Sena Karachanak-Yankova
Dados Biográficos
| ID | 4090958 |
|---|---|
| NOME | Sena Karachanak-Yankova |
| PRENOMES | Sena |
| SOBRENOME | Karachanak-Yankova |
| ASSINATURA | KARACHANAK-YANKOVA S |
| AFILIAÇÕES | Medical University of Sofia |
| ORCID | 0000-0001-6441-629X |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 7 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 7 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2014 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2023 |
| ÍNDICE H | 0 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Susceptibility to Neurodegenerative Disorders
Ancient human genome data accumulated in recent years can be employed to establish the spatiotemporal trajectories of genetic variants associated with human diseases. Such knowledge might illuminate if and how past adaptations impact contemporary human health and medicine. Scarcely any studies have yet attempted to evaluate genetic susceptibility to neurodegenerative disorders in ancient human communities. Using publicly available ancient human g…
The Uniparental Genetic Landscape of Modern Slavic Speaking Populations
Slavic speaking populations are the most numerous Indo-European ethnolinguistic group in Europe. They show great variety and fall into three groups: West, East and South Slavic populations. In order to contribute to the understanding of the correlation between linguistic and genetic affiliation of Slavic populations, we have analyzed for the first time their matrilineal and patrilineal relationships and we have also illustrated their position in …
The Simons Genome Diversity Project
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergenc…
Distribution of East Eurasian Y-Chromosome and Mitochondrial DNA Haplogroups across Eurasia
The modern Bulgarian mitochondrial DNA (mtDNA) and Y-chromosome gene pools predominantly consist of Western Eurasian haplogroups. In contrast, the Eastern Eurasian lineages are found at very low frequencies in Bulgarians, being represented only by mtDNA haplogroups C (0.2%), D (0.4%) and Z (0.1%) (Karachanak et al., 2012) and Y-chromosome haplogroups C, N and Q (each 0.5%) (Karachanak et al., 2013). A similar pattern is observed in ancient mtDNA …
Mitochondrial DNA Suggests a Western Eurasian Origin for Ancient (Proto-) Bulgarians
Ancient (proto-) Bulgarians have long been thought of as a Turkic population. However, evidence found in the past three decades shows that this is not the case. Until now, this evidence has not included ancient mitochondrial DNA (mtDNA) analysis. To fill this void, we collected human remains from the 8th to the 10th century AD located in three necropolises in Bulgaria: Nojarevo (Silistra region) and Monastery of Mostich (Shumen region), both in n…
Ancient human genomes suggest three ancestral populations for present-day Europeans
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Ancient human genomes suggest three ancestral populations for present-day Europeans
Distribution of East Eurasian Y-Chromosome and Mitochondrial DNA Haplogroups across Eurasia
The modern Bulgarian mitochondrial DNA (mtDNA) and Y-chromosome gene pools predominantly consist of Western Eurasian haplogroups. In contrast, the Eastern Eurasian lineages are found at very low frequencies in Bulgarians, being represented only by mtDNA haplogroups C (0.2%), D (0.4%) and Z (0.1%) (Karachanak et al., 2012) and Y-chromosome haplogroups C, N and Q (each 0.5%) (Karachanak et al., 2013). A similar pattern is observed in ancient mtDNA …
Mitochondrial DNA Suggests a Western Eurasian Origin for Ancient (Proto-) Bulgarians
Ancient (proto-) Bulgarians have long been thought of as a Turkic population. However, evidence found in the past three decades shows that this is not the case. Until now, this evidence has not included ancient mitochondrial DNA (mtDNA) analysis. To fill this void, we collected human remains from the 8th to the 10th century AD located in three necropolises in Bulgaria: Nojarevo (Silistra region) and Monastery of Mostich (Shumen region), both in n…
The Simons Genome Diversity Project
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergenc…
The Uniparental Genetic Landscape of Modern Slavic Speaking Populations
Slavic speaking populations are the most numerous Indo-European ethnolinguistic group in Europe. They show great variety and fall into three groups: West, East and South Slavic populations. In order to contribute to the understanding of the correlation between linguistic and genetic affiliation of Slavic populations, we have analyzed for the first time their matrilineal and patrilineal relationships and we have also illustrated their position in …
Susceptibility to Neurodegenerative Disorders
Ancient human genome data accumulated in recent years can be employed to establish the spatiotemporal trajectories of genetic variants associated with human diseases. Such knowledge might illuminate if and how past adaptations impact contemporary human health and medicine. Scarcely any studies have yet attempted to evaluate genetic susceptibility to neurodegenerative disorders in ancient human communities. Using publicly available ancient human g…
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Biology (7 obras) · Evolutionary biology (6 obras) · Gene (6 obras) · Forensic and Genetic Research (5 obras) · Genetics (5 obras) · Geography (5 obras) · Population (5 obras) · Demography (4 obras) · Genetics (4 obras) · Genome (4 obras)