Fabian H Leendertz
Dados Biográficos
| ID | 5207995 |
|---|---|
| NOME | Fabian H Leendertz |
| PRENOMES | Fabian H |
| SOBRENOME | Leendertz |
| ASSINATURA | LEENDERTZ F H |
| AFILIAÇÕES | Robert Koch Institute |
| ORCID | 0000-0002-2169-7375 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAÇÕES | 12 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2006 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2024 |
| ÍNDICE H | 1 |
Oesophagostomum stephanostomum causing parasitic granulomas in wild chimpanzees ( Pan troglodytes verus ) of Taï National Park, Côte d'Ivoire
Nematodes belonging to the genus Oesophagostomum frequently infect wild chimpanzees ( Pan troglodytes ) across widely separated field sites. Nodular lesions (granulomas) containing Oesophagostomum are commonly seen in the abdomen of infected chimpanzees post‐mortem. At Taï National Park, Côte d'Ivoire, previous studies have identified larvae of a variety of Oesophagostomum spp. in wild chimpanzee stool, based on sequencing of larval DNA, and nodu…
Christophe Boesch (1951–2024)
International audience
Protecting great apes from disease
The emergence of infectious diseases, such as COVID‐19, impacts livelihood strategies and conservation tools reliant on human‐wildlife interactions, such as wildlife‐based tourism and research. This is particularly relevant to great ape conservation, as humans and great apes are susceptible to being infected by similar pathogens. Evidence‐based strategies are required to prevent infectious disease transmission to great apes and people involved in…
The Movement of Pathogen Carrying Flies at the Human–Wildlife Interface
Flies form high-density associations with human settlements and groups of nonhuman primates and are implicated in transmitting pathogens. We investigate the movement of nonhuman primate-associated flies across landscapes surrounding Kibale National Park, Uganda, using a mark–recapture experiment. Flies were marked in nine nonhuman primate groups at the forest edge ( $$\overline{x}$$ x ̄ = 929 flies per group), and we then attempted to recapture t…
The cost of living in larger primate groups includes higher fly densities
Flies are implicated in carrying and mechanically transmitting many primate pathogens. We investigated how fly associations vary across six monkey species ( Cercopithecus ascanius, Cercopithecus mitis , Colobus guereza , Lophocebus albigena , Papio anubis , and Piliocolobus tephrosceles ) and whether monkey group size impacts fly densities. Fly densities were generally higher inside groups than outside them, and considering data from these primat…
The Use of Neopterin as a Noninvasive Marker in Monitoring Diseases in Wild Chimpanzees
Human Respiratory Syncytial Virus and Streptococcus pneumoniae Infection in Wild Bonobos
Human quarantine
Due to their genetic relatedness, great apes are highly susceptible to common human respiratory pathogens. Although most respiratory pathogens, such as human respiratory syncytial virus (HRSV) and human metapneumovirus (HMPV), rarely cause severe disease in healthy human adults, they are associated with considerable morbidity and mortality in wild great apes habituated to humans for research or tourism. To prevent pathogen transmission, most grea…
Obituary
Codetection of Respiratory Syncytial Virus in Habituated Wild Western Lowland Gorillas and Humans During a Respiratory Disease Outbreak
Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses
Contact to Non-human Primates and Risk Factors for Zoonotic Disease Emergence in the Taï Region, Côte d’Ivoire
Adenovirus in Rural Côte D`Ivoire
A cautionary note on fecal sampling and molecular epidemiology in predatory wild great apes
Fecal samples are an important source of information on parasites (viruses, prokaryotes, or eukaryotes) infecting wild great apes. Molecular analysis of fecal samples has already been used for deciphering the origins of major human pathogens such as HIV-1 or Plasmodium falciparum. However, for apes that hunt (chimpanzees and bonobos), detection of parasite nucleic acids may reflect either true infection of the host of interest or ingestion of an …
Field immobilization for treatment of an unknown illness in a wild chimpanzee (Pan troglodytes schweinfurthii) at Gombe National Park, Tanzania
Nasopharyngeal colonization by potentially pathogenic bacteria found in healthy semi‐captive wild‐born chimpanzees in Uganda
Information on the chimpanzee nasopharygeal colonization in captive sanctuaries and in the wild is rare. This study was undertaken to establish the nasopharygeal colonization and potential bacterial pathogens in sanctuary chimpanzees as a basis for improving chimpanzee and employee health. Nasopharygeal colonization of 39 healthy chimpanzees were analyzed by microbiological cultivation method and polymerase chain reaction (PCR) targeting the bact…
Drug‐Resistant Human S taphylococcus Aureus in Sanctuary Apes Pose a Threat to Endangered Wild Ape Populations
Reintroduction of sanctuary apes to natural habitat is considered an important tool for conservation; however, reintroduction has the potential to endanger resident wild apes through the introduction of human pathogens. We found a high prevalence of drug‐resistant, human‐associated lineages of S taphylococcus aureus in sanctuary chimpanzees ( P an troglodytes ) from Zambia and Uganda. This pathogen is associated with skin and soft tissue diseases…
Molecular diversity of entodiniomorphid ciliate Troglodytella abrassarti and its coevolution with chimpanzees
The entodiniomorphid ciliate Troglodytella abrassarti is a colonic mutualist of great apes. Its host specificity makes it a suitable model for studies of primate evolution. We explored molecular diversity of T. abrassarti with regard to large geographical distribution and taxonomic diversity of its most common host, the chimpanzee. We found a very low diversification of T. abrassarti in chimpanzees across Africa. Distribution of two types of T. a…
Noninvasive Monitoring of Respiratory Viruses in Wild Chimpanzees
A longitudinal study of urinary dipstick parameters in wild chimpanzees ( Pan troglodytes verus ) in Côte d'Ivoire
We performed 796 dip‐stick tests on urine from 100 wild West African chimpanzees ( Pan troglodytes verus ) from 4 habituated groups in the tropical rain forest of Taï National Park, Cote d'Ivoire, to establish reference values for health monitoring. Specific gravity was also measured on 359 urine samples from 62 chimpanzees. The effect of age, sex, group, month, estrus, pregnancy, meat consumption, and acute respiratory disease on pH, leucocytes,…
Examining Landscape Factors Influencing Relative Distribution of Mosquito Genera and Frequency of Virus Infection
Mosquito-borne infections cause some of the most debilitating human diseases, including yellow fever and malaria, yet we lack an understanding of how disease risk scales with human-driven habitat changes. We present an approach to study variation in mosquito distribution and concomitant viral infections on the landscape level. In a pilot study we analyzed mosquito distribution along a 10-km transect of a West African rainforest area, which includ…
Pandemic Human Viruses Cause Decline of Endangered Great Apes
Commentary on “Pandemic Human Viruses Cause Decline of Endangered Great Apes,” by Köndgen et al., 2008, Current Biology 18
Integrative approaches to the study of primate infectious disease
The close phylogenetic relationship between humans and nonhuman primates, coupled with the exponential expansion of human populations and human activities within primate habitats, has resulted in exceptionally high potential for pathogen exchange. Emerging infectious diseases are a consequence of this process that has the capacity to threaten global health and drive primate population declines. Integration of standardized empirical data collectio…
Anthrax in Western and Central African great apes
During the period of December 2004 to January 2005, Bacillus anthracis killed three wild chimpanzees ( Pan troglodytes troglodytes ) and one gorilla ( Gorilla gorilla gorilla ) in a tropical forest in Cameroon. While this is the second anthrax outbreak in wild chimpanzees, this is the first case of anthrax in gorillas ever reported. The number of great apes in Central Africa is dramatically declining and the populations are seriously threatened b…
Integrative approaches to the study of primate infectious disease
The close phylogenetic relationship between humans and nonhuman primates, coupled with the exponential expansion of human populations and human activities within primate habitats, has resulted in exceptionally high potential for pathogen exchange. Emerging infectious diseases are a consequence of this process that has the capacity to threaten global health and drive primate population declines. Integration of standardized empirical data collectio…
Anthrax in Western and Central African great apes
During the period of December 2004 to January 2005, Bacillus anthracis killed three wild chimpanzees ( Pan troglodytes troglodytes ) and one gorilla ( Gorilla gorilla gorilla ) in a tropical forest in Cameroon. While this is the second anthrax outbreak in wild chimpanzees, this is the first case of anthrax in gorillas ever reported. The number of great apes in Central Africa is dramatically declining and the populations are seriously threatened b…
Pandemic Human Viruses Cause Decline of Endangered Great Apes
Commentary on “Pandemic Human Viruses Cause Decline of Endangered Great Apes,” by Köndgen et al., 2008, Current Biology 18
Integrative approaches to the study of primate infectious disease
The close phylogenetic relationship between humans and nonhuman primates, coupled with the exponential expansion of human populations and human activities within primate habitats, has resulted in exceptionally high potential for pathogen exchange. Emerging infectious diseases are a consequence of this process that has the capacity to threaten global health and drive primate population declines. Integration of standardized empirical data collectio…
Examining Landscape Factors Influencing Relative Distribution of Mosquito Genera and Frequency of Virus Infection
Mosquito-borne infections cause some of the most debilitating human diseases, including yellow fever and malaria, yet we lack an understanding of how disease risk scales with human-driven habitat changes. We present an approach to study variation in mosquito distribution and concomitant viral infections on the landscape level. In a pilot study we analyzed mosquito distribution along a 10-km transect of a West African rainforest area, which includ…
Noninvasive Monitoring of Respiratory Viruses in Wild Chimpanzees
A longitudinal study of urinary dipstick parameters in wild chimpanzees ( Pan troglodytes verus ) in Côte d'Ivoire
We performed 796 dip‐stick tests on urine from 100 wild West African chimpanzees ( Pan troglodytes verus ) from 4 habituated groups in the tropical rain forest of Taï National Park, Cote d'Ivoire, to establish reference values for health monitoring. Specific gravity was also measured on 359 urine samples from 62 chimpanzees. The effect of age, sex, group, month, estrus, pregnancy, meat consumption, and acute respiratory disease on pH, leucocytes,…
Drug‐Resistant Human S taphylococcus Aureus in Sanctuary Apes Pose a Threat to Endangered Wild Ape Populations
Reintroduction of sanctuary apes to natural habitat is considered an important tool for conservation; however, reintroduction has the potential to endanger resident wild apes through the introduction of human pathogens. We found a high prevalence of drug‐resistant, human‐associated lineages of S taphylococcus aureus in sanctuary chimpanzees ( P an troglodytes ) from Zambia and Uganda. This pathogen is associated with skin and soft tissue diseases…
Molecular diversity of entodiniomorphid ciliate Troglodytella abrassarti and its coevolution with chimpanzees
The entodiniomorphid ciliate Troglodytella abrassarti is a colonic mutualist of great apes. Its host specificity makes it a suitable model for studies of primate evolution. We explored molecular diversity of T. abrassarti with regard to large geographical distribution and taxonomic diversity of its most common host, the chimpanzee. We found a very low diversification of T. abrassarti in chimpanzees across Africa. Distribution of two types of T. a…
Field immobilization for treatment of an unknown illness in a wild chimpanzee (Pan troglodytes schweinfurthii) at Gombe National Park, Tanzania
Nasopharyngeal colonization by potentially pathogenic bacteria found in healthy semi‐captive wild‐born chimpanzees in Uganda
Information on the chimpanzee nasopharygeal colonization in captive sanctuaries and in the wild is rare. This study was undertaken to establish the nasopharygeal colonization and potential bacterial pathogens in sanctuary chimpanzees as a basis for improving chimpanzee and employee health. Nasopharygeal colonization of 39 healthy chimpanzees were analyzed by microbiological cultivation method and polymerase chain reaction (PCR) targeting the bact…
Contact to Non-human Primates and Risk Factors for Zoonotic Disease Emergence in the Taï Region, Côte d’Ivoire
Adenovirus in Rural Côte D`Ivoire
A cautionary note on fecal sampling and molecular epidemiology in predatory wild great apes
Fecal samples are an important source of information on parasites (viruses, prokaryotes, or eukaryotes) infecting wild great apes. Molecular analysis of fecal samples has already been used for deciphering the origins of major human pathogens such as HIV-1 or Plasmodium falciparum. However, for apes that hunt (chimpanzees and bonobos), detection of parasite nucleic acids may reflect either true infection of the host of interest or ingestion of an …
Codetection of Respiratory Syncytial Virus in Habituated Wild Western Lowland Gorillas and Humans During a Respiratory Disease Outbreak
Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses
The Use of Neopterin as a Noninvasive Marker in Monitoring Diseases in Wild Chimpanzees
Human Respiratory Syncytial Virus and Streptococcus pneumoniae Infection in Wild Bonobos
Human quarantine
Due to their genetic relatedness, great apes are highly susceptible to common human respiratory pathogens. Although most respiratory pathogens, such as human respiratory syncytial virus (HRSV) and human metapneumovirus (HMPV), rarely cause severe disease in healthy human adults, they are associated with considerable morbidity and mortality in wild great apes habituated to humans for research or tourism. To prevent pathogen transmission, most grea…
Obituary
Protecting great apes from disease
The emergence of infectious diseases, such as COVID‐19, impacts livelihood strategies and conservation tools reliant on human‐wildlife interactions, such as wildlife‐based tourism and research. This is particularly relevant to great ape conservation, as humans and great apes are susceptible to being infected by similar pathogens. Evidence‐based strategies are required to prevent infectious disease transmission to great apes and people involved in…
The Movement of Pathogen Carrying Flies at the Human–Wildlife Interface
Flies form high-density associations with human settlements and groups of nonhuman primates and are implicated in transmitting pathogens. We investigate the movement of nonhuman primate-associated flies across landscapes surrounding Kibale National Park, Uganda, using a mark–recapture experiment. Flies were marked in nine nonhuman primate groups at the forest edge ( $$\overline{x}$$ x ̄ = 929 flies per group), and we then attempted to recapture t…
The cost of living in larger primate groups includes higher fly densities
Flies are implicated in carrying and mechanically transmitting many primate pathogens. We investigated how fly associations vary across six monkey species ( Cercopithecus ascanius, Cercopithecus mitis , Colobus guereza , Lophocebus albigena , Papio anubis , and Piliocolobus tephrosceles ) and whether monkey group size impacts fly densities. Fly densities were generally higher inside groups than outside them, and considering data from these primat…
Oesophagostomum stephanostomum causing parasitic granulomas in wild chimpanzees ( Pan troglodytes verus ) of Taï National Park, Côte d'Ivoire
Nematodes belonging to the genus Oesophagostomum frequently infect wild chimpanzees ( Pan troglodytes ) across widely separated field sites. Nodular lesions (granulomas) containing Oesophagostomum are commonly seen in the abdomen of infected chimpanzees post‐mortem. At Taï National Park, Côte d'Ivoire, previous studies have identified larvae of a variety of Oesophagostomum spp. in wild chimpanzee stool, based on sequencing of larval DNA, and nodu…
Christophe Boesch (1951–2024)
International audience
Biology (24 obras) · Medicine (15 obras) · Primate Behavior and Ecology (15 obras) · Ecology (14 obras) · Animal ecology (13 obras) · Zoology (12 obras) · Zoonotic diseases and public health (11 obras) · Geography (10 obras) · Disease (7 obras) · Virology (7 obras)