Igor Burstyn
Dados Biográficos
| ID | 5408974 |
|---|---|
| NOME | Igor Burstyn |
| PRENOMES | Igor |
| SOBRENOME | Burstyn |
| ASSINATURA | BURSTYN I |
| AFILIAÇÕES | Drexel University |
| ORCID | 0000-0002-7153-4478 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 19 |
| TOTAL DE CITAÇÕES | 4 |
| TOTAL COMO AUTOR | 19 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2010 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2024 |
| ÍNDICE H | 1 |
Excess risk of Covid-19 infection and mental distress in healthcare workers during successive pandemic waves
HCWs were at increased risk of both COVID-19 and mental ill-health with the excess risk continuing late in the pandemic
Further Improving Analysis of Date-Based Covid-19 Surveillance Data
It can be dangerous to take epidemic curves of Covid-19 at face value
Repeated Measures Regression in Laboratory, Clinical and Environmental Research
When using repeated measures linear regression models to make causal inference in laboratory, clinical and environmental research, it is typically assumed that the within-subject association of differences (or changes) in predictor variable values across replicates is the same as the between-subject association of differences in those predictor variable values. However, this is often false. For example, with body weight as the predictor variable …
What to Do When Accumulated Exposure Affects Health but Only Its Duration Was Measured? A Case of Linear Regression
Background : We considered a problem of inference in epidemiology when cumulative exposure is the true dose metric for disease, but investigators are only able to measure its duration on each subject. Methods : We undertook theoretical analysis of the problem in the context of a continuous response caused by cumulative exposure, when duration and intensity of exposure follow log-normal distributions, such that analysis by linear regression is nat…
Is Farm Milk a Risk Factor for Sarcoidosis? The Role of Farm Residence, Unpiped Water and Untreated Milk in Sarcoidosis
Objective : Sarcoidosis is thought to be an aberrant immune response to environmental agents, with rural living as a risk factor. We aimed to determine if farm living, consumption of farm (untreated) milk, or untreated water increased the risk of sarcoidosis. Methods: In a case-referent design, patients aged 18−60 with pulmonary sarcoidosis together with referents with other chronic respiratory disease, diagnosed 1999−2005 in Alberta, Canada, wer…
Pesticide Use and Asthma in Alberta Grain Farmers
A study of the respiratory health of grain farmers in Alberta, Canada was carried out in March 2002. Two populations were identified: members, in 1983, of a province-wide farm organisation, and grain farmers registered with the provincial agriculture department. A telephone interview addressed pesticide use (using pre-circulated trade names), chronic disease and respiratory symptoms. Pesticide ingredients were identified from provincial crop prot…
Drug use among men by sexual behaviour, race and ethnicity
A Simulation Study of Categorizing Continuous Exposure Variables Measured with Error in Autism Research
Variation in the odds ratio (OR) resulting from selection of cutoffs for categorizing continuous variables is rarely discussed. We present results for the effect of varying cutoffs used to categorize a mismeasured exposure in a simulated population in the context of autism spectrum disorders research. Simulated cohorts were created with three distinct exposure-outcome curves and three measurement error variances for the exposure. ORs were calcula…
The Role of Genotypes That Modify the Toxicity of Chemical Mutagens in the Risk for Myeloproliferative Neoplasms
Exposures, such as to aromatic compounds, whose toxicity is modified by genotypes associated with outcome in our analysis may play a role in the environmental etiology of MPNs
Pooling Bio-Specimens in the Presence of Measurement Error and Non-Linearity in Dose-Response
We sought to determine the potential effects of pooling on power, false positive rate (FPR), and bias of the estimated associations between hypothetical environmental exposures and dichotomous autism spectrum disorders (ASD) status. Simulated birth cohorts in which ASD outcome was assumed to have been ascertained with uncertainty were created. We investigated the impact on the power of the analysis (using logistic regression) to detect true assoc…
Effects of Non-Differential Exposure Misclassification on False Conclusions in Hypothesis-Generating Studies
Despite the theoretical success of obviating the need for hypothesis-generating studies, they live on in epidemiological practice. Cole asserted that "... there is boundless number of hypotheses that could be generated, nearly all of them wrong" and urged us to focus on evaluating "credibility of hypothesis". Adopting a Bayesian approach, we put this elegant logic into quantitative terms at the study planning stage for studies where the prior bel…
Toward Participatory Air Pollution Exposure Assessment in a Goods Movement Community
Progress in Community Health Partnerships: Research, Education, and Action - Volume 8, Issue 3, Fall 2014
Towards Participatory Air Pollution Exposure Assessment in a Goods Movement Community
Participation in personal air pollution monitoring and Photovoice exercises helped to increase awareness of pervasive mobile- and point-source diesel emissions throughout the neighborhood and develop priorities for action. Monitoring indicated the negative effects of cigarette smoke exposure, and disconnect between ambient- and personal-level PM2.5 concentrations that emphasized the need for more personal- and local-level monitoring. In addition,…
Quantifying the potential impact of measurement error in an investigation of autism spectrum disorder (ASD)
The Early Autism Risk Longitudinal Investigation (EARLI), an ongoing study of a risk-enriched pregnancy cohort, examines genetic and environmental risk factors for autism spectrum disorders (ASDs). We simulated the potential effects of both measurement error (ME) in exposures and misclassification of ASD-related phenotype (assessed as Autism Observation Scale for Infants (AOSI) scores) on measures of association generated under this study design.…
Maternal Exposure to Bisphenol-A and Fetal Growth Restriction
We conducted a case-referent study of the effect of exposure to bisphenol-A on fetal growth in utero in full-term, live-born singletons in Alberta, Canada. Newborns <10 percentile of expected weight for gestational age and sex were individually matched on sex, maternal smoking and maternal age to referents with weight appropriate to gestational age. Exposure of the fetus to bisphenol-A was estimated from maternal serum collected at 15-16 weeks of…
The Role of Maternal Smoking in Effect of Fetal Growth Restriction on Poor Scholastic Achievement in Elementary School
Fetal growth restriction and maternal smoking during pregnancy are independently implicated in lowering intellectual attainment in children. We hypothesized that only reduction of fetal growth that is attributable to extrinsic causes (e.g., maternal smoking) affects intellectual development of a child. Cross-sectional survey of 3,739 students in Nova Scotia (Canada) in 2003 was linked with the perinatal database, parental interviews on socio-demo…
Substance Use of Pregnant Women and Early Neonatal Morbidity
Second WCB Claims
Towards Participatory Air Pollution Exposure Assessment in a Goods Movement Community
Participation in personal air pollution monitoring and Photovoice exercises helped to increase awareness of pervasive mobile- and point-source diesel emissions throughout the neighborhood and develop priorities for action. Monitoring indicated the negative effects of cigarette smoke exposure, and disconnect between ambient- and personal-level PM2.5 concentrations that emphasized the need for more personal- and local-level monitoring. In addition,…
It can be dangerous to take epidemic curves of Covid-19 at face value
Second WCB Claims
Substance Use of Pregnant Women and Early Neonatal Morbidity
Second WCB Claims
The Role of Maternal Smoking in Effect of Fetal Growth Restriction on Poor Scholastic Achievement in Elementary School
Fetal growth restriction and maternal smoking during pregnancy are independently implicated in lowering intellectual attainment in children. We hypothesized that only reduction of fetal growth that is attributable to extrinsic causes (e.g., maternal smoking) affects intellectual development of a child. Cross-sectional survey of 3,739 students in Nova Scotia (Canada) in 2003 was linked with the perinatal database, parental interviews on socio-demo…
Maternal Exposure to Bisphenol-A and Fetal Growth Restriction
We conducted a case-referent study of the effect of exposure to bisphenol-A on fetal growth in utero in full-term, live-born singletons in Alberta, Canada. Newborns <10 percentile of expected weight for gestational age and sex were individually matched on sex, maternal smoking and maternal age to referents with weight appropriate to gestational age. Exposure of the fetus to bisphenol-A was estimated from maternal serum collected at 15-16 weeks of…
Effects of Non-Differential Exposure Misclassification on False Conclusions in Hypothesis-Generating Studies
Despite the theoretical success of obviating the need for hypothesis-generating studies, they live on in epidemiological practice. Cole asserted that "... there is boundless number of hypotheses that could be generated, nearly all of them wrong" and urged us to focus on evaluating "credibility of hypothesis". Adopting a Bayesian approach, we put this elegant logic into quantitative terms at the study planning stage for studies where the prior bel…
Toward Participatory Air Pollution Exposure Assessment in a Goods Movement Community
Progress in Community Health Partnerships: Research, Education, and Action - Volume 8, Issue 3, Fall 2014
Towards Participatory Air Pollution Exposure Assessment in a Goods Movement Community
Participation in personal air pollution monitoring and Photovoice exercises helped to increase awareness of pervasive mobile- and point-source diesel emissions throughout the neighborhood and develop priorities for action. Monitoring indicated the negative effects of cigarette smoke exposure, and disconnect between ambient- and personal-level PM2.5 concentrations that emphasized the need for more personal- and local-level monitoring. In addition,…
Quantifying the potential impact of measurement error in an investigation of autism spectrum disorder (ASD)
The Early Autism Risk Longitudinal Investigation (EARLI), an ongoing study of a risk-enriched pregnancy cohort, examines genetic and environmental risk factors for autism spectrum disorders (ASDs). We simulated the potential effects of both measurement error (ME) in exposures and misclassification of ASD-related phenotype (assessed as Autism Observation Scale for Infants (AOSI) scores) on measures of association generated under this study design.…
A Simulation Study of Categorizing Continuous Exposure Variables Measured with Error in Autism Research
Variation in the odds ratio (OR) resulting from selection of cutoffs for categorizing continuous variables is rarely discussed. We present results for the effect of varying cutoffs used to categorize a mismeasured exposure in a simulated population in the context of autism spectrum disorders research. Simulated cohorts were created with three distinct exposure-outcome curves and three measurement error variances for the exposure. ORs were calcula…
The Role of Genotypes That Modify the Toxicity of Chemical Mutagens in the Risk for Myeloproliferative Neoplasms
Exposures, such as to aromatic compounds, whose toxicity is modified by genotypes associated with outcome in our analysis may play a role in the environmental etiology of MPNs
Pooling Bio-Specimens in the Presence of Measurement Error and Non-Linearity in Dose-Response
We sought to determine the potential effects of pooling on power, false positive rate (FPR), and bias of the estimated associations between hypothetical environmental exposures and dichotomous autism spectrum disorders (ASD) status. Simulated birth cohorts in which ASD outcome was assumed to have been ascertained with uncertainty were created. We investigated the impact on the power of the analysis (using logistic regression) to detect true assoc…
Drug use among men by sexual behaviour, race and ethnicity
Is Farm Milk a Risk Factor for Sarcoidosis? The Role of Farm Residence, Unpiped Water and Untreated Milk in Sarcoidosis
Objective : Sarcoidosis is thought to be an aberrant immune response to environmental agents, with rural living as a risk factor. We aimed to determine if farm living, consumption of farm (untreated) milk, or untreated water increased the risk of sarcoidosis. Methods: In a case-referent design, patients aged 18−60 with pulmonary sarcoidosis together with referents with other chronic respiratory disease, diagnosed 1999−2005 in Alberta, Canada, wer…
Pesticide Use and Asthma in Alberta Grain Farmers
A study of the respiratory health of grain farmers in Alberta, Canada was carried out in March 2002. Two populations were identified: members, in 1983, of a province-wide farm organisation, and grain farmers registered with the provincial agriculture department. A telephone interview addressed pesticide use (using pre-circulated trade names), chronic disease and respiratory symptoms. Pesticide ingredients were identified from provincial crop prot…
Repeated Measures Regression in Laboratory, Clinical and Environmental Research
When using repeated measures linear regression models to make causal inference in laboratory, clinical and environmental research, it is typically assumed that the within-subject association of differences (or changes) in predictor variable values across replicates is the same as the between-subject association of differences in those predictor variable values. However, this is often false. For example, with body weight as the predictor variable …
What to Do When Accumulated Exposure Affects Health but Only Its Duration Was Measured? A Case of Linear Regression
Background : We considered a problem of inference in epidemiology when cumulative exposure is the true dose metric for disease, but investigators are only able to measure its duration on each subject. Methods : We undertook theoretical analysis of the problem in the context of a continuous response caused by cumulative exposure, when duration and intensity of exposure follow log-normal distributions, such that analysis by linear regression is nat…
It can be dangerous to take epidemic curves of Covid-19 at face value
Further Improving Analysis of Date-Based Covid-19 Surveillance Data
Excess risk of Covid-19 infection and mental distress in healthcare workers during successive pandemic waves
HCWs were at increased risk of both COVID-19 and mental ill-health with the excess risk continuing late in the pandemic
Medicine (16 obras) · Environmental health (10 obras) · Biology (8 obras) · Statistics (8 obras) · Demography (7 obras) · Mathematics (7 obras) · Demography (6 obras) · Logistic regression (6 obras) · Psychology (6 obras) · Econometrics (5 obras)