C Metcalfe
Dados Biográficos
| ID | 49402 |
|---|---|
| NOME | C Metcalfe |
| PRENOMES | C |
| SOBRENOME | Metcalfe |
| ASSINATURA | METCALFE C |
| AFILIAÇÕES | University of Bristol |
| ORCID | 0000-0001-8318-8907 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 32 |
| TOTAL DE CITAÇÕES | 91 |
| TOTAL COMO AUTOR | 32 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2001 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 6 |
Preventing suicide by restricting access to Highly Hazardous Pesticides (HHPs)
Suicide is a leading cause of death worldwide. A previous systematic review showed that regulations limiting access to highly hazardous pesticides (HHPs) were successful in preventing suicides. As the WHO strongly supports regulation of pesticides, we aimed to update and strengthen the evidence on the effectiveness of HHP bans. We conducted a systematic review by searching MEDLINE, Embase, and PsycINFO databases in March 2024 for manuscripts publ…
Trends of poisoning types in Sri Lanka
The implementation of national bans of HHPs led to a reduction in number of admissions as well as CF due to pesticide poisoning in hospitals in Sri Lanka, with no evidence of substitution to other types of poisonings. The reversal of the upward trend in hospital admissions due to pesticide and medicinal poisonings suggests that the bans contributed to a reduction in admissions from these types of poisoning
Acceptability of integrating smoking cessation treatment into routine care for people with mental illness
INTRODUCTION: Improving Access to Psychological Therapies (IAPTs) Services could offer smoking cessation treatment to improve physical and psychological outcomes for service users, but it currently does not. This study aimed to understand participants' views and experiences of receiving a novel smoking cessation intervention as part of the ESCAPE trial (intEgrating Smoking Cessation treatment As part of usual Psychological care for dEpression and…
The Impact of the Covid-19 Pandemic and Lockdowns on Self-Poisoning and Suicide in Sri Lanka
Evidence from high-income countries suggests that the impact of COVID-19 on suicide and self-harm has been limited, but evidence from low- and middle-income countries is lacking. Using data from a hospital-based self-poisoning register (January 2019-December 2021) and data from national records (2016-2021) of suicide in Sri Lanka, we aimed to assess the impact of the pandemic on both self-poisoning and suicide. We examined changes in admissions f…
Protocol to evaluate the effectiveness and cost-effectiveness of an environmental nutrition and physical activity intervention in nurseries (Nutrition and Physical Activity Self Assessment for Child C…
ISRCTN33134697, 31/10/2019
HepFREEPak
This study was registered on clinicaltrials.gov (NCT04943588) on June 29, 2021
Action 3
Many children are not sufficiently physically active. We conducted a cluster-randomised feasibility trial of a revised after-school physical activity (PA) programme delivered by trained teaching assistants (TAs) to assess the potential evidence of promise for increasing moderate-to-vigorous physical activity (MVPA). Participants ( n = 335) aged 8−10 years were recruited from 12 primary schools in South West England. Six schools were randomised to…
Evaluation of an intervention to promote walking during the commute to work
ISRCTN15009100 . Prospectively registered. (Date assigned: 10/12/2014)
Action 3
ISRCTN34001941 . Prospectively registered 01/12/2016
Cross-sectional analysis of physical activity in 2–4-year-olds in England with paediatric quality of life and family expenditure on physical activity
Children in this sample were not meeting the recommended 180 min of daily physical activity. The 2-4-year-olds were most active on nursery days. There is no evidence of an association between better PedsQL physical scores and higher levels of MVPA. There was no evidence of an association between expenditure on physical activity and time spent physically active. Further examination in larger representative datasets is needed
A physical activity, nutrition and oral health intervention in nursery settings
ISRCTN16287377 (10 Apr 2015)
Acceptability, internal consistency and test–retest reliability of scales to assess parental and nursery staff’s self-efficacy, motivation and knowledge in relation to pre-school children’s nutrition,…
Objective To determine the acceptability, internal consistency and test–retest reliability of self-efficacy, motivation and knowledge scales relating to pre-school children’s nutrition, oral health and physical activity. Design An online questionnaire was completed twice with an interval of 7–11d. Setting Online questionnaires were sent to participants via email from nursery managers. The parent questionnaire was also available on the parenting w…
Association of diet in nurseries and physical activity with zBMI in 2–4-year olds in England
ISRCTN16287377 . Registered 12 June 2014
Using conversation analytic methods to assess fidelity to a talk-based healthcare intervention for frequently attending patients
Regional variation in suicide rates in Sri Lanka between 1955 and 2011
The findings provide some support for the hypothesis that changes in access to pesticides contributed to the marked fluctuations in Sri Lanka's suicide rate, but the impact of other factors cannot be ruled out
Study protocol
ISRCTN15009100 (10 December 2014)
Suicide in Sri Lanka 1975–2012
The epidemiology of suicide in Sri Lanka has changed noticeably in the last 30 years. The introduction of pesticide regulations in Sri Lanka coincides with a reduction in suicide rates, with evidence of limited method substitution
Suicide and the 2008 economic recession
The negative impacts of previous economic recessions on suicide rates have largely been attributed to rapid rises in unemployment in the context of inadequate social and work protection programmes. We have investigated trends in indicators of the 2008 economic recession and trends in suicide rates in England and Wales in men and women of working age (16-64 years old) for the period 2001-2011, before, during and after the economic recession, our a…
OP89 The Association of Parental Fatal and Non-Fatal Suicidal Behaviour with Offspring Suicidalbehaviourand Depression
Background Children whose parents die by, or attempt, suicide are believed to be at greater risk of suicidal behaviours and affective disorders. We systematically reviewed the literature on the association of parental fatal and non-fatal suicidal behaviours with offspring suicidal behaviour and depression and, using meta-analysis, estimated the strength of these associations. We further investigated the role of parental and offspring gender, and …
OP64 Parental Suicide Attempt and Offspring Self-Harm and Suicidal Thoughts
Background Exposure to parental self-harm has been linked to an increased risk of self-harm and suicidal thoughts in their offspring. Much of the available evidence is from population registers or clinical samples and relates to parental death by suicide; few studies have investigated associations of non-fatal suicide attempts in parents with community presenting non-fatal self-harm and suicidal thoughts in offspring. We studied the association o…
A community-based cluster randomised trial of safe storage to reduce pesticide self-poisoning in rural Sri Lanka
This paper describes a large effectiveness study of a community intervention to reduce the burden of intentional poisoning in rural Sri Lanka. The study builds on a strong partnership between provincial health services, local and international researchers, and local communities. We discuss issues in relation to randomisation and contamination, engaging control villages, the intervention, and strategies to improve adherence
Clinical versus economic interpretations of RCT results - Mixed messages
Background For randomised controlled trials (RCT), the sample size needed to detect an important effect on clinical outcome is commonly believed to be insufficient to firmly establish the efficiency of the intervention. Objectives To review cost-utility analyses (CUAs) conducted alongside RCTs to determine: (1) if cost-effectiveness is considered in sample size calculations, (2) the frequency with which economic conclusions conflict with clinical…
Adjusting misclassification of outcome in case-control studies
Objective Misclassification of outcome may cause biased estimation for associations of potential risk factors with important diseases. For example, case-control studies of localised prostate cancer frequently measure blood levels of circulating prostate specific antigen (PSA) in healthy men and biopsy those with an elevated level. Inevitably, some men with prostate cancer will be misclassified as controls, either because they do not have an eleva…
Regulatory guidance on prescribing selective serotonin reuptake inhibitor antidepressants to young people
In 2003 many international medicine regulatory agencies issued warnings concerning the prescribing of selective serotonin reuptake inhibitor (SSRI) antidepressants to young people, due to concerns that they increase risks of suicidal behaviour. A US study suggested that this action may have actually caused an increase in suicide rates due to under-treatment of depression, whilst a UK study did not find such an increase
Does consideration of either psychological or material disadvantage improve coronary risk prediction? Prospective observational study of Scottish men
Objective: To assess the value of psychosocial risk factors in discriminating between individuals at higher and lower risk of coronary heart disease, using risk prediction equations. Design: Prospective observational study. Setting: Scotland. Participants: 5191 employed men aged 35 to 64 years and free of coronary heart disease at study enrolment Main outcome measures: Area under receiver operating characteristic (ROC) curves for risk prediction …
Is subjective social status a more important determinant of health than objective social status? Evidence from a prospective observational study of Scottish men
Are the effects of psychosocial exposures attributable to confounding? Evidence from a prospective observational study on psychological stress and mortality
STUDY OBJECTIVES: To examine the association between perceived psychological stress and cause specific mortality in a population where perceived stress was not associated with material disadvantage. DESIGN: Prospective observational study with follow up of 21 years and repeat screening of half the cohort five years from baseline. Measures included perceived psychological stress, coronary risk factors, and indices of lifecourse socioeconomic posit…
Suicide and the 2008 economic recession
The negative impacts of previous economic recessions on suicide rates have largely been attributed to rapid rises in unemployment in the context of inadequate social and work protection programmes. We have investigated trends in indicators of the 2008 economic recession and trends in suicide rates in England and Wales in men and women of working age (16-64 years old) for the period 2001-2011, before, during and after the economic recession, our a…
Change in job satisfaction, and its association with self-reported stress, cardiovascular risk factors and mortality
Frequent job change and associated health
Using conversation analytic methods to assess fidelity to a talk-based healthcare intervention for frequently attending patients
Subjective and objective status and health
Limitations of adjustment for reporting tendency in observational studies of stress and self reported coronary heart disease
Recently, observational evidence has been suggested to show a causal association between various "psychosocial" exposures, including psychological stress, and heart disease. Much of this evidence derives from studies in which a self reported psychosocial exposure is related to an outcome dependent on the subjective experience of coronary heart disease (CHD) symptoms. Such outcomes may be measured using standard symptom questionnaires (like the Ro…
Individual employment histories and subsequent cause specific hospital admissions and mortality
It is a widely held view that the labour market is demanding increased levels of flexibility, and that this is causing greater psychosocial stress among employees.1 Such stress may affect health, either through neuroendocrine pathways, or through increases in behaviours linked with poor health.2 Previously we presented evidence linking an unstable employment history, as measured by a greater number of job changes and shorter duration of current j…
Individual employment histories and subsequent cause specific hospital admissions and mortality
It is a widely held view that the labour market is demanding increased levels of flexibility, and that this is causing greater psychosocial stress among employees.1 Such stress may affect health, either through neuroendocrine pathways, or through increases in behaviours linked with poor health.2 Previously we presented evidence linking an unstable employment history, as measured by a greater number of job changes and shorter duration of current j…
Are the effects of psychosocial exposures attributable to confounding? Evidence from a prospective observational study on psychological stress and mortality
STUDY OBJECTIVES: To examine the association between perceived psychological stress and cause specific mortality in a population where perceived stress was not associated with material disadvantage. DESIGN: Prospective observational study with follow up of 21 years and repeat screening of half the cohort five years from baseline. Measures included perceived psychological stress, coronary risk factors, and indices of lifecourse socioeconomic posit…
Limitations of adjustment for reporting tendency in observational studies of stress and self reported coronary heart disease
Recently, observational evidence has been suggested to show a causal association between various "psychosocial" exposures, including psychological stress, and heart disease. Much of this evidence derives from studies in which a self reported psychosocial exposure is related to an outcome dependent on the subjective experience of coronary heart disease (CHD) symptoms. Such outcomes may be measured using standard symptom questionnaires (like the Ro…
Change in job satisfaction, and its association with self-reported stress, cardiovascular risk factors and mortality
Frequent job change and associated health
Is subjective social status a more important determinant of health than objective social status? Evidence from a prospective observational study of Scottish men
Subjective and objective status and health
Does consideration of either psychological or material disadvantage improve coronary risk prediction? Prospective observational study of Scottish men
Objective: To assess the value of psychosocial risk factors in discriminating between individuals at higher and lower risk of coronary heart disease, using risk prediction equations. Design: Prospective observational study. Setting: Scotland. Participants: 5191 employed men aged 35 to 64 years and free of coronary heart disease at study enrolment Main outcome measures: Area under receiver operating characteristic (ROC) curves for risk prediction …
Regulatory guidance on prescribing selective serotonin reuptake inhibitor antidepressants to young people
In 2003 many international medicine regulatory agencies issued warnings concerning the prescribing of selective serotonin reuptake inhibitor (SSRI) antidepressants to young people, due to concerns that they increase risks of suicidal behaviour. A US study suggested that this action may have actually caused an increase in suicide rates due to under-treatment of depression, whilst a UK study did not find such an increase
Adjusting misclassification of outcome in case-control studies
Objective Misclassification of outcome may cause biased estimation for associations of potential risk factors with important diseases. For example, case-control studies of localised prostate cancer frequently measure blood levels of circulating prostate specific antigen (PSA) in healthy men and biopsy those with an elevated level. Inevitably, some men with prostate cancer will be misclassified as controls, either because they do not have an eleva…
A community-based cluster randomised trial of safe storage to reduce pesticide self-poisoning in rural Sri Lanka
This paper describes a large effectiveness study of a community intervention to reduce the burden of intentional poisoning in rural Sri Lanka. The study builds on a strong partnership between provincial health services, local and international researchers, and local communities. We discuss issues in relation to randomisation and contamination, engaging control villages, the intervention, and strategies to improve adherence
Clinical versus economic interpretations of RCT results - Mixed messages
Background For randomised controlled trials (RCT), the sample size needed to detect an important effect on clinical outcome is commonly believed to be insufficient to firmly establish the efficiency of the intervention. Objectives To review cost-utility analyses (CUAs) conducted alongside RCTs to determine: (1) if cost-effectiveness is considered in sample size calculations, (2) the frequency with which economic conclusions conflict with clinical…
OP89 The Association of Parental Fatal and Non-Fatal Suicidal Behaviour with Offspring Suicidalbehaviourand Depression
Background Children whose parents die by, or attempt, suicide are believed to be at greater risk of suicidal behaviours and affective disorders. We systematically reviewed the literature on the association of parental fatal and non-fatal suicidal behaviours with offspring suicidal behaviour and depression and, using meta-analysis, estimated the strength of these associations. We further investigated the role of parental and offspring gender, and …
OP64 Parental Suicide Attempt and Offspring Self-Harm and Suicidal Thoughts
Background Exposure to parental self-harm has been linked to an increased risk of self-harm and suicidal thoughts in their offspring. Much of the available evidence is from population registers or clinical samples and relates to parental death by suicide; few studies have investigated associations of non-fatal suicide attempts in parents with community presenting non-fatal self-harm and suicidal thoughts in offspring. We studied the association o…
Suicide in Sri Lanka 1975–2012
The epidemiology of suicide in Sri Lanka has changed noticeably in the last 30 years. The introduction of pesticide regulations in Sri Lanka coincides with a reduction in suicide rates, with evidence of limited method substitution
Suicide and the 2008 economic recession
The negative impacts of previous economic recessions on suicide rates have largely been attributed to rapid rises in unemployment in the context of inadequate social and work protection programmes. We have investigated trends in indicators of the 2008 economic recession and trends in suicide rates in England and Wales in men and women of working age (16-64 years old) for the period 2001-2011, before, during and after the economic recession, our a…
Study protocol
ISRCTN15009100 (10 December 2014)
Regional variation in suicide rates in Sri Lanka between 1955 and 2011
The findings provide some support for the hypothesis that changes in access to pesticides contributed to the marked fluctuations in Sri Lanka's suicide rate, but the impact of other factors cannot be ruled out
Association of diet in nurseries and physical activity with zBMI in 2–4-year olds in England
ISRCTN16287377 . Registered 12 June 2014
Using conversation analytic methods to assess fidelity to a talk-based healthcare intervention for frequently attending patients
Action 3
Many children are not sufficiently physically active. We conducted a cluster-randomised feasibility trial of a revised after-school physical activity (PA) programme delivered by trained teaching assistants (TAs) to assess the potential evidence of promise for increasing moderate-to-vigorous physical activity (MVPA). Participants ( n = 335) aged 8−10 years were recruited from 12 primary schools in South West England. Six schools were randomised to…
Evaluation of an intervention to promote walking during the commute to work
ISRCTN15009100 . Prospectively registered. (Date assigned: 10/12/2014)
Action 3
ISRCTN34001941 . Prospectively registered 01/12/2016
Cross-sectional analysis of physical activity in 2–4-year-olds in England with paediatric quality of life and family expenditure on physical activity
Children in this sample were not meeting the recommended 180 min of daily physical activity. The 2-4-year-olds were most active on nursery days. There is no evidence of an association between better PedsQL physical scores and higher levels of MVPA. There was no evidence of an association between expenditure on physical activity and time spent physically active. Further examination in larger representative datasets is needed
A physical activity, nutrition and oral health intervention in nursery settings
ISRCTN16287377 (10 Apr 2015)
Medicine (29 obras) · Internal Medicine (15 obras) · Public health (14 obras) · Environmental health (13 obras) · Demography (12 obras) · Biostatistics (11 obras) · Gerontology (11 obras) · Psychiatry (10 obras) · Demography (9 obras) · Injury prevention (9 obras)