Ayesha B M Kharsany
Dados Biográficos
| ID | 4889029 |
|---|---|
| NOME | Ayesha B M Kharsany |
| PRENOMES | Ayesha B M |
| SOBRENOME | Kharsany |
| ASSINATURA | KHARSANY A B M |
| AFILIAÇÕES | Centre for the AIDS Programme of Research in South Africa |
| ORCID | 0000-0001-7457-0194 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 18 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 18 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2010 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 0 |
Syndemic mapping of HIV and other STIs in KwaZulu-Natal
Syndemics involving Human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs) remain a major public health challenge in sub-Saharan Africa, and understanding their spatial and temporal dynamics is critical for effective interventions. Using data from two consecutive, population-based cross-sectional surveys conducted in 2014 and 2015 under the HIV Incidence Provincial Surveillance System (HIPSS) in KwaZulu-Natal, South A…
Spatial Analysis of HIV Determinants Among Females Aged 15–34 in KwaZulu Natal, South Africa
HIV remains a major public health challenge in sub-Saharan Africa, with South Africa bearing the highest burden. This study confirms that KwaZulu-Natal (KZN) is a hotspot, with a high HIV prevalence of 47.4% (95% CI: 45.7-49.1) among females aged 15-34. We investigated the spatial distribution and key socio-demographic, behavioural, and economic factors associated with HIV prevalence in this group using a Bayesian spatial logistic regression mode…
Exposure to comprehensive sexuality education in schools in South Africa
Comprehensive sexuality education (CSE) is seen as a key instrument through which to affect behaviour and improve sexual and reproductive health (SRH) outcomes amongst adolescents. However, few studies have to date evaluated key SRH outcomes following exposure to CSE within a school setting. This study estimates the association between CSE and HIV testing and HIV testing self-efficacy amongst HIV positive adolescent girls. Data were collected fro…
Determining HIV risk for Adolescent Girls and Young Women (Agyw) in relationships with “Blessers” and age-disparate partners
Different relationships present different HIV risk to AGYW. AGYW who had engaged in relationships with both a Blesser and an age-disparate partner were at greater HIV risk when examined against these relationships independent of one another. The data reveals the compounded HIV risk of being in both a transactional and age-disparate relationship
Depression symptoms, HIV testing, linkage to ART, and viral suppression among women in a high HIV burden district in KwaZulu-Natal, South Africa
Achieving the UNAIDS 90-90-90 targets by 2020 is contingent on identifying and addressing mental health challenges that may affect HIV testing and treatment-related behaviors. This study is based on survey data from KwaZulu-Natal, South Africa (2014-2015). HIV positive women who reported higher depression scores had a lower odds of having tested previously for HIV (15-25 years: AOR = 0.90, 95% CI [0.83, 0.98]; 26-49 years: AOR = 0.90, 95% CI [0.8…
Poor rates of linkage to HIV care and uptake of treatment after home-based HIV testing among newly diagnosed 15-to-49 year-old men and women in a high HIV prevalence setting in South Africa
Early antiretroviral therapy (ART) initiation is essential, but linkage to care following community-based services is often poor, and inadequately understood. This study examined factors influencing linkage to care following home-based HIV-testing services (HBHTS) in a hyper-endemic setting in South Africa. HBHTS was offered to participants (N = 10,236) enrolled in the second HIV Incidence Provincial Surveillance System survey (2015–2016), KwaZul…
Association of medical male circumcision and sexually transmitted infections in a population-based study using targeted maximum likelihood estimation
Using a TMLE approach, we present further evidence of a protective association of MMC against HIV and HSV-2 in this hyper-endemic South African setting. TMLE has the potential to enhance the evidence base for recommendations that embrace the effect of public health interventions on health or disease outcomes
Prevalence and Risk Factors for HIV Infection Among Heterosexual Men Recruited from Socializing Venues in Rural KwaZulu-Natal, South Africa
Perceived HIV-related stigma among university students in South Africa
HIV-related stigma, and particularly perceived stigma, has a negative impact across the HIV care continuum. This study adds to our understanding of stigma by assessing how perceived stigma varies from one context to another and how such differences are associated with the location where individuals would prefer an HIV test. We used self-administered questionnaire data (n = 378) obtained from a convenience sample of students (18 years and older) a…
HIV Infection and Aids in Sub-Saharan Africa
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and substantial declines in AIDS related deaths largely attributable to the survival benefits of antiretroviral treatment. Sub-Saharan Africa carries a disproportionate burden of HIV, accounting for more than 70% of the global burden of infection. Success in HIV prevention in sub-Saharan Africa has the potential to impact on the global burden of HIV. Notwithstanding …
Strengthening HIV surveillance
Surveillance for HIV as a public health initiative requires timely, detailed and robust data to systematically understand burden of infection, transmission patterns, direct prevention efforts, guide funding, identify new infections and predict future trends in the epidemic. The methods for HIV surveillance have evolved to reliably track the epidemic and identify new infections in real time. Initially HIV surveillance relied primarily on the repor…
Strengthening HIV surveillance in the antiretroviral therapy era
The results from HIPSS will provide critical data regarding HIV prevalence and incidence in this community and will establish whether HIV prevention and treatment efforts in a "real world", non-trial setting have an impact on HIV incidence at a population level. Importantly, the study design and methods will inform future methods for HIV surveillance
Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting
HIV-Positive Status Disclosure in Patients in Care in Rural South Africa
HIV prevalence among high school learners - opportunities for schools-based HIV testing programmes and sexual reproductive health services
The high HIV prevalence in female learners underscores the importance of sexual reproductive health and schools-based HIV testing programs as an important gateway to prevention and treatment services
HIV Incidence in Young Girls in KwaZulu-Natal, South Africa-Public Health Imperative for Their Inclusion in HIV Biomedical Intervention Trials
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Vaginal Gel Versus HIV HIV prevention technologies for women are urgently needed, especially in sub-Saharan Africa where young women bear the greatest burden of the HIV epidemic. Abdool Karim et al. (p. 1168 ; published online 19 July) present the results of the CAPRISA 004 randomized control trial. The nearly 3-year-long trial, conducted in urban and rural South African women, tested the efficacy of a vaginal gel containing the antiretroviral dr…
Uptake of provider-initiated HIV testing and counseling among women attending an urban sexually transmitted disease clinic in South Africa – missed opportunities for early diagnosis of HIV infection
This study assessed the uptake of provider-initiated HIV testing and counseling (PITC) among women attending an urban sexually transmitted diseases (STD) clinic in South Africa. From July 2005 to June 2006, women were offered HIV testing following group information and education on HIV and STDs in the clinic waiting area. Of those who were provided with education, information, and offered HIV testing, uptake was 43.5% (2439/5612). The overall HIV…
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Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Vaginal Gel Versus HIV HIV prevention technologies for women are urgently needed, especially in sub-Saharan Africa where young women bear the greatest burden of the HIV epidemic. Abdool Karim et al. (p. 1168 ; published online 19 July) present the results of the CAPRISA 004 randomized control trial. The nearly 3-year-long trial, conducted in urban and rural South African women, tested the efficacy of a vaginal gel containing the antiretroviral dr…
Uptake of provider-initiated HIV testing and counseling among women attending an urban sexually transmitted disease clinic in South Africa – missed opportunities for early diagnosis of HIV infection
This study assessed the uptake of provider-initiated HIV testing and counseling (PITC) among women attending an urban sexually transmitted diseases (STD) clinic in South Africa. From July 2005 to June 2006, women were offered HIV testing following group information and education on HIV and STDs in the clinic waiting area. Of those who were provided with education, information, and offered HIV testing, uptake was 43.5% (2439/5612). The overall HIV…
HIV prevalence among high school learners - opportunities for schools-based HIV testing programmes and sexual reproductive health services
The high HIV prevalence in female learners underscores the importance of sexual reproductive health and schools-based HIV testing programs as an important gateway to prevention and treatment services
HIV Incidence in Young Girls in KwaZulu-Natal, South Africa-Public Health Imperative for Their Inclusion in HIV Biomedical Intervention Trials
Strengthening HIV surveillance in the antiretroviral therapy era
The results from HIPSS will provide critical data regarding HIV prevalence and incidence in this community and will establish whether HIV prevention and treatment efforts in a "real world", non-trial setting have an impact on HIV incidence at a population level. Importantly, the study design and methods will inform future methods for HIV surveillance
Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting
HIV-Positive Status Disclosure in Patients in Care in Rural South Africa
HIV Infection and Aids in Sub-Saharan Africa
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and substantial declines in AIDS related deaths largely attributable to the survival benefits of antiretroviral treatment. Sub-Saharan Africa carries a disproportionate burden of HIV, accounting for more than 70% of the global burden of infection. Success in HIV prevention in sub-Saharan Africa has the potential to impact on the global burden of HIV. Notwithstanding …
Strengthening HIV surveillance
Surveillance for HIV as a public health initiative requires timely, detailed and robust data to systematically understand burden of infection, transmission patterns, direct prevention efforts, guide funding, identify new infections and predict future trends in the epidemic. The methods for HIV surveillance have evolved to reliably track the epidemic and identify new infections in real time. Initially HIV surveillance relied primarily on the repor…
Perceived HIV-related stigma among university students in South Africa
HIV-related stigma, and particularly perceived stigma, has a negative impact across the HIV care continuum. This study adds to our understanding of stigma by assessing how perceived stigma varies from one context to another and how such differences are associated with the location where individuals would prefer an HIV test. We used self-administered questionnaire data (n = 378) obtained from a convenience sample of students (18 years and older) a…
Poor rates of linkage to HIV care and uptake of treatment after home-based HIV testing among newly diagnosed 15-to-49 year-old men and women in a high HIV prevalence setting in South Africa
Early antiretroviral therapy (ART) initiation is essential, but linkage to care following community-based services is often poor, and inadequately understood. This study examined factors influencing linkage to care following home-based HIV-testing services (HBHTS) in a hyper-endemic setting in South Africa. HBHTS was offered to participants (N = 10,236) enrolled in the second HIV Incidence Provincial Surveillance System survey (2015–2016), KwaZul…
Association of medical male circumcision and sexually transmitted infections in a population-based study using targeted maximum likelihood estimation
Using a TMLE approach, we present further evidence of a protective association of MMC against HIV and HSV-2 in this hyper-endemic South African setting. TMLE has the potential to enhance the evidence base for recommendations that embrace the effect of public health interventions on health or disease outcomes
Prevalence and Risk Factors for HIV Infection Among Heterosexual Men Recruited from Socializing Venues in Rural KwaZulu-Natal, South Africa
Determining HIV risk for Adolescent Girls and Young Women (Agyw) in relationships with “Blessers” and age-disparate partners
Different relationships present different HIV risk to AGYW. AGYW who had engaged in relationships with both a Blesser and an age-disparate partner were at greater HIV risk when examined against these relationships independent of one another. The data reveals the compounded HIV risk of being in both a transactional and age-disparate relationship
Depression symptoms, HIV testing, linkage to ART, and viral suppression among women in a high HIV burden district in KwaZulu-Natal, South Africa
Achieving the UNAIDS 90-90-90 targets by 2020 is contingent on identifying and addressing mental health challenges that may affect HIV testing and treatment-related behaviors. This study is based on survey data from KwaZulu-Natal, South Africa (2014-2015). HIV positive women who reported higher depression scores had a lower odds of having tested previously for HIV (15-25 years: AOR = 0.90, 95% CI [0.83, 0.98]; 26-49 years: AOR = 0.90, 95% CI [0.8…
Exposure to comprehensive sexuality education in schools in South Africa
Comprehensive sexuality education (CSE) is seen as a key instrument through which to affect behaviour and improve sexual and reproductive health (SRH) outcomes amongst adolescents. However, few studies have to date evaluated key SRH outcomes following exposure to CSE within a school setting. This study estimates the association between CSE and HIV testing and HIV testing self-efficacy amongst HIV positive adolescent girls. Data were collected fro…
Syndemic mapping of HIV and other STIs in KwaZulu-Natal
Syndemics involving Human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs) remain a major public health challenge in sub-Saharan Africa, and understanding their spatial and temporal dynamics is critical for effective interventions. Using data from two consecutive, population-based cross-sectional surveys conducted in 2014 and 2015 under the HIV Incidence Provincial Surveillance System (HIPSS) in KwaZulu-Natal, South A…
Spatial Analysis of HIV Determinants Among Females Aged 15–34 in KwaZulu Natal, South Africa
HIV remains a major public health challenge in sub-Saharan Africa, with South Africa bearing the highest burden. This study confirms that KwaZulu-Natal (KZN) is a hotspot, with a high HIV prevalence of 47.4% (95% CI: 45.7-49.1) among females aged 15-34. We investigated the spatial distribution and key socio-demographic, behavioural, and economic factors associated with HIV prevalence in this group using a Bayesian spatial logistic regression mode…
Medicine (17 obras) · HIV/AIDS Research and Interventions (15 obras) · Adolescent Sexual and Reproductive Health (13 obras) · Environmental health (13 obras) · Demography (12 obras) · Demography (10 obras) · Human immunodeficiency virus (HIV (10 obras) · HIV, Drug Use, Sexual Risk (9 obras) · Public health (9 obras) · Internal Medicine (8 obras)