Charles L Greenblatt
Dados Biográficos
| ID | 4308293 |
|---|---|
| NOME | Charles L Greenblatt |
| PRENOMES | Charles L |
| SOBRENOME | Greenblatt |
| ASSINATURA | GREENBLATT C L |
| AFILIAÇÕES | Department of Parasitology Hebrew University-Hadassah Medical School Kuvin Centre for the Study of Infectious and Tropical Diseases Jerusalem, Israel |
| ORCID | 0000-0001-7118-0238 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 8 |
| TOTAL DE CITAÇÕES | 38 |
| TOTAL COMO AUTOR | 5 |
| TOTAL COMO EDITOR | 3 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1998 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2009 |
| ÍNDICE H | 2 |
Biomolecular archaeology of ancient tuberculosis
Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean
BACKGROUND: Mycobacterium tuberculosis is the principal etiologic agent of human tuberculosis. It has no environmental reservoir and is believed to have co-evolved with its host over millennia. This is supported by skeletal evidence of the disease in early humans, and inferred from M. tuberculosis genomic analysis. Direct examination of ancient human remains for M. tuberculosis biomarkers should aid our understanding of the nature of prehistoric …
Title Pages
An overview
When professionals are in panic, the layman has every right to be concerned. The events of September 11th 2001, followed by the successful use of the anthrax bacillus as a weapon of bio terrorism struck fear into the hearts of many, including the public health professionals to whom we entrust our care. Those dramatic events can be seen against a background of a general dispair concerning the capabilities of physicians to handle infectious disease…
Lessons from the past
In two universities I attempted to obtain biosafety guidelines for the culture of amber. The answers, not committed to writing were, ‘These are ordinary environmental microbes, and women have been rubbing their amber beads on their chests for years.’ But still the fears persist. In Italy, when I attempted to culture bones from Pompeii, one student simply freaked out. A question to Jeff Taubenberger: I know that the ‘American expedition’ that exhu…
Emerging Pathogens
Many ancient diseases with a long history of afflicting mankind such as Tuberculosis and Malaria are now re-emerging. Greenblatt brings together palaeopathologists, anthropologists, molecular biologists and modern infectious disease specialists to examine this phenomenon. New techniques allow us to detect ancient pathogen DNA and other biomarkers, in effect the chemical ‘signatures’ of pathogens. These tools could help us develop strategies to co…
Confirmation of the presence of Mycobacterium tuberculosis complex-specific DNA in three archaeological specimens
This journal published the first reported identification of Mycobacterium tuberculosis complex (MTB) DNA in ancient human remains but concerns were raised about the article two years after publication. These were based on methodology which, in the field of ancient DNA, was still developing. Here we present a re-examination of the 1993 research conducted on three specimens which exhibited palaeopathologies indicative of tuberculosis. The specimens…
Determining the Sex of Infanticide Victims from the Late Roman Era through Ancient DNA Analysis
Determining the Sex of Infanticide Victims from the Late Roman Era through Ancient DNA Analysis
Biomolecular archaeology of ancient tuberculosis
Confirmation of the presence of Mycobacterium tuberculosis complex-specific DNA in three archaeological specimens
This journal published the first reported identification of Mycobacterium tuberculosis complex (MTB) DNA in ancient human remains but concerns were raised about the article two years after publication. These were based on methodology which, in the field of ancient DNA, was still developing. Here we present a re-examination of the 1993 research conducted on three specimens which exhibited palaeopathologies indicative of tuberculosis. The specimens…
Determining the Sex of Infanticide Victims from the Late Roman Era through Ancient DNA Analysis
Confirmation of the presence of Mycobacterium tuberculosis complex-specific DNA in three archaeological specimens
This journal published the first reported identification of Mycobacterium tuberculosis complex (MTB) DNA in ancient human remains but concerns were raised about the article two years after publication. These were based on methodology which, in the field of ancient DNA, was still developing. Here we present a re-examination of the 1993 research conducted on three specimens which exhibited palaeopathologies indicative of tuberculosis. The specimens…
Title Pages
An overview
When professionals are in panic, the layman has every right to be concerned. The events of September 11th 2001, followed by the successful use of the anthrax bacillus as a weapon of bio terrorism struck fear into the hearts of many, including the public health professionals to whom we entrust our care. Those dramatic events can be seen against a background of a general dispair concerning the capabilities of physicians to handle infectious disease…
Lessons from the past
In two universities I attempted to obtain biosafety guidelines for the culture of amber. The answers, not committed to writing were, ‘These are ordinary environmental microbes, and women have been rubbing their amber beads on their chests for years.’ But still the fears persist. In Italy, when I attempted to culture bones from Pompeii, one student simply freaked out. A question to Jeff Taubenberger: I know that the ‘American expedition’ that exhu…
Emerging Pathogens
Many ancient diseases with a long history of afflicting mankind such as Tuberculosis and Malaria are now re-emerging. Greenblatt brings together palaeopathologists, anthropologists, molecular biologists and modern infectious disease specialists to examine this phenomenon. New techniques allow us to detect ancient pathogen DNA and other biomarkers, in effect the chemical ‘signatures’ of pathogens. These tools could help us develop strategies to co…
Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean
BACKGROUND: Mycobacterium tuberculosis is the principal etiologic agent of human tuberculosis. It has no environmental reservoir and is believed to have co-evolved with its host over millennia. This is supported by skeletal evidence of the disease in early humans, and inferred from M. tuberculosis genomic analysis. Direct examination of ancient human remains for M. tuberculosis biomarkers should aid our understanding of the nature of prehistoric …
Biomolecular archaeology of ancient tuberculosis
Biology (5 obras) · History (5 obras) · Medicine (5 obras) · Pathology (5 obras) · Ancient DNA (4 obras) · Archaeology (4 obras) · Tuberculosis (4 obras) · Law (3 obras) · Political science (3 obras) · Tuberculosis Research and Epidemiology (3 obras)