited into a prospective study from 10 regions in China. Information on physical activity was collected using an interviewer-administered questionnaire that enquired about the frequency, duration an…
Globalization and Gender Wage Inequality in China
Respiratory risks from household air pollution in low and middle income countries
Patterns and socio-demographic correlates of domain-specific physical activities and their associations with adiposity in the China Kadoorie Biobank study
In Chinese adults, physical activity mainly involves occupation and housework, with little from active-recreational activity. Domain-specific physical activities varied by socio-demographic factors and had different associations with adiposity
Spicy food consumption is associated with adiposity measures among half a million Chinese people
The data indicate that spicy food intake is a risk factor for obesity in Chinese adult population, especially for central obesity in males. Further studies are needed to elucidate the mechanisms underlying this association
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013
Body-mass index and all-cause mortality
Romance with the periphery
During the Nanjing Decade (1927-1937), amid a context of foreign encroachment on China’s frontiers and surging Chinese nationalism, frontier travel arose in popularity and took on special significance. Many Han intellectuals and officials travelled to the frontiers. They left a copious body of literature discussing their experiences. Through reading some key travel accounts, especially those by Dai Jitao (戴季陶), Ma Hetian (马鹤天), and Fan Changjiang…
The frontier crisis and the construction of modern Chinese geography in Republican China (1911–1949)
The article probes into the connection between territorial nationalism and the disciplinary formation of modern geography in early twentieth-century China. It explores how a group of Republican Chinese geographers, such as Zhu Kezhen 竺可楨 (1890–1974), Hu Huanyong 胡煥庸 (1901–1998), and Zhang Qiyun張其昀 (1900–1985), reexamined Chinese traditional dynastic geography (yange dili) and defined the nature and methodology of what they called the “new geograp…
Worldwide trends in blood pressure from 1975 to 2015
BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. METHODS: For this analysis, we pooled national, subnational, or comm…
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…
Prevalence and patterns of tobacco smoking among Chinese adult men and women
BACKGROUND: China consumes about 40% of the world's cigarettes, predominantly by men, following a large increase in recent decades. We assess sex-specific prevalence and changing patterns of smoking in Chinese adults in the current decade. METHODS: A nationally representative survey of smoking was conducted in 2010 among 100 000 Chinese adults aged ≥18 years, using a multistage stratified cluster sampling method. Information on smoking frequency,…
Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer
Association between multiple comorbidities and self-rated health status in middle-aged and elderly Chinese
Various diseases were major determinants of global and age-comparative SRH, and cardiometabolic diseases had the strongest impact on both global SRH and age-comparative SRH at the population level. Prevention measures concentrated on these conditions would greatly reduce the total burden of poor SRH and its consequences such as poor quality of life and use of health care services
Diabetes, plasma glucose and incidence of colorectal cancer in Chinese adults
Background Diabetes is associated with higher risk of colorectal cancer (CRC). Uncertainty remains about the relevance of duration of diabetes and about the association of blood glucose with CRC risk among individuals without diabetes. Methods The prospective China Kadoorie Biobank recruited 512 713 participants in 2004–2008 from 10 diverse areas in China. After 10 years of follow-up, 3024 incident cases of CRC (1745 colon, 1716 rectal) were reco…
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Patterns and trends of alcohol consumption in rural and urban areas of China
Among Chinese men, the proportion of drinkers engaging in harmful drinking behaviours increased in the past decade, particularly among younger men. Harmful drinking patterns tended to cluster with other unhealthy lifestyles and health-related risk factors
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Frailty index and all-cause and cause-specific mortality in Chinese adults
BackgroundThe fraily index is a useful proxy measure of accelerated biological ageing and in estimating all-cause and cause-specific mortality in older individuals in European and US populations. However, the predictive value of the frailty index in other populations outside of Europe and the USA and in adults younger than 50 years is unknown. We aimed to examine the association between the frailty index and mortality in a population of Chinese a…
Body-mass index and obesity in urban and rural China
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
The association between daily total physical activity and risk of cardiovascular disease among hypertensive patients
Total daily physical activity was negatively associated with CVDs among hypertensive adults in China, and this association was U-shape. It has some public health implications that community-based total physical activity intervention campaigns can be of help for CVDs prevention among hypertensive people in China
Feasibility and validity of using death surveillance data and SmartVA for fact and cause of death in clinical trials in rural China
BACKGROUND: In rural China, mortality surveillance data may be an alternative to primary data collection in clinical trials; SmartVA (verbal autopsy) is also a potential alternative for endpoint adjudication. The feasibility and validity of both need to be assessed. METHODS: We used mortality data from the first 24 months of the China Salt Substitute and Stroke Study (SSaSS) trial and assessed the agreement between (1) mortality surveillance data…
Medicine (29 obras) · Environmental health (22 obras) · Demography (19 obras) · Population (18 obras) · China (11 obras) · Internal Medicine (11 obras) · Obesity, Physical Activity, Diet (10 obras) · Body mass index (9 obras) · Gerontology (9 obras) · Sociology (9 obras)