Walid F Gellad
Dados Biográficos
| ID | 5535458 |
|---|---|
| NOME | Walid F Gellad |
| PRENOMES | Walid F |
| SOBRENOME | Gellad |
| ASSINATURA | GELLAD W F |
| AFILIAÇÕES | University of Pittsburgh |
| ORCID | 0000-0002-6992-5197 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 14 |
| TOTAL DE CITAÇÕES | 2 |
| TOTAL COMO AUTOR | 14 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2012 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2023 |
| ÍNDICE H | 1 |
Estimated Changes in Insulin Prices and Discounts After Entry of New Insulin Products, 2012-2019
In this longitudinal study of US insulin products, results suggest that insulin prices substantially increased from 2012 to 2015, even after accounting for discounts. The introduction of new insulin products was followed by substantial discounting practices that lowered net prices faced by payers
Effect of Different Interventions to Help Primary Care Clinicians Avoid Unsafe Opioid Prescribing in Opioid-Naive Patients With Acute Noncancer Pain
ClinicalTrials.gov Identifier: NCT03537573
Racial and Urban-Rural Difference in the Frequency of Ischemic Stroke as Initial Manifestation of Atrial Fibrillation
Objective: Atrial fibrillation (AF) may remain undiagnosed until the development of complications. We aimed to examine the epidemiology and racial/ethnic and rural/urban differences in the frequency of newly diagnosed AF manifesting as ischemic stroke in a nationally representative sample of Medicare beneficiaries. Methods: We used a 5% random sample of Medicare claims to identify patients newly diagnosed with AF in 2016. The primary dependent va…
Access to Affordable Insulin and Epinephrine Autoinjectors Through Federally Qualified Health Centers
Trump signed the "Executive Order on Access to Affordable Life-Saving Medications," which aimed to improve the affordability of insulin and injectable epinephrine. This executive order applied to federally qualified health centers (FQHCs), a group of nearly 1400 health centers across the country serving approximately 30 million Americans. The executive order requires FQHCs to pass along to patients their 340B discounts on insulin and injectable e…
An Interrupted Time-series Evaluation of the Association Between State Laws Mandating Prescriber Use of Prescription Drug Monitoring Programs and Discontinuation of Chronic Opioid Therapy in US Vetera…
BACKGROUND: Most states have recently passed laws requiring prescribers to use prescription drug monitoring programs (PDMPs) before prescribing opioid medications. The impact of these mandates on discontinuing chronic opioid therapy among Veterans managed in the Veterans Health Administration (VA) is unknown. We assess the association between the earliest of these laws and discontinuation of chronic opioid therapy in Veterans receiving VA health …
Cost and Access Implications of Defining CAR-T Therapy as a Drug
Chimeric antigen receptor T-cell (CAR-T) therapies are groundbreaking, potentially curative treatments that genetically engineer patients' blood cells to target tumors. While CAR-T therapies represent a notable therapeutic advance, their high prices pose a significant barrier to access for patients and a financial strain for hospitals. 1 These prices are set by pharmaceutical companies that
Impact of Dual Use of Department of Veterans Affairs and Medicare Part D Drug Benefits on Potentially Unsafe Opioid Use
Objectives. To estimate the prevalence and consequences of receiving prescription opioids from both the Department of Veterans Affairs (VA) and Medicare Part D. Methods. Among US veterans enrolled in both VA and Part D filling 1 or more opioid prescriptions in 2012 (n = 539 473), we calculated 3 opioid safety measures using morphine milligram equivalents (MME): (1) proportion receiving greater than 100 MME for 1 or more days, (2) mean days receiv…
Pharmacy Use in the First Year of the Veterans Choice Program
BACKGROUND: The Veterans Choice Program (VCP) was created to ensure timely access to health care in the Department of Veterans Affairs (VA). Under this program, medications may be ordered by select non-VA clinicians to be dispensed by VA pharmacies, creating new challenges in ensuring medication safety. OBJECTIVES: To examine pharmaceutical use during the first year of the VCP and to understand barriers and facilitators for VA pharmacists to disp…
An Examination of Claims-based Predictors of Overdose from a Large Medicaid Program
BACKGROUND: Health systems may play an important role in identification of patients at-risk of opioid medication overdose. However, standard measures for identifying overdose risk in administrative data do not exist. OBJECTIVE: Examine the association between opioid medication overdose and 2 validated measures of nonmedical use of prescription opioids within claims data. RESEARCH DESIGN: A longitudinal retrospective cohort study that estimated as…
Lock-In Programs and the Opioid Epidemic
AffiliationsAndrew W. Roberts is with the Department of Pharmacy Sciences, School of Pharmacy and Health Professions, and the Center for Health Services Research and Patient Safety, Creighton University, Omaha, NE. Walid F. Gellad is with the Center for Pharmaceutical Policy and Prescribing, University of Pittsburgh, and the VA Pittsburgh Healthcare System, Pittsburgh, PA. Asheley Cockrell Skinner is with the Duke Clinical Research Institute, Duk…
Who Were the Early Adopters of Dabigatran
BACKGROUND: Variation in physician adoption of new medications is poorly understood. Traditional approaches (eg, measuring time to first prescription) may mask substantial heterogeneity in technology adoption. OBJECTIVE: Apply group-based trajectory models to examine the physician adoption of dabigratran, a novel anticoagulant. METHODS: A retrospective cohort study using prescribing data from IMS XponentTM on all Pennsylvania physicians regularly…
Using Machine Learning to Examine Medication Adherence Thresholds and Risk of Hospitalization
BACKGROUND: Quality improvement efforts are frequently tied to patients achieving ≥80% medication adherence. However, there is little empirical evidence that this threshold optimally predicts important health outcomes. OBJECTIVE: To apply machine learning to examine how adherence to oral hypoglycemic medications is associated with avoidance of hospitalizations, and to identify adherence thresholds for optimal discrimination of hospitalization ris…
Impact of Medicare Part D Plan Features on Use of Generic Drugs
BACKGROUND: Little is known about how Medicare Part D plan features influence choice of generic versus brand drugs. OBJECTIVES: To examine the association between Part D plan features and generic medication use. METHODS: Data from a 2009 random sample of 1.6 million fee-for-service, Part D enrollees aged 65 years and above, who were not dually eligible or receiving low-income subsidies, were used to examine the association between plan features (…
Use of Antipsychotics Among Older Residents in VA Nursing Homes
BACKGROUND: Antipsychotic medications are commonly prescribed to nursing home residents despite their well-established adverse event profiles. Because little is known about their use in Veterans Affairs (VA) nursing homes [ie, Community Living Centers (CLCs)], we assessed the prevalence and risk factors for antipsychotic use in older residents of VA CLCs. METHODS: This cross-sectional study included 3692 Veterans age 65 or older who were admitted…
Lock-In Programs and the Opioid Epidemic
AffiliationsAndrew W. Roberts is with the Department of Pharmacy Sciences, School of Pharmacy and Health Professions, and the Center for Health Services Research and Patient Safety, Creighton University, Omaha, NE. Walid F. Gellad is with the Center for Pharmaceutical Policy and Prescribing, University of Pittsburgh, and the VA Pittsburgh Healthcare System, Pittsburgh, PA. Asheley Cockrell Skinner is with the Duke Clinical Research Institute, Duk…
Use of Antipsychotics Among Older Residents in VA Nursing Homes
BACKGROUND: Antipsychotic medications are commonly prescribed to nursing home residents despite their well-established adverse event profiles. Because little is known about their use in Veterans Affairs (VA) nursing homes [ie, Community Living Centers (CLCs)], we assessed the prevalence and risk factors for antipsychotic use in older residents of VA CLCs. METHODS: This cross-sectional study included 3692 Veterans age 65 or older who were admitted…
Impact of Medicare Part D Plan Features on Use of Generic Drugs
BACKGROUND: Little is known about how Medicare Part D plan features influence choice of generic versus brand drugs. OBJECTIVES: To examine the association between Part D plan features and generic medication use. METHODS: Data from a 2009 random sample of 1.6 million fee-for-service, Part D enrollees aged 65 years and above, who were not dually eligible or receiving low-income subsidies, were used to examine the association between plan features (…
Using Machine Learning to Examine Medication Adherence Thresholds and Risk of Hospitalization
BACKGROUND: Quality improvement efforts are frequently tied to patients achieving ≥80% medication adherence. However, there is little empirical evidence that this threshold optimally predicts important health outcomes. OBJECTIVE: To apply machine learning to examine how adherence to oral hypoglycemic medications is associated with avoidance of hospitalizations, and to identify adherence thresholds for optimal discrimination of hospitalization ris…
Lock-In Programs and the Opioid Epidemic
AffiliationsAndrew W. Roberts is with the Department of Pharmacy Sciences, School of Pharmacy and Health Professions, and the Center for Health Services Research and Patient Safety, Creighton University, Omaha, NE. Walid F. Gellad is with the Center for Pharmaceutical Policy and Prescribing, University of Pittsburgh, and the VA Pittsburgh Healthcare System, Pittsburgh, PA. Asheley Cockrell Skinner is with the Duke Clinical Research Institute, Duk…
Who Were the Early Adopters of Dabigatran
BACKGROUND: Variation in physician adoption of new medications is poorly understood. Traditional approaches (eg, measuring time to first prescription) may mask substantial heterogeneity in technology adoption. OBJECTIVE: Apply group-based trajectory models to examine the physician adoption of dabigratran, a novel anticoagulant. METHODS: A retrospective cohort study using prescribing data from IMS XponentTM on all Pennsylvania physicians regularly…
Pharmacy Use in the First Year of the Veterans Choice Program
BACKGROUND: The Veterans Choice Program (VCP) was created to ensure timely access to health care in the Department of Veterans Affairs (VA). Under this program, medications may be ordered by select non-VA clinicians to be dispensed by VA pharmacies, creating new challenges in ensuring medication safety. OBJECTIVES: To examine pharmaceutical use during the first year of the VCP and to understand barriers and facilitators for VA pharmacists to disp…
An Examination of Claims-based Predictors of Overdose from a Large Medicaid Program
BACKGROUND: Health systems may play an important role in identification of patients at-risk of opioid medication overdose. However, standard measures for identifying overdose risk in administrative data do not exist. OBJECTIVE: Examine the association between opioid medication overdose and 2 validated measures of nonmedical use of prescription opioids within claims data. RESEARCH DESIGN: A longitudinal retrospective cohort study that estimated as…
Impact of Dual Use of Department of Veterans Affairs and Medicare Part D Drug Benefits on Potentially Unsafe Opioid Use
Objectives. To estimate the prevalence and consequences of receiving prescription opioids from both the Department of Veterans Affairs (VA) and Medicare Part D. Methods. Among US veterans enrolled in both VA and Part D filling 1 or more opioid prescriptions in 2012 (n = 539 473), we calculated 3 opioid safety measures using morphine milligram equivalents (MME): (1) proportion receiving greater than 100 MME for 1 or more days, (2) mean days receiv…
Cost and Access Implications of Defining CAR-T Therapy as a Drug
Chimeric antigen receptor T-cell (CAR-T) therapies are groundbreaking, potentially curative treatments that genetically engineer patients' blood cells to target tumors. While CAR-T therapies represent a notable therapeutic advance, their high prices pose a significant barrier to access for patients and a financial strain for hospitals. 1 These prices are set by pharmaceutical companies that
Racial and Urban-Rural Difference in the Frequency of Ischemic Stroke as Initial Manifestation of Atrial Fibrillation
Objective: Atrial fibrillation (AF) may remain undiagnosed until the development of complications. We aimed to examine the epidemiology and racial/ethnic and rural/urban differences in the frequency of newly diagnosed AF manifesting as ischemic stroke in a nationally representative sample of Medicare beneficiaries. Methods: We used a 5% random sample of Medicare claims to identify patients newly diagnosed with AF in 2016. The primary dependent va…
Access to Affordable Insulin and Epinephrine Autoinjectors Through Federally Qualified Health Centers
Trump signed the "Executive Order on Access to Affordable Life-Saving Medications," which aimed to improve the affordability of insulin and injectable epinephrine. This executive order applied to federally qualified health centers (FQHCs), a group of nearly 1400 health centers across the country serving approximately 30 million Americans. The executive order requires FQHCs to pass along to patients their 340B discounts on insulin and injectable e…
An Interrupted Time-series Evaluation of the Association Between State Laws Mandating Prescriber Use of Prescription Drug Monitoring Programs and Discontinuation of Chronic Opioid Therapy in US Vetera…
BACKGROUND: Most states have recently passed laws requiring prescribers to use prescription drug monitoring programs (PDMPs) before prescribing opioid medications. The impact of these mandates on discontinuing chronic opioid therapy among Veterans managed in the Veterans Health Administration (VA) is unknown. We assess the association between the earliest of these laws and discontinuation of chronic opioid therapy in Veterans receiving VA health …
Effect of Different Interventions to Help Primary Care Clinicians Avoid Unsafe Opioid Prescribing in Opioid-Naive Patients With Acute Noncancer Pain
ClinicalTrials.gov Identifier: NCT03537573
Estimated Changes in Insulin Prices and Discounts After Entry of New Insulin Products, 2012-2019
In this longitudinal study of US insulin products, results suggest that insulin prices substantially increased from 2012 to 2015, even after accounting for discounts. The introduction of new insulin products was followed by substantial discounting practices that lowered net prices faced by payers
Medicine (13 obras) · Internal Medicine (10 obras) · Medical prescription (8 obras) · Health care (6 obras) · Internal Medicine (6 obras) · Opioid Use Disorder Treatment (6 obras) · Confidence interval (5 obras) · Emergency Medicine (5 obras) · Family medicine (5 obras) · Medication Adherence and Compliance (5 obras)