Paul E Croarkin
Dados Biográficos
| ID | 5422124 |
|---|---|
| NOME | Paul E Croarkin |
| PRENOMES | Paul E |
| SOBRENOME | Croarkin |
| ASSINATURA | CROARKIN P E |
| AFILIAÇÕES | WinnMed |
| ORCID | 0000-0001-6843-6503 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 13 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 13 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2011 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 0 |
Expert Rater Agreement for Symptoms and Diagnosis of Bipolar Disorder in Youth
Protest suicide
OPINION article Front. Psychiatry, 15 June 2023Sec. Public Mental Health Volume 14 - 2023 | https://doi.org/10.3389/fpsyt.2023.1213420
Evidence for machine learning guided early prediction of acute outcomes in the treatment of depressed children and adolescents with antidepressants
BACKGROUND: The treatment of depression in children and adolescents is a substantial public health challenge. This study examined artificial intelligence tools for the prediction of early outcomes in depressed children and adolescents treated with fluoxetine, duloxetine, or placebo. METHODS: The study samples included training datasets (N = 271) from patients with major depressive disorder (MDD) treated with fluoxetine and testing datasets from p…
Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder
BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms
Commentary
Nearly two in five youth with major depressive disorder fail to respond to first‐line interventions. As such, treatment‐resistant depression represents a formidable challenge for clinicians and researchers. In fact, even considering the diagnosis of treatment‐resistant depression in children and adolescents requires (a) defining treatment‐resistant depression and, by extension, treatment failure; (b) defining recovery; (c) understanding its devel…
Validation of Pictorial Mood Assessment with Ottawa Mood Scales and the Positive and Negative Affect Scale for Young Adults
Repetitive Transcranial Magnetic Stimulation in Youth With Treatment Resistant Major Depression
Background: Major depressive disorder (MDD) is common in youth and treatment options are limited. We evaluated the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in adolescents and transitional aged youth with treatment resistant MDD. Methods: Thirty-two outpatients with moderate to severe, treatment-resistant MDD, aged 13-21 years underwent a three-week, open-label, single center trial of rTMS (ClinicalTrials.gov…
Evidence Based Dyadic Therapies for 0- to 5-Year-Old Children With Emotional and Behavioral Difficulties
As many as one in four preschool-aged children are estimated to struggle with psychosocial stress and social-emotional issues; yet, interventions are often postponed until older ages when change is actually more difficult. Reasons for this include limited interventions, paucity of FDA approved medications for young children, as well as the dearth of clinicians adequately trained in psychotherapeutic approaches for young children. This commentary …
Parent-Child Interaction Therapy in a Case of Global Developmental Delay and Leukoencephalopathy
Parent-child interaction therapy (PCIT) is an evidence-based, behavioral dyadic treatment for caregivers and their children aged 2-7 years old with emotional and behavioral disorders. Here we present a treatment course of a 3-years-old girl with leukoencephalopathy, dysgenesis of the brainstem, and associated global developmental delay who was diagnosed with muscular dystrophy after PCIT completion. At the beginning of PCIT she had the developmen…
Paired-Associative Stimulation-Induced Long-term Potentiation-Like Motor Cortex Plasticity in Healthy Adolescents
PAS is a feasible, safe, and well-tolerated index of adolescent motor cortical plasticity. Gender may influence PAS-induced changes in cortical inhibition. PAS is safe and well tolerated by healthy adolescents and may be a novel tool with which to study adolescent neuroplasticity
Altered SPECT 123I-iomazenil Binding in the Cingulate Cortex of Children with Anorexia Nervosa
Several lines of evidence suggest that anxiety plays a key role in the development and maintenance of anorexia nervosa (AN) in children. The purpose of this study was to examine cortical GABA(A)-benzodiazepine receptor binding before and after treatment in children beginning intensive AN treatment. Brain single-photon emission computed tomography (SPECT) measurements using (123)I-iomazenil, which binds to GABA(A)-benzodiazepine receptors, was per…
Neurocognitive Effects of Repetitive Transcranial Magnetic Stimulation in Adolescents with Major Depressive Disorder
These preliminary findings suggest rTMS does not adversely impact neurocognitive functioning in adolescents and may provide subtle enhancement of verbal memory as measured by the CAVLT. Further controlled investigations with larger sample sizes and rigorous trial designs are warranted to confirm and extend these findings
Functional Connectivity of Brain Structures Correlates with Treatment Outcome in Major Depressive Disorder
Identifying biosignatures to assess the probability of response to an antidepressant for patients with major depressive disorder (MDD) is critically needed. Functional connectivity MRI (fcMRI) offers the promise to provide such a measure. Previous work with fcMRI demonstrated that the correlation in signal from one region to another is a measure of functional connectivity. In this pilot work, a baseline non-task fcMRI was acquired in 14 adults wi…
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Functional Connectivity of Brain Structures Correlates with Treatment Outcome in Major Depressive Disorder
Identifying biosignatures to assess the probability of response to an antidepressant for patients with major depressive disorder (MDD) is critically needed. Functional connectivity MRI (fcMRI) offers the promise to provide such a measure. Previous work with fcMRI demonstrated that the correlation in signal from one region to another is a measure of functional connectivity. In this pilot work, a baseline non-task fcMRI was acquired in 14 adults wi…
Neurocognitive Effects of Repetitive Transcranial Magnetic Stimulation in Adolescents with Major Depressive Disorder
These preliminary findings suggest rTMS does not adversely impact neurocognitive functioning in adolescents and may provide subtle enhancement of verbal memory as measured by the CAVLT. Further controlled investigations with larger sample sizes and rigorous trial designs are warranted to confirm and extend these findings
Altered SPECT 123I-iomazenil Binding in the Cingulate Cortex of Children with Anorexia Nervosa
Several lines of evidence suggest that anxiety plays a key role in the development and maintenance of anorexia nervosa (AN) in children. The purpose of this study was to examine cortical GABA(A)-benzodiazepine receptor binding before and after treatment in children beginning intensive AN treatment. Brain single-photon emission computed tomography (SPECT) measurements using (123)I-iomazenil, which binds to GABA(A)-benzodiazepine receptors, was per…
Paired-Associative Stimulation-Induced Long-term Potentiation-Like Motor Cortex Plasticity in Healthy Adolescents
PAS is a feasible, safe, and well-tolerated index of adolescent motor cortical plasticity. Gender may influence PAS-induced changes in cortical inhibition. PAS is safe and well tolerated by healthy adolescents and may be a novel tool with which to study adolescent neuroplasticity
Parent-Child Interaction Therapy in a Case of Global Developmental Delay and Leukoencephalopathy
Parent-child interaction therapy (PCIT) is an evidence-based, behavioral dyadic treatment for caregivers and their children aged 2-7 years old with emotional and behavioral disorders. Here we present a treatment course of a 3-years-old girl with leukoencephalopathy, dysgenesis of the brainstem, and associated global developmental delay who was diagnosed with muscular dystrophy after PCIT completion. At the beginning of PCIT she had the developmen…
Repetitive Transcranial Magnetic Stimulation in Youth With Treatment Resistant Major Depression
Background: Major depressive disorder (MDD) is common in youth and treatment options are limited. We evaluated the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in adolescents and transitional aged youth with treatment resistant MDD. Methods: Thirty-two outpatients with moderate to severe, treatment-resistant MDD, aged 13-21 years underwent a three-week, open-label, single center trial of rTMS (ClinicalTrials.gov…
Evidence Based Dyadic Therapies for 0- to 5-Year-Old Children With Emotional and Behavioral Difficulties
As many as one in four preschool-aged children are estimated to struggle with psychosocial stress and social-emotional issues; yet, interventions are often postponed until older ages when change is actually more difficult. Reasons for this include limited interventions, paucity of FDA approved medications for young children, as well as the dearth of clinicians adequately trained in psychotherapeutic approaches for young children. This commentary …
Commentary
Nearly two in five youth with major depressive disorder fail to respond to first‐line interventions. As such, treatment‐resistant depression represents a formidable challenge for clinicians and researchers. In fact, even considering the diagnosis of treatment‐resistant depression in children and adolescents requires (a) defining treatment‐resistant depression and, by extension, treatment failure; (b) defining recovery; (c) understanding its devel…
Validation of Pictorial Mood Assessment with Ottawa Mood Scales and the Positive and Negative Affect Scale for Young Adults
Evidence for machine learning guided early prediction of acute outcomes in the treatment of depressed children and adolescents with antidepressants
BACKGROUND: The treatment of depression in children and adolescents is a substantial public health challenge. This study examined artificial intelligence tools for the prediction of early outcomes in depressed children and adolescents treated with fluoxetine, duloxetine, or placebo. METHODS: The study samples included training datasets (N = 271) from patients with major depressive disorder (MDD) treated with fluoxetine and testing datasets from p…
Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder
BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms
Protest suicide
OPINION article Front. Psychiatry, 15 June 2023Sec. Public Mental Health Volume 14 - 2023 | https://doi.org/10.3389/fpsyt.2023.1213420
Expert Rater Agreement for Symptoms and Diagnosis of Bipolar Disorder in Youth
Psychology (12 obras) · Medicine (11 obras) · Psychiatry (11 obras) · Clinical Psychology (6 obras) · Internal Medicine (6 obras) · Mood (6 obras) · Clinical Psychology (5 obras) · Major depressive disorder (4 obras) · Antidepressant (3 obras) · Child and Adolescent Psychosocial and Emotional Development (3 obras)