Keith M Godfrey
Dados Biográficos
| ID | 5459800 |
|---|---|
| NOME | Keith M Godfrey |
| PRENOMES | Keith M |
| SOBRENOME | Godfrey |
| ASSINATURA | GODFREY K M |
| AFILIAÇÕES | University Hospital Southampton NHS Foundation Trust |
| ORCID | 0000-0003-3025-5269 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 52 |
| TOTAL DE CITAÇÕES | 26 |
| TOTAL COMO AUTOR | 52 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1993 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 3 |
Protocol of the Temporality, Eating and Metabolic health during PreconceptiOn (Tempo) study in females with overweight and obesity
Preconception to postpartum accelerometry-based 24-hour movement behaviors
ClinicalTrials.gov, NCT03531658 (registered May 22, 2018)
The Association Between Maternal Adiposity and Breastfeeding Initiation and Duration
In this study maternal adiposity had little impact on breastfeeding initiation but higher maternal adiposity was associated with shorter breastfeeding duration. This study suggests that more support should be given to mothers with overweight and obesity to promote longer duration of breastfeeding
Feeding practices and concerns as mediators between maternal mental health and eating behaviours in early childhood
BACKGROUND: The impact of maternal mental health on child eating beyond infancy is understudied. This study explores whether maternal feeding practices and concerns mediate the association between maternal depression and anxiety symptoms and eating behaviours at age three years. METHODS: Data from 409 mother-child dyads in the Growing Up in Singapore Towards healthy Outcomes cohort were analysed. Maternal mental health was assessed using the Beck…
The prospective associations of 24-hour movement behaviors and domain-specific activities with executive function and academic achievement among school-aged children in Singapore
Background Physical activity (PA), sedentary behavior (SB), and sleep are collectively referred to as 24-h movement behaviors, which may be linked to cognitive development in children. However, most of the evidence was based on cross-sectional studies and/or solely relied on parent-reported information on children’s behaviors, and it remains uncertain whether all domains/contexts of PA and SB are similarly associated with executive function and a…
ImpEnsa eHealthy Conversation Skills training for healthcare professionals aimed at improving micronutrient status during the first 1000 days in South Africa
Individuals’ lifestyle behaviours determine health. Improving Early Nutrition and Health in South Africa (“ImpENSA”), an EU Erasmus+ co-funded project, aims to tackle the triple burden of malnutrition in South Africa through equipping healthcare professionals (HCPs) with knowledge and skills to effectively support healthy nutritional choices among pregnant women and mothers/infant caregivers. Healthy Conversation Skills (HCS) is a behaviour chang…
Feasibility Testing of a Health Literacy Intervention With Adolescents and Young Adults in South Africa
INTRODUCTION: Low health literacy levels during adolescence and young adulthood (AYA) may impact acute healthcare access and longer-term health outcomes. Previous research in South African AYA suggests that health literacy levels are typically suboptimal but few interventions exist. This study aimed to test the acceptability and feasibility of a co-created, interactive health literacy intervention (LifeLab-Soweto) with AYA in Soweto, South Africa…
What Does ‘Preconception Health’ Mean to People? A Public Consultation on Awareness and Use of Language
INTRODUCTION: There is growing scientific and policy recognition that optimising health before a potential pregnancy (preconception health) improves reproductive outcomes and the lifelong health of future children. However, public awareness on this topic is low. We conducted a public consultation to develop language recommendations and identify and prioritise approaches to inform research and improve public awareness of preconception health. METH…
Evaluation of ImpEnsa technology‐enabled behaviour change module delivered to healthcare professionals in South Africa to improve micronutrient nutrition during the first 1000 days
Healthcare professionals (HCPs) have vital roles in providing evidence-based care to promote healthy micronutrient nutrition in early life. Providing such care requires scalable training to strengthen knowledge and confident application of effective behaviour change skills. Among 33 public and private HCPs (primarily dietitians) in South Africa, we evaluated the behaviour change aspects of a technology-enabled National Qualification Sub-Framework…
Correlates of lifestyle patterns among children in Singapore aged 10 years
These findings provide direction for future interventions by identifying vulnerable groups and contexts that should be prioritised
Relation of preconception eating behaviours to dietary pattern trajectories and gestational weight gain from preconception to late pregnancy
What values drive communities’ nutrition priorities in a resource constrained urban area in South Africa
Our study demonstrates how public engagement can facilitate the incorporation of community values and programmatic preferences into nutrition priority setting, enabling a responsive approach to local community needs, especially in resource constrained contexts. Findings could guide policy makers to facilitate more appropriate decisions and to improve nutrition in the first 1000 days of life
Children born during the hunger season are at a higher risk of severe acute malnutrition
Heightened food insecurity in the hunger season increases the risk of severe acute malnutrition (SAM) in childhood. This study examined the association of season of birth with SAM in a Guinean Sahelian ecological zone. We analyzed routine health and sociodemographic surveillance data from the Navrongo Health and Socio-demographic Surveillance System collected between 2011 and 2018. January-June, the period of highest food insecurity, was defined …
Automated Machine Learning (AutoML)-Derived Preconception Predictive Risk Model to Guide Early Intervention for Gestational Diabetes Mellitus
The increasing prevalence of gestational diabetes mellitus (GDM) is contributing to the rising global burden of type 2 diabetes (T2D) and intergenerational cycle of chronic metabolic disorders. Primary lifestyle interventions to manage GDM, including second trimester dietary and exercise guidance, have met with limited success due to late implementation, poor adherence and generic guidelines. In this study, we aimed to build a preconception-based…
How do we engage people in testing for Covid-19? A rapid qualitative evaluation of a testing programme in schools, GP surgeries and a university
Participants' and stakeholders' motivations, challenges and concerns need to be understood and these insights used to modify the programme in a continuous, real-time process to ensure and sustain engagement with testing over the extended period necessary. Community leaders and stakeholder organisations should be involved throughout programme development and implementation to optimise engagement
Associations of Childcare Arrangements with Adiposity Measures in a Multi-Ethnic Asian Cohort
Childcare arrangements shape behavioural patterns that influence the risk of childhood obesity. However, little is known of its influence on childhood obesity in Singapore. We aim to examine the associations between childcare arrangements at the age of 5 years and childhood adiposity at age 6 years. Children from the GUSTO study were grouped into three childcare arrangements at age 5: full-time centre-based childcare (FC), partial centre-based wi…
Community perspectives on maternal and child health during nutrition and economic transition in sub-Saharan Africa
Objective: To explore community perceptions on maternal and child nutrition issues in Sub-Saharan Africa. Design: Thirty focus groups with men and women from three communities facilitated by local researchers. Setting: One urban (Soweto, South Africa) and two rural settings (Navrongo, Ghana and Nanoro, Burkina Faso) at different stages of economic transition. Participants: Two hundred thirty-seven men and women aged 18–55 years, mostly subsistenc…
Identification and reproducibility of dietary patterns assessed with a FFQ among women planning pregnancy
Objective: To identify a posteriori dietary patterns among women planning pregnancy and assess the reproducibility of these patterns in a subsample using two dietary assessment methods. Design: A semi-quantitative FFQ was administered to women enrolled in the Singapore PREconception Study of long-Term maternal and child Outcomes study. Dietary patterns from the FFQ were identified using exploratory factor analysis (EFA). In a subsample of women (…
Does early introduction of solid feeding lead to early cessation of breastfeeding
Mixed milk feeding increases the likelihood of breastfeeding cessation, but it is not known if solid feeding (SF) has the same effect. We have identified 10,407 infants breastfed for at least 8-10 weeks from three large U.K. studies (Avon Longitudinal Study of Parents and Children [ALSPAC; born 1990-1991], Southampton Woman's Survey [SWS; 1998-2008], and Infant Feeding Survey 2010 [IFS 2010]) to investigate the associations between early SF and b…
The Effects of Different Smoking Patterns in Pregnancy on Perinatal Outcomes in the Southampton Women’s Survey
Maternal smoking during pregnancy has established associations with poor perinatal outcomes. Among continuing pregnant smokers, harm-reduction strategies have been suggested, including temporary cessation of smoking during pregnancy, also known as partial quitting. Support for this strategy, however, remains limited. Six hundred and ninety-seven women in the Southampton Women's Survey who smoked at their last menstrual period were categorised int…
Fetal growth does not modify the relationship of infant weight gain with childhood adiposity and blood pressure in the Southampton women’s survey
Background: Rapid infant weight gain is a risk factor for childhood obesity. This relationship may depend on whether infant weight gain is preceded by in-utero growth restriction. Aim : Examine whether fetal growth modifies the relationship between infant weight gain and childhood adiposity and blood pressure. Subjects and methods: 786 children in the Southampton Women's Survey. We related infant weight gain (weight at 2 years-birth weight) to bo…
Is breastfeeding associated with later child eating behaviours
Iron status and risk factors of iron deficiency among pregnant women in Singapore
NCT01174875 . Registered 1 July 2010 (retrospectively registered)
Validation of a semi-quantitative FFQ for 18-month-old toddlers
Objective Dietary intake of toddlers has been of growing interest due to its long-term consequences on health. However, previous works have focused largely on Caucasian populations and less is known about Asian toddlers. We aimed to validate a semi-quantitative FFQ designed to assess dietary intakes of 18-month-old toddlers in a multi-ethnic Asian cohort. Design An FFQ of ninety-four food items, identified based on food records of 12-month-old GU…
Maternal feeding practices and children's food intake during an ad libitum buffet meal
Validation of the Children's Eating Behavior Questionnaire in 3 year old children of a multi-ethnic Asian population
Oral processing behaviours that promote children's energy intake are associated with parent-reported appetitive traits
Maternal feeding practices and children's food intake during an ad libitum buffet meal
Midlife reversibility of early-established biobehavioral risk factors
Objectives: Epidemiological evidence links exposure to early life adversities --such as childhood maltreatment-- with impaired health and wellbeing in adulthood. Since these effects are usually unrecognized or untreated in childhood, preventive and remediating interventions in adults are needed. We asked, first, can we validly ascertain childhood adversity through retrospective assessments in adulthood? Second, what dimensions of childhood advers…
Does living in a food insecure household impact on the diets and body composition of young children? Findings from the Southampton Women's Survey
BACKGROUND: Little is known about food insecurity in the UK. The aims of this study were to assess the prevalence and factors associated with food insecurity in a UK cohort and to examine whether the diets, reported health and anthropometry of young food insecure children differed from those of other children. METHODS: The Southampton Women's Survey is a prospective cohort study in which detailed information about the diets, lifestyle and body co…
Relation of preconception eating behaviours to dietary pattern trajectories and gestational weight gain from preconception to late pregnancy
Is breastfeeding associated with later child eating behaviours
Body size and body composition
BACKGROUND: Indian babies are characterised by the 'thin-fat phenotype' which comprises a 'muscle-thin but adipose' body composition compared with European babies. This body phenotype is of concern because it is associated with an increased risk of diabetes and cardiovascular disease. We examined whether the 'thin-fat phenotype' persists through early childhood, comparing Indian children with white Caucasians in the UK at birth, infancy and child…
Fetal nutrition and cardiovascular disease in adult life
Fetal nutrition and adult disease
Fetal programming and adult health
Low birthweight is now known to be associated with increased rates of coronary heart disease and the related disorders stroke, hypertension and non-insulin dependent diabetes. These associations have been extensively replicated in studies in different countries and are not the result of confounding variables. They extend across the normal range of birthweight and depend on lower birthweights in relation to the duration of gestation rather than th…
Developmental plasticity and human health
What do babies eat? Evaluation of a food frequency questionnaire to assess the diets of infants aged 6 months
Objective To evaluate the relative validity of a food frequency questionnaire (FFQ) for assessing nutrient intakes in 6-month-old infants. Design and setting The FFQ was developed to assess the diets of infants born to women in the Southampton Women’s Survey (SWS), a population-based survey of young women and their offspring. The energy and nutrient intakes obtained from an interviewer-administered FFQ were compared with those obtained from a 4-d…
A longitudinal study of blood folate levels and depressive symptoms among young women in the Southampton Women’s Survey
BACKGROUND: Lower blood folate levels have been associated with depression in cross-sectional surveys, but no studies have examined the relationship prospectively to determine whether the relationship is causal. A follow-up study was designed to examine whether lower blood folate levels predict incident depressive symptoms. METHOD: Women aged 20-34 years registered in general practices in Southampton, UK, were asked to participate. Baseline asses…
What do babies eat? Evaluation of a food frequency questionnaire to assess the diets of infants aged 12 months
Objective To evaluate the relative validity of an FFQ for assessing nutrient intakes in 12-month-old infants. Design and setting The FFQ was developed to assess the diets of infants born to women in the Southampton Women’s Survey (SWS), a population-based survey of young women and their offspring. The energy and nutrient intakes obtained from an interviewer-administered FFQ were compared with those obtained from 4d weighed diaries (WD). Subjects …
Breastfeeding and reported morbidity during infancy
A number of studies in developed countries suggest that breastfeeding protects against infections in infancy. However, the choice to breastfeed is often related to maternal characteristics, and many of these studies are limited in the extent to which they can take account of confounding influences. In a prospective birth cohort study, we assessed the relationship between the duration of breastfeeding and the prevalence of lower respiratory tract …
Does a heavy baby become a strong child? Grip strength at 4 years in relation to birthweight
Objective Consistent positive relationships have been found between birthweight and grip strength in young, middle-aged and older adults, suggesting that early influences on the growth and development of muscle are important for muscle function later in the lifecourse. However there are limited data in children. We aimed to assess the relationship between birthweight and grip strength in children aged 4 years. Design Prospective general populatio…
P1-179 The Southampton women's survey
Introduction Epidemiological studies inform understanding of influences on health. Findings can lead directly to policy changes, but such changes need assessing, using formal intervention studies. Methods The Southampton Women's Survey is a longitudinal birth cohort with data collected on the mothers before conception. 12 583 women aged 20–34 years were assessed when not pregnant; 3159 were then followed through pregnancy and the children are fol…
Does living in a food insecure household impact on the diets and body composition of young children? Findings from the Southampton Women's Survey
BACKGROUND: Little is known about food insecurity in the UK. The aims of this study were to assess the prevalence and factors associated with food insecurity in a UK cohort and to examine whether the diets, reported health and anthropometry of young food insecure children differed from those of other children. METHODS: The Southampton Women's Survey is a prospective cohort study in which detailed information about the diets, lifestyle and body co…
Maternal awareness of young children’s physical activity
Almost 90% of mothers of inactive preschool-aged children perceive their child to be active. Nursery-school attendance and having older siblings at home may be important to consider when designing behavioural interventions to increase PA in preschool children
Dietary changes during pregnancy and the postpartum period in Singaporean Chinese, Malay and Indian women
Objective To examine changes in food consumption during pregnancy and the postpartum period in women of major Asian ethnic groups. Design Using interviewer-administered questionnaires, we assessed changes in food consumption during pregnancy (26–28 weeks’ gestation) and the postpartum period (3 weeks after delivery) as compared with the usual pre-pregnancy diet. Setting Singapore. Subjects Pregnant women ( n 1027) of Chinese, Malay and Indian eth…
Assessing diets of 3-year-old children
Objective To evaluate the use of an administered eighty-item FFQ to assess nutrient intake and diet quality in 3-year-old children. Design Frequency of consumption and portion size of the foods listed on the FFQ during the 3 months preceding the interview were reported by the child's main caregiver; after the interview a 2 d prospective food diary (FD) was completed on behalf of the child. Nutrient intakes from the FFQ and FD were estimated using…
Physical Activity and Sedentary Behavior Patterns Before and During Pregnancy in a Multi-ethnic Sample of Asian Women in Singapore
Tobacco smoke exposure and respiratory morbidity in young children
Secondhand smoke exposure during the prenatal and postnatal periods is associated with increased respiratory morbidity in children. Opportunistic screening and targeted smoking cessation counselling for parents at child hospital admissions and well-child outpatient visits, as well as preconception smoking cessation counselling for future pregnancies, may be beneficial to protect the child from negative health impacts
Body size and body composition
BACKGROUND: Indian babies are characterised by the 'thin-fat phenotype' which comprises a 'muscle-thin but adipose' body composition compared with European babies. This body phenotype is of concern because it is associated with an increased risk of diabetes and cardiovascular disease. We examined whether the 'thin-fat phenotype' persists through early childhood, comparing Indian children with white Caucasians in the UK at birth, infancy and child…
Nausea and vomiting in early pregnancy
Experiences of nausea and/or vomiting in pregnancy (NVP) vary greatly, but the paucity of studies with pre-pregnancy dietary data mean that little is known about the effects of NVP on diet. Using an administered food frequency questionnaire, diet was assessed before pregnancy and at 11 and 34 weeks' gestation in 2270 participants in a UK birth cohort study (Southampton Women's Survey). Experience of NVP in early pregnancy was graded as none, mild…
Maternal and infant correlates of maternal feeding beliefs and practices in a multi-ethnic Asian population
Objective Little is known about the influences of maternal and infant correlates on maternal feeding beliefs and practices in the first 2 years of life, despite its important role in early obesogenic eating behaviours and weight gain. Design Cross-sectional study using demographic data of mothers and infants obtained at 26–28 weeks of gestation, and postnatally from birth to 15 months, respectively. The Infant Feeding Questionnaire was administer…
Sleep and Dietary Patterns in Pregnancy
Evidence on the association between sleep, diet, and eating behaviors in pregnant women is lacking. We examine this in a cohort of apparently healthy pregnant women. At 26-28 weeks gestation, 497 participants completed the Pittsburgh Sleep Quality Index to assess sleep and a 24-h recall to assess dietary intake. Diet quality was assessed by the Healthy Eating Index for pregnant women in Singapore (HEI-SGP) score and previously derived dietary pat…
Greater access to healthy food outlets in the home and school environment is associated with better dietary quality in young children
Objective To explore associations between dietary quality and access to different types of food outlets around both home and school in primary school-aged children. Design Cross-sectional observational study. Setting Hampshire, UK. Subjects Children ( n 1173) in the Southampton Women’s Survey underwent dietary assessment at age 6 years by FFQ and a standardised diet quality score was calculated. An activity space around each child’s home and scho…
Validation of the Children's Eating Behavior Questionnaire in 3 year old children of a multi-ethnic Asian population
Prospective associations between parental feeding practices and children's oral processing behaviours
Previous research demonstrated that faster eating rates are linked with increased intake of energy during a meal. Here, we examined whether within-meal parental feeding practices show cross-sectional and prospective associations with children's oral processing behaviours and whether the previously demonstrated association between faster eating rates and higher energy intakes varies by parental feeding practices. A subset (n = 155) of children and…
Pregnancy Trimester-Specific Exposure to Ambient Air Pollution and Child Respiratory Health Outcomes in the First 2 Years of Life
Prenatal exposure to air pollution is associated with childhood respiratory health; however, no previous studies have examined maternal pre-pregnancy body mass index (BMI) as a potential effect modifier. We investigated whether maternal pre-pregnancy BMI modified the association of trimester-specific air pollution divided into quartiles of exposure (Q1−4) on respiratory health in the Growing Up in Singapore towards healthy Outcomes (GUSTO) study …
Food Sources of Energy and Macronutrient Intakes among Infants from 6 to 12 Months of Age
Adequate nutrition during complementary feeding is important for the growth, development and well-being of children. We aim to examine the energy and macronutrient intake composition and their main food sources in a mother-offspring cohort study in Singapore. The diets of infants were assessed by 24 h dietary recalls or food diaries collected from mothers when their offspring were 6 (n = 760), 9 (n = 893) and 12 (n = 907) months of age. Food sour…
Medicine (46 obras) · Obesity, Physical Activity, Diet (26 obras) · Demography (22 obras) · Environmental health (21 obras) · Pregnancy (21 obras) · Internal Medicine (18 obras) · Pediatrics (18 obras) · Biology (15 obras) · Cohort (15 obras) · Demography (15 obras)