Ida Malkin
Dados Biográficos
| ID | 4048680 |
|---|---|
| NOME | Ida Malkin |
| PRENOMES | Ida |
| SOBRENOME | Malkin |
| ASSINATURA | MALKIN I |
| AFILIAÇÕES | Tel Aviv University |
| VERIFICADO | Não |
| TOTAL DE OBRAS | 19 |
| TOTAL DE CITAÇÕES | 7 |
| TOTAL COMO AUTOR | 19 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2001 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2012 |
| ÍNDICE H | 1 |
Inheritance of dermatoglyphic traits in twins
Dermatoglyphic traits in a sample of twins were analyzed to estimate the resemblance between MZ and DZ twins and to evaluate the mode of inheritance by using the maximum likelihood-based Variance decomposition analysis. The additive genetic variance component was significant in both sexes for four traits--PII, AB_RC, RC_HB, and ATD_L. AB RC and RC_HB had significant sex differences in means, whereas PII and ATD_L did not. The results of the Bivar…
Inheritance of finger pattern types in MZ and DZ twins
Inheritance of 18 quantitative dermatoglyphic traits based on Factors in MZ and DZ twins
18 quantitative finger and palmar dermatoglyphic traits were analyzed with the aim of determining genetic effects and common familial environmental influences on a large (358 nuclear pedigrees) number of twins (MZ and DZ). Genetic analysis based on principal factors includes variance and bivariate variance decomposition analysis. Especially, Factor 1 (digital pattern size) is remarkable, due to its degree of universality. The results of genetic a…
Climatic factors in the development of radiographic hand osteoarthritis
Family-based study of association between ENPP1 genetic variants and craniofacial morphology
The findings obtained in this study suggest that the upstream, promoter and 3' untranslated regions in the ENPP1 locus harbor genetic variants affecting different aspects of craniofacial morphology. Further research is required to validate the relevancy of the potentially functional ENPP1 regions to normal and pathologic craniofacial growth
Genetic Determinants of 22 Quantitative Dermatoglyphic Traits in the Chuvashian Population of Russia
Background: Dermatoglyphics is widely used as a genetically determined trait in Anthropology.However, little is known about their pattern of inheritance due to lack of advanced statistical genetic model-fitting techniques despite the existence of advanced statistical packages. Objectives:The aim of the present study is to determine the mode of inheritance of dermatoglyphic traits through complex segregation analysis.Subjects and Methods: Finger a…
Age-related changes and secular trends in hand bone size
Anthropometric and bone-related biochemical factors are associated with different haplotypes of ANKH locus
Taken together, the results show discrimination between the corresponding regions and haplotypes, suggesting trait-specific gene variants that influenced bone-related phenotypic variation in the studied population
Genetic and environmental determinants of hepatocyte growth factor levels and their association with obesity and blood pressure
The results provide evidence that putative genetic factors involved in regulation of HGF variation contribute also significantly to variation of the obesity and BP. It is possible that the familial resemblance for WHR and the SBP correlation in the studied sample is affected substantially by genetic factors regulating circulating HGF levels
Secular Trends of Reproductive Indices in Chuvashian Women
In the present cross-sectional study of the Chuvashian rural population, we examined the secular trends of age at menarche, the age at menopause, the reproductive period, and the age of the first marriage of Chuvashian women. The cohort included 745 women aged 18–90 years; age at menarche (N = 653) ranging from 10 to 24 years (mean 15.42 ± 2.11). Data regarding menopausal age was obtained from 316 women born between 1920 and 1950 (mean 48.5 ± 4.6…
Search for Hand Osteoarthritis Susceptibility Locus on Chromosome 6p12.3-p12.1
The existence of osteoarthritis susceptibility loci on chromosome 6 for individuals suffering from hip and knee osteoarthritis has been suggested. We determined whether radiographic hand osteoarthritis in a demographically homogeneous population of European origin can be linked to loci on chromosome 6p12.3-p12.1. Nine single nucleotide polymorphisms (SNPs) were genotyped in 764 individuals (members of 189 nuclear and more complex two- or three-ge…
Variation of skeletal biomarkers of biological aging in a Chuvashian population
Osseographic score (OSS) is a skeletal biomarker of biological aging, based on assessment of the hand's radiographic features. The aims of the present cross-sectional and follow-up study were: 1) to evaluate age-related changes of OSS in a large Chuvashian cohort, and 2) to evaluate sex differences in age-related changes of OSS. This study reports on intersexual differences in the pattern of skeletal aging. The most prominent difference was in th…
Age at menarche in a Chuvashian rural population
Our study demonstrated the certain secular trends of age at menarche in Chuvashian women who matured after World War II. Periods of socio-economic disasters such as war and famine disrupt the secular trend. Our findings also confirm the hypothesis of significant familial influences on menarcheal age
Association between physique characteristics and hand skeletal aging status
The aim of the present study was to evaluate the association between skeletal aging traits (obtained from evaluation of hand radiographs) and physique characteristics, including indices of obesity, skeletal size, muscular development, and the somatotypes of Heath and Carter (1967) and of Deriabin (1985). To achieve our aims, we used multiple regression analysis, and Pearson's and canonical correlation analyses. The studied population comprised 62…
Israeli Jewish infants of different descent
BACKGROUND: Due to increasing migration process and intermarriages among individuals belonging to different ethnic groups, it is important to examine whether intermixing of populations effects child growth rate. AIMS: To compare growth patterns of Jewish infants from distinct descent. SUBJECTS: 1300 Israeli children were divided into 7 groups: 4 groups of babies with both parents from the same geographic origin (Europe, Yemen, Middle East or Nort…
Modelling of age-related bone loss using cross-sectional data
The change of phalangeal BMD with age may be best described by a two-interval function, regardless of sex and ethnic background. However, specific parameter estimates depend both on gender and ethnic affiliation. This study has yielded a well-fitted model of BMD dependence on age suitable for further use in population studies
Evidence on major gene control of cortical index in pedigree data from middle dalmatia, croatia
Evidence on major gene control of cortical index in pedigree data from Middle Dalmatia, Croatia
It was recently reported that the inheritance of the metacarpal cortical index (CI) in the Chuvashian population can be described in terms of a major gene (MG) model. By applying transmission probability tests, the hypothesis was accepted that not only baseline level of CI but also its sex-specific dependence on age were under control of the same putative large-effect gene. Using a pedigree sample from the population of the islands of Middle Dalm…
Evidence on major gene control of cortical index in pedigree data from Middle Dalmatia, Croatia
It was recently reported that the inheritance of the metacarpal cortical index (CI) in the Chuvashian population can be described in terms of a major gene (MG) model. By applying transmission probability tests, the hypothesis was accepted that not only baseline level of CI but also its sex-specific dependence on age were under control of the same putative large-effect gene. Using a pedigree sample from the population of the islands of Middle Dalm…
Secular Trends of Reproductive Indices in Chuvashian Women
In the present cross-sectional study of the Chuvashian rural population, we examined the secular trends of age at menarche, the age at menopause, the reproductive period, and the age of the first marriage of Chuvashian women. The cohort included 745 women aged 18–90 years; age at menarche (N = 653) ranging from 10 to 24 years (mean 15.42 ± 2.11). Data regarding menopausal age was obtained from 316 women born between 1920 and 1950 (mean 48.5 ± 4.6…
Association between physique characteristics and hand skeletal aging status
The aim of the present study was to evaluate the association between skeletal aging traits (obtained from evaluation of hand radiographs) and physique characteristics, including indices of obesity, skeletal size, muscular development, and the somatotypes of Heath and Carter (1967) and of Deriabin (1985). To achieve our aims, we used multiple regression analysis, and Pearson's and canonical correlation analyses. The studied population comprised 62…
Evidence on major gene control of cortical index in pedigree data from middle dalmatia, croatia
Evidence on major gene control of cortical index in pedigree data from Middle Dalmatia, Croatia
It was recently reported that the inheritance of the metacarpal cortical index (CI) in the Chuvashian population can be described in terms of a major gene (MG) model. By applying transmission probability tests, the hypothesis was accepted that not only baseline level of CI but also its sex-specific dependence on age were under control of the same putative large-effect gene. Using a pedigree sample from the population of the islands of Middle Dalm…
Evidence on major gene control of cortical index in pedigree data from Middle Dalmatia, Croatia
It was recently reported that the inheritance of the metacarpal cortical index (CI) in the Chuvashian population can be described in terms of a major gene (MG) model. By applying transmission probability tests, the hypothesis was accepted that not only baseline level of CI but also its sex-specific dependence on age were under control of the same putative large-effect gene. Using a pedigree sample from the population of the islands of Middle Dalm…
Modelling of age-related bone loss using cross-sectional data
The change of phalangeal BMD with age may be best described by a two-interval function, regardless of sex and ethnic background. However, specific parameter estimates depend both on gender and ethnic affiliation. This study has yielded a well-fitted model of BMD dependence on age suitable for further use in population studies
Israeli Jewish infants of different descent
BACKGROUND: Due to increasing migration process and intermarriages among individuals belonging to different ethnic groups, it is important to examine whether intermixing of populations effects child growth rate. AIMS: To compare growth patterns of Jewish infants from distinct descent. SUBJECTS: 1300 Israeli children were divided into 7 groups: 4 groups of babies with both parents from the same geographic origin (Europe, Yemen, Middle East or Nort…
Association between physique characteristics and hand skeletal aging status
The aim of the present study was to evaluate the association between skeletal aging traits (obtained from evaluation of hand radiographs) and physique characteristics, including indices of obesity, skeletal size, muscular development, and the somatotypes of Heath and Carter (1967) and of Deriabin (1985). To achieve our aims, we used multiple regression analysis, and Pearson's and canonical correlation analyses. The studied population comprised 62…
Variation of skeletal biomarkers of biological aging in a Chuvashian population
Osseographic score (OSS) is a skeletal biomarker of biological aging, based on assessment of the hand's radiographic features. The aims of the present cross-sectional and follow-up study were: 1) to evaluate age-related changes of OSS in a large Chuvashian cohort, and 2) to evaluate sex differences in age-related changes of OSS. This study reports on intersexual differences in the pattern of skeletal aging. The most prominent difference was in th…
Age at menarche in a Chuvashian rural population
Our study demonstrated the certain secular trends of age at menarche in Chuvashian women who matured after World War II. Periods of socio-economic disasters such as war and famine disrupt the secular trend. Our findings also confirm the hypothesis of significant familial influences on menarcheal age
Secular Trends of Reproductive Indices in Chuvashian Women
In the present cross-sectional study of the Chuvashian rural population, we examined the secular trends of age at menarche, the age at menopause, the reproductive period, and the age of the first marriage of Chuvashian women. The cohort included 745 women aged 18–90 years; age at menarche (N = 653) ranging from 10 to 24 years (mean 15.42 ± 2.11). Data regarding menopausal age was obtained from 316 women born between 1920 and 1950 (mean 48.5 ± 4.6…
Search for Hand Osteoarthritis Susceptibility Locus on Chromosome 6p12.3-p12.1
The existence of osteoarthritis susceptibility loci on chromosome 6 for individuals suffering from hip and knee osteoarthritis has been suggested. We determined whether radiographic hand osteoarthritis in a demographically homogeneous population of European origin can be linked to loci on chromosome 6p12.3-p12.1. Nine single nucleotide polymorphisms (SNPs) were genotyped in 764 individuals (members of 189 nuclear and more complex two- or three-ge…
Age-related changes and secular trends in hand bone size
Anthropometric and bone-related biochemical factors are associated with different haplotypes of ANKH locus
Taken together, the results show discrimination between the corresponding regions and haplotypes, suggesting trait-specific gene variants that influenced bone-related phenotypic variation in the studied population
Genetic and environmental determinants of hepatocyte growth factor levels and their association with obesity and blood pressure
The results provide evidence that putative genetic factors involved in regulation of HGF variation contribute also significantly to variation of the obesity and BP. It is possible that the familial resemblance for WHR and the SBP correlation in the studied sample is affected substantially by genetic factors regulating circulating HGF levels
Genetic Determinants of 22 Quantitative Dermatoglyphic Traits in the Chuvashian Population of Russia
Background: Dermatoglyphics is widely used as a genetically determined trait in Anthropology.However, little is known about their pattern of inheritance due to lack of advanced statistical genetic model-fitting techniques despite the existence of advanced statistical packages. Objectives:The aim of the present study is to determine the mode of inheritance of dermatoglyphic traits through complex segregation analysis.Subjects and Methods: Finger a…
Climatic factors in the development of radiographic hand osteoarthritis
Family-based study of association between ENPP1 genetic variants and craniofacial morphology
The findings obtained in this study suggest that the upstream, promoter and 3' untranslated regions in the ENPP1 locus harbor genetic variants affecting different aspects of craniofacial morphology. Further research is required to validate the relevancy of the potentially functional ENPP1 regions to normal and pathologic craniofacial growth
Inheritance of finger pattern types in MZ and DZ twins
Inheritance of 18 quantitative dermatoglyphic traits based on Factors in MZ and DZ twins
18 quantitative finger and palmar dermatoglyphic traits were analyzed with the aim of determining genetic effects and common familial environmental influences on a large (358 nuclear pedigrees) number of twins (MZ and DZ). Genetic analysis based on principal factors includes variance and bivariate variance decomposition analysis. Especially, Factor 1 (digital pattern size) is remarkable, due to its degree of universality. The results of genetic a…
Inheritance of dermatoglyphic traits in twins
Dermatoglyphic traits in a sample of twins were analyzed to estimate the resemblance between MZ and DZ twins and to evaluate the mode of inheritance by using the maximum likelihood-based Variance decomposition analysis. The additive genetic variance component was significant in both sexes for four traits--PII, AB_RC, RC_HB, and ATD_L. AB RC and RC_HB had significant sex differences in means, whereas PII and ATD_L did not. The results of the Bivar…
Biology (12 obras) · Demography (11 obras) · Medicine (10 obras) · Population (9 obras) · Genetics (8 obras) · Gene (7 obras) · Internal Medicine (6 obras) · Statistics (6 obras) · Bone health and osteoporosis research (5 obras) · Mathematics (5 obras)