Barbra A Richardson
Dados Biográficos
| ID | 5488058 |
|---|---|
| NOME | Barbra A Richardson |
| PRENOMES | Barbra A |
| SOBRENOME | Richardson |
| ASSINATURA | RICHARDSON B A |
| AFILIAÇÕES | University of Washington |
| ORCID | 0000-0001-9564-1828 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 37 |
| TOTAL DE CITAÇÕES | 10 |
| TOTAL COMO AUTOR | 37 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1991 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 2 |
Indoor and outdoor fine particulate matter and carbon monoxide concentrations in homes of infants in Nairobi, Kenya
Early life exposure to air pollution is associated with adverse health outcomes in children however few studies have investigated children’s air pollution exposures in urban settings in sub-Saharan Africa (SSA). We measured fine particulate matter (PM 2.5 ) and carbon monoxide (CO) in homes of infants in Nairobi, Kenya and conducted exploratory analysis of exposure factors. Questionnaires captured household characteristics and self-reported air p…
Assessing the approach to perinatal mental health screening and treatment in maternal-child health clinics in Western Kenya
Integrating mental health care into well-attended health services, such as maternal-child health (MCH), offers a promising approach to increasing access to mental health care. To inform integration, we assessed the current approach to screening and treatment of perinatal mood and anxiety disorders (PMAD) in MCH facilities in Western Kenya. We conducted a cross-sectional survey among the facility managers (“in-charges”) at 20 MCH facilities in Wes…
Evaluating the safety of prenatal HIV PrEP use
Existing data support the safety of daily oral tenofovir disoproxil fumarate (TDF)-based HIV pre-exposure prophylaxis (PrEP) use in pregnancy, yet ongoing monitoring is needed. We analyzed data from three recently completed HIV PrEP safety and implementation studies (PrIMA, PrIMA-X, and mWACh-PrEP) that enrolled women who were offered and/or initiated TDF-based HIV PrEP at routine health clinics in Western Kenya to summarize perinatal outcomes fo…
Effect of azithromycin on post-discharge growth in Kenyan children
INTRODUCTION: Children discharged following hospitalisation for acute illnesses in low- and middle-income settings are at increased risk of poor growth, particularly linear growth faltering. We aimed to determine the effect of azithromycin administered at hospital discharge on post-discharge growth. METHODS: Using data from the Toto Bora Trial (NCT02414399), a double-blind, placebo-controlled randomised trial of a 5-day course of azithromycin in …
Educational attainment and self-reported environmental exposures of pregnant women living in Nairobi, Kenya
Environmental exposures experienced by pregnant women living in cities of low- and middle-income countries are poorly described. We collected information on housing characteristics, household and ambient air pollution, and work-related exposures through questionnaires in a cohort of 400 pregnant women in Nairobi, Kenya and examined exposures in relation to educational attainment, a proxy for socioeconomic status. Participants were median 26 years…
Cross-sectional study evaluating organizational climate, change commitment, and change efficacy for predicting family planning clinics’ success in increasing HIV counseling and testing in Mombasa, Ken…
Increasing HIV testing and counselling (HTC) is a first step to reducing HIV transmission. Implementing HTC in family planning (FP) clinics has been proposed to increase HIV testing coverage in at-risk populations. The Systems Analysis and Improvement Approach (SAIA) was used to improve HTC rates in FP clinics in Mombasa, Kenya. This hypothesis-generating exploratory analysis evaluated the associations between organizational climate characteristi…
Acceptability of the dapivirine vaginal ring for HIV-1 prevention among women reporting engagement in transactional sex
We assessed if acceptability of the dapivirine vaginal ring for HIV prevention differed among the subgroup of women who reported engaging in transactional sex prior to enrollment in MTN-020/ASPIRE (phase III trial in Malawi, South Africa, Uganda, and Zimbabwe, 2012-2015; n = 2629). Transactional sex was defined as receipt of money, goods, gifts, drugs, or shelter in exchange for sex in the past year. Dimensions of acceptability included: ease of …
Efficacy of the Dapivirine Vaginal Ring Accounting for Imperfect Adherence
Adolescent experiences, perceptions, and preferences for the process of HIV status disclosure in Kenya
Introduction: Disclosure of HIV status to adolescents living with HIV has been associated with improved treatment outcomes. However, there are limited data regarding the experiences of, perceptions of, and preferences for the process of disclosure of HIV status among adolescents and young adults living with HIV (AYLH), especially in sub-Saharan Africa. Methods: Young adults living with HIV from 20 HIV clinics in Kenya who participated in a clinic…
Simulated patient training to improve youth engagement in HIV care in Kenya
Youth living with HIV (YLHIV) report that negative interactions with health care workers (HCWs) affects willingness to return to care. This stepped wedge randomized trial evaluated effectiveness of a standardized patient actor (SP) HCW training intervention on adolescent engagement in care in Kenya. HCWs caring for YLHIV at 24 clinics received training on adolescent care, values clarification, communication, and motivational interviewing, with 7 …
Impact of the Covid-19 pandemic on obstetrical care at a tertiary care facility in Mombasa, Kenya
The COVID-19 pandemic caused disruption in healthcare delivery due to reductions in both health facility capacity and care-seeking behavior. For women experiencing obstetric complications, access to comprehensive emergency obstetric care is critical for maternal and child health. In Kenya, pandemic-related restrictions began in March 2020 and were compounded by a healthcare worker strike in December 2020. We examined medical record data at Coast …
Randomized controlled trial of a theory-informed mHealth intervention to support ART adherence and viral suppression among women with HIV in Mombasa, Kenya
This trial was registered with ClinicalTrials.gov (NCT02627365, 10/12/2015; http://clinicaltrials.gov )
Fertility Desire and Associations with Condomless Sex, Antiretroviral Adherence, and Transmission Potential in a Cohort of Kenyan Women Living with HIV in Sero-discordant Relationships
For women living with HIV (WLH) in serodiscordant partnerships, decisions about childbearing can challenge condom use and antiretroviral adherence. In a prospective cohort of 148 WLH in serodiscordant partnerships, 58 (39%) wanted more children in the future but were not currently trying to conceive (fertility desire), and 32 (22%) were currently trying to become pregnant (fertility intent). Detection of prostate specific antigen (PSA) in vaginal…
Antenatal depressive symptoms in Kenyan women living with HIV
Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) in six Kenyan public maternal and child health clinics. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), stigma with the Stigma Scale for Chronic Illness, and intimate partner violence (IPV)…
The Impact of a Comic Book Intervention on East African-American Adolescents’ HPV Vaccine-Related Knowledge, Beliefs and Intentions
A Prospective Study of Depressive Symptoms, Condomless Sex, and HIV Viral Load in HIV-Positive Female Sex Workers in Kenya
Derivation of an HIV Risk Score for African Women Who Engage in Sex Work
Newly diagnosed HIV positive children
Newly diagnosed HIV positive children may be unique index cases to identify undiagnosed parents. Data was used from the Pediatric Urgent Start of HAART (NCT02063880) trial, which enrolled hospitalized, ART-naïve, HIV positive children ages 0–12 years in Kenya. Exact McNemar’s tests were used to compare proportions of mothers and fathers tested for HIV, linked to care, and on ART at baseline and 6 months. This analysis included 87 newly diagnosed …
Psychosocial Factors, Condomless Sex, and Detectable Viral Load in HIV-Positive Women in Serodiscordant Couples in Nairobi, Kenya
Trajectory of use over time of an oral tablet and a rectal gel for HIV prevention among transgender women and men who have sex with men
We examined product adherence among 187 men who have sex with men and transgender women enrolled in a phase II, crossover trial comparing safety and acceptability of an oral tablet and a rectal gel used daily for HIV prevention. Participants reported adherence via daily text messages during 8-week periods. Trajectory analysis identified weekly patterns. Polytomous logistic regression identified characteristics associated with higher probability o…
Pilot evaluation of a standardized patient actor training intervention to improve HIV care for adolescents and young adults in Kenya
Poor retention in HIV care remains a major problem for Adolescents and Young Adults (AYA). A Standardized Patient (SP) clinical training intervention was developed to improve healthcare worker (HCW) "adolescent-friendly" competencies in Kenya. Professional actors were trained to portray HIV-infected AYA according to standardized scripts. HCWs completed a 2-day SP training that included didactic sessions, 7 video-recorded SP encounters, and group …
Birth size and early pneumonia predict linear growth among HIV‐exposed uninfected infants
Stunting remains a global health priority, particularly in sub-Saharan Africa. Identifying determinants of linear growth in HIV-exposed uninfected (HEU) infants can inform interventions to prevent stunting in this vulnerable population. HIV-infected mothers and their uninfected infants were followed monthly from pregnancy to 12-month post-partum in Nairobi, Kenya. Mixed-effects models estimated the change in length-for-age z-score (LAZ) from birt…
A Mixed-Methods Study Examining Adherence to and Acceptability of Intravaginal Rings for HIV Prevention
Vaginal Ring Use in a Phase 3 Microbicide Trial
Alcohol use and immune reconstitution among HIV-infected patients on antiretroviral therapy in Nairobi, Kenya
Studies on the effects of alcohol use on HIV disease progression have been contradictory, with at least one study finding a positive effect of low alcohol consumption on CD4 count. In addition, most such studies have taken place in the developed West. We investigated the association between alcohol use and immune reconstitution through CD4 count response among HIV-infected individuals on antiretroviral therapy (ART) at an urban sub-Saharan Africa…
Number of Siblings and Sociability
Race/ethnicity patterns in the homicide of children in Los Angeles, 1980 through 1989
This study investigated age, sex, and race/ethnicity risk patterns for homicide based on 246 children (newborn to 14 years old) who were murdered in the city of Los Angeles 1980 through 1989. Rates of homicide are higher for newborn to 4-year-olds than for 5- to 14-year-olds. Boys and girls have similar rates of homicide at young ages; among 5- to 14-year-olds, however, boys have higher rates. Characteristics of the victim, suspect, and event wer…
Number of Siblings and Sociability
Race/ethnicity patterns in the homicide of children in Los Angeles, 1980 through 1989
This study investigated age, sex, and race/ethnicity risk patterns for homicide based on 246 children (newborn to 14 years old) who were murdered in the city of Los Angeles 1980 through 1989. Rates of homicide are higher for newborn to 4-year-olds than for 5- to 14-year-olds. Boys and girls have similar rates of homicide at young ages; among 5- to 14-year-olds, however, boys have higher rates. Characteristics of the victim, suspect, and event wer…
Antenatal Couple Counseling Increases Uptake of Interventions to Prevent HIV-1 Transmission
To determine effect of partner involvement and couple counseling on uptake of interventions to prevent HIV-1 transmission, women attending a Nairobi antenatal clinic were encouraged to return with partners for voluntary HIV-1 counseling and testing (VCT) and offered individual or couple posttest counseling. Nevirapine was provided to HIV-1-seropositive women and condoms distributed to all participants. Among 2104 women accepting testing, 308 (15%…
The consequences of post-election violence on antiretroviral HIV therapy in Kenya
Over 1000 individuals were killed and 600,000 were displaced during post-election violence (PEV) in Kenya in 2008. Antiretroviral therapy (ART) depends on continuous access to medications which may have been interrupted due to PEV. In a mixed-methods retrospective review, treatment interruption of ART during PEV was measured among 2534 HIV-positive adults attending the Coptic Hope Center for Infectious Diseases in Nairobi, Kenya. Clients experien…
Prevalence and correlates of insecticide-treated bednet use among HIV-1-infected adults in Kenya
HIV-1-infected adults are at increased risk for malaria. Insecticide-treated bednets protect individuals from malaria. Little is known about correlates of ownership and use of bednets among HIV-1-infected individuals. We conducted a cross-sectional survey of 388 HIV-1-infected adults recruited from three sites in Kenya (Kilifi, Kisii, and Kisumu) to determine factors associated with ownership and use of optimal bednets. We defined an optimal bedn…
Adherence and Acceptability in MTN 001
Prevalence, perceptions, and correlates of pediatric HIV disclosure in an HIV treatment program in Kenya
Disclosure to HIV-infected children regarding their diagnosis is important as expanding numbers of HIV-infected children attain adolescence and may become sexually active. In order to define correlates of pediatric disclosure and facilitate development of models for disclosure, we conducted a cross-sectional survey of primary caregivers of HIV-1 infected children aged 6-16 years attending a pediatric HIV treatment program in Nairobi, Kenya. We co…
Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women
BACKGROUND: Reproductive-age women need effective interventions to prevent the acquisition of human immunodeficiency virus type 1 (HIV-1) infection. METHODS: We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir-emtricitabine (TDF-FTC), or 1% tenofovir (TFV) vaginal gel as preexposure prophylaxis against HIV-1 infection in women in South Africa, Uganda, and Zimb…
Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women
BACKGROUND: Antiretroviral medications that are used as prophylaxis can prevent acquisition of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials among African women, the incidence of HIV-1 infection was not reduced, probably because of low adherence. Longer-acting methods of drug delivery, such as vaginal rings, may simplify use of antiretroviral medications and provide HIV-1 protection. METHODS: We conducted a ph…
A Prospective Cohort Study of Intimate Partner Violence and Unprotected Sex in HIV-Positive Female Sex Workers in Mombasa, Kenya
A Prospective Study of Intimate Partner Violence as a Risk Factor for Detectable Plasma Viral Load in HIV-Positive Women Engaged in Transactional Sex in Mombasa, Kenya
Alcohol use and immune reconstitution among HIV-infected patients on antiretroviral therapy in Nairobi, Kenya
Studies on the effects of alcohol use on HIV disease progression have been contradictory, with at least one study finding a positive effect of low alcohol consumption on CD4 count. In addition, most such studies have taken place in the developed West. We investigated the association between alcohol use and immune reconstitution through CD4 count response among HIV-infected individuals on antiretroviral therapy (ART) at an urban sub-Saharan Africa…
Preference of Oral Tenofovir Disoproxil Fumarate/Emtricitabine Versus Rectal Tenofovir Reduced-Glycerin 1% Gel Regimens for HIV Prevention Among Cisgender Men and Transgender Women Who Engage in Recep…
Vaginal Ring Use in a Phase 3 Microbicide Trial
Trajectory of use over time of an oral tablet and a rectal gel for HIV prevention among transgender women and men who have sex with men
We examined product adherence among 187 men who have sex with men and transgender women enrolled in a phase II, crossover trial comparing safety and acceptability of an oral tablet and a rectal gel used daily for HIV prevention. Participants reported adherence via daily text messages during 8-week periods. Trajectory analysis identified weekly patterns. Polytomous logistic regression identified characteristics associated with higher probability o…
Pilot evaluation of a standardized patient actor training intervention to improve HIV care for adolescents and young adults in Kenya
Poor retention in HIV care remains a major problem for Adolescents and Young Adults (AYA). A Standardized Patient (SP) clinical training intervention was developed to improve healthcare worker (HCW) "adolescent-friendly" competencies in Kenya. Professional actors were trained to portray HIV-infected AYA according to standardized scripts. HCWs completed a 2-day SP training that included didactic sessions, 7 video-recorded SP encounters, and group …
Birth size and early pneumonia predict linear growth among HIV‐exposed uninfected infants
Stunting remains a global health priority, particularly in sub-Saharan Africa. Identifying determinants of linear growth in HIV-exposed uninfected (HEU) infants can inform interventions to prevent stunting in this vulnerable population. HIV-infected mothers and their uninfected infants were followed monthly from pregnancy to 12-month post-partum in Nairobi, Kenya. Mixed-effects models estimated the change in length-for-age z-score (LAZ) from birt…
A Mixed-Methods Study Examining Adherence to and Acceptability of Intravaginal Rings for HIV Prevention
Newly diagnosed HIV positive children
Newly diagnosed HIV positive children may be unique index cases to identify undiagnosed parents. Data was used from the Pediatric Urgent Start of HAART (NCT02063880) trial, which enrolled hospitalized, ART-naïve, HIV positive children ages 0–12 years in Kenya. Exact McNemar’s tests were used to compare proportions of mothers and fathers tested for HIV, linked to care, and on ART at baseline and 6 months. This analysis included 87 newly diagnosed …
Psychosocial Factors, Condomless Sex, and Detectable Viral Load in HIV-Positive Women in Serodiscordant Couples in Nairobi, Kenya
A Prospective Study of Depressive Symptoms, Condomless Sex, and HIV Viral Load in HIV-Positive Female Sex Workers in Kenya
Derivation of an HIV Risk Score for African Women Who Engage in Sex Work
Antenatal depressive symptoms in Kenyan women living with HIV
Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) in six Kenyan public maternal and child health clinics. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), stigma with the Stigma Scale for Chronic Illness, and intimate partner violence (IPV)…
The Impact of a Comic Book Intervention on East African-American Adolescents’ HPV Vaccine-Related Knowledge, Beliefs and Intentions
Adolescent experiences, perceptions, and preferences for the process of HIV status disclosure in Kenya
Introduction: Disclosure of HIV status to adolescents living with HIV has been associated with improved treatment outcomes. However, there are limited data regarding the experiences of, perceptions of, and preferences for the process of disclosure of HIV status among adolescents and young adults living with HIV (AYLH), especially in sub-Saharan Africa. Methods: Young adults living with HIV from 20 HIV clinics in Kenya who participated in a clinic…
Medicine (31 obras) · HIV/AIDS Research and Interventions (26 obras) · Demography (17 obras) · Environmental health (17 obras) · Family medicine (17 obras) · Adolescent Sexual and Reproductive Health (15 obras) · Population (15 obras) · Public health (15 obras) · Internal Medicine (14 obras) · HIV, Drug Use, Sexual Risk (13 obras)