Nicholas G Martin
Dados Biográficos
| ID | 5220189 |
|---|---|
| NOME | Nicholas G Martin |
| PRENOMES | Nicholas G |
| SOBRENOME | Martin |
| ASSINATURA | MARTIN N G |
| AFILIAÇÕES | QIMR Berghofer Medical Research Institute |
| VERIFICADO | Não |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAÇÕES | 70 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1997 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2022 |
| ÍNDICE H | 5 |
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Comorbid Chronic Pain and Depression
The bidirectional relationship between depression and chronic pain is well-recognized, but their clinical management remains challenging. Here we characterize the shared risk factors and outcomes for their comorbidity in the Australian Genetics of Depression cohort study ( N = 13,839). Participants completed online questionnaires about chronic pain, psychiatric symptoms, comorbidities, treatment response and general health. Logistic regression mo…
Neuroticism as a Predictor of Frailty in Old Age
OBJECTIVE: Neuroticism is associated with poor health outcomes, but its contribution to the accumulation of health deficits in old age, that is, the frailty index, is largely unknown. We aimed to explore associations between neuroticism and frailty cross-sectionally and longitudinally, and to investigate the contribution of shared genetic influences. METHODS: Data were derived from the UK Biobank (UKB; n = 274,951), the Australian Over 50's Study…
A behavior genetic analysis of personality and loneliness
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Facial averageness and genetic quality
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Genome-wide association study identifies 74 loci associated with educational attainment
A test of the facultative calibration/reactive heritability model of extraversion
No relationship between intelligence and facial attractiveness in a large, genetically informative sample
Associations Between Depression and Anxiety Symptoms and Retinal Vessel Caliber in Adolescents and Young Adults
OBJECTIVE: Previous longitudinal studies suggest that depression and anxiety are associated with risk for cardiovascular disease. The aim of the present study was to test whether an association between depression and anxiety symptoms and retinal vessel caliber, an indicator of subclinical cardiovascular risk, is apparent as early as adolescence and young adulthood. METHODS: Participants were 865 adolescents and young adults who participated in th…
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Genetic Influences on Life Span and Its Relationship to Personality
OBJECTIVE: The relationship between personality and life span is not well understood, and no study to date has examined genetic influences underlying this relationship. The present study aimed to explore the phenotypic and genetic relationship between personality and life span, as well as genetic influences on all-cause mortality. METHODS: Prospective community-based study including 3752 twin individuals older than 50 years. Neuroticism, psychoti…
The general factor of personality
Sexual Orientation and Psychiatric Vulnerability
Relative Finger Lengths, Sex Differences, and Psychological Traits
Shared Temperament Risk Factors for Anorexia Nervosa
OBJECTIVE: To answer two questions about the nature of the relationship between anorexia nervosa (AN) and dimensional temperament traits: Which traits are comorbid with AN? Which traits share transmitted liabilities with AN? METHODS: A community sample of 1002 same-gender female twins was selected with respect to participation in two earlier waves of data collection. Measures of eating disorder diagnoses and features were ascertained through inte…
The Genetics of Voting
Height and 2D
Population Differences in Finger-Length Ratios
Psychological Masculinity‐Femininity via the Gender Diagnosticity Approach
Several aspects of the Gender Diagnosticity (GD) approach of Lippa (1995) to measuring the psychological trait of masculinity‐femininity within sexes were explored in four samples ranging from 363 to 5,859 individuals, including Swedish and Australian adults, U.S. elderly, and Australian adolescents. Two ways of deriving GD scales yielded highly similar results. Moderate stability of individual differences was found across ages 12 to 16 among ado…
Heritability of Adult Body Height
A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic architecture of body height varies between affluent western societies. We analysed twin data from eight countries comprising 30,111 complete twin pairs by using the univariate genetic model of the Mx statistical package. Body height and zygosity were se…
The Subtlety of Sex-Atypicality
How Accurate Is the Family History Method for Assessing Siblings' Sexual Orientation
The Consistency of Recalled Age at First Sexual Intercourse
It is widely believed that people can remember the age at which they first had sexual intercourse. Questions about age at onset are routinely asked in population sexual behaviour surveys and in clinical history-taking. However, there are limited test–retest data, especially with regard to individual differences in unreliable recall. In this study, telephone interviews and follow-ups an average of 15 months later were conducted with 570 non-virgin…
The Subtlety of Sex-Atypicality
Sexual Orientation and Psychiatric Vulnerability
Population Differences in Finger-Length Ratios
A behavior genetic analysis of personality and loneliness
How Accurate Is the Family History Method for Assessing Siblings' Sexual Orientation
The general factor of personality
Relative Finger Lengths, Sex Differences, and Psychological Traits
Height and 2D
The Consistency of Recalled Age at First Sexual Intercourse
It is widely believed that people can remember the age at which they first had sexual intercourse. Questions about age at onset are routinely asked in population sexual behaviour surveys and in clinical history-taking. However, there are limited test–retest data, especially with regard to individual differences in unreliable recall. In this study, telephone interviews and follow-ups an average of 15 months later were conducted with 570 non-virgin…
How Accurate Is the Family History Method for Assessing Siblings' Sexual Orientation
The Subtlety of Sex-Atypicality
Heritability of Adult Body Height
A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic architecture of body height varies between affluent western societies. We analysed twin data from eight countries comprising 30,111 complete twin pairs by using the univariate genetic model of the Mx statistical package. Body height and zygosity were se…
Psychological Masculinity‐Femininity via the Gender Diagnosticity Approach
Several aspects of the Gender Diagnosticity (GD) approach of Lippa (1995) to measuring the psychological trait of masculinity‐femininity within sexes were explored in four samples ranging from 363 to 5,859 individuals, including Swedish and Australian adults, U.S. elderly, and Australian adolescents. Two ways of deriving GD scales yielded highly similar results. Moderate stability of individual differences was found across ages 12 to 16 among ado…
Population Differences in Finger-Length Ratios
The Genetics of Voting
Height and 2D
Shared Temperament Risk Factors for Anorexia Nervosa
OBJECTIVE: To answer two questions about the nature of the relationship between anorexia nervosa (AN) and dimensional temperament traits: Which traits are comorbid with AN? Which traits share transmitted liabilities with AN? METHODS: A community sample of 1002 same-gender female twins was selected with respect to participation in two earlier waves of data collection. Measures of eating disorder diagnoses and features were ascertained through inte…
Relative Finger Lengths, Sex Differences, and Psychological Traits
The general factor of personality
Sexual Orientation and Psychiatric Vulnerability
Genetic Influences on Life Span and Its Relationship to Personality
OBJECTIVE: The relationship between personality and life span is not well understood, and no study to date has examined genetic influences underlying this relationship. The present study aimed to explore the phenotypic and genetic relationship between personality and life span, as well as genetic influences on all-cause mortality. METHODS: Prospective community-based study including 3752 twin individuals older than 50 years. Neuroticism, psychoti…
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Associations Between Depression and Anxiety Symptoms and Retinal Vessel Caliber in Adolescents and Young Adults
OBJECTIVE: Previous longitudinal studies suggest that depression and anxiety are associated with risk for cardiovascular disease. The aim of the present study was to test whether an association between depression and anxiety symptoms and retinal vessel caliber, an indicator of subclinical cardiovascular risk, is apparent as early as adolescence and young adulthood. METHODS: Participants were 865 adolescents and young adults who participated in th…
A test of the facultative calibration/reactive heritability model of extraversion
No relationship between intelligence and facial attractiveness in a large, genetically informative sample
Facial averageness and genetic quality
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Genome-wide association study identifies 74 loci associated with educational attainment
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Neuroticism as a Predictor of Frailty in Old Age
OBJECTIVE: Neuroticism is associated with poor health outcomes, but its contribution to the accumulation of health deficits in old age, that is, the frailty index, is largely unknown. We aimed to explore associations between neuroticism and frailty cross-sectionally and longitudinally, and to investigate the contribution of shared genetic influences. METHODS: Data were derived from the UK Biobank (UKB; n = 274,951), the Australian Over 50's Study…
A behavior genetic analysis of personality and loneliness
Comorbid Chronic Pain and Depression
The bidirectional relationship between depression and chronic pain is well-recognized, but their clinical management remains challenging. Here we characterize the shared risk factors and outcomes for their comorbidity in the Australian Genetics of Depression cohort study ( N = 13,839). Participants completed online questionnaires about chronic pain, psychiatric symptoms, comorbidities, treatment response and general health. Logistic regression mo…
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Psychology (21 obras) · Social Psychology (14 obras) · Biology (12 obras) · Developmental psychology (12 obras) · Genetics (12 obras) · Personality (11 obras) · Heritability (10 obras) · Genetic Associations and Epidemiology (9 obras) · Demography (8 obras) · Big Five personality traits (7 obras)