Benjamin L Ebert

• National Trends in Hospitalizations for Sickle Cell Disease in the United States Following the FDA Approval of Hydroxyurea, 1998–2008

  Maureen M Okam, Maureen Okam et al.•ARTICLE•Medical Care•2014•Referências: 8

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  BACKGROUND: Patients with sickle cell disease (SCD) can suffer frequent hospital admissions for painful vasoocclusive crises. Hydroxyurea was approved by the FDA in 1998 to decrease the morbidity of SCD, but nationwide hospitalizations for SCD in the United States since 1998 have not been evaluated. We hypothesized that the availability of hydroxyurea for SCD would be associated with a decrease in hospitalizations for SCD over time. OBJECTIVE: To…

• Gene set enrichment analysis

  Open Access•Aravind Subramanian, Pablo Tamayo et al.•ARTICLE•Proceedings of the National…•2005

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  Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge. Here, we describe a powerful analytical method called Gene Set Enrichment Analysis (GSEA) for interpreting gene expression data. The method derives its power by focusing on gene sets, that is, groups of genes that share common biological function, chromosomal location, or regu…

• Gene set enrichment analysis

  Open Access•Aravind Subramanian, Pablo Tamayo et al.•ARTICLE•Proceedings of the National…•2005

  Incluir item

  Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge. Here, we describe a powerful analytical method called Gene Set Enrichment Analysis (GSEA) for interpreting gene expression data. The method derives its power by focusing on gene sets, that is, groups of genes that share common biological function, chromosomal location, or regu…

• National Trends in Hospitalizations for Sickle Cell Disease in the United States Following the FDA Approval of Hydroxyurea, 1998–2008

  Maureen M Okam, Maureen Okam et al.•ARTICLE•Medical Care•2014•Referências: 8

  Incluir item

  BACKGROUND: Patients with sickle cell disease (SCD) can suffer frequent hospital admissions for painful vasoocclusive crises. Hydroxyurea was approved by the FDA in 1998 to decrease the morbidity of SCD, but nationwide hospitalizations for SCD in the United States since 1998 have not been evaluated. We hypothesized that the availability of hydroxyurea for SCD would be associated with a decrease in hospitalizations for SCD over time. OBJECTIVE: To…

Bioinformatics (1 obra) · Bioinformatics and Genomic Networks (1 obra) · Biology (1 obra) · Blood groups and transfusion (1 obra) · Cohort study (1 obra) · Computational biology (1 obra) · Computer Science (1 obra) · Confidence interval (1 obra) · Disease (1 obra) · Emergency Medicine (1 obra)