Adrianna Murphy
Dados Biográficos
| ID | 3928057 |
|---|---|
| NOME | Adrianna Murphy |
| PRENOMES | Adrianna |
| SOBRENOME | Murphy |
| ASSINATURA | MURPHY A |
| AFILIAÇÕES | London School of Hygiene & Tropical Medicine |
| ORCID | 0000-0003-4065-6744 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 17 |
| TOTAL DE CITAÇÕES | 14 |
| TOTAL COMO AUTOR | 17 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2013 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 1 |
‘You can sleep hungry just to buy the medicine’
This research applies the Cumulative Complexity model to examine patient experiences of hypertension management following prescription of anti-hypertensive medication in the public health system in Kenya. Set in Kiambu County, central Kenya, it draws on abductive analysis of interviews with patients (n = 24), caregivers (n = 7) and non-participant observation in four purposively selected public facilities conducted between November 2022 and April…
Implementation strategies to improve outcomes in patients with established cardiovascular disease in sub-Saharan Africa
Sub-Saharan Africa (SSA) is experiencing an epidemic of cardiovascular disease (CVD). Despite numerous evidence-based therapies and management guidelines for patients with acute or established CVD, significant gaps persist in their implementation in SSA. This systematic review aims to describe, synthesise and identify key gaps in the implementation strategies of evidence-based approaches that can improve clinical outcomes for patients with acute …
Acceptability of fixed-dose combination treatments for hypertension in Kenya
Fixed-dose combinations (FDCs) – 2-3 anti-hypertensive medications in a single pill - have the potential to improve hypertension treatment and outcomes. Yet, they are not widely implemented. Factors undermining implementation remain unknown, particularly in sub–Saharan Africa, where hypertension is a major cause of disease burden and is poorly controlled. This study explored the acceptability of FDCs among patients, caregivers, and healthcare wor…
Managing diabetes and hypertension in western Kenya
The Primary Health Integrated Care for Chronic Conditions (PIC4C) pilot project was launched in 2018 to strengthen prevention and control of four non-communicable conditions at primary health care level in western Kenya. We conducted a qualitative study to explore the extent to which PIC4C integrated services supported people with hypertension and/or diabetes towards timely diagnosis and referral, treatment, follow-up and adherence, from the pers…
Comparing estimates of household expenditures between pictorial diaries and surveys in three low- and middle-income countries
In most low- and middle-income countries (LMICs), household out-of-pocket (OOP) health spending constitutes a major source of healthcare financing. Household surveys are commonly used to monitor OOP health spending, but are prone to recall bias and unable to capture seasonal variation, and may underestimate expenditure–particularly among households with long-term chronic health conditions. Household expenditure diaries have been developed as an a…
Understanding the treatment burden of people with chronic conditions in Kenya
In Kenya, non-communicable diseases (NCDs) are an increasingly important cause of morbidity and mortality, requiring both better access to health care services and self-care support. Evidence suggests that treatment burdens can negatively affect adherence to treatment and quality of life. In this study, we explored the treatment and self-management burden among people with NCDs in in two counties in Western Kenya. We conducted a cross-sectional s…
Evaluating the effectiveness of the National Health Insurance Fund in providing financial protection to households with hypertension and diabetes patients in Kenya
We did not find strong evidence that the NHIF national scheme is effective in providing financial risk protection to households with individuals living with hypertension and/diabetes in Kenya. This could partly be explained by the low depth of cover of the NHIF national scheme, and the high attrition rate. To enhance NHIF effectiveness, there is a need to revise the NHIF benefit package to include essential hypertension and/diabetes services, rev…
Factors associated with the availability and affordability of essential cardiovascular disease medicines in low- and middle-income countries
Despite their potential to prevent or delay the onset and progression of cardiovascular disease (CVD), medicines for CVD remain unavailable and unaffordable to many in low- and middle-income countries (LMICs). We systematically reviewed the literature to identify factors associated with availability and affordability of CVD medicines in LMICs. A protocol for this study was registered on the PROSPERO register of systematic reviews (CRD42019135393)…
Can we do for other essential medicines what we are doing for the Covid-19 vaccine
box By the beginning of 2021 the world welcomed encouraging news on several candidate vaccines for COVID-19. Pfizer-BioNTech, Moderna, Oxford/AstraZeneca and the Chinese BBIBP-CorV vaccines are already rolled out in some high-income countries, and other vaccines may follow. While in low-income and middle-income countries (LMICs) access is lagging, there are several vaccines with significant potential for fighting the pandemic in those LMICs that …
The household economic burden of non-communicable diseases in 18 countries
Background: Non-communicable diseases (NCDs) are the leading cause of death globally. In 2014, the United Nations committed to reducing premature mortality from NCDs, including by reducing the burden of healthcare costs. Since 2014, the Prospective Urban and Rural Epidemiology (PURE) Study has been collecting health expenditure data from households with NCDs in 18 countries. Methods: Using data from the PURE Study, we estimated risk of catastroph…
The economic burden of cardiovascular disease and hypertension in low- and middle-income countries
Persistent low adherence to hypertension treatment in Kyrgyzstan
It is well known that cardiovascular diseases (CVD) are a growing cause of mortality and morbidity in low-and middle-income countries (LMIC). While hypertension (HTN), a leading risk factor for CVD, can be easily managed with widely available medicines, there is a huge gap in treatment for HTN in many LMIC. One such country is Kyrgyzstan, where HTN is a major public health concern and adherence to medication is low. The reasons for low adherence …
One for all
Alcohol consumption is a leading cause of mortality and morbidity in countries of the former Soviet Union, but little is known about its social determinants. Recent research has suggested that workplace contexts may play a role. Using qualitative methods, we investigate the relationship between workplace social contexts and drinking in Ukraine. We conducted 24 individual semi-structured interviews and two focus group discussions in Lviv and Khark…
Using multi-level data to estimate the effect of an ‘alcogenic’ environment on hazardous alcohol consumption in the former Soviet Union
The economic burden of chronic disease care faced by households in Ukraine
The cost of chronic care in Ukraine places a burden on individual patient households. Households of angina patients are more likely to engage in distress financing to cover the cost of treatment, and a high proportion of patients do not acquire prescribed medicines because they cannot afford them. This warrants further research on the burden of NCD care in other LMIC, especially where OPP for health care is common. Health policies aimed at reduci…
Do citizens of the former Soviet Union trust state institutions, and why
This study examines trust in political institutions using data from surveys in nine former Soviet countries conducted in 2001 and in 2010/2011. Four hypotheses, micro and macro cultural and institutional, are tested. A measure of generalised trust in state institutions is compared across countries, alongside interpersonal trust, to examine the macro-theories. A multi-level analysis, using both individual variables from the survey, and aggregate v…
Estimating the causal effect of alcohol consumption on well-being for a cross-section of 9 former Soviet Union countries
Do citizens of the former Soviet Union trust state institutions, and why
This study examines trust in political institutions using data from surveys in nine former Soviet countries conducted in 2001 and in 2010/2011. Four hypotheses, micro and macro cultural and institutional, are tested. A measure of generalised trust in state institutions is compared across countries, alongside interpersonal trust, to examine the macro-theories. A multi-level analysis, using both individual variables from the survey, and aggregate v…
Persistent low adherence to hypertension treatment in Kyrgyzstan
It is well known that cardiovascular diseases (CVD) are a growing cause of mortality and morbidity in low-and middle-income countries (LMIC). While hypertension (HTN), a leading risk factor for CVD, can be easily managed with widely available medicines, there is a huge gap in treatment for HTN in many LMIC. One such country is Kyrgyzstan, where HTN is a major public health concern and adherence to medication is low. The reasons for low adherence …
Estimating the causal effect of alcohol consumption on well-being for a cross-section of 9 former Soviet Union countries
The economic burden of chronic disease care faced by households in Ukraine
The cost of chronic care in Ukraine places a burden on individual patient households. Households of angina patients are more likely to engage in distress financing to cover the cost of treatment, and a high proportion of patients do not acquire prescribed medicines because they cannot afford them. This warrants further research on the burden of NCD care in other LMIC, especially where OPP for health care is common. Health policies aimed at reduci…
Do citizens of the former Soviet Union trust state institutions, and why
This study examines trust in political institutions using data from surveys in nine former Soviet countries conducted in 2001 and in 2010/2011. Four hypotheses, micro and macro cultural and institutional, are tested. A measure of generalised trust in state institutions is compared across countries, alongside interpersonal trust, to examine the macro-theories. A multi-level analysis, using both individual variables from the survey, and aggregate v…
Estimating the causal effect of alcohol consumption on well-being for a cross-section of 9 former Soviet Union countries
One for all
Alcohol consumption is a leading cause of mortality and morbidity in countries of the former Soviet Union, but little is known about its social determinants. Recent research has suggested that workplace contexts may play a role. Using qualitative methods, we investigate the relationship between workplace social contexts and drinking in Ukraine. We conducted 24 individual semi-structured interviews and two focus group discussions in Lviv and Khark…
Using multi-level data to estimate the effect of an ‘alcogenic’ environment on hazardous alcohol consumption in the former Soviet Union
Persistent low adherence to hypertension treatment in Kyrgyzstan
It is well known that cardiovascular diseases (CVD) are a growing cause of mortality and morbidity in low-and middle-income countries (LMIC). While hypertension (HTN), a leading risk factor for CVD, can be easily managed with widely available medicines, there is a huge gap in treatment for HTN in many LMIC. One such country is Kyrgyzstan, where HTN is a major public health concern and adherence to medication is low. The reasons for low adherence …
The economic burden of cardiovascular disease and hypertension in low- and middle-income countries
The household economic burden of non-communicable diseases in 18 countries
Background: Non-communicable diseases (NCDs) are the leading cause of death globally. In 2014, the United Nations committed to reducing premature mortality from NCDs, including by reducing the burden of healthcare costs. Since 2014, the Prospective Urban and Rural Epidemiology (PURE) Study has been collecting health expenditure data from households with NCDs in 18 countries. Methods: Using data from the PURE Study, we estimated risk of catastroph…
Can we do for other essential medicines what we are doing for the Covid-19 vaccine
box By the beginning of 2021 the world welcomed encouraging news on several candidate vaccines for COVID-19. Pfizer-BioNTech, Moderna, Oxford/AstraZeneca and the Chinese BBIBP-CorV vaccines are already rolled out in some high-income countries, and other vaccines may follow. While in low-income and middle-income countries (LMICs) access is lagging, there are several vaccines with significant potential for fighting the pandemic in those LMICs that …
Factors associated with the availability and affordability of essential cardiovascular disease medicines in low- and middle-income countries
Despite their potential to prevent or delay the onset and progression of cardiovascular disease (CVD), medicines for CVD remain unavailable and unaffordable to many in low- and middle-income countries (LMICs). We systematically reviewed the literature to identify factors associated with availability and affordability of CVD medicines in LMICs. A protocol for this study was registered on the PROSPERO register of systematic reviews (CRD42019135393)…
Comparing estimates of household expenditures between pictorial diaries and surveys in three low- and middle-income countries
In most low- and middle-income countries (LMICs), household out-of-pocket (OOP) health spending constitutes a major source of healthcare financing. Household surveys are commonly used to monitor OOP health spending, but are prone to recall bias and unable to capture seasonal variation, and may underestimate expenditure–particularly among households with long-term chronic health conditions. Household expenditure diaries have been developed as an a…
Understanding the treatment burden of people with chronic conditions in Kenya
In Kenya, non-communicable diseases (NCDs) are an increasingly important cause of morbidity and mortality, requiring both better access to health care services and self-care support. Evidence suggests that treatment burdens can negatively affect adherence to treatment and quality of life. In this study, we explored the treatment and self-management burden among people with NCDs in in two counties in Western Kenya. We conducted a cross-sectional s…
Evaluating the effectiveness of the National Health Insurance Fund in providing financial protection to households with hypertension and diabetes patients in Kenya
We did not find strong evidence that the NHIF national scheme is effective in providing financial risk protection to households with individuals living with hypertension and/diabetes in Kenya. This could partly be explained by the low depth of cover of the NHIF national scheme, and the high attrition rate. To enhance NHIF effectiveness, there is a need to revise the NHIF benefit package to include essential hypertension and/diabetes services, rev…
Managing diabetes and hypertension in western Kenya
The Primary Health Integrated Care for Chronic Conditions (PIC4C) pilot project was launched in 2018 to strengthen prevention and control of four non-communicable conditions at primary health care level in western Kenya. We conducted a qualitative study to explore the extent to which PIC4C integrated services supported people with hypertension and/or diabetes towards timely diagnosis and referral, treatment, follow-up and adherence, from the pers…
‘You can sleep hungry just to buy the medicine’
This research applies the Cumulative Complexity model to examine patient experiences of hypertension management following prescription of anti-hypertensive medication in the public health system in Kenya. Set in Kiambu County, central Kenya, it draws on abductive analysis of interviews with patients (n = 24), caregivers (n = 7) and non-participant observation in four purposively selected public facilities conducted between November 2022 and April…
Implementation strategies to improve outcomes in patients with established cardiovascular disease in sub-Saharan Africa
Sub-Saharan Africa (SSA) is experiencing an epidemic of cardiovascular disease (CVD). Despite numerous evidence-based therapies and management guidelines for patients with acute or established CVD, significant gaps persist in their implementation in SSA. This systematic review aims to describe, synthesise and identify key gaps in the implementation strategies of evidence-based approaches that can improve clinical outcomes for patients with acute …
Acceptability of fixed-dose combination treatments for hypertension in Kenya
Fixed-dose combinations (FDCs) – 2-3 anti-hypertensive medications in a single pill - have the potential to improve hypertension treatment and outcomes. Yet, they are not widely implemented. Factors undermining implementation remain unknown, particularly in sub–Saharan Africa, where hypertension is a major cause of disease burden and is poorly controlled. This study explored the acceptability of FDCs among patients, caregivers, and healthcare wor…
Medicine (12 obras) · Environmental health (8 obras) · Economic growth (6 obras) · Economics (6 obras) · Health care (6 obras) · Healthcare Systems and Reforms (6 obras) · Political science (6 obras) · Global Health Care Issues (5 obras) · Psychology (5 obras) · Business (4 obras)